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compositionComposition:FLUCONAZOLE-0.3%W/V
prescription
Prescription Medicine
info
Contrex 0.3%W/V Eye/Ear Drops 5Ml

Contrex 0.3%W/V Eye/Ear Drops 5Ml is used to treat fungal infections of eye and ear. It contains Fluconazole, works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections. Contrex 0.3%W/V Eye/Ear Drops 5Ml may cause common side effects like itching, dryness, redness, and burning sensation at the application site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor. Before using Contrex 0.3%W/V Eye/Ear Drops 5Ml, be sure to tell your doctor if you're allergic to any of its ingredients, if you're pregnant or breastfeeding, and about all medications you're taking and any health conditions you have.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUCONAZOLE-0.3%W/V

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

Eye/Ear

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Contrex 0.3%W/V Eye/Ear Drops 5Ml

Contrex 0.3%W/V Eye/Ear Drops 5Ml belongs to the class of antifungals primarily used to treat fungal eye and ear infections. Fungal infections of the eye and ear refer to conditions where fungi overgrow and infect the tissues of the eye (such as the cornea or conjunctiva) or ear (such as the outer ear canal), leading to inflammation, discomfort and potentially serious complications if left untreated.

Contrex 0.3%W/V Eye/Ear Drops 5Ml contains Fluconazole, which kills the fungus/yeast and prevents its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.

Contrex 0.3%W/V Eye/Ear Drops 5Ml should be used as your doctor has advised. It is an external preparation intended for use in the eyes and ears. Sometimes, you may experience common side effects, such as eye/ear burning sensation, ear pain, irritation during administration, and blurred vision. Most of these side effects of Contrex 0.3%W/V Eye/Ear Drops 5Ml do not require medical attention and gradually subside over time. However, if the side effects persist, contact your doctor.

Contrex 0.3%W/V Eye/Ear Drops 5Ml contains benzalkonium as a preservative, so it may cause eye irritation, especially if you have dry eyes or disorders of the cornea (the transparent layer at the front of the eye). After using this medicine, please inform your doctor if you feel stinging or pain in the eye or have abnormal eye sensations. Contrex 0.3%W/V Eye/Ear Drops 5Ml must not be used in the ear if the eardrum is damaged. Consult your doctor before using Contrex 0.3%W/V Eye/Ear Drops 5Ml if you are pregnant or breastfeeding. Contrex 0.3%W/V Eye/Ear Drops 5Ml is not recommended for children unless prescribed by a doctor. Contrex 0.3%W/V Eye/Ear Drops 5Ml may cause temporary vision problems (blurred vision). Be cautious while driving and operating machinery, or avoid doing such activities.

Uses of Contrex 0.3%W/V Eye/Ear Drops 5Ml

Contrex 0.3%W/V Eye/Ear Drops 5Ml is used in the treatment of fungal infections of the ear and eye. The detailed uses of Contrex 0.3%W/V Eye/Ear Drops 5Ml are as follows: 

  • Treats Fungal Ear Infections: Contrex 0.3%W/V Eye/Ear Drops 5Ml helps to eliminate fungal infections in the ear by stopping the growth of fungi, relieving symptoms such as itching, discharge, and discomfort.
  • Manages Fungal Eye Infections: Contrex 0.3%W/V Eye/Ear Drops 5Ml is used to treat fungal infections of the eye, including fungal keratitis, by inhibiting fungal cell membrane formation, thereby stopping the spread of disease. 
  • Reduces Inflammation and Discomfort: By targeting the root cause of the infection, Contrex 0.3%W/V Eye/Ear Drops 5Ml helps reduce inflammation, redness, and irritation in both ear and eye infections.

Key Benefits

Contrex 0.3%W/V Eye/Ear Drops 5Ml offers several medicinal benefits, including the effective treatment of fungal infections of the eyes and ears, the killing of fungus/yeast, and the prevention of their growth. Additionally, it relieves symptoms such as itching, redness, and discomfort, and helps prevent the spread of infection. It ultimately supports the healing process of infected tissues.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication for effective results.
  • Eye drops: Apply Contrex 0.3%W/V Eye/Ear Drops 5Ml to the affected eye/eyes. Wash your hands thoroughly with water before and after use. Tilt your head backwards and pull down the lower eyelid to create a small sac. Squeeze the prescribed amount of dose into the sac using the dropper. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the tip of the dropper after use. Place the dropper back on the bottle and tighten the cap.
  • Ear drops: Instil 2-3 drops into the ear canal; do not touch the tip of the dropper. Always take this medicine exactly as your doctor has told you. Check with your doctor if you are not sure.
  • Do not touch the dropper tip to the eye to prevent contamination.
  • When not in use, keep the bottle tightly closed and upright.

How Contrex 0.3%W/V Eye/Ear Drops 5Ml Works

Contrex 0.3%W/V Eye/Ear Drops 5Ml contains Fluconazole, which kills the fungus/yeast and prevents its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.
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Alcohol

Caution

The interaction of Contrex 0.3%W/V Eye/Ear Drops 5Ml with alcohol is unknown. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

The safety of Contrex 0.3%W/V Eye/Ear Drops 5Ml in pregnant women is unknown. Please consult your doctor, who will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Consult your doctor; no substantial research is yet on using Contrex 0.3%W/V Eye/Ear Drops 5Ml in breastfeeding/nursing mothers.

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Driving

Caution

Drive with caution, Contrex 0.3%W/V Eye/Ear Drops 5Ml. It is better to avoid driving as Contrex 0.3%W/V Eye/Ear Drops 5Ml usually causes temporarily blurred vision and affects your driving ability. Drive only when you are alert and have clear vision. Causes temporarily blurred vision and affects driving ability.

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Liver

Caution

Inform your doctor before receiving the Contrex 0.3%W/V Eye/Ear Drops 5Ml if you have a history of liver impairment/disorder. Your doctor will prescribe it only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Contrex 0.3%W/V Eye/Ear Drops 5Ml if you have a history of kidney impairment/disorder. Your doctor will prescribe it only if the benefits outweigh the risks.

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Children

Caution

Limited information is available regarding the usage of Contrex 0.3%W/V Eye/Ear Drops 5Ml in children, so do not use it unless recommended by the doctor.

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Heart

Caution

Inform your doctor before receiving the Contrex 0.3%W/V Eye/Ear Drops 5Ml if you have a history of heart disease. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Contrex 0.3%W/V Eye/Ear Drops 5Ml in geriatric patients. Please consult your physician.

What if I have taken an overdose of Contrex 0.3%W/V Eye/Ear Drops 5Ml

For Ear(s): If you accidentally put too much Contrex 0.3%W/V Eye/Ear Drops 5Ml in your ear(s), immediately rinse your ear(s) with warm water. If you think that you or someone else has swallowed any or all of the contents of Contrex 0.3%W/V Eye/Ear Drops 5Ml, or used too many drops, immediately call your doctor for advice or go to your nearest hospital. Do this even if there are no signs of discomfort or poisoning.
For Eye(s): Due to low expected systemic passage of Contrex 0.3%W/V Eye/Ear Drops 5Ml, overdose is not likely. However, the risk of overdose cannot be excluded. In case of overdose, rinse with water or 0.9% normal saline solution. Call your doctor or get medical care.

Diet & Lifestyle Advise

Eye infections:

  • To naturally renew your eyes, get at least six to eight hours of sleep each night.
  • You should wash your eyes with clean water at least twice or thrice daily. If you have had eye surgery, wait at least two weeks before washing your eyes.
  • Take care of your health, eat a balanced diet, exercise regularly, and rest well.
  • Regularly wash your hands. Keep unclean hands away from your eyes.
  • Do not rub your eyes.
  • Eyeliner, mascara, and kohl should not be shared.
  • Wipe your eyes and face with clean towels or tissues at all times.
  • If you wear contact lenses, clean them and replace them more frequently. Never share your contact lenses. Always wash your hands before and after inserting and removing them.
  • Avoid gazing at digital screens for extended periods.
  • Blink frequently to aid in the spread of hydrating substances like mucus and tears across the eyes.

Ear infections:

  • Immunity helps prevent infection. To strengthen your immune system, eat fruits and vegetables, high-quality proteins, and whole wheat grains.
  • Avoid consuming foods that you are allergic to,, as this can cause the body to produce excessive mucus, which can result in inflammation.
  • Avoid getting shampoo, soap, and water in the ear because they can cause itching.
  • Poking or scratching the ear can cause damage to the ear canal, resulting in inflammation.
  • Quit or limit the intake of caffeine and alcohol.

Have a query?

How Soon It Starts Working

  • The time required for Contrex 0.3%W/V Eye/Ear Drops 5Ml to start to work: The exact onset time of Contrex 0.3%W/V Eye/Ear Drops 5Ml has not been clinically established. 
  • The time for which the effects of Contrex 0.3%W/V Eye/Ear Drops 5Ml last: The duration of Contrex 0.3%W/V Eye/Ear Drops 5Ml’s effect is clinically not established.

What if you forget to take Contrex 0.3%W/V Eye/Ear Drops 5Ml

If you miss a dose, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the next dose at the regular time. Do not use a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Contrex 0.3%W/V Eye/Ear Drops 5Ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not use Contrex 0.3%W/V Eye/Ear Drops 5Ml if you are allergic to any of the components present in Contrex 0.3%W/V Eye/Ear Drops 5Ml. Before using Contrex 0.3%W/V Eye/Ear Drops 5Ml, inform your doctor if you have vision problems, severe eye pain, glaucoma (high blood pressure), eye damage, eye surgery, hearing problems (cytotoxicity), or a perforated eardrum and chronic otitis media. Notify the doctor if you are pregnant, planning to become pregnant, or are breastfeeding. Contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug interactions: Relevant interactions could not be found/established.

Drug-Food interactions: Relevant interactions could not be found/established.

Drug-Disease interactions: Inform your doctor if you have vision problems, severe eye pain, glaucoma (high blood pressure), eye damage, eye surgery, hearing problems (cytotoxicity), perforated eardrum and chronic otitis media.

FluconazoleEliglustat
Critical
FluconazoleErythromycin
Critical

Drug-Drug Interactions

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FluconazoleEliglustat
Critical
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
When Eliglustat and Contrex 0.3%W/V Eye/Ear Drops 5Ml are taken together, Contrex 0.3%W/V Eye/Ear Drops 5Ml can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
When Lomitapide is taken with Contrex 0.3%W/V Eye/Ear Drops 5Ml, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
When Astemizole is taken with Contrex 0.3%W/V Eye/Ear Drops 5Ml, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleAmisulpride
Severe
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Taking Amisulpride with Contrex 0.3%W/V Eye/Ear Drops 5Ml may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Amisulpride can be taken with Contrex 0.3%W/V Eye/Ear Drops 5Ml if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue any medications without consulting a doctor.
FluconazoleWarfarin
Severe
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Co-administration of Warfarin with Contrex 0.3%W/V Eye/Ear Drops 5Ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Contrex 0.3%W/V Eye/Ear Drops 5Ml and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
FluconazoleAlfentanil
Severe
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Co-administration of Alfentanil and Contrex 0.3%W/V Eye/Ear Drops 5Ml may significantly increase the blood levels of ALfentanil which may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Alfentanil and Contrex 0.3%W/V Eye/Ear Drops 5Ml, you can take these medicines together if prescribed by a doctor. These symptoms include feeling very tired, having trouble breathing, feeling dizzy or lightheaded, having low blood pressure, having an irregular heartbeat, or having any other problems. Do not stop using any medications without a doctor's advice.
FluconazoleMoxifloxacin
Severe
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Moxifloxacin can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Contrex 0.3%W/V Eye/Ear Drops 5Ml can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience dizziness, shortness of breath, or irregular heartbeat consult a doctor. Do not discontinue the medications without consulting a doctor.
FluconazoleVemurafenib
Severe
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with vemurafenib may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Contrex 0.3%W/V Eye/Ear Drops 5Ml can be taken with vemurafenib if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without a doctor's advice.
FluconazoleRibociclib
Severe
How does the drug interact with Contrex 0.3%W/V Eye/Ear Drops 5Ml:
Taking Contrex 0.3%W/V Eye/Ear Drops 5Ml with Ribociclib may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Contrex 0.3%W/V Eye/Ear Drops 5Ml can be taken with Ribociclib if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Contrex 0.3%W/V Eye/Ear Drops 5Ml is used to treat fungal infections of the eye and ear.
Contrex 0.3%W/V Eye/Ear Drops 5Ml contains Fluconazole, which inhibits the formation of the fungal cell membrane, ultimately killing the fungus or yeast and preventing its growth.
Using eye drops for too long can cause irritation, increase the risk of side effects, and even lead to new infections. It's best to follow the doctor's instructions and only use the drops as directed.
You should be cautious when using Contrex 0.3%W/V Eye/Ear Drops 5Ml if you're pregnant or breastfeeding or if you have allergies to any ingredient present in Contrex 0.3%W/V Eye/Ear Drops 5Ml. Additionally, if you have liver or kidney disease or other eye/ear infections or conditions, consult your doctor before using the drops.
Never stop the treatment with Contrex 0.3%W/V Eye/Ear Drops 5Ml on your own, as the infection may come back again (relapse) if the prescribed treatment is not completely taken before stopping Contrex 0.3%W/V Eye/Ear Drops 5Ml. Discuss this with your doctor.
When dealing with eye/ear infections, taking precautions is essential to prevent further contamination and worsening of the infection. Avoid touching the applicator tip of Contrex 0.3%W/V Eye/Ear Drops 5Ml to any surface, including your eyes, ears, fingers, or other objects. Additionally, refrain from sharing personal items, such as towels or clothing, until the infection clears. It's also best to avoid wearing contact lenses, as they can exacerbate eye infections, and refrain from inserting cotton swabs or bobby pins into your ears, as this can worsen ear infections.
Like any medication, Contrex 0.3%W/V Eye/Ear Drops 5Ml may cause side effects, although not everyone will experience them. Common side effects include a burning sensation in the eyes or ears, ear pain, irritation upon application, and blurred vision. These effects are typically temporary and may subside shortly after use. If you notice any unusual or severe symptoms, contact your doctor immediately.
Contrex 0.3%W/V Eye/Ear Drops 5Ml should be stored in a cool and dry place, away from direct heat or sunlight. Keep the container tightly closed and out of reach of children. Do not freeze this medication.

Disclaimer

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Reference

  1. Fluconazole Fluconazole. 2014. [Accessed on 29 Mar. 2019] Check here
  2. Diflucan 150 Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 17 November 2021] Check here
  3. DIFLUCAN Tablets/Oral Suspension USP [Internet]. Accessdata.fda.gov. 2021 [Accessed on 17 November 2021] Check here
  4. Diflucan 150 Capsules - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 17 November 2021] Check here
  5. Ameish Govindarajan; Karlyle G. Bistas; Curtis J. Ingold; Ayham Aboeed. NIH National Library of Medicine, National center for biotechnology information. June 2022. [Accessed on 4th December 2025] Check here
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 29 Mar. 2019] Check here
  7. Diflu Eye Drop. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Other Info - CON0504

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