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  1. Home
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  3. Deghor-120 Injection 1's

Prescription drug
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Deghor-120 Injection 1's, Pack of 1 INJECTION
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Composition :

DEGARELIX-120MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Deghor-120 Injection

Deghor-120 Injection belongs to the group of medicines called gonadotropin-releasing hormone receptor antagonists indicated in the treatment of advanced prostate cancer. Prostate cancer is a cancer that occurs in the man’s prostate, a male reproductive gland.

Deghor-120 Injection contains Degarelix, a synthetic hormone blocker which works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells that require testosterone for their growth.

In some cases, Deghor-120 Injection may cause side effects such as injection site reaction and hot flushes. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, consult your doctor.

Let the doctor know if you are allergic to any of the components in Deghor-120 Injection. This medicine is not intended for use in women. Deghor-120 Injection is not recommended for use in children. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Deghor-120 Injection

Deghor-120 Injection is used in the treatment of Prostate cancer. The detailed uses of Deghor-120 Injection are as follows:

  • Advanced prostate cancer: Deghor-120 Injection is primarily used to treat hormone-dependent prostate cancer in adult men. It works by blocking gonadotropin-releasing hormone (GnRH) receptors, resulting in a rapid reduction in testosterone levels. This decrease in testosterone helps to slow or stop the growth of cancer cells that depend on this hormone.
  • Locally advanced prostate cancer (in combination with radiotherapy):Deghor-120 Injection may be used alongside radiation therapy in patients with high-risk, locally advanced prostate cancer, helping to shrink the tumour and improve treatment outcomes.&
  • Rapid testosterone suppression: Unlike some other hormone therapies, Deghor-120 Injection provides immediate testosterone suppression without the initial surge (flare) seen with GnRH agonists, making it especially useful in patients where a quick hormonal response is critical.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Deghor-120 Injection is given by the doctor or a trained nurse.
  • Do not self-administer.

Medicinal Benefits

Deghor-120 Injection belongs to the group of medicines called gonadotropin-releasing hormone receptor antagonists indicated in the treatment of adult male patients with prostate cancer and high-risk prostate cancer before radiation therapy and in combination with radiotherapy. Deghor-120 Injection contains Degarelix, a synthetic hormone blocker which works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells that require testosterone for their growth. Thereby, it helps treat prostate cancer.

How Deghor-120 Injection Works

Deghor-120 Injection contains Degarelix, a synthetic hormone blocker which works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells that require testosterone for their growth.

Storage

• Store in a cool and dry place away from sunlight.• Keep Deghor-120 Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Deghor-120 Injection
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.

What if I have taken an overdose of Deghor-120 Injection

As Deghor-120 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Do not use Deghor-120 Injection if you are allergic to any of its components. Inform the doctor if you have heart rhythm problems, diabetes mellitus, osteoporosis, heart, liver or kidney problems, high blood pressure, or high/low blood levels of calcium, potassium, magnesium, or sodium in your blood. Avoid rubbing or scratching the injection site. After you receive a dose of Deghor-120 Injection, avoid allowing your body fluids to come into contact with your hands or other surfaces for at least 48 hours. Let the doctor know if you are taking any prescription/non-prescription medications, including herbal products and supplements.

Drug-Drug Interactions

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DegarelixZiprasidone
Critical
DegarelixCeritinib
Severe

Drug-Drug Interactions

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DegarelixZiprasidone
Critical
How does the drug interact with Deghor-120 Injection:
Taking Deghor-120 Injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Deghor-120 Injection with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DegarelixCeritinib
Severe
How does the drug interact with Deghor-120 Injection:
Taking Deghor-120 Injection with Ceritinib can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
There may be a possibility of interaction between Deghor-120 Injection and Ceritinib, but it can be taken if prescribed by a doctor. If you experience any symptoms like dizziness, fainting, or difficulty breathing, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DegarelixClozapine
Severe
How does the drug interact with Deghor-120 Injection:
Combining Deghor-120 Injection with Clozapine can increase the risk of QTc prolongation.

How to manage the interaction:
Co-administration of Deghor-120 Injection with Clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like changes in your heart rhythm, feeling dizzy or lightheaded, or having trouble breathing, it's important to call your doctor right away. Do not discontinue any medications without consulting a doctor.
DegarelixAmiodarone
Severe
How does the drug interact with Deghor-120 Injection:
Coadministration of Deghor-120 Injection with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Deghor-120 Injection with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
DegarelixAmisulpride
Severe
How does the drug interact with Deghor-120 Injection:
Using amisulpride together with Deghor-120 Injection can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although taking Deghor-120 Injection and Amisulpride together can cause an interaction, it can be taken if a doctor has suggested it. If you experience symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
DegarelixEfavirenz
Severe
How does the drug interact with Deghor-120 Injection:
Taking Deghor-120 Injection and Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Deghor-120 Injection and Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DegarelixMoxifloxacin
Severe
How does the drug interact with Deghor-120 Injection:
Using Moxifloxacin together with Deghor-120 Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Deghor-120 Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or irregular heartbeat, contact a doctor right away. Do not discontinue any medications without consulting a doctor,
DegarelixSotalol
Severe
How does the drug interact with Deghor-120 Injection:
Using sotalol together with Deghor-120 Injection can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Deghor-120 Injection, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
DegarelixEscitalopram
Severe
How does the drug interact with Deghor-120 Injection:
Combining Deghor-120 Injection with Escitalopram can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Deghor-120 Injection with Escitalopram together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like dizziness, fainting, or abnormal heart rhythm, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
DegarelixHaloperidol
Severe
How does the drug interact with Deghor-120 Injection:
Co-administration of Deghor-120 Injection with Haloperidol can increase the risk of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Deghor-120 Injection with Haloperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Deghor-120 Injection Substitute

Substitutes safety advice
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Alcohol

Consult your doctor

It is not known whether Deghor-120 Injection interacts with alcohol. Please consult your doctor.

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Caution

In some cases, Deghor-120 Injection may cause dizziness or tiredness. So, drive or operate machinery only if you are alert.

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Liver

Caution

If you have a history of liver disease, please inform the doctor before receiving Deghor-120 Injection. Liver function may need to be monitored in patients with liver disease.

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Kidney

Caution

If you have a history of kidney disease, please inform the doctor before receiving Deghor-120 Injection.

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Children

Unsafe

Deghor-120 Injection is not recommended for children as the safety and effectiveness have not been established.

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Heart

If you have a history of heart disease, please inform the doctor before receiving Deghor-120 Injection.

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Geriatrics

Consult your doctor

Limited information available about the use of Deghor-120 Injection in geriatric patients. Please consult your physician.

FAQs

Deghor-120 Injection is used to treat Prostate cancer.

Deghor-120 Injection works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells.

Deghor-120 Injection may decrease fertility. If you have any concerns regarding this, please consult the doctor.

Worsening or onset of diabetes may occur. Therefore, if you have diabetes, inform the doctor. You may need to check your blood glucose levels more regularly if you have diabetes.

Country of origin

INDIA

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - DEG0016

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Keep Refrigerated. Do not freeze.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:50 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6535.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022201lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a609022.html
  4. https://www.drugs.com/degarelix.html

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