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compositionComposition:DIENOGEST-2MG
prescriptionPrescription Medicine
Denoreg 2 mg Tablet 10's

DENOREG 2 TABLETS is used to treat endometriosis. It contains Dienogest, which suppresses the production of a hormone (oestradiol) that causes excess growth in the endometrium. In some cases, this medicine may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DIENOGEST-2MG

Manufacturer/Marketer :

Pharmison Valentes Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About DENOREG 2 TABLETS

DENOREG 2 TABLETS is used for the management of painful symptoms of endometriosis. Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.

DENOREG 2 TABLETS contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, DENOREG 2 TABLETS helps in treating pelvic pain associated with endometriosis.

In some cases, DENOREG 2 TABLETS may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Do not take DENOREG 2 TABLETS if you are allergic to any of its components. Avoid taking DENOREG 2 TABLETS if you are pregnant, planning for pregnancy or breastfeeding. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of DENOREG 2 TABLETS

DENOREG 2 TABLETS is used in the management of endometriosis. The detailed uses of DENOREG 2 TABLETS are as follows:

  • Manages Endometriosis: DENOREG 2 TABLETS helps relieve pelvic pain and inflammation associated with endometriosis by suppressing the production of estradiol (a hormone) and preventing the abnormal growth of endometrial tissue outside the uterus.
  • Manages Heavy Menstrual Bleeding: It may help control and reduce prolonged or heavy menstrual bleeding (menorrhagia) associated with endometriosis.
  • Support in Menopausal Hormonal Therapy: It may be used as part of hormone replacement therapy during menopause (the permanent end of periods) to balance hormone levels and relieve menopausal symptoms such as hot flashes and vaginal dryness.

Key Benefits

  • DENOREG 2 TABLETS is primarily indicated for the management of endometriosis, a condition where tissue similar to the lining of the uterus (endometrium) grows outside the uterus, causing pain and other symptoms.
  • It works by suppressing the production of estradiol, a hormone that promotes the abnormal growth of endometrial tissue.
  • By reducing estradiol levels, DENOREG 2 TABLETS helps shrink endometrial tissue and relieve pain and discomfort associated with endometriosis.
  • It regulates hormone levels and may also help reduce excessive menstrual bleeding, making it useful in the treatment of heavy periods.
  • DENOREG 2 TABLETS can be used as part of hormone replacement therapy (HRT) in menopausal women to balance estrogen levels, reducing the risk of endometrial thickening and providing symptom relief.
  • It provides effective hormonal control to manage endometriosis, reduce pelvic pain, regulate heavy bleeding, and support hormone balance during menopause.
Side effects of Denoreg 2 mg Tablet
Here are the six steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • DENOREG 2 TABLETS can be taken with or without food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow DENOREG 2 TABLETS as a whole with a glass of water.
  • Do not chew, crush, or break it.

How DENOREG 2 TABLETS Works

DENOREG 2 TABLETS contains Dienogest, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, DENOREG 2 TABLETS helps in treating pelvic pain associated with endometriosis.
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Alcohol

Caution

It is unknown if DENOREG 2 TABLETS interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

DENOREG 2 TABLETS is not recommended during pregnancy. Please consult your doctor if you have any concerns regarding this. Consult your doctor immediately if you become pregnant while taking DENOREG 2 TABLETS .

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Breast Feeding

Unsafe

Avoid taking DENOREG 2 TABLETS if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

DENOREG 2 TABLETS may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be necessary. DENOREG 2 TABLETS should not be taken by people with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

DENOREG 2 TABLETS should not be given to children who have not had their first period.

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Heart

Caution

DENOREG 2 TABLETS should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking DENOREG 2 TABLETS .

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Geriatrics

Unsafe

DENOREG 2 TABLETS is not intended for use or prescribing in elderly patients.

What if I have taken an overdose of DENOREG 2 TABLETS

An overdose of DENOREG 2 TABLETS may cause unpleasant side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Include diet-fibrous foods, iron-rich foods, foods rich in essential fatty acids, and antioxidant-rich foods.
  • Maintain a healthy diet and exercise regularly.
  • Practice meditation and yoga. Acupuncture and massages can also be helpful.
  • Avoid or limit caffeine intake.

Have a query?

How Soon It Starts Working

The time required for DENOREG 2 TABLETS to start to work: DENOREG 2 TABLETS ideally shows its action within 1.5 to 2 hours after administration.

The time for which the effects of DENOREG 2 TABLETS last: The effect of DENOREG 2 TABLETS lasts for 24 hours.

What if you forget to take DENOREG 2 TABLETS

If you miss a dose of DENOREG 2 TABLETS , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep DENOREG 2 TABLETS out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take DENOREG 2 TABLETS if you are allergic to any of its components.
  • DENOREG 2 TABLETS is not recommended if you have a blood clot in the lungs, heart, brain, blood vessels of legs or any part of the body, if you have/had diabetes mellitus with damaged blood vessels, severe liver damage, unexplained vaginal bleeding, or a benign or malignant tumour.
  • Talk to your doctor if you have diabetes, high blood pressure, depression, are overweight, have chloasma (yellowish-brown pigmentation on the skin), had an ectopic pregnancy (embryo develops outside the womb), or if you or anyone in your immediate family has had blood clots in lungs/legs, or heart attack, high cholesterol or stroke.
  • Avoid taking DENOREG 2 TABLETS if you are pregnant, planning for pregnancy or breastfeeding.
  • Consult your doctor immediately if you become pregnant while taking DENOREG 2 TABLETS .
  • DENOREG 2 TABLETS should not be given to children who have not had their first period.
  • DENOREG 2 TABLETS may cause dizziness, so drive with caution.
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions: DENOREG 2 TABLETS may interact with anti-epileptics (phenytoin, primidone, carbamazepine, oxcarbazepine, topiramate, felbamate, phenobarbitone), anti-depressants (fluoxetine, fluvoxamine), anti-hypertensives (diltiazem, verapamil), anti-TB (rifampicin, rifabutin), anti-fungal (ketoconazole, itraconazole, fluconazole, voriconazole), antibiotics (erythromycin, clarithromycin), antacids (cimetidine), and herbal supplements used to treat depression (St. John’s wort).

Drug-Food Interactions: Avoid consumption of grapefruit while taking DENOREG 2 TABLETS . 

Drug-Disease Interactions: Inform your doctor if you have diabetes mellitus with damaged blood vessels, severe liver damage, unexplained vaginal bleeding, or a benign or malignant tumour.

DienogestEfavirenz
Critical
DienogestCarbamazepine
Severe

Drug-Drug Interactions

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DienogestEfavirenz
Critical
How does the drug interact with Denoreg 2 mg Tablet:
When Efavirenz is taken with Denoreg 2 mg Tablet, it can lower the metabolism of Denoreg 2 mg Tablet and increase the risk or severity of side effects.

How to manage the interaction:
Taking Efavirenz with Denoreg 2 mg Tablet can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
DienogestCarbamazepine
Severe
How does the drug interact with Denoreg 2 mg Tablet:
Taking carbamazepine with Denoreg 2 mg Tablet may increase the effect of carbamazepine.

How to manage the interaction:
Although there is a possible interaction, Denoreg 2 mg Tablet can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
DienogestFosphenytoin
Severe
How does the drug interact with Denoreg 2 mg Tablet:
When Denoreg 2 mg Tablet is taken with Fosphenytoin, it can increase the risk of severe bleeding.

How to manage the interaction:
Although taking Denoreg 2 mg Tablet and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DienogestDantrolene
Severe
How does the drug interact with Denoreg 2 mg Tablet:
Co-administration of Dantrolene with Denoreg 2 mg Tablet can cause serious side effects that may affect your liver.

How to manage the interaction:
Taking Denoreg 2 mg Tablet with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
DienogestBosentan
Severe
How does the drug interact with Denoreg 2 mg Tablet:
Co-administration of Denoreg 2 mg Tablet with Bosentan may decrease the effectiveness of Denoreg 2 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Denoreg 2 mg Tablet can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DienogestPrimidone
Severe
How does the drug interact with Denoreg 2 mg Tablet:
Taking Denoreg 2 mg Tablet with Primidone may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between primidone and Denoreg 2 mg Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DienogestMycophenolic acid
Severe
How does the drug interact with Denoreg 2 mg Tablet:
Co-administration of Denoreg 2 mg Tablet with Mycophenolic acid may decrease the levels and action of Denoreg 2 mg Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Denoreg 2 mg Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
DienogestPhenytoin
Severe
How does the drug interact with Denoreg 2 mg Tablet:
Taking Phenytoin with Denoreg 2 mg Tablet may reduce the blood levels and effects of Denoreg 2 mg Tablet.

How to manage the interaction:
Although taking Phenytoin and Denoreg 2 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Denoreg 2 mg Tablet as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Denoreg 2 mg Tablet with Grapefruit and Grapefruit juice may increase the side effects of Denoreg 2 mg Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Denoreg 2 mg Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PROGESTIN]

FAQs

DENOREG 2 TABLETS is indicated for the management of painful symptoms of endometriosis, a condition in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.

DENOREG 2 TABLETS suppresses the production of a hormone called estradiol, which causes excess growth of the endometrium. Thereby, DENOREG 2 TABLETS helps in treating pelvic pain associated with endometriosis.

DENOREG 2 TABLETS may cause weight gain. Maintain a healthy weight by exercising regularly. Try eating smaller but more frequent meals. Consult your doctor if you notice severe weight gain.

Do not stop taking DENOREG 2 TABLETS on your own. Continue taking DENOREG 2 TABLETS for as long as your doctor has prescribed it for you, depending on your condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking DENOREG 2 TABLETS .

Avoid using hormonal contraceptives with DENOREG 2 TABLETS ; instead, use non-hormonal contraceptive methods such as condoms or barrier methods. Please consult your doctor; he/she may advise regarding proper contraception.

Antibiotics and antifungal medicines might affect how DENOREG 2 TABLETS works or might be affected by DENOREG 2 TABLETS . Therefore, consult your doctor before taking antibiotics or antifungals with DENOREG 2 TABLETS .

DENOREG 2 TABLETS may cause irregular menstrual bleeding or infrequent periods. Talk to your doctor if you experience this.

Long-term use of DENOREG 2 TABLETS might lower bone mineral density and affect bone health. An adequate intake of calcium and vitamin D, either via your food or supplements, may be helpful.

DENOREG 2 TABLETS should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.

DENOREG 2 TABLETS should be swallowed as a whole with water; do not crush or chew it.

DENOREG 2 TABLETS contains dienogest, which belongs to a group of medicines called progestin and is indicated for the management of endometriosis.

Yes, DENOREG 2 TABLETS is a synthetic steroid.

DENOREG 2 TABLETS helps endometriosis by suppressing the production of a hormone called estradiol, which causes excess growth in the endometrium.

DENOREG 2 TABLETS may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Talk to your doctor if any of the side effects persist or worsen.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

13/1/H/1 Seal\'s Garden Lane, Kolkata, West Bengal, India - 700002
Other Info - DEN0338
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