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Dapabite M 5/1000mg Tablet is used to treat type 2 diabetes mellitus. It contains Metformin and Dapagliflozin which work by eliminating excess sugars from the body through urine and restoring the body's response to insulin. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, headache, and dizziness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Corona Remedies Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dapabite M 5/1000mg Tablet

Dapabite M 5/1000mg Tablet is a prescription oral tablet used to manage high blood sugar in adults with type 2 diabetes. By combining two distinct blood sugar-lowering actions, this medication helps control glucose levels and supports long-term diabetes management. It is prescribed alongside a personalised diet and physical activity plan to achieve the best therapeutic results.

To ensure its effectiveness, you should take Dapabite M 5/1000mg Tablet consistently at the same times every day as directed by your healthcare provider. It is generally recommended to take this tablet with food, which helps minimise the chance of experiencing a temporary upset stomach. Combining this medication with healthy lifestyle choices, such as eating high-fibre foods and engaging in regular exercise, significantly enhances your blood sugar control.

While many patients tolerate this medicine well, some may experience mild side effects like a temporary upset stomach or mild urinary tract infections. It is critical to contact your doctor immediately if you experience signs of rare but serious issues, such as severe dehydration, unusual muscle pain, or rapid, deep breathing. Your healthcare provider will monitor your progress to ensure the medicine is working safely for you.

Do not take this if you have severe kidney disease, liver damage, or a history of diabetic ketoacidosis. Before starting Dapabite M 5/1000mg Tablet , it is highly important to discuss your complete medical history with your doctor, especially if you have heart failure, moderate kidney issues, or a history of frequent urinary tract infections. Your doctor will evaluate if this specific combination is safe for your organs.

This medication can interact with other substances, such as iodinated contrast dyes used in medical scans or heavy alcohol consumption, both of which can increase the risk of a rare but serious metabolic condition. If you are pregnant, breastfeeding, planning a pregnancy, or are an elderly patient, you must consult your healthcare provider to discuss alternative options. Always disclose all prescription and over-the-counter medicines you are currently taking.

Uses of Dapabite M 5/1000mg Tablet

Dapabite M 5/1000mg Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Dapabite M 5/1000mg Tablet are as follows: 

  • Type 2 Diabetes Mellitus: Dapabite M 5/1000mg Tablet is used to improve blood sugar control in adults when lifestyle changes or other single medications do not provide adequate control.
  • Reduction of Cardiovascular Risks: In patients with type 2 diabetes and established heart disease, this combination helps lower the risk of hospitalisation due to heart failure.

Key Benefits

Dapabite M 5/1000mg Tablet helps maintain healthy blood sugar levels while providing long-term benefits for your overall health. With regular use, it supports steady energy levels, reduces the risk of diabetes-related complications, and promotes heart and kidney health.

  • Helps Maintain Stable Blood Sugar and Energy Levels: By keeping your blood sugar within a healthy range, this medicine helps reduce the sluggishness and fatigue associated with high blood glucose, supporting consistent energy throughout the day.
  • Protects Against Long-Term Diabetes Complications: Consistent blood sugar control helps lower the risk of complications such as kidney damage, vision loss, and nerve damage in the hands and feet, supporting long-term health.
  • Supports Heart and Kidney Health: One of the active ingredients helps remove excess sodium and water from the body, reducing strain on the heart while supporting cardiovascular and kidney health.
Side effects of Dapabite M 5/1000mg Tablet
  • Vaginal yeast infections need immediate medical attention.
  • Eat healthy foods like whole grains, lean protein and probiotics.
  • Keep your blood sugar levels in the medium range, which can help reduce the risk of yeast infections.
  • Wash your vulva well to prevent contamination, and after using the toilet, wipe from the front to prevent the spread of infection.
  • Avoid tight-fitting clothes as they may increase moisture and heat in the affected area. Ensure to use cotton underwear only.
  • Frequently change pads or tampons and always keep the effects dry.
  • Avoid sprays, perfumes and deodorants in the vaginal area, as they can change the normal balance of organisms in the vagina.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Take Dapabite M 5/1000mg Tablet with meals or as advised by your doctor.
  • It is advised to take Dapabite M 5/1000mg Tablet once daily; however, follow your doctor's recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

How Dapabite M 5/1000mg Tablet Works

Dapabite M 5/1000mg Tablet combines two different active ingredients that target blood sugar through separate pathways in the body. The first active ingredient, dapagliflozin, belongs to a class of medicines called SGLT2 inhibitors. It works directly on your kidneys to block the reabsorption of glucose, allowing your body to flush out excess sugar through your urine. The second active ingredient, metformin, is a biguanide that works in three distinct ways. First, it reduces the amount of glucose that your liver produces and releases into your bloodstream. Second, it slows down the absorption of sugar from the food you eat. Third, it improves your body's sensitivity to insulin, helping your muscles use glucose more efficiently. Together, these two mechanisms provide a coordinated approach to keeping your blood sugar levels stable throughout the day and night.
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Alcohol

Unsafe

It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.

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Pregnancy

Unsafe

Dapagliflozin in Dapabite M 5/1000mg Tablet is not recommended during the second or third trimester of pregnancy. Your doctor may suggest other medications to control your blood sugar levels. Please consult your doctor before starting Dapabite M 5/1000mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Dapabite M 5/1000mg Tablet may be unsafe to use during breastfeeding since it is excreted into the breast milk. Please seek medical advice for further information.

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Driving

Unsafe

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment when prescribed Dapabite M 5/1000mg Tablet .

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Kidney

Unsafe

Dapabite M 5/1000mg Tablet is contraindicated in patients with severe renal impairment/kidney diseases. Let your doctor know if you have any history of kidney diseases when you are prescribed Dapabite M 5/1000mg Tablet .

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Children

Unsafe

Dapabite M 5/1000mg Tablet is not recommended for people younger than 18 years of age.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before using Dapabite M 5/1000mg Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Dapabite M 5/1000mg Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Dapabite M 5/1000mg Tablet

In case of an accidental overdose, seek immediate medical attention. An overdose can cause dangerously low blood sugar or a serious metabolic condition. Watch for symptoms such as severe nausea, rapid breathing, dizziness, or extreme weakness, and seek emergency help right away.

Diet & Lifestyle Advise

  • Stay adequately hydrated: Because this medicine removes sugar and fluid through your urine, make sure to drink plenty of water throughout the day to prevent dehydration.
  • Follow a low-glycemic diet: Focus on whole foods, lean proteins, high-fibre vegetables, and complex carbohydrates while limiting sugary snacks, white bread, and sodas.
  • Maintain a consistent exercise routine: Aim for at least 150 minutes of moderate aerobic activity, like brisk walking, per week to help your muscles use glucose more effectively.
  • Monitor your blood sugar: Check your blood sugar levels regularly as advised by your doctor, and keep a log of the readings to share at your next medical appointment.
  • Perform daily foot self-checks: Diabetes can affect blood flow and nerve endings in your feet. Inspect your feet daily for any cuts, blisters, redness, or swelling.
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How Soon It Starts Working

The time required for Dapabite M 5/1000mg Tablet to start to work: Dapabite M 5/1000mg Tablet ideally shows its action within a few hours after administration. 

The time for which the effects of Dapabite M 5/1000mg Tablet last: The effect of Dapabite M 5/1000mg Tablet lasts for 24 hours.

What if you forget to take Dapabite M 5/1000mg Tablet

If you miss a dose of Dapabite M 5/1000mg Tablet , take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you are unsure of what to do.

Storage

• Store Dapabite M 5/1000mg Tablet tablets at room temperature, buy preserving them between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Hydration is key: Keep a water bottle with you and drink fluids regularly to prevent dry mouth and dizziness.
  • Limit alcohol: Avoid drinking heavy amounts of alcohol while taking this medicine, as it can significantly increase your risk of lactic acidosis.
  • Check prior to medical scans: Tell your medical team you take Dapabite M 5/1000mg Tablet before any scan requiring iodinated contrast dye, as you may need to temporarily pause the medicine.
  • Watch for yeast infections: Be alert to itching, burning, or discharge in genital areas, and seek prompt treatment if these symptoms develop.
  • Inform surgeons before procedures: If you are planning to have surgery, talk to your doctor, as you may need to stop taking Dapabite M 5/1000mg Tablet several days before the operation to avoid complications.

Drug-Drug Interactions

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  • Contrast Media (Iodinated Dyes): May increase the risk of kidney issues and lactic acidosis; the medication is usually stopped temporarily before and after the procedure.
  • Diuretics (Water Pills): May increase the risk of dehydration and low blood pressure when combined with Dapabite M 5/1000mg Tablet .
  • Insulin and Sulfonylureas: May increase the risk of low blood sugar when combined with this medicine, requiring a dose adjustment of your other diabetes medications.

Drug-Drug Interactions

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How does the drug interact with Dapabite M 5/1000mg Tablet:
Co-administration of Gatifloxacin with Dapagliflozin and Metformin may alter blood glucose levels.

How to manage the interaction:
Although there is a possible interaction of Gatifloxacin with Dapagliflozin and Metformin, it can be taken if prescribed by a doctor. Consult a doctor if you experience nervousness, headache, dizziness, weakness, perspiration, palpitation, increased urination, or increased thirst and hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dapabite M 5/1000mg Tablet:
Co-administration of Acetazolamide with Metformin and Dapagliflozin may increase the risk of low sugar levels or lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction of Acetazolamide with Metformin and Dapagliflozin, you can take these medicines when prescribed by your doctor. However, if you have symptoms such as weakness, muscle pain, difficulty breathing, dizziness, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dapabite M 5/1000mg Tablet:
Coadministration of Topiramate with Metformin and Dapagliflozin may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration of Topiramate with Metformin and Dapagliflozin can lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience symptoms such as weakness, muscle pain, fatigue, breathing difficulty, or palpitations, consult a doctor immediately. Do not stop using any medication without a doctor's advice.
How does the drug interact with Dapabite M 5/1000mg Tablet:
Co-administration of Aliskiren with Dapagliflozin and Metformin may increase the risk of dehydration and low blood pressure.

How to manage the interaction:
Taking Aliskiren with Dapagliflozin and Metformin can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, headache, excessive sweating, or palpitations, contact a doctor. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Dapabite M 5/1000mg Tablet:
Co-administration of Methazolamide with Metformin and Dapagliflozin may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction of Methazolamide with Metformin and Dapagliflozin, you can take these medicines together if prescribed by your doctor. However, if you have symptoms such as weakness, muscle pain, respiratory distress, fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, or chills, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Dapabite M 5/1000mg Tablet:
Coadministration of Zonisamide with Dapagliflozin and Metformin may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration of Zonisamide with Dapagliflozin and Metformin can lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience any symptoms such as weakness, muscle pain, palpitations, or breathing difficulty, consult a doctor immediately. Do not stop using any medication without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

Alcohol: Avoid excessive alcohol consumption, as it can dangerously increase the risk of lactic acidosis and alter blood sugar control.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Dapabite M 5/1000mg Tablet belongs to the class of antidiabetic drugs, primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. Dapabite M 5/1000mg Tablet also lowers the risk of heart failure in type 2 diabetic patients with heart diseases.
Dapabite M 5/1000mg Tablet contains two antidiabetic medicines: Metformin and Dapagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.
Dapabite M 5/1000mg Tablet may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Dapabite M 5/1000mg Tablet with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda.
Your doctor may advise Dapabite M 5/1000mg Tablet with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using Dapabite M 5/1000mg Tablet with or without other antidiabetic drugs.
Dapabite M 5/1000mg Tablet should be used with caution in heart, kidney or liver diseases, breathing problems (asthma, obstructive lung disease), blood disorders (anaemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and yeast infection of genitals. Dapabite M 5/1000mg Tablet is contraindicated in patients with severe renal impairment and metabolic acidosis/diabetic ketoacidosis.
While using Dapabite M 5/1000mg Tablet , if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing, or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.
It is not recommended to use Dapabite M 5/1000mg Tablet along with water pills/diuretics. Simultaneous use of Dapabite M 5/1000mg Tablet and water pills causes dehydration and may increase the risk of lactic acidosis.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
The side effects of Dapabite M 5/1000mg Tablet include headache, nausea, vomiting, diarrhoea, runny or stuffy nose, sore throat and genital infections. If these side effects persist or worsen, please consult your doctor.
You are recommended to consult your doctor before taking Dapabite M 5/1000mg Tablet with insulin as it may increase the risk of hypoglycemia (low blood sugar). You may need a dose adjustment or regular monitoring of blood sugar to use these medicines safely.
No, avoid taking Dapabite M 5/1000mg Tablet if you have any kidney problems, as it works by excreting excess sugar through urine.
No, usually Dapabite M 5/1000mg Tablet does not cause loss of body weight. On the other hand, rapid loss of body weight is a sign of a Diabetic ketoacidosis, a serious medical condition.
No, Dapabite M 5/1000mg Tablet is only useful in type 2 diabetes mellitus, in which the body either produces less amount of insulin or cannot utilise it.
No, this medicine is generally not recommended during pregnancy. If you are planning a pregnancy or become pregnant, talk to your doctor to switch to a safer blood sugar-lowering treatment.
Persistent, severe diarrhoea can lead to dehydration and increase the risk of side effects. Stop taking the medicine temporarily and talk to your doctor or pharmacist immediately.
It is highly recommended to limit or avoid alcohol, especially heavy drinking, because it increases the risk of a rare but life-threatening condition called lactic acidosis. Talk to your doctor about safe alcohol limits.
One of the active ingredients causes your body to pass more sugar and water out through your urine. Drinking plenty of water prevents dehydration and reduces the risk of urinary tract infections. Talk to your doctor if you struggle to stay hydrated.
You must inform your surgeon or radiologist that you are taking Dapabite M 5/1000mg Tablet . You may need to stop taking the medicine temporarily before major surgery or scans involving iodinated contrast dyes. Talk to your doctor for specific instructions.

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Country of origin

India

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059
Other Info - DAP0089
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