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  3. Daunomycin 20Mg Inj

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Daunomycin 20Mg Inj, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Daunomycin 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. It contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying DNA and RNA synthesis. Thus, Daunomycin 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way, and causes cancer cell death.

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Synonym :

DAUNORUBICIN HYDROCHLORIDE

Composition :

DAUNORUBICIN-20MG

Manufacturer/Marketer :

Pharm Products Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Daunomycin 20Mg Inj

Daunomycin 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Daunomycin 20Mg Inj helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Daunomycin 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunomycin 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Daunomycin 20Mg Inj may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Daunomycin 20Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Daunomycin 20Mg Inj is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Daunomycin 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunomycin 20Mg Inj. Daunomycin 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunomycin 20Mg Inj as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Daunomycin 20Mg Inj

Daunomycin 20Mg Inj is used to treat certain types of blood cancers. The detailed uses of Daunomycin 20Mg Inj are as follows:<br/>• Treats acute myeloid leukaemia (AML): Daunomycin 20Mg Inj is used in combination with other chemotherapy drugs to manage AML, a cancer of the white blood cells.<br/>• Used for acute lymphocytic leukaemia (ALL): Daunomycin 20Mg Inj is given with other chemotherapy agents to treat ALL, another type of white blood cell cancer.<br/>• Helps slow cancer growth: Daunomycin 20Mg Inj works by inhibiting the growth and spread of cancer cells in the body.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Daunomycin 20Mg Inj will be administered by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

Daunomycin 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunomycin 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

How Daunomycin 20Mg Inj Works

Daunomycin 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunomycin 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Storage

• Store in a cool and dry place away from sunlight.• Keep Daunomycin 20Mg Inj out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Daunomycin 20Mg Inj
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Daunomycin 20Mg Inj

Daunomycin 20Mg Inj is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Drug Warnings

Daunomycin 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunomycin 20Mg Inj. Daunomycin 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunomycin 20Mg Inj as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Daunomycin 20Mg Inj may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Daunomycin 20Mg Inj as it may cause infections.

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
DaunorubicinInfliximab
Severe

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
How does the drug interact with Daunomycin 20Mg Inj:
Taking Daunomycin 20Mg Inj with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Daunomycin 20Mg Inj with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinInfliximab
Severe
How does the drug interact with Daunomycin 20Mg Inj:
Combining Infliximab with Daunomycin 20Mg Inj can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Daunomycin 20Mg Inj, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor right away. Do not stop using any medications without talking to a doctor.
DaunorubicinBaricitinib
Severe
How does the drug interact with Daunomycin 20Mg Inj:
Using baricitinib together with Daunomycin 20Mg Inj may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Daunomycin 20Mg Inj if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DaunorubicinDisopyramide
Severe
How does the drug interact with Daunomycin 20Mg Inj:
The combined use of Daunomycin 20Mg Inj and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Daunomycin 20Mg Inj and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DaunorubicinMifepristone
Severe
How does the drug interact with Daunomycin 20Mg Inj:
Co-administration of Daunomycin 20Mg Inj with mifepristone may increase the risk of an abnormal heart rate, prolonged treatment with Mifepristone may also cause low potassium levels in the body.

How to manage the interaction:
Taking Daunomycin 20Mg Inj with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
DaunorubicinAmisulpride
Severe
How does the drug interact with Daunomycin 20Mg Inj:
Using Amisulpride together with Daunomycin 20Mg Inj can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Daunomycin 20Mg Inj with Amisulpride together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - like a fast or irregular heartbeat, a heart problem, or feeling dizzy or faint - it's important to let the doctor know. Do not stop using any medications without a doctor's advice.
DaunorubicinGatifloxacin
Severe
How does the drug interact with Daunomycin 20Mg Inj:
Taking Daunomycin 20Mg Inj with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Daunomycin 20Mg Inj with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DaunorubicinAmiodarone
Severe
How does the drug interact with Daunomycin 20Mg Inj:
Coadministration of Daunomycin 20Mg Inj with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Daunomycin 20Mg Inj with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
DaunorubicinCladribine
Severe
How does the drug interact with Daunomycin 20Mg Inj:
The combined use of cladribine with Daunomycin 20Mg Inj can increase the risk of serious infections.

How to manage the interaction:
Taking Daunomycin 20Mg Inj with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without talking to a doctor.
DaunorubicinClozapine
Severe
How does the drug interact with Daunomycin 20Mg Inj:
When Clozapine is taken with Daunomycin 20Mg Inj, may increase the risk of infection and irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Daunomycin 20Mg Inj and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include problems with your immune system, heart rhythm, or signs of infection like fever, chills, or a sore throat. Other symptoms to watch out for are muscle aches, difficulty breathing, unexplained weight loss, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Daunomycin 20Mg Inj as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Daunomycin 20Mg Inj Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol with Daunomycin 20Mg Inj as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before receiving Daunomycin 20Mg Inj.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Daunomycin 20Mg Inj. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Daunomycin 20Mg Inj causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Daunomycin 20Mg Inj.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Daunomycin 20Mg Inj. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Daunomycin 20Mg Inj. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Safe if prescribed

Daunomycin 20Mg Inj can be recommended for acute lymphocytic leukemia in children. Please consult your doctor. Your child's doctor may prescribe a suitable dose based on the condition and age of your child. If this medicine is given, the child should be observed carefully for any unwanted effects.

FAQs

Daunomycin 20Mg Inj is used to treat lymphocytic leukemia, and Acute non-lymphocytic leukemia.

Daunomycin 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Daunomycin 20Mg Inj may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Daunomycin 20Mg Inj if you are planning to become a parent.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Daunomycin 20Mg Inj as it may cause infections.

Yes, Daunomycin 20Mg Inj is a vesicant (irritant) which means, it can cause severe tissue damage if it leaks into the surrounding tissues during injection (extravasation).

Daunomycin 20Mg Inj should be administered by the doctor or nurse through an intravenous route (into a vein). Do not self-administer.

The frequency and duration of treatment may vary depending on your medical condition being treated. Always follow the doctor's instructions regarding the dosing schedule to get full benefits.

The side effects of Daunomycin 20Mg Inj include mouth ulcers, diarrhoea, vomiting, nausea, loss of appetite, dizziness, weakness, fever, chills, and pain at the site of injection. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

AH-64, 5th Street, Shanthi Colony , Anna Nagar,Chennai -600040
Other Info - DAU0002

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:04 AM IST

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Reference

  1. https://go.drugbank.com/drugs/DB00694
  2. https://www.drugs.com/pro/daunorubicin.html#s-34084-4
  3. https://medlineplus.gov/druginfo/meds/a682289.html
  4. https://reference.medscape.com/drug/daunorubicin-342118

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