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compositionComposition:HYDROQUINONE-4%W/W
prescription
Prescription Medicine
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Depi Edge 4%W/W Cream is used to treat melasma (dark brown patch on skin), hyperpigmentation and photoaging. It is a skin-lightening agent that helps even out skin tone and improves skin appearance when used under medical supervision.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HYDROQUINONE-4%W/W

Manufacturer/Marketer :

Derma Edge Pharma Llp

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Depi Edge 4%W/W Cream

Depi Edge 4%W/W Cream is a topical skin-lightening medicine used to fade dark patches of skin. It is medically prescribed to treat skin conditions like melasma, age spots, freckles, and dark marks left behind by acne, pregnancy, or skin injuries. It works by targeting the cells that produce skin colour to help even out your complexion.

For this medicine to work well, you must use it consistently and exactly as directed by your doctor. It is typically applied once or twice daily to clean, dry skin. To help secure the best results, you must wear a high-SPF sunscreen and protective clothing daily, as even minimal sun exposure can reverse the skin-lightening effects.

While using Depi Edge 4%W/W Cream, you might experience mild skin irritation, redness, or a slight burning sensation. These are usually temporary and fade as your skin adjusts. However, if you experience severe skin cracking, bleeding, or an unusual blue-black skin darkening, stop using the product immediately and consult your doctor.

Do not use this medicine if you have a known allergy to any of its ingredients. Before you start using Depi Edge 4%W/W Cream, tell your doctor if you have other skin conditions like eczema or psoriasis, or if you have a history of asthma or severe allergies. This helps ensure the medicine is safe for your skin type.

Avoid using other harsh or drying skin products, such as those containing benzoyl peroxide or strong acids, at the exact same time as Depi Edge 4%W/W Cream to prevent severe skin irritation. If you are pregnant, breastfeeding, or planning to become pregnant, talk to your doctor before using this medicine, as its safety in these groups has not been fully established.

Uses of Depi Edge 4%W/W Cream

Depi Edge 4%W/W Cream is used to fade dark patches of skin. The detailed uses of Depi Edge 4%W/W Cream are as follows:

  • Melasma: Depi Edge 4%W/W Cream helps lighten the dark, patchy brown spots on the face that often occur due to hormonal changes from pregnancy or birth control pills.
  • Hyperpigmentation: Depi Edge 4%W/W Cream reduces stubborn dark patches and uneven skin tone caused by inflammation, acne scars, or minor skin injuries.
  • Age spots and freckles: Depi Edge 4%W/W Cream fades flat, dark spots and freckles caused by chronic sun exposure and natural ageing.
     

Key Benefits

Depi Edge 4%W/W Cream helps reduce hyperpigmentation by decreasing excess melanin production in the skin. With regular use, it helps fade dark spots, improve skin tone, and promote a clearer, more even complexion.

  • Helps Fade Dark Spots: By targeting excess pigmentation, Depi Edge 4%W/W Cream helps reduce the appearance of dark patches and stubborn discolouration, restoring a more even skin tone.
  • Improves Overall Skin Appearance: As pigmentation gradually fades, Depi Edge 4%W/W Cream helps promote smoother, healthier-looking skin with a brighter and more uniform complexion.
  • Supports Long-Term Skin Clarity: With consistent use as directed and appropriate sun protection, Depi Edge 4%W/W Cream helps manage hyperpigmentation and reduces the recurrence of uneven skin tone.
     

Directions for Use

  • Use Depi Edge 4%W/W Cream twice daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Apply the recommended amount of the medicine with clean, dry hands to the affected areas. Gently massage the medicine into the skin with your fingers.
  • Avoid getting it into the eyes or mouth. If contact occurs, rinse it with plenty of water.
  • Wash your hands before and after using Depi Edge 4%W/W Cream.

How Depi Edge 4%W/W Cream Works

Depi Edge 4%W/W Cream contains hydroquinone, which works by limiting the activity of the specific enzyme in your skin cells responsible for producing melanin, which is the natural pigment that gives skin its colour. By slowing down melanin production, the medicine prevents new dark spots from forming. As your old skin cells naturally shed over time and are replaced by new ones, the dark areas gradually fade to match your normal skin tone.
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Alcohol

Consult your doctor

The interaction of Depi Edge 4%W/W Cream with alcohol is unknown. Please consult a physician before consuming alcohol while using Depi Edge 4%W/W Cream.

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Pregnancy

Consult your doctor

Depi Edge 4%W/W Cream is safe to use in pregnant women. However, please consult a physician if you are pregnant before using Depi Edge 4%W/W Cream.

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Breast Feeding

Consult your doctor

Depi Edge 4%W/W Cream is safe to use in breastfeeding women. However, please consult a physician if you are breastfeeding before using Depi Edge 4%W/W Cream.

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Driving

Safe if prescribed

Depi Edge 4%W/W Cream usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Depi Edge 4%W/W Cream is safe in liver patients. If you have any concerns about using Depi Edge 4%W/W Cream in patients with liver problems, please consult a physician.

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Kidney

Consult your doctor

Depi Edge 4%W/W Cream is safe in kidney patients. If you have any concerns regarding the use of Depi Edge 4%W/W Cream in patients with kidney problems, please consult a physician.

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Children

Unsafe

Depi Edge 4%W/W Cream is not recommended for children below 12 years of age.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Depi Edge 4%W/W Cream. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Depi Edge 4%W/W Cream in elderly patients. Please consult your doctor.

What if I have taken an overdose of Depi Edge 4%W/W Cream

Because this medicine is applied topically, a dangerous physical overdose is highly unlikely. However, if you apply too much and experience severe skin irritation, wash the area thoroughly with cold water. If Depi Edge 4%W/W Cream is accidentally swallowed, seek immediate medical attention right away.

Diet & Lifestyle Advise

  • Apply a broad-spectrum sunscreen with an SPF of 30 or higher every single day, even on cloudy days, to protect your healing skin.
  • Wear wide-brimmed hats, sunglasses, and protective clothing to shade your face and neck from direct sunlight when outdoors.
  • Avoid tanning beds and limit your direct sun exposure as much as possible, especially during peak afternoon hours.
  • Stay well-hydrated by drinking plenty of water daily to support your skin's natural healing and barrier repair.
  • Do not pick, scratch, or squeeze acne and healing skin wounds, as physical damage can trigger new dark spots.
     
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How Soon It Starts Working

  • The time required for Depi Edge 4%W/W Cream to start to work: The time required for Depi Edge 4%W/W Cream to show its action is unknown.
  • The time for which the effects of Depi Edge 4%W/W Cream last: The duration of action for Depi Edge 4%W/W Cream is clinically unknown.

What if you forget to take Depi Edge 4%W/W Cream

If you miss an application, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed one and return to your regular routine. Do not apply a double layer of the medicine to make up for a missed application.

Storage

•Store Depi Edge 4%W/W Cream at a stable room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the tube tightly closed immediately after every use to prevent the medicine from oxidising and turning brown.

Drug Warnings

  • Perform a skin patch test before your first full application: apply a tiny amount to an unbroken patch of skin and check for severe redness, itching, or swelling within 24 hours.
  • Always inspect the colour of the cream before applying it; if the cream has turned dark brown or discoloured, discard the tube, as it has likely oxidised and lost its strength.
  • Do not apply this medicine to skin that is sunburnt, windburned, chapped, dry, or irritated.
  • Avoid using harsh chemical peels, hair perms, or alcohol-containing toners on the treated skin areas unless your doctor tells you to.
  • Do not cover the treated skin with bandages, plastic wraps, or tight dressings unless specifically instructed by your doctor.
     

verifiedApollotooltip
  • Topical Peroxides: Using benzoyl peroxide, hydrogen peroxide, or other peroxide products at the same time as Depi Edge 4%W/W Cream on the same skin area may cause temporary, dark staining of the skin. This staining can be washed off easily with soap and water, but it is best to avoid using these products together.
     

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verifiedApollotooltip

No clinically significant food interactions are known with Depi Edge 4%W/W Cream when used as directed. 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Depi Edge 4%W/W Cream is used to treat melasma, hyperpigmentation, dark spots, and photoaging (premature skin ageing caused by repeated exposure to UV radiation).
Depi Edge 4%W/W Cream contains Hydroquinone, a whitening agent that reduces melanin (a chemical that determines the colour of the skin and hair) production, thereby lightening the complexion of the skin.
You are advised to use moisturiser in the morning every day to restore the fat barrier of the skin that protects the skin from damage. Depi Edge 4%W/W Cream may make the skin more sensitive to extreme weather conditions such as cold and wind. Therefore, wear protective clothing and use moisturiser as required. However, please consult a physician before using moisturising lotions or other products with Depi Edge 4%W/W Cream.
Depi Edge 4%W/W Cream is a natural skin-lightening product that reduces melanin production, improves skin tone, texture, and sensitivity, and reduces skin's uneven colour. Using it for some days lightens the appearance of scars.
No, it is not advised to stop using Depi Edge 4%W/W Cream even after your symptoms are relieved. You should complete the full course of treatment. You might see improvement in your symptoms, but the condition might not be cured completely.
Depi Edge 4%W/W Cream can make your skin more sensitive to the harmful effects of sunlight. Hence, it is advised to use sunscreen and protective clothing while using Depi Edge 4%W/W Cream. It is recommended to avoid tanning booths and sunlamps.
It is not recommended to use Depi Edge 4%W/W Cream with benzoyl peroxide, hydrogen peroxide, or any other peroxide products, as it may cause skin staining, which can usually be removed with soap and water. However, please consult a physician before using other medicines with Depi Edge 4%W/W Cream.
Depi Edge 4%W/W Cream is generally considered safe for facial use, being specifically formulated to address melasma, hyperpigmentation, and dark spots. For optimal safety, consulting a dermatologist, following instructions, and conducting a patch test are recommended prior to facial application.
No, Depi Edge 4%W/W Cream does not permanently lighten the skin. It is designed to reduce the appearance of hyperpigmentation, dark spots, and melasma, resulting in a more even skin tone. However, once you stop using the cream, your skin may gradually return to its original tone.
When using Depi Edge 4%W/W Cream, avoid prolonged sun exposure, harsh skin products, exfoliating or scrubbing the treated area, sharing the cream, and applying it to broken or irritated skin. If you're allergic to any ingredients or have sensitive skin, consult a dermatologist before use.
Depi Edge 4%W/W Cream should be applied as directed by your dermatologist or according to the product's instructions. Typically, a thin layer of the product is applied gently to the affected area, once or twice a day. The application frequency and duration may vary depending on the specific skin concern being treated, such as melasma, hyperpigmentation, or dark spots.
Depi Edge 4%W/W Cream is generally considered safe for most skin types when used as directed. However, as with any skincare product, some individuals may experience adverse reactions or side effects. It's essential to follow the recommended usage instructions and consult a dermatologist if you have sensitive skin or concerns.
Common side effects of Depi Edge 4%W/W Cream include dry skin, erythema (skin redness), burning sensation, mild itching, and skin irritation. However, not everyone who uses Depi Edge 4%W/W Cream will experience these side effects. Most of these side effects are temporary and resolve on their own, but if they persist or worsen, consult your physician for guidance.
Yes, you can use makeup. Allow Depi Edge 4%W/W Cream to absorb completely into your skin and dry before applying sunscreen, moisturisers, or cosmetics. Talk to your doctor or pharmacist.
In very rare cases, long-term use can cause a blue-black skin darkening. If you notice any unusual darkening, stop using the medicine immediately and talk to your doctor.
No, Depi Edge 4%W/W Cream is not an overall skin bleacher. It should only be applied directly to the specific dark spots or patches of skin your doctor has prescribed it for. Talk to your doctor.
The safety of Depi Edge 4%W/W Cream during pregnancy is not fully established, as small amounts can be absorbed through the skin. It is usually not recommended unless clearly needed. Talk to your doctor.
Yes, but you must be very cautious. Always perform a small patch test on your arm for 24 hours to check for a severe reaction before applying it to your face. Talk to your doctor.
If the cream turns dark brown, it has oxidised due to air exposure and is no longer effective or safe to use. You should safely discard the tube and talk to your pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

BLOCK - K, UNIT - 1, SAMET BUSINESS PARK, NR. PARISKAR-II, KHOKHRA CIRCLE, AMRAIWA DI, AHMEDABAD Ahmedabad GJ 380008 IN
Other Info - DEP0248

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