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About DEGARELIX

DEGARELIX belongs to the group of medicines called gonadotropin-releasing hormone receptor antagonists indicated in the treatment of advanced prostate cancer. Prostate cancer is a cancer that occurs in the man’s prostate, a male reproductive gland.
 
DEGARELIX contains Degarelix, a synthetic hormone blocker which works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells that require testosterone for their growth.
 
In some cases, DEGARELIX may cause side effects such as injection site reaction and hot flushes. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, consult your doctor.
 
Let the doctor know if you are allergic to any of the components in DEGARELIX. This medicine is not intended for use in women. DEGARELIX is not recommended for use in children. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of DEGARELIX

Prostate cancer

Medicinal Benefits

DEGARELIX belongs to the group of medicines called gonadotropin-releasing hormone receptor antagonists indicated in the treatment of adult male patients with prostate cancer and high-risk prostate cancer before radiation therapy and in combination with radiotherapy. DEGARELIX contains Degarelix, a synthetic hormone blocker which works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells that require testosterone for their growth. Thereby, it helps treat prostate cancer.

Directions for Use

DEGARELIX will administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DEGARELIX

  • Injection site reactions (pain, redness, swelling)
  • Hot flushes
  • Weight gain
  • Nausea
  • Diarrhoea
  • Dizziness
  • Headache
  • Tiredness

In-Depth Precautions and Warning

Drug Warnings

Do not use DEGARELIX if you are allergic to any of its components. Inform the doctor if you have heart rhythm problems, diabetes mellitus, osteoporosis, heart, liver or kidney problems, high blood pressure, or high/low blood levels of calcium, potassium, magnesium, or sodium in your blood. Avoid rubbing or scratching the injection site. After you receive a dose of DEGARELIX, avoid allowing your body fluids to come into contact with your hands or other surfaces for at least 48 hours. Let the doctor know if you are taking any prescription/non-prescription medications, including herbal products and supplements.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking drugs used to treat heart rhythm problems (quinidine, procainamide, amiodarone, sotalol), pain killers (methadone), antibiotics (moxifloxacin), and antipsychotics.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have heart rhythm problems, diabetes mellitus, or osteoporosis.

Drug-Drug Interactions Checker List:

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      It is not known whether DEGARELIX interacts with alcohol. Please consult your doctor.

    • Safety Warning

      Pregnancy

      not applicable

      -

    • Safety Warning

      Breast Feeding

      not applicable

      -

    • Safety Warning

      Driving

      caution

      In some cases, DEGARELIX may cause dizziness or tiredness. So, drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      If you have a history of liver disease, please inform the doctor before receiving DEGARELIX. Liver function may need to be monitored in patients with liver disease.

    • Safety Warning

      Kidney

      caution

      If you have a history of kidney disease, please inform the doctor before receiving DEGARELIX.

    • Safety Warning

      Children

      unsafe

      DEGARELIX is not recommended for children as the safety and effectiveness have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a healthy diet and exercise regularly to maintain proper weight.
    • Avoid smoking and alcohol consumption.
    • Avoid fast, fried, processed meats, refined carbs, and added sugar.
    • Get optimal sleep; rest well.

    Patients Concern

    Disease/Condition Glossary

    Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a reproductive gland in men that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning sensation during urination.

    FAQs

    How does DEGARELIX work?

    DEGARELIX works by decreasing the amount of testosterone and helps to stop or slow the spread of prostate cancer cells.

    Does DEGARELIX affect fertility?

    DEGARELIX may decrease fertility. If you have any concerns regarding this, please consult the doctor.

    Is DEGARELIX safe for patients with diabetes?

    Worsening or onset of diabetes may occur. Therefore, if you have diabetes, inform the doctor. You may need to check your blood glucose levels more regularly if you have diabetes.

    Available Medicines for

    DEGARELIX