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compositionComposition:MESALAZINE-1.2GM
prescription
Prescription Medicine
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Coolgut Tablet is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MESALAZINE-1.2GM

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Coolgut Tablet

Coolgut Tablet is a prescription medicine used to treat and manage mild-to-moderate inflammatory bowel conditions, primarily ulcerative colitis. It works directly in the gut to reduce swelling, redness, and tissue damage in the lining of the large intestine. By controlling this irritation, it helps soothe symptoms like abdominal pain and frequent diarrhoea.

For the best results, you should take Coolgut Tablet consistently every day, exactly as prescribed by your healthcare provider, even when you are feeling well. These tablets are typically taken with food, though some specific formulations may vary, so it is important to check your prescription label. Alongside your medication, eating a balanced diet, staying hydrated, and avoiding known food triggers can significantly improve your gut health.

While taking Coolgut Tablet , you may experience mild and temporary side effects like headaches, mild stomach pain, or nausea. However, if you experience more serious issues such as severe abdominal cramps, worsening diarrhoea, fever, or a persistent headache, you should consult your doctor immediately.

Before starting this treatment, tell your doctor if you have a history of kidney problems, liver damage, or asthma. Do not take this if you are allergic to aspirin or any other salicylate medications, as this can trigger a severe allergic reaction.

This medicine can interact with certain other treatments, such as water pills or pain relievers, which can increase the strain on your kidneys. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe and appropriate for your specific needs.

Uses of Coolgut Tablet

Coolgut Tablet is used to treat and manage mild-to-moderate inflammatory bowel conditions. The detailed uses of Coolgut Tablet are as follows:

  • Ulcerative Colitis: It helps reduce swelling, redness, and inflammation in the lining of the large intestine to bring active flare-ups under control.
  • Maintenance of Remission: It is used long-term to keep the disease inactive and prevent symptoms like abdominal pain and diarrhoea from returning.

Key Benefits

Coolgut Tablet helps manage inflammatory bowel disease by reducing inflammation in the intestines. With regular use as prescribed, it helps relieve digestive symptoms, promote healing of the bowel lining, and maintain long-term remission.

  • Reduces Intestinal Inflammation: By acting directly on the inflamed bowel lining, this medicine helps relieve abdominal cramping, urgent bowel movements, rectal bleeding, and other symptoms of intestinal inflammation.
  • Promotes Healing of the Digestive Tract: As inflammation decreases, this medicine supports healing of the intestinal lining, helping restore normal bowel function and improve daily comfort.
  • Helps Maintain Long-Term Remission: Regular use helps keep the condition under control, reducing the frequency of flare-ups and allowing you to enjoy longer periods with few or no symptoms.
Side effects of Coolgut Tablet
  • Eating and drinking slowly can help swallow less air, which reduces burps.
  • Avoid consuming foods like gum and hard candy and drinking carbonated drinks as they release carbon dioxide gas in your body.
  • Prevent smoking as it can impact your whole body.
  • Seek medical help to treat gastric problems and heart burn that may lead to frequent burps.
  • Check your dentures because if they are loosely fit, excess air can be swallowed that causes burbs more frequently.
  • If you have bowel inflammation, eat smaller quantities and more frequent meals.
  • Eat slowly and chew your food thoroughly to help digestion.
  • Eat fiber-rich foods such as fruits, whole grains, and vegetables to promote regular bowel movements.
  • Avoid gas-producing foods like cabbage, beans, broccoli and carbonated drinks.
  • Drink lots of water throughout the day to prevent dehydration and aid digestion.
  • Do regular exercise to enhance digestion and reduce bloating.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

  • Coolgut Tablet can be taken 1 hour before or 2 hours after a meal to prevent stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication, as it may differ from person to person.
  • Swallow the whole tablet with a glass of water.
  • Do not crush, chew, or break it.

How Coolgut Tablet Works

Coolgut Tablet contains the active ingredient mesalazine, which belongs to a class of anti-inflammatory medicines. Unlike general anti-inflammatory pills that work throughout your whole body, these tablets are specifically designed to travel down to your bowels before releasing the active medicine. Once it reaches the large intestine, the medicine works locally on the gut wall to block the production of certain natural chemicals that cause swelling, irritation, and tissue damage. By stopping these inflammatory chemicals at the source, Coolgut Tablet allows the bowel lining to heal and recover.
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Alcohol

Consult your doctor

It is unknown whether it is safe to consume alcohol with Coolgut Tablet . However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Consult your doctor

Coolgut Tablet should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Caution

Coolgut Tablet should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother.

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Driving

Safe if prescribed

Coolgut Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor if you have liver problems before using Coolgut Tablet .

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Kidney

Caution

Inform your doctor before taking Coolgut Tablet if you have a history of kidney diseases/conditions. Coolgut Tablet should be used with extreme caution in patients with mild to moderate kidney impairment. It is recommended not to take Coolgut Tablet if you have severe kidney impairment.

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Children

Caution

Coolgut Tablet is not recommended for use in children below 6 yeras of age as the safety and efficacy for this medicine is not established. For children above 6 years, the physician will recommed it if necessary.

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Heart

Caution

Coolgut Tablet can rarely cause heart inflammation, so it's important to be cautious if you already have heart problems. Always consult your doctor before taking it to ensure it's safe for your condition.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Coolgut Tablet , as there is limited information available on its safety in this age group.

What if I have taken an overdose of Coolgut Tablet

If you suspect an overdose or experience severe symptoms like confusion, rapid breathing, or extreme dizziness, seek immediate medical attention or call emergency services right away.

Diet & Lifestyle Advise

  • Keep a food diary: Track what you eat to identify and avoid foods that trigger your symptoms, such as spicy, greasy, or highly processed meals.
  • Eat smaller meals: Consuming smaller, more frequent meals throughout the day can be gentler on your digestive tract than three large meals.
  • Stay well hydrated: Drink plenty of water daily, especially during flare-ups, to replace fluids lost from diarrhoea.
  • Manage stress: Stress can trigger gut inflammation. Practice relaxation techniques like deep breathing, yoga, or light exercise to support your overall gut health.

Health Queries

I have acute ulcerative colitis and have been taking Coolgut 1.2 g along with folic acid 5 mg for over a year. How should I take other medicines for this condition?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

For acute ulcerative colitis (inflammation and ulcers in the lining of the large intestine), any additional medications, such as steroids or immunosuppressants, must be carefully prescribed by your doctor or gastroenterologist according to your current symptoms. It is important to continue taking Coolgut (Mesalazine) exactly as directed, even when your symptoms are under control, to prevent flare-ups and maintain gut health. Always consult your doctor before starting new medicines, and attend regular follow-ups to adjust treatment if needed.
health query

Have a query?

How Soon It Starts Working

The time required for Coolgut Tablet to start to work: The time required for Coolgut Tablet to show its action is unknown. The time for which the effects of Coolgut Tablet last: The duration of action for Coolgut Tablet is unknown.

What if you forget to take Coolgut Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular routine. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Coolgut Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your stools: Some tablets are designed to release medicine slowly. If you consistently notice empty tablet shells in your stool, speak to your doctor.
  • Monitor kidney function: Your doctor will likely order routine blood and urine tests to monitor your kidney and liver health while you are on this medication.
  • Watch for salicylate sensitivity: If you have ever had a bad reaction to aspirin, do not start taking Coolgut Tablet and inform your healthcare provider immediately.
  • Do not stop abruptly: Even if you feel completely healthy, stopping this medication suddenly can cause your bowel inflammation to return.
  • Check the tablet condition: Ensure the tablet is intact before taking it; do not take tablets that are chipped, cracked, or damp.

Drug-Drug Interactions

verifiedApollotooltip
  • Aspirin and NSAIDs (like ibuprofen): Taking these together with Coolgut Tablet may significantly increase the risk of kidney damage.
  • Azathioprine or 6-mercaptopurine: Combining these medications can increase the risk of bone marrow suppression, leading to low blood cell counts.
  • Antacids or Proton Pump Inhibitors (like omeprazole): These can alter stomach acid levels and cause the protective coating on Coolgut Tablet to break down too early in the digestive tract.
MesalazineCidofovir
Critical
MesalazineNizatidine
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Coolgut Tablet:
Co-administration of Coolgut Tablet with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Coolgut Tablet with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Nizatidine with Coolgut Tablet can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Coolgut Tablet with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Iodamide with Coolgut Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Iomeprol with Coolgut Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Coolgut Tablet and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Metrizamide with Coolgut Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Coolgut Tablet with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of omeprazole with Coolgut Tablet can decrease the effects of Coolgut Tablet.

How to manage the interaction:
There could be a possible interaction between Coolgut Tablet and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Ranitidine with Coolgut Tablet can decrease the levels of Coolgut Tablet, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Coolgut Tablet with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Tenofovir alafenamide with Coolgut Tablet may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Coolgut Tablet with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Coolgut Tablet:
Co-administration of Deferasirox with Coolgut Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Coolgut Tablet and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Coolgut Tablet when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Coolgut Tablet is used to treat Ulcerative colitis and Crohn's disease.
Coolgut Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
You are not recommended to take Coolgut Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Coolgut Tablet with other medicines.
Coolgut Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Coolgut Tablet .
Yes, Coolgut Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Coolgut Tablet to prevent dehydration.
No, you must swallow the tablets whole. Crushing or chewing them destroys the special protective coating designed to ensure the medicine reaches your large intestine before dissolving. Talk to your doctor if you have trouble swallowing tablets.
No, you should not take this medication if you have a known allergy to aspirin or other salicylates. Doing so can cause a severe allergic reaction. Talk to your doctor to find an alternative treatment.
While there is no direct interaction between alcohol and this medicine, alcohol can irritate your digestive tract and worsen symptoms of bowel inflammation. It is best to limit or avoid alcohol. Talk to your doctor for personalised advice.
Yes, many women continue taking this medicine during pregnancy to keep their bowel disease in remission, but it must be done under close medical supervision. Talk to your doctor to weigh the benefits and potential risks.
Some extended-release tablets may pass through your body looking intact after the active medicine has been absorbed. However, if this happens regularly, talk to your doctor or pharmacist to ensure you are receiving the proper dose.
Weight gain is not a common side effect of this medication. However, as your gut heals and your appetite improves, you may experience some natural weight recovery. Talk to your doctor if you have concerns about weight changes.
Yes. Coolgut Tablet can rarely affect kidney function and may also be associated with kidney stones in some patients. Your doctor may recommend regular kidney-function tests during treatment. Drink adequate fluids unless your doctor has advised otherwise. Contact your doctor if you develop changes in urination, blood in the urine, severe side pain, or other symptoms of kidney problems.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - COO0034

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