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compositionComposition:CLOPIDOGREL-75MG
prescription
Prescription Medicine
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Corel-75 Tablet is used for the prevention of heart attack or stroke in people at high risk of heart disease. It contains Clopidogrel, which helps in preventing the formation of harmful blood clots (plaque) in your veins. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, it helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, or peripheral arterial disease (heart problem due to narrowed blood vessels). In some cases, you may experience side effects such as nosebleeds, heavier periods, bleeding gums, easy bruising, diarrhoea, stomach pain, indigestion, or heartburn. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CLOPIDOGREL-75MG

Manufacturer/Marketer :

Kaiser Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Corel-75 Tablet

Corel-75 Tablet is a prescription medicine used to help prevent blood clots in individuals who have recently experienced a heart attack, stroke, or have peripheral arterial disease. By reducing the formation of harmful blood clots, it helps lower the risk of future cardiovascular events and supports healthy blood flow through the arteries.

Take Corel-75 Tablet exactly as prescribed by your doctor, usually once daily at the same time each day. This medicine can be taken with or without food. Taking it regularly, along with a heart-healthy diet, regular physical activity, and other lifestyle measures recommended by your doctor, helps maximise its protective benefits.

Some people may experience mild side effects such as easy bruising, nosebleeds, or minor cuts that take longer than usual to stop bleeding. These effects are generally expected because the medicine reduces the blood's ability to form clots. However, contact your doctor immediately if you notice severe or unexplained bleeding, blood in your urine or stools, or any other unusual bleeding symptoms.

Before taking Corel-75 Tablet , inform your doctor if you have a history of stomach ulcers, bleeding disorders, liver disease, or any medical condition that increases your risk of bleeding. This medicine should not be used if you currently have active bleeding, such as a bleeding stomach ulcer or bleeding inside the brain. Your doctor may recommend regular monitoring depending on your medical history and overall health.

Certain medicines, including blood thinners, some antidepressants, and specific stomach-acid reducing medicines, can affect how well Corel-75 Tablet works or increase the risk of bleeding. Excessive alcohol consumption may also increase the likelihood of stomach bleeding. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor to determine whether this medicine is appropriate for you.

Uses of Corel-75 Tablet

Corel-75 Tablet is used to help prevent harmful blood clots and reduce the risk of serious cardiovascular complications. The detailed uses of Corel-75 Tablet are as follows:

  • Recent Heart Attack: Corel-75 Tablet helps reduce the risk of future heart attacks by preventing platelets from clumping together and forming blood clots within the arteries.
  • Recent Ischaemic Stroke: It helps lower the risk of recurrent strokes by reducing the formation of blood clots that can block blood flow to the brain.
  • Peripheral Arterial Disease: Corel-75 Tablet helps improve blood flow in narrowed arteries of the legs and other limbs, reducing the risk of clot-related complications.
  • Acute Coronary Syndrome: It is commonly used after conditions such as unstable angina or a heart attack to help prevent further clot formation and reduce the risk of additional cardiovascular events.
  • After Coronary Stent Placement: Corel-75 Tablet is often prescribed following stent implantation to help prevent clots from forming inside the stent and to maintain adequate blood flow through the treated artery.
     

Key Benefits

Clopidogrel in Corel-75 Tablet helps protect against the formation of harmful blood clots that can block blood flow to vital organs. By supporting smoother blood circulation, it plays an important role in reducing the risk of serious cardiovascular complications and improving long-term vascular health.

  • Helps Prevent Heart Attacks and Strokes: By reducing platelet clumping, Corel-75 Tablet lowers the likelihood of blood clots forming inside arteries that supply the heart and brain.
  • Supports Healthy Blood Flow: This medicine helps keep blood moving more freely through the blood vessels, reducing the risk of clot-related blockages and supporting adequate oxygen delivery to tissues.
  • Protects Against Recurrent Cardiovascular Events: For people who have previously experienced a heart attack, stroke, or acute coronary syndrome, regular use of Corel-75 Tablet helps reduce the risk of future clot-related complications.
  • Helps Maintain Stent Patency: When prescribed after coronary stent placement, Corel-75 Tablet helps prevent clot formation within the stent, supporting uninterrupted blood flow through the treated artery.
  • Supports Long-Term Cardiovascular Health: Consistent treatment with Corel-75 Tablet helps lower the likelihood of serious cardiovascular events, hospitalisations, and emergency interventions related to blood clot formation.
     

Directions for Use

Take Corel-75 Tablet exactly as directed by your doctor. Follow these simple steps for safe administration:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed in your body.
  • You can take this medicine with or without food, but try to take it at the exact same time every day to establish a consistent routine.

Always follow your doctor's exact instructions regarding your dose and how long you need to take this medication. Do not stop taking it suddenly without consulting your doctor, even if you feel well, as stopping can increase your risk of a heart attack or stroke.
 

How Corel-75 Tablet Works

Corel-75 Tablet contains clopidogrel, an antiplatelet medicine that helps prevent harmful blood clots from forming inside your blood vessels. It is converted in the liver into its active form, which then blocks a specific receptor on platelets called the P2Y12 receptor. This prevents platelets from receiving the signals that make them stick together and form clots. By reducing platelet clumping, Corel-75 Tablet helps keep blood flowing smoothly through the arteries and lowers the risk of clot-related complications such as heart attacks, strokes, and stent blockage. It does not dissolve existing clots but helps prevent new ones from forming.
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Alcohol

Caution

You can drink alcohol with Corel-75 Tablet . But do not drink too much while taking this medicine. It can irritate your stomach.

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Pregnancy

Consult your doctor

Limited information is available about the use of Corel-75 Tablet in pregnant women. Therefore, please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Consult your doctor

Limited information is available about the use of Corel-75 Tablet in breastfeeding mothers. Therefore, please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Safe if prescribed

Corel-75 Tablet has no or negligible influence on the ability to drive or use machines.

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Liver

Safe if prescribed

No dosage adjustment is necessary in patients with liver disease.

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Kidney

Caution

Corel-75 Tablet should be taken with caution, especially if you have a history of kidney disease. Your doctor may have to adjust the dose.

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Children

Unsafe

The safety and effectiveness of Corel-75 Tablet have not been established in children due to limited testing of this drug on children by competent authorities across the world. Hence, Corel-75 Tablet is not recommended for use in children.

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Heart

Safe if prescribed

Corel-75 Tablet can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and stroke. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Corel-75 Tablet should be used in elderly people only if prescribed by the physician.

What if I have taken an overdose of Corel-75 Tablet

Do not take more than the prescribed dose of Corel-75 Tablet as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid Certain Pain Relievers: Avoid taking aspirin, ibuprofen, naproxen, or other pain relievers unless specifically recommended by your doctor, as they may increase your risk of bleeding while taking Corel-75 Tablet .
  • Be Careful with Sharp Objects: Be careful when using sharp objects such as razors, knives, or scissors. Using an electric razor and a soft-bristled toothbrush may help reduce the risk of cuts and bleeding.
  • Limit Alcohol Consumption: Limit alcohol consumption, as alcohol may irritate the stomach lining and increase the risk of stomach bleeding.
  • Follow a Heart-Healthy Diet: Eat a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats to support cardiovascular health.
  • Stay Physically Active: Engage in regular physical activity as advised by your doctor to help improve circulation and reduce cardiovascular risk factors.
  • Inform Healthcare Providers: Inform doctors, dentists, and other healthcare professionals that you are taking Corel-75 Tablet before any medical or dental procedure.
     
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How Soon It Starts Working

The time required for Corel-75 Tablet to start to work: Corel-75 Tablet ideally shows its action within 2 hours after administration. The time for which the effects of Corel-75 Tablet last: The effect of Corel-75 Tablet lasts for 12 hours.

What if you forget to take Corel-75 Tablet

If you forget to take a dose of Corel-75 Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not take a double dose to make up for the missed one.

Storage

•Store Corel-75 Tablet tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). • Keep the medication in its original packaging to protect it from moisture and direct light.

Drug Warnings

  • Inspect the Medicine Before Use: Always check the packaging before taking a dose to ensure the tablets are intact and have not changed colour or deteriorated.
  • Carry Medical Identification: Wear a medical alert bracelet or carry a card stating that you take Corel-75 Tablet so healthcare professionals are aware of your treatment during emergencies.
  • Seek Medical Attention After Major Injuries: Contact your doctor immediately if you experience a fall, a blow to the head, or any significant injury, even if there is no visible bleeding, as internal bleeding may occur.
  • Do Not Stop Treatment Without Medical Advice: Do not stop taking Corel-75 Tablet without consulting your cardiologist or prescribing doctor, especially if you have recently had a stent placed, as stopping treatment prematurely may increase the risk of stent clotting.
  • Inform Your Doctor Before Medical Procedures: Let your doctor know if you are scheduled for any medical tests or procedures, as you may need to stop taking Corel-75 Tablet several days beforehand.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Corel-75 Tablet :

  • Blood Thinners and Anticoagulants: Medicines such as warfarin, apixaban, rivaroxaban, or heparin may increase the risk of bleeding when taken with Corel-75 Tablet .
  • NSAIDs and Pain Relievers: Medicines such as ibuprofen, naproxen, or diclofenac may increase the risk of stomach irritation, ulcers, and bleeding.
  • Certain Proton Pump Inhibitors: Medicines such as omeprazole and esomeprazole may reduce the effectiveness of Corel-75 Tablet by interfering with its activation in the liver.
  • Selective Serotonin Reuptake Inhibitors (SSRIs): Antidepressants such as fluoxetine, sertraline, and paroxetine may increase the risk of bleeding when used together with Corel-75 Tablet .
  • Aspirin: Aspirin may increase the risk of bleeding when combined with Corel-75 Tablet . However, some patients may be intentionally prescribed both medicines together under medical supervision.

Drug-Food Interactions

The following foods and beverages may interact with Corel-75 Tablet and affect its safety or effectiveness:

  • Alcohol: Excessive alcohol consumption may increase the risk of stomach irritation and bleeding while taking Corel-75 Tablet .
  • Grapefruit Products: The effect of grapefruit or grapefruit juice on Corel-75 Tablet is not fully established. Consult your doctor before making significant dietary changes involving grapefruit products while taking this medicine.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Corel-75 Tablet , as it may worsen your condition or require additional monitoring:

  • Active Bleeding Disorders: Corel-75 Tablet should not be used in patients with active bleeding, such as a bleeding stomach ulcer or bleeding inside the brain, as it may lead to serious or life-threatening bleeding.
  • Severe Liver Disease: Liver impairment may affect how Corel-75 Tablet is converted into its active form and may increase the risk of bleeding complications.
  • History of Stomach Ulcers or Gastrointestinal Bleeding: Patients with a history of stomach ulcers or digestive tract bleeding may have a higher risk of bleeding while taking this medicine.
  • Recent Major Surgery or Trauma: Conditions associated with an increased risk of bleeding may require careful monitoring and assessment before treatment with Corel-75 Tablet .
     
ClopidogrelSelexipag
Critical
ClopidogrelMifepristone
Critical

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
How does the drug interact with Corel-75 Tablet:
When Selexipag and Corel-75 Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Corel-75 Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
ClopidogrelMifepristone
Critical
How does the drug interact with Corel-75 Tablet:
Taking Corel-75 Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Corel-75 Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelCangrelor
Severe
How does the drug interact with Corel-75 Tablet:
Co-administration of Cangrelor with Corel-75 Tablet and reduce its effectiveness if used at the same time.

How to manage the interaction:
Although taking Corel-75 Tablet with cangrelor can result in an interaction, they can be taken together if prescribed by a doctor. Corel-75 Tablet should be taken after the Cangrelor infusion is complete. Do not stop taking any medication without consulting a doctor.
ClopidogrelApixaban
Severe
How does the drug interact with Corel-75 Tablet:
Coadministration of Corel-75 Tablet and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Corel-75 Tablet and Apixaban, it can be taken if prescribed by a doctor. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), bruising, dizziness, lightheadedness, or headache. Do not discontinue any medications without consulting a doctor
ClopidogrelModafinil
Severe
How does the drug interact with Corel-75 Tablet:
Coadministration of Corel-75 Tablet with modafinil can reduce the effectiveness of Corel-75 Tablet.

How to manage the interaction:
Although taking Corel-75 Tablet with Modafinil may possibly result in interaction, but it can be taken together if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
ClopidogrelProtamine
Severe
How does the drug interact with Corel-75 Tablet:
Taking Protamine with Corel-75 Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Protamine with Corel-75 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelRabeprazole
Severe
How does the drug interact with Corel-75 Tablet:
Taking Corel-75 Tablet with Rabeprazole can reduce the effectiveness of Corel-75 Tablet.

How to manage the interaction:
Taking Corel-75 Tablet and Rabeprazole together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ClopidogrelRamucirumab
Severe
How does the drug interact with Corel-75 Tablet:
The use of ramucirumab together with Corel-75 Tablet may raise the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Corel-75 Tablet and Ramucirumab, you can take these medicines together if prescribed by your doctor. If you notice these signs, contact your doctor immediately - feeling dizzy or lightheaded, dark or bloody stools, coughing, intense headaches, or weakness. Do not discontinue any medications without consulting your doctor.
ClopidogrelPioglitazone
Severe
How does the drug interact with Corel-75 Tablet:
Taking Pioglitazone with Corel-75 Tablet can increases the blood levels of Pioglitazone, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Corel-75 Tablet together with Pioglitazone may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.
ClopidogrelFluvoxamine
Severe
How does the drug interact with Corel-75 Tablet:
Taking fluvoxamine can lower the levels of Corel-75 Tablet in the blood, which can result in a decreased effectiveness of Corel-75 Tablet.

How to manage the interaction:
Taking Corel-75 Tablet and Fluvoxamine together possibly has an interaction, but you can take these medications together if your doctor has advised it. However, if you experience shortness of breath, dizziness, loss of balance, or trouble walking, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS]

FAQs

Corel-75 Tablet is used to prevent heart attack or stroke in people at high risk of heart disease.
Corel-75 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Corel-75 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. It makes blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Corel-75 Tablet helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).
When a blood clot is treated, guidelines recommend that patients take blood thinners for the rest of their lives. If they do not, the chance of developing a second clot is 30 to 40 per cent in the next 10 years.
There might be a problem if you are taking herbal therapies with Corel-75 Tablet , especially those that affect the blood, like Ginkgo Biloba and St John's wort plant extract used as an antidepressant. Together, taking can increase your risk of bleeding. Tell your doctor if you are using any type of herbal supplements before taking Corel-75 Tablet .
Yes, taking Corel-75 Tablet can increase the risk of bleeding as it contains aspirin, which is a blood thinner. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding.
Corel-75 Tablet should be swallowed as a whole with water; do not crush or chew it. Corel-75 Tablet can be taken at any time of the day, but taking it at the same time daily would be better.
Yes, Corel-75 Tablet is a blood thinner. It contains clopidogrel, an antiplatelet medicine that prevents the formation of harmful blood clots.
No, Corel-75 Tablet is not a steroid. It is an antiplatelet medicine.
Corel-75 Tablet might lower the blood pressure. Not everyone experiences this as it is a rare side effect. Consult the doctor if you experience dizziness, blurred vision or light-headedness.
Do not take Corel-75 Tablet if you are allergic to any of its components, have severe liver disease or have a medical condition that causes bleeding such as a stomach ulcer or bleeding within the brain.
Corel-75 Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.
Yes, you can eat food while taking Corel-75 Tablet as it helps lower stomach irritation.
Be cautious while using sharp objects as you may bleed more easily or for a longer time than usual while you are taking Corel-75 Tablet . Let the doctor know that you are taking Corel-75 Tablet if you are due to undergo any surgery or dental procedure.
If you miss a dose of Corel-75 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Consult the doctor before taking other medicines while on treatment with Corel-75 Tablet . Let the doctor know if you are using anticoagulants, painkillers, antidepressants or indigestion medicines.
Side effects of Corel-75 Tablet include diarrhoea, stomach pain, indigestion, heartburn, headache, nausea, vomiting, constipation, and dizziness. Consult the doctor if the side effects persist or worsen.
You should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen while taking Corel-75 Tablet , as they can increase your risk of stomach bleeding. For pain relief, talk to your doctor or pharmacist about safer alternatives.
You may need to stop taking Corel-75 Tablet temporarily before dental procedures or surgery to prevent excessive bleeding. However, never stop taking your medication without first consulting your cardiologist or prescribing doctor. Talk to your doctor for guidance.
Corel-75 Tablet starts working to prevent blood clots within a few hours of your first dose. However, you will not feel any physical change when it is working. It is vital to keep taking it consistently every day. Talk to your doctor if you have questions about your therapy.
It is best to limit or avoid alcohol while taking Corel-75 Tablet . Alcohol can irritate your stomach lining, which increases your risk of developing stomach ulcers or bleeding. Talk to your doctor about what is safe for you.
If you get a minor cut, apply firm, direct pressure with a clean cloth or bandage. It may take longer than usual to stop bleeding. If the bleeding does not stop after several minutes of direct pressure, seek emergency medical attention. Talk to your doctor if you notice frequent bleeding.
The safety of Corel-75 Tablet during pregnancy or breastfeeding is not fully established. You should only take it if your doctor determines the benefit outweighs the potential risk. Talk to your doctor to discuss your options.
Some proton pump inhibitors, such as omeprazole, can reduce the effectiveness of Corel-75 Tablet . Other acid reducers may be safer to use. Talk to your doctor or pharmacist to find a suitable option for your acid reflux.
Stopping Corel-75 Tablet suddenly can significantly increase your risk of blood clots, heart attacks, or strokes, especially if you have a recently placed stent. Never stop this medicine without direct instructions from your doctor. Talk to your doctor if you are experiencing side effects that make you want to stop.

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Country of origin

India

Manufacturer/Marketer address

18/1261 - A1 ESI Road, Palluruthy, Kochi, Kerala-682006.
Other Info - COR0730
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