Depinor Tabletlet 10's
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About Depinor Tabletlet 10's
Depinor Tabletlet 10's is used to treat depression. Additionally, it is also used to treat neuropathic pain and bedwetting at night. Depression is a mental illness or disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
Depinor Tabletlet 10's contains Nortriptyline, which works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain. These messengers communicate with brain cells, thereby regulating mood and preventing depression. Besides this, Depinor Tabletlet 10's also transmits pain signals. Thus, it provides relief from neuropathic pain.
Take Depinor Tabletlet 10's as prescribed by your doctor. In some cases, you may experience certain common side effects such as increased heart rate, flushing, drowsiness, weight gain, difficulty in urination, orthostatic hypotension (sudden lowering of blood pressure on standing), dryness in the mouth, tingling in the arms or legs, blurred vision (dilated pupils). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
To treat your condition effectually, continue taking Depinor Tabletlet 10's for as long as your doctor has prescribed. Inform your doctor if you have suicidal ideation or behaviour symptoms, heart disease, seizure disorders, glaucoma, thyroid problems, or kidney and liver problems. Do not take Depinor Tabletlet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. The safety and effectiveness in children less than 18 years of age have not been established, so Depinor Tabletlet 10's should not be given to them. Avoid consuming alcohol along with Depinor Tabletlet 10's as it could lead to increased drowsiness and dizziness. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Rise slowly from sitting or lying position as Depinor Tabletlet 10's causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of Depinor Tabletlet 10's
Depinor Tabletlet 10's is used for the treatment of depression, and neuropathic pain. The detailed uses of Depinor Tabletlet 10's are as follows:
- Depression Treatment: Depinor Tabletlet 10's is used to treat major depressive disorder by balancing neurotransmitters in the brain, which helps improve mood and relieve depression symptoms.
- Anxiety Disorders: Depinor Tabletlet 10's is also used to manage anxiety disorders, reducing symptoms of generalized anxiety, panic attacks, and other related conditions by promoting relaxation and mental well-being.
- Chronic Pain Management: Depinor Tabletlet 10's is used to manage chronic pain, particularly neuropathic pain conditions such as fibromyalgia and diabetic neuropathy, by changing how the brain processes pain signals.
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Directions for Use
- It can be taken with or without food as advised by a doctor.
- Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
- Swallow Depinor Tabletlet 10's as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
Depinor Tabletlet 10's belongs to a group of medicines called tricyclic antidepressants used to prevent depression. It works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby helping regulate mood and treat depression. Depinor Tabletlet 10's prevents the transmission of pain signals, thereby providing relief from neuropathic pain.
How Depinor Tabletlet 10's Works
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What if I have taken an overdose of Depinor Tabletlet 10's
Drug Warnings
Do not take Depinor Tabletlet 10's if you are known to be allergic to Depinor Tabletlet 10's. Inform your doctor if you have suicidal ideation or behaviour symptoms, have heart rhythm problems or hypotension, heart disease, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, kidney and liver problems. Do not take Depinor Tabletlet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Depinor Tabletlet 10's should not be given to children less than 18 years of age, as its safety and efficacy have not been established. Avoid consuming alcohol along with Depinor Tabletlet 10's as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Depinor Tabletlet 10's causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Depinor Tab with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.
How to manage the interaction:
Taking Depinor Tab with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Depinor Tab with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.
How to manage the interaction:
Taking Depinor Tab with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Co-administration of Depinor Tab with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).
How to manage the interaction:
Taking Depinor Tab with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Depinor Tab with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).
How to manage the interaction:
Taking Depinor Tab with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
Using Depinor Tab together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).
How to manage the interaction:
Taking Isocarboxazid with Depinor Tab is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Depinor Tab with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).
How to manage the interaction:
Taking Depinor Tab with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
Coadministration of Depinor Tab with Ziprasidone can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Depinor Tab with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
Coadministration of Depinor Tab with Pimozide can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Depinor Tab with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
Coadministration of Depinor Tab with Nilotinib can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Depinor Tab with Nilotinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
Coadministration of Depinor Tab with Cabozantinib can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Depinor Tab with Cabozantinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Maintaining a healthy diet and exercising regularly helps improve overall health and boosts self-esteem.
- Regularly attend therapy sessions.
- Perform meditation and yoga. This helps in relieving stress and provides relaxation.
- Follow a regular sleep pattern to improve the amount and quality of sleep you get.
- Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
- Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitters properly.
- Complex carbohydrates help stimulate serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
- Exercising helps produce the body’s natural antidepressants. It also relieves stress, improves mood, boosts self-esteem, and provides restful sleep.
- Avoid smoking and alcohol consumption.
- Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.
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Alcohol
Unsafe
Avoid consumption of alcohol while taking Depinor Tabletlet 10's as it may cause an increased sedative effect. Please consult a doctor before consuming alcohol with Depinor Tabletlet 10's.
Pregnancy
Consult your doctor
Avoid taking Depinor Tabletlet 10's if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Consult your doctor before taking Depinor Tabletlet 10's; your doctor will decide whether breastfeeding mothers can take Depinor Tabletlet 10's or not.
Driving
Unsafe
Depinor Tabletlet 10's may affect your ability to drive or operate machinery safely. Therefore, drive only if you are alerted after taking the Depinor Tabletlet 10's.
Liver
Caution
Take Depinor Tabletlet 10's with caution, especially if you have a history of liver disease/conditions. Your doctor may adjust the dose as required.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Depinor Tabletlet 10's is not recommended for children under 18 years of age. Its safety and efficacy have not been established.
Heart
Caution
Caution should be exercised while taking Depinor Tabletlet 10's in cardiac patients, as it can cause side effects like orthostatic hypotension.
Geriatrics
Safe if prescribed
Depinor Tabletlet 10's is safe for use in elderly patients if prescribed by the physician.
FAQs
Depinor Tabletlet 10's is used to treat depression. Additionally, it is also used to treat neuropathic pain and bedwetting at night.
Depinor Tabletlet 10's contains Nortryptaline, which works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain that communicate between brain cells. Thus, it helps regulate mood and treats depression.
Do not take Depinor Tabletlet 10's if you are allergic to antidepressants (like nortriptyline, amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, protriptyline, trimipramine), antiallergic (like carbamazepine, eslicarbazepine, oxcarbazepine and rufinamide), and MAO inhibitors (like isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others). Besides this, if you have used an SSRI antidepressant in the last 5 weeks like escitalopram, fluoxetine, citalopram, fluvoxamine, paroxetine, sertraline, trazodone, or vilazodone let your doctor know about this.
No, you should not take Depinor Tabletlet 10's if you have had a recent heart attack or stroke. Taking Depinor Tabletlet 10's after a heart attack can worsen your present health conditions Unless your doctor thinks the benefits outweigh the risks.
In some cases, Depinor Tabletlet 10's could make your skin sensitive and sunburn more easily. So, it is advisable to avoid sunlight or tanning beds. You can also wear protective clothing and use sunscreen (SPF 30 or more) when outside.
The common side effects of Depinor Tabletlet 10's include dizziness, blurred vision, headache, trouble with eye focusing, vision problems, constipation, dry mouth, high heartbeat (heart palpitation), tiredness, low blood pressure (especially on standing). Prolonged intake of Depinor Tabletlet 10's may increase the risk of eye pressure and heart attack. So, if you experience any of these symptoms immediately contact a doctor.
Depinor Tabletlet 10's could increase the pressure in your eyes. If you have a history of glaucoma or increased eye pressure, your doctor will monitor you more closely while you take nortriptyline.
No, If you have bipolar disorder that is not being treated, taking nortriptyline can make your condition worse.
Take the Depinor Tabletlet 10's as prescribed by your doctor. You can take it with or without food. Depinor Tabletlet 10's can make you feel sleepy. So it’s best to take it in the evening or before you go to bed. Swallow it whole with water. Do not crush, chew, or break it.
No, you should not stop taking Depinor Tabletlet 10's even if your pain is relieved, as it can lead to withdrawal symptoms such as nausea, headache, and weakness. It's important to consult your doctor before stopping Depinor Tabletlet 10's.
Maintain a healthy weight by focusing on a diet rich in fruits, vegetables, whole grains, and lean proteins, avoiding sugary foods, and by engaging in regular exercise. If you still have any concerns, discuss with your doctor.
The serious side effects of Depinor Tabletlet 10's include fast and irregular heartbeat, yellowing of eyes or skin, persistent headaches, confusion, muscle cramps, eye pain, eye swelling, and persistent constipation. If you experience any of these side effects, please consult your doctor immediately.
The onset of action for Depinor Tabletlet 10's can vary depending on the condition being treated. For depression, it typically takes 4 to 6 weeks to show full effect and for nerve pain, you may start to notice improvement within 1 to 3 weeks. Do not stop taking Depinor Tabletlet 10's after 1 or 2 weeks if you feel it’s not helping your symptoms. Give it at least 6 weeks to work. However consult your doctor if you have any concerns.
Take the Depinor Tabletlet 10's as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dose. Do not take a double dose to make up for a missed one.
Taking too much nortriptyline can cause overdose and result in symptoms such as irregular heartbeat, hallucinations, widened pupils, drowsiness, fever, vomiting, confusion, muscle stiffness, or seizures (fits). If these side effects persist or worsen, please consult your doctor immediately.
Avoid drinking alcohol while taking Depinor Tabletlet 10's as it may increase sleepiness or affect your alertness or concentration. Some medications should not be taken with Depinor Tabletlet 10's, discuss with your doctor before taking Depinor Tabletlet 10's and you should also avoid foods high in tyramine. These include aged cheeses, cured meats (like salami and pepperoni), and fermented foods.
While taking Depinor Tabletlet 10's, you should follow your doctor's advice regarding follow-up appointments. However consult your doctor immediately, if you experience any side effects.
Yes, Depinor Tabletlet 10's can cause sleepiness or drowsiness as a side effect, especially when you first start taking the medication. This side effect may decreases as your body adjusts to the medication, but if it persists or worsens, please consult your doctor.
No, taking Depinor Tabletlet 10's more than recommended will not increase its effectiveness. Instead, it can lead to severe side effects and toxicity, such as confusion, seizures, rapid heart rate, and potentially life-threatening conditions. It's important to take Depinor Tabletlet 10's in dosage prescribed by your doctor if you feel your current dose is not working effectively, consult your doctor.
Store Depinor Tabletlet 10's at room temperature in a dark and dry place. Keep it out of reach of children.
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