How does Criticold Plus Syrup 60 ml work?

Criticold Plus Syrup 60 ml contains Paracetamol, Phenylephrine and Chlorpheniramine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases the mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Does Criticold Plus Syrup 60 ml also relieve pain and fever?

Yes, Criticold Plus Syrup 60 ml contains paracetamol which acts as mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

Is Criticold Plus Syrup 60 ml safe to use during breastfeeding?

Criticold Plus Syrup 60 ml is excreted in breast milk and may affect the health of baby. Therefore, if you are breastfeeding, please inform your doctor before taking Criticold Plus Syrup 60 ml so that the doctor may prescribe Criticold Plus Syrup 60 ml if the benefits are greater than risks.

Does Criticold Plus Syrup 60 ml cause drowsiness?

Yes, Criticold Plus Syrup 60 ml may cause drowsiness. It is not necessary for everyone taking Criticold Plus Syrup 60 ml to experience this side effect. Therefore, avoid driving or operate heavy machinery if you feel drowsy after taking Criticold Plus Syrup 60 ml.

Can I take Criticold Plus Syrup 60 ml with an antiallergic medicine (Cetirizine)?

No, you are not recommended to take Criticold Plus Syrup 60 ml with Cetirizine as co-administration of these two medicines may increase sedation and can cause drowsiness, dizziness and difficulty in concentrating. However, please consult a doctor before taking Criticold Plus Syrup 60 ml with other medicines.

Can I stop taking Criticold Plus Syrup 60 ml on my own?

No, you are not recommended to stop taking Criticold Plus Syrup 60 ml without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Criticold Plus Syrup 60 ml for as long as your doctor has prescribed it, and if you experience any difficulty while taking Criticold Plus Syrup 60 ml, please consult your doctor.

In which condition should I avoid taking Criticold Plus Syrup 60 ml?

Do not use Criticold Plus Syrup 60 ml if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Criticold Plus Syrup 60 ml if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Criticold Plus Syrup 60 ml may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness or rash, immediately contact your doctor and stop taking Criticold Plus Syrup 60 ml.

How many Criticold Plus Syrup 60 ml do you need to take in a day?

The number of Criticold Plus Syrup 60 ml doses to be taken daily varies from person to person, depending on factors such as health needs, age, and gender. Take the number of doses of Criticold Plus Syrup 60 ml as a doctor instructed. It's always essential to follow the dosage instructions provided by a healthcare professional, as they consider several factors that are suitable to you before recommending.

What is the difference between Criticold Plus Syrup 60 ml and Paracetamol?

Criticold Plus Syrup 60 ml is a combination medication that contains Paracetamol, Phenylephrine and Chlorpheniramine used to treat symptoms of the common cold or flu. Whereas Paracetamol is a single-ingredient medication primarily used to reduce fever and relieve mild to moderate pain, such as headaches, muscle aches, or toothaches.

What is Criticold Plus Syrup 60 ml?

Criticold Plus Syrup 60 ml combines Paracetamol, Phenylephrine and Chlorpheniramine, which are used to treat common colds and allergies, including sneezing, runny nose, congestion, fever, and headache.

Is it safe to use Criticold Plus Syrup 60 ml?

Criticold Plus Syrup 60 ml is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid adverse complications.

Can I stop taking Criticold Plus Syrup 60 ml when I am relieved of my symptoms?

You are recommended to stop taking Criticold Plus Syrup 60 ml if your symptoms are relieved only after discussing with your doctor. Generally, it is always best to complete the full prescribed course duration for complete relief. Your doctor will ensure your relieved status, provide guidance based on their observation, and avoid the recurrence of the symptoms.

Can the use of Criticold Plus Syrup 60 ml cause dizziness?

Criticold Plus Syrup 60 ml may cause dizziness in some individuals, as it is a reported side effect. If you experience this, take some rest, as the effect typically resolves over time. However, if you experience severe or continuous dizziness, please inform your doctor promptly.

Can the use of Criticold Plus Syrup 60 ml cause damage to the liver?

Criticold Plus Syrup 60 ml may damage the liver, especially when taken in high doses or for extended periods and with pre-existing liver diseases. Paracetamol, one of the active ingredients in Criticold Plus Syrup 60 ml, can also cause liver damage if not used as directed. To ensure safety, follow your doctor's instructions carefully and inform them if you have any pre-existing liver conditions.

What is the recommended storage condition for the Criticold Plus Syrup 60 ml?

Store Criticold Plus Syrup 60 ml by keeping it cool, dry, and out of sunlight. Make sure to keep it out of the reach of children.

Criticold Plus Syrup 60 ml

₹85

(Inclusive of all Taxes)

₹12.8 Cashback (15%)

Written By Veda Maddala , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Criticold Plus Syrup 60 ml is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also shrinks the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, constipation and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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About Criticold Plus Syrup 60 ml

Criticold Plus Syrup 60 ml is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs or talks.

Criticold Plus Syrup 60 ml is a combination of three drugs, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine (decongestant) and Chlorpheniramine (antihistamine/antiallergic). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that works by shrinking the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and nasal congestion.

Take Criticold Plus Syrup 60 ml as prescribed. Your doctor will recommend you how often you take Criticold Plus Syrup 60 ml based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, constipation and dry mouth. Most of these side effects of Criticold Plus Syrup 60 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Criticold Plus Syrup 60 ml or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Criticold Plus Syrup 60 ml. Do not use Criticold Plus Syrup 60 ml in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Criticold Plus Syrup 60 ml is not recommended for children below 4 years. Please do not take more than the prescribed dose of Criticold Plus Syrup 60 ml as it may cause liver damage and can be lethal. If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Criticold Plus Syrup 60 ml.

Uses of Criticold Plus Syrup 60 ml

Criticold Plus Syrup 60 ml is used in the treatment of Common cold and allergies. The detailed uses of Criticold Plus Syrup 60 ml are as follows: •Cold Symptom Relief: Criticold Plus Syrup 60 ml is commonly used to address symptoms of the common cold, such as nasal congestion, sneezing, and a runny nose, ensuring better comfort. •Fever Reduction: Criticold Plus Syrup 60 ml contains ingredients that help lower fever, making it particularly effective for infections or colds accompanied by elevated body temperatures. •Managing Allergic Rhinitis: Criticold Plus Syrup 60 ml effectively alleviates allergic rhinitis symptoms, including nasal itching, watery eyes, and sinus pressure. •Relieving Sinus Headaches: Criticold Plus Syrup 60 ml can help ease sinus headaches caused by sinusitis by reducing nasal inflammation and congestion. •Cough Management: Criticold Plus Syrup 60 ml provides relief from cough symptoms linked to colds or allergies by reducing mucus production and supporting respiratory health.

Directions for Use

• Criticold Plus Syrup 60 ml can be taken with or without food, as advised by your doctor• It is usually taken every 4 hours. However, follow your doctor's instructions on the dosage and timing of this medication for effective results.• Swallow Criticold Plus Syrup 60 ml as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Criticold Plus Syrup 60 ml is a combination of three drugs: Paracetamol, Phenylephrine and Chlorpheniramine. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that work by contracting and narrowing the blood vessels. Thus, it provides relief from congestion and decreases mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

How Criticold Plus Syrup 60 ml Works

Criticold Plus Syrup 60 ml is a combination of three drugs, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine (decongestant) and Chlorpheniramine (antihistamine/antiallergic). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that works by shrinking the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and nasal congestion.

Storage

Keep Criticold Plus Syrup 60 ml out of the sight and reach of children.

What if I have taken an overdose of Criticold Plus Syrup 60 ml

Do not take more than the prescribed dose of Criticold Plus Syrup 60 ml as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Criticold Plus Syrup 60 ml or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Criticold Plus Syrup 60 ml. Do not use Criticold Plus Syrup 60 ml in breastfeeding mothers without doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Criticold Plus Syrup 60 ml is not recommended for children below 4 years. Please do not take more than the prescribed dose of Criticold Plus Syrup 60 ml as it may cause liver damage and can be lethal. If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Criticold Plus Syrup 60 ml.

Drug-Drug Interactions

PhenylephrineSevoflurane

Critical

PhenylephrineFurazolidone

Critical

Drug-Drug Interactions

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PhenylephrineSevoflurane

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Co-administration of Criticold Plus Syrup 60 ml with Sevoflurane can increase the levels of Criticold Plus Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Criticold Plus Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

PhenylephrineFurazolidone

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Taking Furazolidone with Criticold Plus Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Criticold Plus Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Criticold Plus Syrup 60 ml only after 14 days of stopping Furazolidone.

PhenylephrineSelegiline

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Co-administration of Selegiline with Criticold Plus Syrup 60 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Criticold Plus Syrup 60 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.

PhenylephrinePropofol

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Taking Criticold Plus Syrup 60 ml with Propofol may lead to increased levels of Criticold Plus Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Criticold Plus Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

PhenylephrineTranylcypromine

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Taking Tranylcypromine with Criticold Plus Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Criticold Plus Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.

ChlorpheniraminePotassium citrate

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Taking Criticold Plus Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Criticold Plus Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

ChlorpheniraminePotassium chloride

Critical

How does the drug interact with Criticold Plus Syrup 60 ml:
Taking Criticold Plus Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Criticold Plus Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.

PhenylephrineDoxepin

Severe

How does the drug interact with Criticold Plus Syrup 60 ml:
Taking Doxepin and Criticold Plus Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Doxepin and Criticold Plus Syrup 60 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms, contact your doctor immediately. Regular monitoring of blood pressure is advised. Do not discontinue any medications without a doctor's advice.

PhenylephrineIsocarboxazid

Severe

How does the drug interact with Criticold Plus Syrup 60 ml:
Co-administration of Criticold Plus Syrup 60 ml with Isocarboxazid can result in extremely high blood pressure which may be serious.

How to manage the interaction:
Although taking Isocarboxazid and Criticold Plus Syrup 60 ml together can result in an interaction. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

PhenylephrineHalothane

Severe

How does the drug interact with Criticold Plus Syrup 60 ml:
Co-administration of Criticold Plus Syrup 60 ml with Halothane may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Criticold Plus Syrup 60 ml with Halothane together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms like lightheadedness, fainting, irregular heart beat, dizziness, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Wash your hands with soap and water regularly to prevent the spread of germs.
Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
Drink plenty of fluids to avoid dehydration.
Gargle with salt water for relief from sore throat.
Avoid consumption of alcohol with Criticold Plus Syrup 60 ml as it may cause tiredness, drowsiness or lack of concentration.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

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Alcohol

Unsafe

Avoid consumption of alcohol with Criticold Plus Syrup 60 ml as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Criticold Plus Syrup 60 ml.

Pregnancy

Caution

The safety of Criticold Plus Syrup 60 ml in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

Breast Feeding

Caution

Criticold Plus Syrup 60 ml may be excreted in breast milk, and cause harm to the baby. Besides this, Criticold Plus Syrup 60 ml may also slow milk's production, so it is better to contact a doctor before a lactating mother takes it.

Driving

Caution

Criticold Plus Syrup 60 ml may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking Criticold Plus Syrup 60 ml.

Liver

Caution

Take Criticold Plus Syrup 60 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

Kidney

Caution

Take Criticold Plus Syrup 60 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

Children

Caution

Criticold Plus Syrup 60 ml is not recommended for children below 4 years of age. However, please consult a doctor before giving Criticold Plus Syrup 60 ml to children.

Have a query?

FAQs

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.

Other Info - CRI0206

Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:38 AM IST

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Reference

https://www.drugs.com/mtm/acetaminophen-chlorpheniramine-and-phenylephrine.html#:~:text=Acetaminophen%20is%20a%20pain%20reliever,vessels%20in%20the%20nasal%20passages.

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Lemolinctus-DS Plus Syrup 60 ml

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FAQs

What is the use of Criticold Plus Syrup 60 ml?

How does Criticold Plus Syrup 60 ml work?

Does Criticold Plus Syrup 60 ml also relieve pain and fever?

Can I drink alcohol with Criticold Plus Syrup 60 ml?

Is Criticold Plus Syrup 60 ml safe to use during breastfeeding?

Does Criticold Plus Syrup 60 ml cause drowsiness?

Can I take Criticold Plus Syrup 60 ml with an antiallergic medicine (Cetirizine)?

Can I stop taking Criticold Plus Syrup 60 ml on my own?

In which condition should I avoid taking Criticold Plus Syrup 60 ml?

How many Criticold Plus Syrup 60 ml do you need to take in a day?

What is the difference between Criticold Plus Syrup 60 ml and Paracetamol?

What is Criticold Plus Syrup 60 ml?

Is it safe to use Criticold Plus Syrup 60 ml?

Can I stop taking Criticold Plus Syrup 60 ml when I am relieved of my symptoms?

Can the use of Criticold Plus Syrup 60 ml cause dizziness?

Can the use of Criticold Plus Syrup 60 ml cause damage to the liver?

What is the recommended storage condition for the Criticold Plus Syrup 60 ml?

What are the common side effects of Criticold Plus Syrup 60 ml?

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