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compositionComposition:CLARITHROMYCIN-125MG
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Crixan 125 mg Suspension is used to treat bacterial infections. It contains Clarithromycin, which inhibits the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. Thus, it helps prevent infections. Common side effects of Crixan 125 mg Suspension are feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CLARITHROMYCIN-125MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Crixan 125 mg Suspension

Crixan 125 mg Suspension belongs to a group of medicines called macrolide antibiotics used to treat bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection.

Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.

Crixan 125 mg Suspension may cause side effects, including nausea, diarrhoea, vomiting, loss of appetite, bloating and indigestion, headaches and difficulty sleeping. If any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Crixan 125 mg Suspension unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication.

Uses of Crixan 125 mg Suspension

Crixan 125 mg Suspension is used in the treatment of Bacterial infections. The detailed uses of Crixan 125 mg Suspension are as follows:

  • Respiratory Tract Infections: Crixan 125 mg Suspension is prescribed to treat infections like bronchitis and community-acquired pneumonia. It works by stopping the growth of bacteria in the lungs and airways, helping relieve symptoms such as cough, fever, and breathing difficulty.
  • Ear, Nose, and Throat Infections: Crixan 125 mg Suspension is effective in managing conditions like otitis media (middle ear infection), sinusitis, pharyngitis, and tonsillitis. It helps reduce inflammation, ear pain, sore throat, and fever by eliminating the causative bacteria.
  • Skin and Soft Tissue Infections: Crixan 125 mg Suspension treats mild to moderate skin infections such as cellulitis, impetigo, and infected wounds. It works by targeting the bacteria responsible, reducing redness, swelling, and promoting healing.
  • Dental and Oral Infections: Crixan 125 mg Suspension may be used to treat bacterial infections in the teeth and gums, such as dental abscesses, by controlling bacterial growth and reducing pain and swelling.
  • Infections in Immunocompromised Children: Crixan 125 mg Suspension can be used to treat or prevent infections like Mycobacterium avium complex (MAC) in children with weakened immune systems, such as those with HIV.

Key Benefits

  • Crixan 125 mg Suspension belongs to the macrolide class of antibiotics. It is used to treat bacterial infections in children.
  • It is effective against a broad spectrum of bacteria, including gram-positive, gram-negative bacteria and anaerobes.
  • It helps relieve infection by killing infection-causing bacteria.
Side effects of Crixan 125 Suspension 30 ml
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Crixan 125 mg Suspension can be administered with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.
  • Shake well before use.

How Crixan 125 mg Suspension Works

Crixan 125 mg Suspension contains clarithromycin, which works by targeting the vital processes that bacteria need to survive. It binds specifically to the protein-making machinery inside bacterial cells, preventing them from producing the essential proteins they need to grow and multiply. Without the ability to make these proteins, the bacteria cannot reproduce and gradually die, allowing your child's natural immune system to eliminate the remaining infection from the body.
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Crixan 125 mg Suspension can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

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Heart

Caution

Crixan 125 mg Suspension should be used with caution in children who have heart conditions and only if prescribed by a doctor. Therefore, please consult your healthcare provider before administering Crixan 125 mg Suspension.

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Geriatrics

Not applicable

Crixan 125 mg Suspension is for paediatric patients only.

What if I have taken an overdose of Crixan 125 mg Suspension

If your child accidentally takes too much of this medicine, they may experience severe vomiting, stomach pain, or severe diarrhoea. Seek immediate medical attention.

Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Crixan 125 mg Suspension to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child is sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses, and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Crixan 125 mg Suspension.
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How Soon It Starts Working

The time required for Crixan 125 mg Suspension to start to work: Crixan 125 mg Suspension ideally shows its action within 30 to 60 minutes after administration.

The time for which the effects of Crixan 125 mg Suspension last: The effect of Crixan 125 mg Suspension lasts for 8 hours.

What if you forget to take Crixan 125 mg Suspension

If you forget to give a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular schedule. Do not give a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Crixan 125 mg Suspension out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check the liquid before giving: Always look at the liquid suspension before measuring a dose to ensure there is no discolouration or unusual clumping.
  • Never skip shaking the bottle: Shaking the bottle thoroughly before every single dose is crucial; otherwise, your child may receive too little medicine at the start and too much at the bottom of the bottle.
  • Do not save leftovers for later: Safely discard any leftover liquid after the prescribed course is complete. Never use leftover medicine to treat a future illness, as expired liquid antibiotics can lose potency or become harmful.
  • Watch for severe gut issues: If your child develops persistent, watery diarrhoea during or up to a few weeks after treatment, contact your doctor immediately instead of giving over-the-counter anti-diarrhoea medicines.
  • Monitor for early allergic reactions: Keep a close eye on your child during the first few days of starting Crixan 125 mg Suspension for any signs of rash, hives, or swelling.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain specific allergy medicines (such as older non-sedating antihistamines like terfenadine or astemizole): May increase the risk of serious, irregular heart rhythms when taken at the same time. Common daily antihistamines (like cetirizine or loratadine) typically do not carry this same risk.
  • Stomach acid reducers or motility drugs: Can change how the antibiotic is absorbed or alter the safety of your child's heart rhythm.
  • Other antibiotics: Using this medicine alongside certain other bacterial treatments may reduce its overall effectiveness.
ClarithromycinMethylergometrine
Critical
ClarithromycinQuinidine
Critical

Drug-Drug Interactions

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ClarithromycinMethylergometrine
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Methylergometrine is taken with Crixan 125 Suspension 30 ml, the amount of Methylergometrine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Methylergometrine is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinQuinidine
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Quinidine is taken with Crixan 125 Suspension 30 ml, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinSaquinavir
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Crixan 125 Suspension 30 ml is taken with Saquinavir, increases the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Saquinavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinConivaptan
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Crixan 125 Suspension 30 ml is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinFlibanserin
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Flibanserin is taken with Crixan 125 Suspension 30 ml, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinSilodosin
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
Taking Silodosin with Crixan 125 Suspension 30 ml may significantly increase the blood levels and effects of Silodosin, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Silodosin is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not stop using any medications without a doctor's advice.
ClarithromycinDronedarone
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Dronedarone is taken with Crixan 125 Suspension 30 ml, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinVenetoclax
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Venetoclax is taken with Crixan 125 Suspension 30 ml, the body's ability to break down Venetoclax may be reduced.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Venetoclax is not recommended, please consult your doctor before taking it.
ClarithromycinDroperidol
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
Co-administration of Droperidol with Crixan 125 Suspension 30 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinNimodipine
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Nimodipine is taken with Crixan 125 Suspension 30 ml, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Can interfere with how your child's liver processes this medicine, leading to higher levels of the drug in the body and increasing the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Crixan 125 mg Suspension is used to treat bacterial infections.
Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.
Crixan 125 mg Suspension treats only bacterial infections. It will not work for viral infections such as the common cold or flu.
No, Crixan 125 mg Suspension is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.
Yes, Crixan 125 mg Suspension can be taken with or without food. Giving the suspension with food or a glass of milk can actually help prevent stomach upset if your child has a sensitive tummy. Talk to your doctor if your child experiences frequent nausea.
If your child vomits shortly after taking a dose, do not automatically give a second dose right away. Contact your doctor or pharmacist immediately for guidance on whether to repeat the dose, as the correct action depends on the exact timing and your child's specific situation.
Yes, mild diarrhoea is a common side effect of antibiotics as they temporarily alter the natural bacteria in the gut. However, if the diarrhoea becomes watery, severe, or contains blood, stop giving the medicine immediately. Talk to your doctor right away in these cases.
Storage requirements depend on the specific brand and formulation. Some must be refrigerated, while others can be kept at room temperature, but they must never be frozen. Read the packaging label carefully or talk to your pharmacist to be sure.
It is highly recommended not to mix the medicine into a large bottle of milk or juice, because if your child does not finish the entire drink, they will not receive their full dose. Always give the measured dose directly. Talk to your doctor or pharmacist if your child struggles to swallow the liquid.
Give the missed dose as soon as you remember. If it is almost time for the next scheduled dose, skip the missed one and return to your normal routine. Never double the dose. Talk to your doctor or pharmacist if you miss more than one dose.
Some over-the-counter allergy, cold, or cough preparations can interact poorly with this antibiotic. Always check with a healthcare professional before combining any other medicines with this prescription. Talk to your doctor or pharmacist for safe recommendations.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - CRI0006
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