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compositionComposition:CYCLOSPORINE-100MG
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Prescription Medicine
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Cyclopyurin 100 Capsule 10's is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Prevego Healthcare & Research Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cyclopyurin 100 Capsule 10's

Cyclopyurin 100 Capsule 10's belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Cyclopyurin 100 Capsule 10's contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.

Cyclopyurin 100 Capsule 10's may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

To treat your condition effectually, continue taking Cyclopyurin 100 Capsule 10's for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.

Uses of Cyclopyurin 100 Capsule 10's

Cyclopyurin 100 Capsule 10's is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Cyclopyurin 100 Capsule 10's are as follows:

  • Treatment of Organ Transplant Rejection: Cyclopyurin 100 Capsule 10's is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
  • Treatment of Psoriasis: Cyclopyurin 100 Capsule 10's is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
  • Treatment of Rheumatoid Arthritis: Cyclopyurin 100 Capsule 10's is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

Key Benefits

  • Cyclopyurin 100 Capsule 10's suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
  • It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
  • Cyclopyurin 100 Capsule 10's helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
  • It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
  • This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
  • It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
  • Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
  • It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.

Directions for Use

  • Cyclopyurin 100 Capsule 10's can be taken with or without food. However, avoid taking it with grapefruit, pineapple, or papaya juice, as they may increase the amount of this medication in your blood.
  • It is usually taken 2 times a day or as prescribed by your doctor.
  • Swallow the whole capsule with a glass of water.
  • Do not crush, chew, or open it.

How Cyclopyurin 100 Capsule 10's Works

Cyclopyurin 100 Capsule 10's contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Cyclopyurin 100 Capsule 10's. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

It is not known whether Cyclopyurin 100 Capsule 10's will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

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Breast Feeding

Unsafe

It is not recommended to take Cyclopyurin 100 Capsule 10's while you are breastfeeding. Cyclopyurin 100 Capsule 10's passes into breast milk.

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Driving

Caution

Drive or operate machinery only if you are alert.

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Liver

Caution

Take Cyclopyurin 100 Capsule 10's only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Cyclopyurin 100 Capsule 10's.

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Children

Unsafe

Cyclopyurin 100 Capsule 10's should not be given to children, as the efficacy and safety have not been established.

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Heart

Caution

Please consult your doctor if you have a history of heart disease before taking Cyclopyurin 100 Capsule 10's. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Cyclopyurin 100 Capsule 10's should be given with caution in elderly patients due to an increased risk of side effects. Talk to your doctor if you have any concerns.

What if I have taken an overdose of Cyclopyurin 100 Capsule 10's

Take Cyclopyurin 100 Capsule 10's only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, and liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, would be helpful.
  • Practising yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy by applying a cold or hot compress to the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.
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How Soon It Starts Working

The time required for Cyclopyurin 100 Capsule 10's to start to work: The exact onset time of Cyclopyurin 100 Capsule 10's has not been clinically established.

The time for which the effects of Cyclopyurin 100 Capsule 10's last: The duration of Cyclopyurin 100 Capsule 10's’s effect is clinically not established.

What if you forget to take Cyclopyurin 100 Capsule 10's

If you miss a dose of Cyclopyurin 100 Capsule 10's, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cyclopyurin 100 Capsule 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Cyclopyurin 100 Capsule 10's if you are allergic to any of the components.
  • Let your doctor know before using Cyclopyurin 100 Capsule 10's if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
  • Cyclopyurin 100 Capsule 10's may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
  • Before taking Cyclopyurin 100 Capsule 10's, inform your doctor if you have any type of cancer.
  • Consult your doctor before taking Cyclopyurin 100 Capsule 10's if you are pregnant or planning for pregnancy.
  • Cyclopyurin 100 Capsule 10's should not be taken by breastfeeding mothers as it passes into breast milk.
  • Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Drug Interaction: Cyclopyurin 100 Capsule 10's may have interaction with other immunosuppressant medicines (tacrolimus), anti-gout (thiopurine), water pills/diuretics (amiloride, spironolactone), blood pressure-lowering pills (aliskiren), cholesterol-lowering pills (atorvastatin, pitavastatin, simvastatin). antibiotics (such as erythromycin or azithromycin), antifungals (voriconazole, itraconazole), medicines used for heart problems or high blood pressure (diltiazem, verapamil, amiodarone), used to treat menstrual problems (danazol), medicines used to treat gout (allopurinol), used to treat hepatitis C (colchicine, telaprevir).

Drug-Food Interaction: Avoid grapefruit or grapefruit juice while taking Cyclopyurin 100 Capsule 10's.

Drug-Disease Interaction: Inform your doctor if you have high blood pressure, liver or kidney disease.

CiclosporinPitavastatin
Critical
CiclosporinBosentan
Critical

Drug-Drug Interactions

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CiclosporinPitavastatin
Critical
How does the drug interact with Cyclopyurin 100 Capsule:
Coadministration of pitavastatin with Cyclopyurin 100 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Cyclopyurin 100 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinBosentan
Critical
How does the drug interact with Cyclopyurin 100 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Cyclopyurin 100 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinSimvastatin
Critical
How does the drug interact with Cyclopyurin 100 Capsule:
Combining Cyclopyurin 100 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Cyclopyurin 100 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Cyclopyurin 100 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Cyclopyurin 100 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Cyclopyurin 100 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclopyurin 100 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinSaquinavir
Severe
How does the drug interact with Cyclopyurin 100 Capsule:
Taking Cyclopyurin 100 Capsule with saquinavir may increase the blood levels and effects of Cyclopyurin 100 Capsule.

How to manage the interaction:
Taking saquinavir with Cyclopyurin 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of nausea, vomiting, diarrhea, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinSpironolactone
Severe
How does the drug interact with Cyclopyurin 100 Capsule:
Taking spironolactone with Cyclopyurin 100 Capsule may increase potassium levels in the blood.

How to manage the interaction:
Although taking spironolactone and Cyclopyurin 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience slow, fast, or uneven heartbeat, rapid breathing, numbness or tingly feeling, and muscle pain or weakness. Do not stop using any medications without consulting a doctor.
CiclosporinLercanidipine
Severe
How does the drug interact with Cyclopyurin 100 Capsule:
Using lercanidipine can make cyclosporine more effective at suppressing the immune system.

How to manage the interaction:
Co-administration of Cyclopyurin 100 Capsule with lercanidipine can possibly result in an interaction, but it can be taken if your doctor has advised it. Avoid taking cyclosporine along with other medications that suppress your immune system. It is important to watch out for any signs of infection and contact your doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, weight loss, or pain during urination. Do not stop using any medications without first talking to your doctor.
CiclosporinMorphine
Severe
How does the drug interact with Cyclopyurin 100 Capsule:
Co-administration of morphine with Cyclopyurin 100 Capsule can increase the blood levels and side effects of morphine.

How to manage the interaction:
Taking morphine with Cyclopyurin 100 Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not stop using any medications without consulting a doctor.
CiclosporinTriamterene
Severe
How does the drug interact with Cyclopyurin 100 Capsule:
Taking Triamterene with Cyclosporine can increase the risk of hyperkalemia(high levels of potassium in blood).

How to manage the interaction:
Taking Cyclopyurin 100 Capsule with Triamterene together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience slow, fast, or uneven heartbeat, rapid breathing, numbness or tingly feeling, and muscle pain or weakness contact your doctor right away. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Cyclopyurin 100 Capsule 10's belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.
Cyclopyurin 100 Capsule 10's acts as an immunosuppressant, which helps reduce pain and inflammation in the joints and prevent joint stiffness, thereby relieving rheumatoid arthritis.
If you miss a dose of Cyclopyurin 100 Capsule 10's, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.
Diarrhoea might be a side-effect of Cyclopyurin 100 Capsule 10's. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, using Cyclopyurin 100 Capsule 10's may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.
Cyclopyurin 100 Capsule 10's is known to decrease the immune system. As a result, it increases your risk of developing certain types of cancer, especially skin cancer. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.
No, Cyclopyurin 100 Capsule 10's is not a steroid. It is an immunosuppressant.
Yes, cyclosporine can cause weight gain. However, this is not a common side effect, and the amount of weight gain varies from person to person.
Yes, fatigue is a common side effect of cyclosporine. Many people who take cyclosporine report feeling tired or fatigued.
Cyclopyurin 100 Capsule 10's is an immunosuppressant medication, meaning it weakens your immune system. This can make you more susceptible to infections and other health problems. Your doctor will likely order regular blood tests to monitor your health and ensure the medication is working effectively.
Cyclopyurin 100 Capsule 10's has not been definitively linked to causing cancer. However, discussing any concerns you may have with your doctor is essential. They can provide personalized information about your health situation and why you take cyclosporine.
Common side effects of Cyclopyurin 100 Capsule 10's may include headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Cyclopyurin 100 Capsule 10's ideally should be given 12 hours apart. The capsules should be taken with water and swallowed whole. Grapefruit and grapefruit juice should be avoided, as they can increase ciclosporin levels in the blood.
The duration of Cyclopyurin 100 Capsule 10's treatment varies depending on the underlying condition and individual response.
Always consult with your doctor or pharmacist before starting any new medications or supplements while taking Cyclopyurin 100 Capsule 10's. They can help you identify potential interactions and recommend safe alternatives if necessary.
Yes, you can travel while taking cyclosporine. However, it's essential to plan and take necessary precautions. Ensure you have a sufficient supply of your medication, and be aware of any potential customs regulations or travel restrictions.
Generally, moderate exercise is safe while taking Cyclopyurin 100 Capsule 10's. However, listening to your body and avoiding overexertion is essential, especially if you have any underlying health conditions.
Excessive alcohol consumption can increase the risk of side effects and interact with cyclosporine. It's best to limit alcohol intake or avoid it altogether while taking this medication.
Your doctor will determine the frequency of your blood tests based on your situation. However, regular monitoring is essential to ensure that cyclosporine works effectively and detects potential side effects.
If you miss a dose of Cyclopyurin 100 Capsule 10's, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Some people may experience mood changes or anxiety while taking Cyclopyurin 100 Capsule 10's. If you notice any changes in your mental health, it's important to talk to your doctor.
Cyclopyurin 100 Capsule 10's occasionally causes blurred vision or eye irritation. If you experience any vision problems, contact your doctor.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Taking more than the recommended dosage does not provide additional benefit and can increase the risk of adverse effects.
Cyclopyurin 100 Capsule 10's contains cyclosporine, an immunosuppressant.
Cyclopyurin 100 Capsule 10's should not be given to children, as the efficacy and safety have not been established.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 050715S035,050716S038Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Mayo Clinic Staff. Drg 20075815 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A601207 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Cyclosporine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Pil.5300 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  7. RESTASIS® (cyclosporine ophthalmic emulsion) 0.05% [Internet]. [Accessed on 27 Feb 2025]Check here

Country of origin

India

Manufacturer/Marketer address

street,Seethammadhara,Visakhapatanam-530013
Other Info - CYC0234
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