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compositionComposition:ACETAMINOPHEN-125MG
prescription
Prescription Medicine
info
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CRUXOL 125MG SYRUP is used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headaches, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains. It contains Acetaminophen, which works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and inflammation. Also, it affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby it reduces fever. In some cases, it may cause side effects such as nausea, stomach pain and dark-coloured urine. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACETAMINOPHEN-125MG

Manufacturer/Marketer :

Atlanta Biotec

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About CRUXOL 125MG SYRUP

CRUXOL 125MG SYRUP is a widely used pain reliever and fever reducer. Most people tolerate this medicine very well, although some may experience mild side effects such as nausea or a mild feeling of weakness. If you develop serious symptoms, such as a severe skin rash, yellowing of your eyes or skin, or dark urine, stop taking the medication and consult your doctor immediately.

Before using this medicine, talk to your doctor if you have a history of liver disease, kidney problems, or if you regularly consume alcohol. Do not take this if you have a known severe allergy to this medication or any of its ingredients, as this can lead to serious complications.

CRUXOL 125MG SYRUP is the active ingredient found in many commonly used brands, including products such as Crocin, Dolo 650, Calpol, and Tylenol. Always check medicine labels carefully, as taking more than one product containing CRUXOL 125MG SYRUP can lead to accidental overdose.

Avoid taking other medications containing the same active ingredient or drinking alcohol while on this treatment, as this significantly increases the risk of liver damage. If you are pregnant, breastfeeding, elderly, or have chronic medical conditions, consult your healthcare provider to ensure this medication is safe for your specific needs.

Uses of CRUXOL 125MG SYRUP

CRUXOL 125MG SYRUP is commonly used to relieve pain and reduce fever associated with a variety of everyday illnesses and conditions. It helps improve comfort and supports recovery by effectively managing these common symptoms. 

  • Mild to moderate pain: CRUXOL 125MG SYRUP helps relieve everyday body aches, headaches, toothaches, and menstrual cramps by raising the body's overall pain threshold.
  • Fever: This medication works on the heat-regulating center of the brain to lower high body temperatures associated with colds, flu, or infections.

Key Benefits

This medication offers reliable, targeted relief that helps you manage temporary discomfort so you can maintain your daily routine. By easing physical discomfort, it supports better rest and a more comfortable recovery process.

Key benefits include:

  • Rapid pain relief: It starts working quickly to ease discomfort, allowing for easier movement and improved comfort during recovery.
  • Effective temperature control: By lowering fevers, it helps reduce chills, sweating, and the general feeling of being unwell that often accompanies infections.
  • Gentle on the stomach: Unlike many nonsteroidal anti-inflammatory drugs (NSAIDs), CRUXOL 125MG SYRUP is less likely to irritate the stomach lining and does not carry the same risk of stomach ulcers when used as directed.
  • Does not affect blood clotting like NSAIDs: CRUXOL 125MG SYRUP does not significantly interfere with platelet function, making it a suitable option for many people who cannot tolerate NSAIDs, although medical advice may still be needed in certain situations.
Side effects of Cruxol 125mg Syrup 60ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get urgent medical help if you notice abnormal lung sounds with symptoms, like bluish skin, flare-ups of your nostrils, or trouble breathing.
  • If you have asthma or allergies, managing these conditions with inhalers and bronchodilators can help prevent abnormal lung sounds.
  • Infections may need antibiotics or breathing therapy to help open your airways and make breathing easier.
  • Wash your hands regularly and take other steps to avoid getting sick and spreading germs.
  • Doing breathing exercises can help improve your lung function and make breathing easier.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.

Directions for Use

To get the best and safest results from this medication, please follow these step-by-step instructions:

  • Take the tablet by mouth, swallowing it whole with a full glass of water.
  • Do not crush, chew, or break the tablet unless specifically advised by your doctor or pharmacist.
  • You may take this medication with or without food. If you experience mild stomach upset, taking it with a meal can help.
  • Always use the measuring device provided with the product if you are taking a liquid form, rather than a regular household spoon.

Always follow your doctor's exact instructions regarding how and when to take this medicine. Do not take more than the recommended amount within a 24-hour period.

How CRUXOL 125MG SYRUP Works

CRUXOL 125MG SYRUP works mainly in the central nervous system to relieve pain and reduce fever. Its exact mechanism is not fully understood, but it is thought to act through multiple pathways in the brain, including mild reduction of pain-causing chemical signals and involvement of brain pathways that regulate how pain is perceived. Unlike anti-inflammatory painkillers, it has only weak activity in reducing inflammation. To reduce fever, the medication acts on the hypothalamus (the part of the brain that controls body temperature). It lowers the body’s temperature “set point” in the brain’s temperature control centre (hypothalamus), which then triggers heat loss through sweating and increased blood flow to the skin. This dual action provides effective, temporary relief from both physical pain and elevated body temperatures.
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Alcohol

Unsafe

Alcohol should not be consumed with CRUXOL 125MG SYRUP as it may damage your liver and lead to excessive drowsiness or dizziness.

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Pregnancy

Consult your doctor

Please consult a doctor if you are pregnant or planning for pregnancy before using CRUXOL 125MG SYRUP. Your doctor may recommend the lowest dose of CRUXOL 125MG SYRUP and for the shortest duration if you are pregnant.

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Breast Feeding

Consult your doctor

Only consume CRUXOL 125MG SYRUP, if you are recommended by a doctor.

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Driving

Safe if suggested

Can be safely taken, CRUXOL 125MG SYRUP usually does not affect driving ability.

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Liver

Caution

CRUXOL 125MG SYRUP to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

CRUXOL 125MG SYRUP to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Consult your doctor

CRUXOL 125MG SYRUP can be given safely to children provided a child specialist has recommended the dose.

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Heart

Safe if suggested

CRUXOL 125MG SYRUP is safe for use in heart patients if recommended by the physician.

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Geriatrics

Safe if suggested

CRUXOL 125MG SYRUP is safe for use in elderly patients if recommended by the physician.

What if I have taken an overdose of CRUXOL 125MG SYRUP

An overdose of this medication can cause severe, life-threatening liver damage. If you suspect you or someone else has taken too much of this medicine, seek immediate medical attention or call a poison control center right away, even if there are no immediate symptoms. Early medical intervention is critical to prevent serious complications.

Diet & Lifestyle Advise

  • Strictly limit alcohol consumption: Avoid drinking alcohol while using this medicine, as combining the two significantly increases the strain on your liver and elevates the risk of liver damage.
  • Stay hydrated: Drink plenty of water and clear fluids, especially if you are taking this medication to reduce a fever, to help prevent dehydration.
  • Prioritise physical rest: Give your body ample time to rest and heal, particularly when dealing with acute pain, muscle strains, or feverish illnesses.
  • Track your other medications: Carefully read the labels of all over-the-counter cough, cold, sinus, or allergy products you are taking to ensure they do not also contain this same active ingredient, avoiding accidental double-dosing.
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How Soon It Starts Working

The time required for CRUXOL 125MG SYRUP to start to work: CRUXOL 125MG SYRUP ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of CRUXOL 125MG SYRUP last: The effect of CRUXOL 125MG SYRUP lasts for 4 to 6 hours.

What if you forget to take CRUXOL 125MG SYRUP

Since this medication is often taken only as needed, you may not be on a fixed schedule. If you are taking it regularly and miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular timing. Do not take a double dose to make up for a missed one.

Storage

• Store CRUXOL 125MG SYRUP tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medicine in its original container with the lid tightly closed.

Drug Warnings

  • Check other product labels: Look for the active ingredients in any other pain, cold, or sinus medications you are using to ensure they do not overlap with CRUXOL 125MG SYRUP.
  • Inspect the medication: Before taking, inspect the tablet or liquid. Do not use if the tablet is broken, crumbly, or if the liquid form has changed color, looks cloudy, or contains unusual particles.
  • Use precise measuring tools: If using a liquid form of CRUXOL 125MG SYRUP, always use the syringe or measuring cup provided with the package. Never use a standard kitchen spoon, which can lead to inaccurate dosing.
  • Monitor your symptoms: If your fever lasts more than three days or your pain persists for more than ten days (or five days for children), stop taking the medicine and consult your doctor.
  • Watch for skin reactions: In very rare cases, this medication can cause severe skin reactions. Stop use and seek immediate medical care if you develop skin reddening, blisters, or a rash.

Drug-Drug Interactions

verifiedApollotooltip

Certain medicines can affect the safety or effectiveness of CRUXOL 125MG SYRUP. To minimise the risk of harmful interactions, inform your doctor about all suggested medicines, over-the-counter products, vitamins, and herbal supplements you are currently taking: 

  • Warfarin (blood thinners): Regular, long-term use of CRUXOL 125MG SYRUP may increase the risk of bleeding when taken alongside blood thinners.
  • Other products containing the same active ingredient: Taking these together increases the risk of severe liver damage due to accidental overdose.
  • Certain anti-seizure medications (such as carbamazepine or phenytoin): May increase the risk of liver damage and reduce the effectiveness of CRUXOL 125MG SYRUP.
ParacetamolMipomersen
Severe
ParacetamolKetamine
Severe

Drug-Drug Interactions

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ParacetamolMipomersen
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Mipomersen with Cruxol 125mg Syrup 60ml may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Cruxol 125mg Syrup 60ml and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of ketamine and Cruxol 125mg Syrup 60ml may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Cruxol 125mg Syrup 60ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolOxazepam
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Cruxol 125mg Syrup 60ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Lomitapide and Cruxol 125mg Syrup 60ml may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Teriflunomide with Cruxol 125mg Syrup 60ml may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Cruxol 125mg Syrup 60ml with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Some foods and beverages may increase the risk of side effects or affect how CRUXOL 125MG SYRUP works. Follow your healthcare provider’s advice regarding dietary precautions while using this medicine: 

  • Alcohol: Consuming alcohol while taking this medication significantly increases the risk of severe liver damage.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

CRUXOL 125MG SYRUP is used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headaches, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains.
CRUXOL 125MG SYRUP works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, CRUXOL 125MG SYRUP affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.
You are not recommended to take CRUXOL 125MG SYRUP with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
CRUXOL 125MG SYRUP may affect how certain tests work such as blood sugar test and uric acid test. Therefore, if you are about to undergo blood test or any laboratory tests, inform your doctor or lab technician that you are taking CRUXOL 125MG SYRUP.
No. Do not take CRUXOL 125MG SYRUP with other medicines that contain paracetamol, including many cold, flu, sinus, and allergy products. Doing so may lead to accidental overdose and serious liver damage. Always check the ingredient list and consult your doctor or pharmacist if unsure.
If you take more than recommended doses of CRUXOL 125MG SYRUP, it may cause overdose and lead to serious liver damage. The symptoms of overdose include vomiting, loss of appetite, stomach pain, paleness and nausea. However, if you notice any of these symptoms while taking CRUXOL 125MG SYRUP, please consult a doctor immediately.
Yes, excessive intake or prolonged intake of CRUXOL 125MG SYRUP can damage your liver. Do not exceed a daily dose of more than 4 gm.
To ensure safe usage of CRUXOL 125MG SYRUP, follow these simple steps. Take the recommended dose, never take an overdose, and inform your doctor if you become pregnant while using this medication. Monitor your body's response and report any side effects. Also, avoid consuming alcohol while taking this medication. By following these guidelines, you'll maximize the benefits of CRUXOL 125MG SYRUP and protect your health.
CRUXOL 125MG SYRUP provides temporary relief from headaches, but it doesn't address the underlying cause. Your doctor will help identify the underlying issue and recommend targeted treatment for effective and lasting relief.
CRUXOL 125MG SYRUP can relieve cold-related symptoms such as sore throat, headache, earache, and lower fever. Remember, CRUXOL 125MG SYRUP is only meant to help manage symptoms, not cure the underlying illness.
If you vomit after taking CRUXOL 125MG SYRUP, don't panic. Simply take your next dose and continue with your regular schedule. Try to observe whether the tablet or another reason caused the vomiting. If you vomit again after the next dose, stop taking the medication and consult your doctor to determine the cause and find appropriate management.
Take CRUXOL 125MG SYRUP every 6-8 hours as needed to relieve fever and pain. However, do not take it for more than 3 days. If your symptoms persist or worsen, stop taking CRUXOL 125MG SYRUP and consult a doctor for proper treatment.
Some babies may become sleepy or relaxed after taking CRUXOL 125MG SYRUP (the recommended dose as directed by the doctor), while others won't. Monitor your baby's behavior and consult your pediatrician if you have any concerns or need to adjust their dosage.
CRUXOL 125MG SYRUP is generally safe for children when used correctly and in the recommended dosage. However, following the recommended dosage guidelines and consulting with a paediatrician before administering it to your child is essential. Always read the label carefully, and be aware of the risks of overdose or potential interactions with other medications.
No, CRUXOL 125MG SYRUP is not an antibiotic. It does not fight against the bacteria. It is a pain reliever and fever reducer commonly used to treat mild to moderate pain and reduce fever.
You can take CRUXOL 125MG SYRUP and ibuprofen together under the guidance of a doctor. There is no known drug interaction between them, but both medications work to relieve pain. It's essential to consult a doctor to find the best medication that suits your health status and avoid any potential complications.
The working of CRUXOL 125MG SYRUP for you may vary based on factors such as the dose, the severity of your condition, and how your body responds to the medication. Generally, when taken orally, CRUXOL 125MG SYRUP typically starts working within 15 to 30 minutes. You may begin to feel relief from pain and fever shortly after taking it. Depending on the individual and the formulation used, the effects can last for about 4 to 8 hours.
CRUXOL 125MG SYRUP in rare cases may cause nausea and vomiting in some individuals as it is reported as a common side effect. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
CRUXOL 125MG SYRUP is not typically used to relieve stomach pain due to indigestion. It is more effective for pain relief and fever reduction. For indigestion-related stomach pain, antacids or other medications specifically designed to treat indigestion might be more appropriate. It's best to consult your doctor for the most suitable treatment.
Yes, you can take CRUXOL 125MG SYRUP with antibiotics only under a doctor's suggested. CRUXOL 125MG SYRUP may interact with the antibiotic. Dose adjustment is required to avoid negative complications. Always follow the doctor's advice for appropriate treatment.
The common side effects of the CRUXOL 125MG SYRUP are nausea, stomach pain, and dark-colored urine. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Yes, you can take CRUXOL 125MG SYRUP with or without food. Taking it on an empty stomach may help it work slightly faster. However, if you experience any mild stomach upset, taking it with a small meal or a glass of milk can help. Talk to your doctor if you have persistent stomach issues.
CRUXOL 125MG SYRUP is generally intended for short-term relief of temporary pain or fever. Taking this medication daily over a long period without medical supervision can increase the risk of serious side effects, particularly liver damage. If you suffer from chronic pain, talk to your doctor.
No, you should avoid drinking alcohol while taking CRUXOL 125MG SYRUP. Both alcohol and this medication are processed by your liver, and combining them significantly increases the risk of severe liver damage. For advice on managing your pain safely, talk to your doctor.
Seek emergency medical care or contact a poison control center immediately, even if your child does not show any signs of illness or distress. Overdose symptoms can take hours to appear but can cause severe, permanent liver damage if not treated quickly. Talk to your doctor or seek emergency help right away.
If you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor before taking CRUXOL 125MG SYRUP. While it has historically been considered one of the preferred options for pain and fever relief during pregnancy, more recent research has raised questions about the possible effects of prolonged prenatal exposure. For this reason, it should only be used when clearly needed, at the lowest effective dose, and for the shortest possible duration under medical guidance. Your healthcare provider can help determine whether it is appropriate for your situation.
CRUXOL 125MG SYRUP is generally considered a safer alternative than many NSAIDs for people with high blood pressure because it does not typically cause the same degree of fluid retention, stomach irritation, or blood pressure elevation. However, some studies suggest that long-term or high-dose use may have modest effects on blood pressure in certain individuals. Use the medicine exactly as directed and consult your doctor if you require frequent or prolonged use.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No. 24,Road No. 7,Shaktinagar, L.B. Nagar,Hyderabad-500 074,ANDHRA PRADESH,INDIA
Other Info - CRU0018

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