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compositionComposition:DABIGATRAN
prescriptionPrescription Medicine
DABXIGA 110MG CAPSULE 10'S
DABXIGA 110MG CAPSULE 10'S
DABXIGA 110MG CAPSULE 10'S

DABXIGA 110MG CAPSULE is used to prevent blood clot formation. It contains Dabigatran, which works by inhibiting the production of clotting factors and makes your blood flow easily through your veins. It may cause side effects such as bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DABIGATRAN

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About DABXIGA 110MG CAPSULE

DABXIGA 110MG CAPSULE is used to prevent blood clot formation and prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm). It is also used to prevent deep vein thrombosis (blood clots in the leg veins) and pulmonary embolism (blood clots in the lung).

DABXIGA 110MG CAPSULE contains ‘Dabigatran’, which works by inhibiting the production of clotting factor Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

In some cases, DABXIGA 110MG CAPSULE may cause certain common side effects such as bleeding, anaemia, nausea, stomach pain, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

If you are known to be allergic to DABXIGA 110MG CAPSULE or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using DABXIGA 110MG CAPSULE . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or a history of bleeding, inform your doctor before taking DABXIGA 110MG CAPSULE .

Uses of DABXIGA 110MG CAPSULE

DABXIGA 110MG CAPSULE is used to prevent and treat blood clots. The detailed uses of DABXIGA 110MG CAPSULE are as follows:

  • Prevention of stroke and blood clots in atrial fibrillation: DABXIGA 110MG CAPSULE is used in patients with non-valvular atrial fibrillation to lower the risk of stroke and blood clots.
  • Treatment of Deep Vein Thrombosis (DVT): DABXIGA 110MG CAPSULE is used to treat blood clots in deep veins, usually in the legs, to prevent them from growing or breaking off.
  • Treatment of Pulmonary Embolism (PE):DABXIGA 110MG CAPSULE is prescribed to treat blood clots in the lungs, helping restore normal blood flow and prevent recurrence.
  • Prevention of Recurrent DVT and PE: DABXIGA 110MG CAPSULE is used to prevent future episodes of DVT and PE in patients with a history of clotting disorders.
  • Prevention of Venous Thromboembolism (VTE) After Orthopaedic Surgery: DABXIGA 110MG CAPSULE is used after hip or knee replacement surgery to prevent the formation of blood clots due to immobility.

Have a query?

Directions for Use

  • DABXIGA 110MG CAPSULE can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow DABXIGA 110MG CAPSULE as a whole with a glass of water.
  • Do not chew, crush, or break it.

Key Benefits

  • DABXIGA 110MG CAPSULE is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation.
  • DABXIGA 110MG CAPSULE prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm).
  • It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.
  • DABXIGA 110MG CAPSULE works by stopping the action of the clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.
  • It helps your blood flow more easily, lowering the chance of dangerous clots forming.

How DABXIGA 110MG CAPSULE Works

DABXIGA 110MG CAPSULE contains Dabigatran, which works by inhibiting the production of clotting factor Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of DABXIGA 110MG CAPSULE helps prevent blood clots if you have an increased risk of having a heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dabxiga 110mg Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of DABXIGA 110MG CAPSULE

Do not take more than the prescribed dose of DABXIGA 110MG CAPSULE as it may cause serious side effects leading to excessive bleeding. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to DABXIGA 110MG CAPSULE or any other medicines, please tell your doctor.
  • You should inform the doctor that you are taking DABXIGA 110MG CAPSULE before any surgery is scheduled.
  • DABXIGA 110MG CAPSULE can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural).
  • Do not stop taking DABXIGA 110MG CAPSULE of your own. Stopping a sudden intake of DABXIGA 110MG CAPSULE may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of DABXIGA 110MG CAPSULE .
  • If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking DABXIGA 110MG CAPSULE .
  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using DABXIGA 110MG CAPSULE .
  • Safety and effectiveness of DABXIGA 110MG CAPSULE have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age.
  • Avoid consumption of alcohol while taking DABXIGA 110MG CAPSULE as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateUrokinase
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Dabxiga 110mg Capsule:
When Mifepristone is taken with Dabxiga 110mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabxiga 110mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateUrokinase
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Taking Dabxiga 110mg Capsule with Urokinase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabxiga 110mg Capsule with Urokinase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDalteparin
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Using dabigatran together with dalteparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Dabxiga 110mg Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
Dabigatran etexilateEptifibatide
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Taking Dabxiga 110mg Capsule with Eptifibatide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabxiga 110mg Capsule with Eptifibatide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilatePrimidone
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Taking Dabxiga 110mg Capsule with Primidone can increase the risk of bleeding.

How to manage the interaction:
Taking Dabxiga 110mg Capsule with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateSulindac
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Combining Sulindac with Dabxiga 110mg Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Dabxiga 110mg Capsule with Sulindac together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateKetoconazole
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Coadministration of Ketoconazole and Dabxiga 110mg Capsule may increase the blood levels and effects Dabxiga 110mg Capsule. This may increase the risk of anemia and bleeding issues.

How to manage the interaction:
Although taking Ketoconazole and Dabxiga 110mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice paleness, exhaustion, dizziness, fainting, unusual bleeding or bruising, swelling, nausea, vomiting, blood in your urine or stools, headache, or weakness, consult a doctor. Do not discontinue any medication without consulting a doctor.
Dabigatran etexilateVerapamil
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Taking Verapamil with Dabxiga 110mg Capsule may increase the blood levels and effects of dabigatran. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Dabxiga 110mg Capsule and Verapamil together may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, or weakness. Do not discontinue any medication without consulting a doctor.
Dabigatran etexilateAspirin
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Using dabigatran with aspirin, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between aspirin and Dabxiga 110mg Capsule, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting doctor.
Dabigatran etexilateCabozantinib
Severe
How does the drug interact with Dabxiga 110mg Capsule:
Taking Dabxiga 110mg Capsule with Cabozantinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabxiga 110mg Capsule with Cabozantinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRANHerbal products/medicines

Drug-Food Interactions

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DABIGATRANHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabxiga 110mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabxiga 110mg Capsule treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of heart disease.

Habit Forming

No

Therapeutic Class

[ANTICOAGULANT/ANTITHROMBOTIC]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with DABXIGA 110MG CAPSULE as it may increase the risk of bleeding.

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Pregnancy

Consult your doctor

DABXIGA 110MG CAPSULE is unsafe to use during pregnancy since it affects the foetus. Please talk to your doctor if you are planning to become pregnant or already pregnant before starting DABXIGA 110MG CAPSULE .

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Breast Feeding

Consult your doctor

There is limited data on how DABXIGA 110MG CAPSULE affects breastfeeding. However, it is unsafe to use DABXIGA 110MG CAPSULE if you are lactating, since it passes through the breast milk and harm the baby. Please consult your doctor before starting DABXIGA 110MG CAPSULE .

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Driving

Consult your doctor

DABXIGA 110MG CAPSULE usually does not affect your ability to drive or operate machinery. Consult your doctor if you have any concerns.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases.However, it is not recommended in patients with severe kidney diseases.

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Children

Unsafe

DABXIGA 110MG CAPSULE is not recommended for children below the age of 18 years. The safety and efficacy of DABXIGA 110MG CAPSULE have not been established in children.

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Heart

Caution

DABXIGA 110MG CAPSULE should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using DABXIGA 110MG CAPSULE .

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Geriatrics

Caution

DABXIGA 110MG CAPSULE should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using DABXIGA 110MG CAPSULE .

FAQs

DABXIGA 110MG CAPSULE belongs to a class of drugs known as anticoagulants or blood thinners used to prevent the risk of stroke and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation.

Please consult your doctor if DABXIGA 110MG CAPSULE needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking DABXIGA 110MG CAPSULE a few days before surgery since it can cause an increased risk of bleeding during surgery. It also causes a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural). This type of blood clot could cause long-term paralysis.

DABXIGA 110MG CAPSULE is generally safe to take for a long time. It works best if you take it for many months or even years. It is advisable please consult your doctor and take DABXIGA 110MG CAPSULE for as long as your doctor has prescribed it.

Taking DABXIGA 110MG CAPSULE during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting DABXIGA 110MG CAPSULE .

DABXIGA 110MG CAPSULE consists of Dabigatran is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

No, you are not recommended to stop taking DABXIGA 110MG CAPSULE without consulting your doctor to worsen the condition. Therefore, take DABXIGA 110MG CAPSULE for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take DABXIGA 110MG CAPSULE with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take DABXIGA 110MG CAPSULE as prescribed by your doctor. Depending on your medical conditions, you are advised to take DABXIGA 110MG CAPSULE as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with DABXIGA 110MG CAPSULE as it may increase the risk of bleeding.

Hair loss is not a known side effect of DABXIGA 110MG CAPSULE . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing DABXIGA 110MG CAPSULE . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep DABXIGA 110MG CAPSULE out of the sight and reach of children.

Yes, bleeding is the main risk associated with DABXIGA 110MG CAPSULE treatment; patients should be monitored for signs of bleeding.

DABXIGA 110MG CAPSULE is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing DABXIGA 110MG CAPSULE .

Common side effects of DABXIGA 110MG CAPSULE may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - DAB0408

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