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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cytodrox Capsule is used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). It works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks. It may cause side effects such as loss of appetite (feeling unwell and stomach upset), increased bleeding tendency, nausea, upset stomach, vomiting.
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Whats That

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Synonym :

HYDROXYCARBAMIDE

Composition :

HYDROXYUREA-500MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Cytodrox Capsule

Cytodrox Capsule belongs to a group of classes known as an antimetabolite. It is an anticancer medicine used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). Head and neck cancer is a disease including abnormal growth of the tissues of the neck and head that may also have the ability to attack or spread to other portions of the body. Sickle cell anemia is a disease in which your body results in abnormally shaped red blood cells. The cells are shaped like a curved or sickle.

In cancer, Cytodrox Capsule works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

Take Cytodrox Capsule as prescribed by your doctor. You are advised to take Cytodrox Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience loss of appetite (feeling unwell and stomach upset), Increased bleeding tendency, nausea, upset stomach, vomiting. Most of these side effects of Cytodrox Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Cytodrox Capsule , please inform your doctor if you have any allergy, kidney disease, liver disease, injury on your legs, HIV or AIDS, high level of uric acid in your blood, and treatment with chemotherapy or radiation. Cytodrox Capsule may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Cytodrox Capsule can cause harmful effects on the unborn baby. Both women and men using this Cytodrox Capsule should use birth control to avoid pregnancy. The use of this Cytodrox Capsule by either parent may results in birth defects. You should not take this Cytodrox Capsule during breastfeeding, inform your doctor if you take Cytodrox Capsule .

Uses of Cytodrox Capsule

Treatment of Head and neck cancer and sickle cell anemia (blocking flow of blood that causes pain and organ damage).

Directions for Use

• Take Cytodrox Capsule with or without food as advised by your doctor.• Cytodrox Capsule is generally taken once a day or as directed by the doctor.• Swallow Cytodrox Capsule as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Cytodrox Capsule belongs to a group of the class known as an antimetabolite. It is used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). In cancer, Cytodrox Capsule works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

How Cytodrox Capsule Works

Cytodrox Capsule works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

Storage

Keep this medicine out of the sight and reach of children.

What if I have taken an overdose of Cytodrox Capsule

Do not take more than the prescribed dose of Cytodrox Capsule as it may cause overdose. The symptoms of overdose include darkening of the skin, sores in the mouth and throat and pain, redness, swelling, and scaling on the hands and feet. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking Cytodrox Capsule inform your doctor if you have any kind of infection because Cytodrox Capsule may worsen the infections. Talk to your doctor if you have any allergy symptoms. Kidney disease, liver disease, injury on your legs, HIV or AIDS, high level of uric acid in your blood, and treatment with chemotherapy or radiation inform your doctor. Cytodrox Capsule may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Cytodrox Capsule can cause harmful effects on the unborn baby. Both women and men using this Cytodrox Capsule should use birth control to avoid pregnancy. The use of this Cytodrox Capsule by either parent may result in birth defects. You should not take this Cytodrox Capsule during breastfeeding, inform your doctor if you take Cytodrox Capsule . If any powder from a damaged pill is leaked, wash it up at once with a wet paper towel and throw the towel away in a closed plastic bag where children cannot get to it.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used with Adalimumab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cytodrox Capsule:
Taking Bupivacaine and Cytodrox Capsule may cause methemoglobinemia (a rare disorder in which the iron in the hemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately).

How to manage the interaction:
Although taking Cytodrox Capsule and bupivacaine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cytodrox Capsule:
Taking lidocaine with Cytodrox Capsule can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Cytodrox Capsule and lidocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used in conjunction with bacitracin may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with bacitracin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideVoclosporin
Severe
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used with voclosporin may raise the risk of severe infections, some kinds of cancer, including skin cancer and cancer of the lymph glands (lymphoma).

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with voclosporin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cytodrox Capsule:
Chloroprocaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Cytodrox Capsule, which may lead to methemoglobinemia.

How to manage the interaction:
Although taking Cytodrox Capsule and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used in conjunction with etanercept may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cytodrox Capsule:
Cytodrox Capsule when used with tofacitinib may raise the risk of severe infections, cancers.

How to manage the interaction:
There may be a possibility of interaction between Cytodrox Capsule with tofacitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Cytodrox Capsule:
Prilocaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Cytodrox Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Cytodrox Capsule and Prilocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Cytodrox Capsule:
Procaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Cytodrox Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Cytodrox Capsule and procaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take Cytodrox Capsule at the same time daily, either with or without a meal.
  • It is recommended to remain hydrated and drink a lot of fluids while taking Cytodrox Capsule .
  • Do not miss any dose and finish the course as recommended by your doctor.
  • Use an efficient method of birth control to prevent pregnancy while taking this Cytodrox Capsule .
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, blood cell count in your blood.

Habit Forming

No

Therapeutic Class

ANTIMETABOLITES
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Alcohol

Caution

The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of Cytodrox Capsule . If taking alcohol more amount then it causes dizziness.

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Pregnancy

Unsafe

Cytodrox Capsule is not safe during pregnancy because it may cause harmful effects to the baby.

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Breast Feeding

Caution

It is unknown whether Cytodrox Capsule is excreted in human milk. Please consult a doctor before using Cytodrox Capsule while breastfeeding.

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Driving

Caution

Cytodrox Capsule may cause dizziness or severe headache. Therefore, drive only if you alert after taking Cytodrox Capsule .

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Liver

Caution

If you have any concerns regarding the use of Cytodrox Capsule in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Cytodrox Capsule in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Safety and efficacy of Cytodrox Capsule have not established for children. Therefore not recommended for children.

Have a query?

FAQs

Cytodrox Capsule is used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage).

Take the Cytodrox Capsule as soon as you can but avoid the missed dose if it is nearly time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of Cytodrox Capsule entirely.

Immediately go to the emergency department of your nearest hospital. Be ready to tell or show what was taken, how much, and when it happened.

Cytodrox Capsule may cause a risk of skin cancer. Avoid contact with sunlight or tanning beds. Wear protective cloth and use sunscreen (SPF 30 or higher) when you are outside. Do not handle Cytodrox Capsule without the protection of skin.

Cytodrox Capsule can cause dizziness and drowsiness during the first limited hours after you take it. These side effects are more expected to happen when you start taking Cytodrox Capsule or when your doctor increases your dose.

Do not stop taking Cytodrox Capsule without discussing it with your doctor. Your doctor will most likely tell you to take another medicine, folic acid (a vitamin), to reduce some of the side effects of this Cytodrox Capsule . Take this Cytodrox Capsule exactly as instructed.

Cytodrox Capsule is a medication that requires careful monitoring and dosing based on your individual medical condition, weight, and other factors. Please consult your healthcare provider if you have any questions about your hydroxyurea dosage. They can provide personal guidance and ensure you're taking the correct amount.

Cytodrox Capsule can cause diarrhoea as a side effect. If you have watery or bloody diarrhoea, call your doctor. Do not use anti-diarrhea medicine unless your paediatrician tells you to.

Yes, it is recommended that you avoid certain foods and drinks while taking Cytodrox Capsule . Some substances can interact with the medication, potentially affecting its effectiveness or increasing the risk of side effects. Here are some things to avoid: alcohol, grapefruit, grapefruit juice, Foods high in tyramine (aged cheeses, cured meats, fermented foods, and certain types of beans), and excessive caffeine.

If you're feeling tired and weak while taking hydroxyurea, try these tips: rest when needed, eat healthy foods, drink plenty of water, and get enough sleep. Gentle exercise can also help. Discuss with your healthcare provider if you're experiencing severe fatigue or weakness that interferes with your daily activities. They may be able to adjust your treatment or recommend additional strategies.

Cytodrox Capsule is not safe during pregnancy because it may cause harmful effects to the baby.

Cytodrox Capsule can make your hair thin or fall out. This is a common side effect, but how much hair you lose can change from person to person. Sometimes, hair loss is temporary, but in rare cases, it can be permanent. If you're worried about hair loss, talk to your doctor. They can help you manage it.

If you notice any changes in your skin while taking Cytodrox Capsule , talk to your doctor. It's common to have darker skin or a rash. To protect your skin, use sunscreen, moisturize, and avoid things that might irritate it. If your skin problems are severe, see a dermatologist.

If you are having trouble with constipation while taking Cytodrox Capsule , try these tips: eat more fibre, drink plenty of water, exercise regularly, and consider using over-the-counter laxatives after talking to your doctor. Avoid food that can worsen constipation, and try to go to the bathroom at the same time each day. If your constipation is severe, talk to your doctor.

To reduce the risk of infection while taking Cytodrox Capsule , wash your hands often, avoid sick people, keep your home clean, get vaccinated, watch for signs of infection, and follow your doctor's instructions.

Common side effects of Cytodrox Capsule may include loss of appetite (feeling unwell and stomach upset), Increased bleeding tendency, nausea, upset stomach, and vomiting. Most of these side effects of Cytodrox Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - CYT0063

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