Dashori 70 Tablet 60's
MRP ₹11127
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About Dashori 70 Tablet
Dashori 70 Tablet is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. Dashori 70 Tablet is used in the treatment of chronic myelogenous leukemia (CML) in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) who are resistant or intolerant to prior therapy, in patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia (CML). This medicine is also used in the treatment of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).
Dashori 70 Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.
Dashori 70 Tablet may cause certain side effects, such as skin rash, fatigue, headache, musculoskeletal pain, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, GI bleeding, muscle inflammation, myalgia, and difficulty breathing. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dashori 70 Tablet should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Dashori 70 Tablet based on the severity of your condition.
Dashori 70 Tablet should be avoided if you are allergic to it or any other components present in it. Before taking Dashori 70 Tablet , caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, cardiac problems, and myelosuppression as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Dashori 70 Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment.
Uses of Dashori 70 Tablet
Dashori 70 Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. The detailed uses of Dashori 70 Tablet are as follows:
- Chronic Myeloid Leukemia (CML): Dashori 70 Tablet is used to treat chronic myeloid leukemia especially philadelphia chromosome-positive (Ph+) CML, in both newly diagnosed and resistant/intolerant cases.
- Acute Lymphoblastic Leukemia (ALL): Dashori 70 Tablet is used to treat acute lymphoblastic leukemia and also Ph+ ALL, who are newly diagnosed or have relapsed.
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Directions for Use
- Dashori 70 Tablet can be taken with or without food, as food does not affect its absorption or effectiveness.
- It is usually taken once a day, or as prescribed by your doctor.
- Swallow Dashori 70 Tablet as a whole with water.
- Do not crush, chew or break Dashori 70 Tablet .
Medicinal Benefits
Dashori 70 Tablet contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins (BCR-ABL tyrosine kinase) that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. Dashori 70 Tablet is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.
How Dashori 70 Tablet Works
Storage
- Eat well-cooked food to minimize infection risk.
- Practice good hand hygiene to prevent infections.
- Avoid crowds and people with illnesses to reduce exposure.
- Wear a mask when necessary to lower infection risk.
- Rest adequately to support your body's healing process.
- Stay hydrated by drinking plenty of water.
- Regularly monitor blood cell counts for changes.
- Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
- Consult your doctor right away if concerning symptoms arise.
- Follow your doctor's guidance on managing myelosuppression and infection prevention.
- Avoid diet rich in salt and carbohydrates
- Drink plenty of water and stay hydrated.
- Exercise regularly and maintain a healthy lifestyle.
- Take potassium rich foods like potatoes, spinach, tomatoes, sea food and dairy products.
- Take beverages containing caffeine like coffee and tea.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Tell your doctor immediately if you experience shortness of breath after taking medication.
- Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
- Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
- For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
- Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
- Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
- Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
- Consume calcium-rich dairy products for bone health.
- Eat green and leafy vegetables for essential nutrients.
- Include lean protein sources like eggs and whole grains.
- Use herbs and spices for added flavor and nutrition.
- Choose fortified foods for extra nutritional benefits.
- Get plenty of sleep for overall health and well-being.
What if I have taken an overdose of Dashori 70 Tablet
Drug Warnings
Dashori 70 Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, or gastrointestinal disorders, as the use of Dashori 70 Tablet in these patients may cause serious side effects. Dashori 70 Tablet may cause myelosuppression, fluid retention, gastrointestinal haemorrhage, QT prolongation, congestive heart failure, Left ventricular dysfunction and Myocardial infarction. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Dashori 70 Tablet is given in children above one year of age only if prescribed by the doctor. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Using Mesoridazine together with Dashori 70 Tablet can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Mesoridazine with Dashori 70 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
Using Halofantrine together with Dashori 70 Tablet can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Dashori 70 Tablet with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
Using dronedarone together with Dashori 70 Tablet can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Dashori 70 Tablet with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
Using Pimozide together with Dashori 70 Tablet can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Dashori 70 Tablet with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
Taking Clopidogrel and Dashori 70 Tablet together can increase the risk of bleeding.
How to manage the interaction:
Taking Clopidogrel together with Dashori 70 Tablet may result in an interaction, but they can be taken if prescribed by a doctor. However, if you experience dizzy or lightheaded, red or black, sticky stools, or a severe headache, consult a doctor without any delay. Do not discontinue any medication without consulting a doctor.
Co-administration of Dashori 70 Tablet with Amiodarone may increase the risk of abnormal heart rhythm.
How to manage the interaction:
Although taking Dashori 70 Tablet with Amiodarone may cause an interaction, it is safe if a doctor has prescribed it. If you develop dizziness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.
Using Dashori 70 Tablet together with Diflunisal may increase the risk of bleeding.
How to manage the interaction:
Although taking Diflunisal and Dashori 70 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you notice bruising, feeling dizzy or lightheaded, dark stools, headaches, or weakness contact a doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Dashori 70 Tablet together with Meloxicam may increase the risk of bleeding.
How to manage the interaction:
Co-administration of Meloxicam with Dashori 70 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, red or black, tarry stools, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Using Efavirenz together with Dashori 70 Tablet can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Taking Efavirenz with Dashori 70 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, breathlessness, or heart palpitations. Do not stop using any medications without talking to a doctor.
If Ketoconazole and Dashori 70 Tablet are used together the blood level of Dashori 70 Tablet may increase.
How to manage the interaction:
Although taking Ketoconazole and Dashori 70 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, shortness of breath, or heart palpitations, consult a doctor. Do not discontinue any medication without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit Juice
How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Dashori 70 Tablet. Avoid consumption of Grapefruit juice with Dashori 70 Tablet. However, contact a doctor if you experience dizziness, shortness of breath, heart palpitations, pain, or burning during urination.
Diet & Lifestyle Advise
- After beginning your treatment, several dietary adjustments can help you control side effects.
- Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
- Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast and fried food, processed meats, refined carbs and added sugars.
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Alcohol
Unsafe
Avoid alcohol consumption while on treatment with Dashori 70 Tablet to prevent serious adverse effects.
Pregnancy
Unsafe
When given to a pregnant woman, Dashori 70 Tablet may cause fetal harm. There have been no sufficient and well-controlled investigations of Dashori 70 Tablet in pregnant women. Women of reproductive potential should avoid becoming pregnant while undergoing treatment with this medicine.
Breast Feeding
Unsafe
It is not known if Dashori 70 Tablet passes into your breast milk. Inform your doctor if you are breastfeeding. You should not breastfeed while taking this medicine and for 2 weeks of the treatment with Dashori 70 Tablet . Your doctor may prescribe an alternative based on the symptoms and health condition.
Driving
Unsafe
Dashori 70 Tablet may cause dizziness and may make you feel drowsy. Hence, avoid driving or operating machines after taking Dashori 70 Tablet or until you become alert.
Liver
Caution
Use Dashori 70 Tablet with caution if you have liver disease. Your doctor may monitor your liver function while taking this medicine. No dose adjustments are necessary in patients with liver impairment.
Kidney
Caution
There are presently no clinical investigations with Dashori 70 Tablet in patients with compromised renal function. If you have kidney problems, inform your doctor before taking this medicine.
Children
Consult your doctor
Dashori 70 Tablet is safe for use in children above one year of age if prescribed by the doctor.
Heart
Dashori 70 Tablet may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Dashori 70 Tablet .
Geriatrics
Consult your doctor
Please consult a doctor before administering Dashori 70 Tablet to geriatric patients. Your doctor will prescribe Dashori 70 Tablet if the benefits outweigh the risks.
FAQs
Dashori 70 Tablet is used to treat Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.
Dashori 70 Tablet contains Dasatinib, which works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells.
Dashori 70 Tablet is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least six months after completion of the treatment.
Take antacids such as aluminium hydroxide/magnesium hydroxide, calcium carbonate, calcium carbonate, and magnesium 2 hours before or after taking Dashori 70 Tablet as antacids may alter the absorption of this medicine.
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