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compositionComposition:CHOLECALCIFEROL-600000IU
prescription
Prescription Medicine
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D3Lok-6L Injection 1 ml is used to regulate calcium and phosphate metabolism. It effectively treats various conditions in the body like Vitamin D deficiency, osteoporosis (weak and brittle bones), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). It contains Vitamin-D3 (Cholecalciferol), a fat-soluble vitamin. It helps maintain blood calcium and phosphorus levels and the mineralization of bone. It treats and prevents bone disorders, such as rickets and osteomalacia. It aids in calcium absorption, enabling bone growth and repair. It further prevents cartilage degeneration. It is also used to maintain a healthy immune system.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHOLECALCIFEROL-600000IU

Manufacturer/Marketer :

Silok Pharmaceuticals

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About D3Lok-6L Injection 1 ml

D3Lok-6L Injection 1 ml is a prescribed injection used to treat and prevent severe vitamin deficiencies, particularly when your body cannot absorb nutrients properly through food or oral supplements. It plays a critical role in helping your body absorb calcium, which is essential for maintaining strong, healthy bones and teeth. This medicine is also commonly used to manage bone-weakening conditions such as osteoporosis.

This injection is usually given on a weekly or monthly schedule, or as a single large dose, depending on your specific health needs and blood test results. Because this medication is injected directly into your body, you do not need to take it with food, though eating a diet rich in healthy fats and calcium can help maximise its overall benefits. Making simple lifestyle adjustments, such as including low-impact weight-bearing exercises in your routine, can also significantly improve your bone health results.

While D3Lok-6L Injection 1 ml is highly effective, some people may experience mild side effects, most commonly mild pain, redness, or swelling at the injection site. However, you should consult your doctor immediately if you experience serious symptoms like persistent nausea, severe constipation, confusion, or unusual muscle weakness, which could point to high calcium levels in your blood.

Do not take this if you have high calcium levels in your blood or urine, severe kidney disease, or high levels of this specific vitamin in your body. It is vital to talk to your doctor before starting this medicine if you have a history of kidney stones, heart disease, or sarcoidosis, as these conditions may require extra monitoring.

This medication can interact with other substances; for instance, certain water pills or heart medicines can alter how your body handles calcium, while heavy alcohol use can weaken your bones and reduce the benefits of this treatment. If you are pregnant, breastfeeding, or planning a pregnancy, or if you are managing health conditions as an older adult, talk to your doctor to ensure this treatment is safe for you.

Uses of D3Lok-6L Injection 1 ml

D3Lok-6L Injection 1 ml is used to treat and prevent severe vitamin deficiencies. The detailed uses of D3Lok-6L Injection 1 ml are as follows:

  • Severe Vitamin Deficiency: It quickly restores dangerously low levels of this essential bone-building nutrient when oral tablets are not effective or cannot be tolerated.
  • Osteoporosis Management: It helps maintain bone density and strength when used alongside other targeted bone-thinning treatments to prevent fractures.
  • Malabsorption Support: It provides a reliable nutrient source for individuals with digestive disorders who cannot absorb vitamins properly through their stomach or intestines.

Key Benefits

D3Lok-6L Injection 1 ml helps correct nutrient deficiency by delivering the essential nutrient directly into the body for rapid and reliable absorption. It is especially useful when absorption from the digestive tract is reduced or when a quick correction of deficiency is needed.

  • Provides Reliable Nutrient Replacement: By bypassing the digestive system, D3Lok-6L Injection 1 ml ensures that the nutrient is delivered directly into the body, making it useful for people recovering from surgery or those with conditions that affect nutrient absorption.
  • Helps Improve Bone and Muscle Health: Restoring healthy nutrient levels can help reduce bone discomfort, muscle weakness, and deficiency-related symptoms while supporting stronger movement and physical function.
  • Supports Overall Recovery and Wellbeing: Adequate nutrient levels help support immune function, energy production, and general recovery, helping you feel more active and resilient during the healing process.

Directions for Use

  • The timing and frequency of D3Lok-6L Injection 1 ml will be determined by your doctor, based on your medical condition.
  • This medication should only be administered by a qualified healthcare provider.
  • Do not attempt self-administration of the injection.
  • Follow your healthcare provider’s instructions about the medication and any steps to track your progress or precautions during treatment.

How D3Lok-6L Injection 1 ml Works

D3Lok-6L Injection 1 ml contains cholecalciferol. Once injected, D3Lok-6L Injection 1 ml enters your system and is processed by your liver and kidneys into its active form. This active form acts like a key that unlocks your body's ability to absorb calcium and phosphorus from your daily diet. Under normal circumstances, the body cannot absorb these minerals efficiently on its own. By boosting mineral absorption, this medicine ensures that there is always enough calcium circulating in your bloodstream. When blood calcium levels are stable, your body does not need to steal calcium from your bones, which helps preserve bone density, keeps your skeleton strong, and supports healthy muscle and nerve function.
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Alcohol

Caution

It is advised to avoid alcohol consumption while on treatment with D3Lok-6L Injection 1 ml to prevent any undesirable side effects.

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Pregnancy

Safe if prescribed

D3Lok-6L Injection 1 ml is considered safe to be used in pregnancy. However, let your doctor know if you are pregnant or planning pregnancy before taking D3Lok-6L Injection 1 ml. Your doctor will decide on the dose of this medicine based on your requirement.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor. Your doctor will decide the dose of D3Lok-6L Injection 1 ml based on your condition.

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Driving

Caution

D3Lok-6L Injection 1 ml usually does not interfere with your driving ability. Do not drive or operate machinery if you experience any dizziness while using D3Lok-6L Injection 1 ml. Please consult your doctor if you notice any symptoms.

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Liver

Consult your doctor

Inform your doctor if you have any pre-existing or history of liver diseases before receiving D3Lok-6L Injection 1 ml.

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Kidney

Consult your doctor

Inform your doctor if you have kidney diseases like kidney stones or undergoing dialysis before receiving D3Lok-6L Injection 1 ml.

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Children

Consult your doctor

Please consult your doctor. Your doctor will decide the appropriate dose based on your child's condition.

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Heart

Consult your doctor

Inform your doctor if you have any pre-existing or history of heart diseases before receiving D3Lok-6L Injection 1 ml.

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Geriatrics

Consult your doctor

Please consult your doctor before giving D3Lok-6L Injection 1 ml to elderly people.

What if I have taken an overdose of D3Lok-6L Injection 1 ml

If you receive too much of this medicine, or if you suspect an overdose, seek immediate emergency medical attention. Symptoms of an overdose may include severe weakness, confusion, constant vomiting, and extreme thirst.

Diet & Lifestyle Advise

  • Eat a balanced diet rich in calcium by including foods like dairy products, leafy green vegetables, and fortified foods to give the medicine the raw materials it needs to work.
  • Engage in regular, low-impact weight-bearing exercises like walking, climbing stairs, or light strength training to naturally support and build bone density.
  • Limit your alcohol intake, as excessive alcohol can weaken bone structure and make it harder for your body to process essential nutrients.
  • Avoid smoking, as tobacco use is directly linked to weaker bones and a higher risk of fractures.
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How Soon It Starts Working

The time required for D3Lok-6L Injection 1 ml to start to work: D3Lok-6L Injection 1 ml effect shows its action within 24 hours of administration. 

The time for which the effects of D3Lok-6L Injection 1 ml last: D3Lok-6L Injection 1 ml effect lasts for a few hours.

What if you forget to take D3Lok-6L Injection 1 ml

If you miss an injection appointment or forget to take your scheduled dose, contact your healthcare provider right away to get a revised dosing schedule. Do not double the dose or take an extra injection to make up for a missed one.

Storage

• Store D3Lok-6L Injection 1 ml at room temperature between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Always inspect the liquid inside the vial or ampoule before use; do not inject it if you see floating particles, cloudiness, or any discolouration.
  • Never reuse needles or syringes, and discard them immediately after use in an approved, puncture-resistant sharps disposal container.
  • Rotate your injection sites (such as the thigh or upper arm) with each dose to reduce the risk of skin irritation, pain, or tissue damage.
  • Keep all scheduled appointments for blood tests so your doctor can safely monitor your calcium and nutrient levels.
  • Never share your prescribed medication or injection equipment with anyone else, even if they have similar symptoms.

Drug-Drug Interactions

verifiedApollotooltip
  • Water pills (thiazide diuretics): Taking these alongside your injection can increase the risk of building up too much calcium in your blood.
  • Heart medicines (such as digoxin): High calcium levels caused by this injection can make you much more sensitive to these medicines, increasing the risk of serious irregular heartbeats.
  • Seizure medications (like phenytoin or phenobarbital): These drugs can speed up how your body processes the injection, making it less effective.
  • Steroid medications: These can lower your body's ability to absorb calcium, which may reduce the overall benefits of your treatment.
ColecalciferolCalcitriol
Severe
ColecalciferolAluminium hydroxide
Severe

Drug-Drug Interactions

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ColecalciferolCalcitriol
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between D3Lok-6L Injection 1 ml and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolAluminium hydroxide
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
The combined use of aluminum hydroxide with D3Lok-6L Injection 1 ml may increase the risk of toxicity.

How to manage the interaction:
Co-administration of D3Lok-6L Injection 1 ml with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ColecalciferolSucralfate
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between D3Lok-6L Injection 1 ml and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolErgocalciferol
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between D3Lok-6L Injection 1 ml and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolCalcifediol
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between D3Lok-6L Injection 1 ml and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDoxercalciferol
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between D3Lok-6L Injection 1 ml and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with D3Lok-6L Injection 1 ml:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between D3Lok-6L Injection 1 ml and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with D3Lok-6L Injection 1 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

D3Lok-6L Injection 1 ml is used to treat Vitamin D deficiency, Osteomalacia (Rickets), Osteoporosis, and Hypocalcemia (low blood calcium levels).
D3Lok-6L Injection 1 ml is a dietary supplement that consists of Cholecalciferol or Vitamin D3. It regulates calcium and phosphate metabolism and works by increasing the amount of vitamin D in the body.
D3Lok-6L Injection 1 ml is used to increase low levels of calcium in the body. Hence it is not advised to use D3Lok-6L Injection 1 ml during hypercalcaemia since it causes an overdose of calcium leading to kidney stones and other effects.
Avoid taking more than one multivitamin product concomitantly unless advised by the doctor. Taking similar nutritional supplements simultaneously can lead to a vitamin overdose or other serious side effects.
D3Lok-6L Injection 1 ml may increase the absorption of Aluminium in antacids. Hence it is advised to take D3Lok-6L Injection 1 ml two hours before or four hours after taking antacids.
Fatty fish (tuna, trout, salmon, and mackerel), fish liver oil, egg yolk, and beef liver are good sources of Vitamin D. Vitamin D-fortified foods like plant milk, dairy, juices, and breakfast cereals are also good sources of Vitamin D.
Not getting enough vitamin D through diet/food, limited exposure to sunlight, organs such as the liver or kidney not being able to convert vitamin D to its active form in the body, taking medicines which interfere with the absorption of vitamin D may cause deficiency of vitamin D.
D3Lok-6L Injection 1 ml is administered either intramuscularly or subcutaneously by a healthcare professional.
D3Lok-6L Injection 1 ml helps treat and prevent bone disorders, supports immune health, and promotes muscle and nerve functioning. It aids the absorption of calcium and makes the bones strong.
Since a doctor will administer D3Lok-6L Injection 1 ml, he/she will determine the time of administration.
People who are allergic to vitamin D, have hypervitaminosis D (high levels of vitamin D), hypercalcemia (high levels of calcium) or malabsorption syndrome should not take D3Lok-6L Injection 1 ml.
Too much vitamin D may cause hypervitaminosis D (high levels of vitamin D). However, as D3Lok-6L Injection 1 ml is administered by a doctor it is unlikely to overdose on this medicine.
The amount of Vitamin D3 needed depends on age. The average daily recommended amount as per NIH is Birth-12 months: 400IU 1-13 years: 600IU 14-18 years: 600IU 19-70 years: 600IU 71 years and older: 800IU Pregnant and breastfeeding women: 600IU
Vitamin D deficiency may cause rickets (bones become soft, weak and deformed) in children and osteomalacia (a bone disorder that causes muscle weakness and bone pain) in adults.
D3Lok-6L Injection 1 ml is injected directly into your muscle or under your skin, completely bypassing your digestive tract. This makes it a highly effective option for people who have severe deficiencies or digestive conditions that prevent them from absorbing oral tablets properly. Talk to your doctor to find out which form is best for you.
Your injection schedule depends entirely on your personal blood test results and the severity of your deficiency. Some people only need a single dose, while others may require weekly or monthly injections. Talk to your doctor for your specific schedule.
While this medicine is typically given by a healthcare professional, some patients can be trained to use it at home. Do not attempt to inject yourself until you have received proper, hands-on training from your doctor or nurse. Talk to your doctor to see if home administration is safe for you.
High calcium levels (hypercalcaemia) can cause symptoms like extreme thirst, frequent urination, nausea, vomiting, severe constipation, confusion, and unusual muscle weakness. If you notice any of these signs, contact your healthcare provider immediately. Talk to your doctor if you have any concerns.
During pregnancy and breastfeeding, your nutritional needs change, and very high doses of certain vitamins can carry risks. This medicine should only be used under the strict supervision of your doctor during these times. Talk to your doctor to determine if this treatment is safe for you and your baby.
Yes, your doctor will likely schedule periodic blood tests to check your calcium, phosphorus, and vitamin levels. This monitoring ensures that the medicine is working safely and that you are receiving the correct dose. Talk to your doctor or pharmacist about how often you need these tests.
It is highly recommended to limit or avoid alcohol during treatment. Alcohol can interfere with how your body uses nutrients and can weaken your bones over time, which reduces the benefits of your therapy. Talk to your doctor if you have questions about alcohol use.
Mild pain, redness, or swelling at the injection site is normal and usually improves in a few days. Applying a cold compress to the area can help reduce discomfort. However, if the pain gets worse, or if you notice signs of infection like pus or severe warmth, talk to your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Vitamin D3 Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Nair, Rathish, and Arun Maseeh. Vitamin D: The "sunshine" vitamin. National library of Medicine, National center for Biotechnology information. Pubmed Central. 2012 [Accessed on 21st June 2022]Check here
  5. Labialfarma. Electronics Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 21st June 2022]Check here
  6. Pil D3 Vicotrat En 2018 04. [Accessed on 02 Jun. 2026]Check here
  7. Pharma Patent Kft. Health Products Regulatory Authority (HPRA) [Revised in December 2020] [Accessed on 21st June 2022]Check here

Country of origin

India

Manufacturer/Marketer address

b/8,Ground Floor,Anjana Society, India Colony Bus Stand,Bapunagar, Ahmedabad -382350
Other Info - D3L0013

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