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Depishine-TX Tablet is used to control bleeding in conditions like menorrhagia (heavy or prolonged menstrual bleeding) and nose bleeds. It works by preventing the breakdown of fibrin (a protein that is involved in blood clotting), thereby, it helps prevent bleeding. Besides this, it also exerts anti-inflammatory properties. In some cases, this medicine may cause side effects like nausea, diarrhoea, and itchy red skin.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Livia Healthcare Llp

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Depishine-TX Tablet

Depishine-TX Tablet is an oral medicine primarily prescribed to treat melasma, hyperpigmentation, and uneven skin tone. It works by reducing the biological signals that trigger excess melanin (skin pigment) production, helping fade existing dark patches and reduce the formation of new ones. Doctors commonly recommend this treatment for stubborn pigmentation caused by sun exposure or hormonal changes.

To achieve the best results, you must take Depishine-TX Tablet consistently at the same time every day as directed by your doctor. This medicine can be taken with or without food, though taking it with a meal may help prevent mild stomach upset. Combining this treatment with strict sun protection, such as applying sunscreen daily and wearing protective clothing, is essential to see visible improvements.

While taking Depishine-TX Tablet , some people may experience mild side effects like nausea, stomach discomfort, or minor headaches. These symptoms are usually temporary and resolve on their own as your body adjusts. However, if you notice any unusual chest pain, shortness of breath, or changes in your vision, stop taking the medicine immediately and consult your doctor.

Before starting Depishine-TX Tablet , inform your doctor if you have a history of blood clots, kidney problems, or active circulation disorders. Do not take this medicine if you have a known history of deep vein thrombosis, pulmonary embolism, or if you are currently using certain blood-clotting medications. It is also not suitable for individuals with severe kidney impairment.

Avoid consuming alcohol and smoking while taking Depishine-TX Tablet , as they can alter your blood circulation and increase the risk of vascular complications. This medicine may also interact with hormonal contraceptives or blood thinners, potentially increasing the risk of blood clots. Pregnant or breastfeeding women, as well as elderly individuals, must consult their doctor before using this medication to ensure it is safe for them.

Uses of Depishine-TX Tablet

Depishine-TX Tablet used in the treatment of Menorrhagia and Nose bleeding. The detailed uses of Depishine-TX Tablet are as follows:

  • Melasma: Depishine-TX Tablet helps reduce the appearance of dark, symmetrical patches on the face by controlling the pathways that trigger excess melanin production.
  • Hyperpigmentation: This medicine helps fade dark spots, age spots, and post-inflammatory skin darkening caused by sun damage or skin injuries.
  • Uneven skin tone: Depishine-TX Tablet aids in restoring a more uniform skin complexion by regulating pigment distribution across the skin cells.

Key Benefits

Depishine-TX Tablet provides targeted relief from stubborn skin darkening, helping to restore your skin's natural tone and boost your confidence. Unlike topical treatments that only work on the skin's surface, this oral medication works from within to address the root causes of pigment overproduction. Benefits may include:

  • Fades stubborn dark spots: It gradually lightens deep-seated pigmentation that topical creams may fail to reach.
  • Improves skin uniformity: It promotes a more balanced and even complexion across the face and body.
    Convenient oral administration: It offers an easy-to-use systemic approach to skin care, eliminating the need for messy, irritating topical applications.
  • Prevents new pigmentation: It helps protect the skin from developing new dark spots triggered by UV exposure and hormonal fluctuations.
     
Side effects of Depishine-TX Tablet
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Depishine-TX Tablet can be taken with or without food, as advised by your doctor.
  • It is usually taken 3 times a day or as prescribed by your doctor.
  • Swallow the whole Depishine-TX Tablet with a glass of water.
  • Do not break, chew, or crush it.

How Depishine-TX Tablet Works

Depishine-TX Tablet contains Tranexamic acid and Pine bark extract. Tranexamic acid works by blocking the binding of plasminogen to skin cells (keratinocytes). This reduces the release of chemical messengers, including arachidonic acid and prostaglandins. As a result, excess melanin production is reduced, helping existing dark patches gradually fade while reducing the formation of new pigmentation. Pine bark extract is a natural antioxidant that helps protect skin cells from damage caused by free radicals generated by sunlight and pollution. It may also help reduce inflammation and support healthy skin.
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Alcohol

Caution

No interaction was found. However, it is best to avoid alcohol while taking medication as a precautionary measure.

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Pregnancy

Caution

There are no adequate and well-controlled pregnancy studies. Your doctor will only prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Tranexamic acid may be present in trace concentrations in breast milk. However, please consult a doctor if you are a breastfeeding mother.

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Driving

Caution

Depishine-TX Tablet will not impair your ability to drive or operate machines. However, do not drive if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Safe if prescribed

Depishine-TX Tablet is probably safe in patients with liver diseases. Consult your doctor for further advice if you have any concerns about this.

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Kidney

Caution

Depishine-TX Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Limited information is available for the use of Depishine-TX Tablet in pediatric patients. Your doctor will prescribe only if the benefits outweigh the risks.

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Heart

Caution

Depishine-TX Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Caution

Limited data is available regarding the use of Depishine-TX Tablet in elderly patients. If you have any concerns about the usage of Depishine-TX Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Depishine-TX Tablet

In case of an accidental overdose, seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include severe dizziness, nausea, vomiting, or visual disturbances. Do not wait for symptoms to worsen before seeking help.

Diet & Lifestyle Advise

  • Wear broad-spectrum sunscreen daily: Apply a sunscreen with an SPF of 30 or higher every day, even when it is cloudy or if you are indoors, as UV rays trigger pigment production.
  • Use physical sun barriers: Wear wide-brimmed hats, sunglasses, and seek shade during peak sunlight hours to protect your skin from direct exposure.
  • Eat antioxidant-rich foods: Incorporate berries, leafy greens, nuts, and citrus fruits into your diet to help fight free radicals and support skin health.
  • Stay well-hydrated: Drink plenty of water throughout the day to keep your skin hydrated and assist your body in flushing out toxins.
  • Avoid harsh skincare products: Steer clear of abrasive scrubs or skincare products that cause irritation, as inflammation can worsen hyperpigmentation.
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How Soon It Starts Working

The time required for Depishine-TX Tablet to start to work: Depishine-TX Tablet ideally shows its action within 1 to 2 hours of administration. The time for which the effects of Depishine-TX Tablet last: Depishine-TX Tablet effect lasts for 6 to 8 hours.

What if you forget to take Depishine-TX Tablet

If you miss a dose of Depishine-TX Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Depishine-TX Tablet in a cool, dry place at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Check the packaging: Inspect the blister pack or bottle before use; do not take the medication if the seal is broken or the tablets appear damaged or discolored.
  • Watch for visual changes: Stop taking the medicine immediately and consult an eye specialist if you experience any changes in your vision, as this requires prompt evaluation.
  • Be aware of blood clot risks: Seek emergency medical care if you experience sudden leg pain, swelling, or unexplained shortness of breath.
  • Inform your surgical team: If you have an upcoming surgery or dental procedure, tell your surgeon that you are taking Depishine-TX Tablet , as you may need to stop taking it temporarily to prevent clotting complications.
  • Monitor your kidneys: If you have mild kidney issues, your doctor may monitor your kidney function periodically while you are on this medicine.

Drug-Drug Interactions

verifiedApollotooltip
  • Hormonal contraceptives (birth control pills, patches, or rings): Taking these alongside Depishine-TX Tablet can significantly increase the risk of blood clots.
  • Blood thinners (anticoagulants): Using these medications together may cause conflicting effects on your blood's clotting ability.
  • Clot-dissolving medicines (thrombolytics): These can oppose the action of Depishine-TX Tablet , reducing its effectiveness.
Tranexamic acidEtonogestrel
Critical

Drug-Drug Interactions

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Tranexamic acidEtonogestrel
Critical
How does the drug interact with Depishine-TX Tablet:
Co-administration of Depishine-TX Tablet may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Depishine-TX Tablet with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
How does the drug interact with Depishine-TX Tablet:
Taking Ethinylestradiol with Depishine-TX Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Depishine-TX Tablet is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Depishine-TX Tablet:
Taking Medroxyprogesterone acetate with Depishine-TX Tablet may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Depishine-TX Tablet is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
How does the drug interact with Depishine-TX Tablet:
Taking Levonorgestrel with Depishine-TX Tablet may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Depishine-TX Tablet with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Depishine-TX Tablet:
Taking drospirenone with Depishine-TX Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Depishine-TX Tablet with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidConjugated Estrogens
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Conjugated estrogen with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Conjugated estrogen with Depishine-TX Tablet may result in interaction, it can be taken only if your doctor has advised it. However, if you experience chest pain, shortness of breath, coughing up blood, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depishine-TX Tablet:
Co-administration of Carfilzomib with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking carfilzomib with Depishine-TX Tablet is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidChlorotrianisene
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Chlorotrianisene with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking chlorotrianisene with Depishine-TX Tablet is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depishine-TX Tablet:
Co-administration of tretinoin with Depishine-TX Tablet may increase the risk of blood clots.

How to manage the interaction:
Taking tretinoin with Depishine-TX Tablet is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Depishine-TX Tablet:
Co-administration of tamoxifen with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Although taking tamoxifen and Depishine-TX Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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  • Alcohol: Consuming alcohol while taking this medicine can affect your blood pressure and circulation, increasing the risk of dizziness and other vascular side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIHEMORRHAGIC AGENTS]

FAQs

Depishine-TX Tablet is used to control bleeding, especially for menorrhagia (menstrual bleeding lasts longer than seven days) and nose bleeds.
Depishine-TX Tablet contains tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. This aids in the retention of blood clots in areas where they are required. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with hemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.
Caution should be exercised while using Depishine-TX Tablet in patients with pulmonary embolism (blocked blood vessels in your lungs). Let your doctor know about your present health condition before taking Depishine-TX Tablet .
If you get diarrhoea after using the Depishine-TX Tablet , drink plenty of water to avoid dehydration. If it persists, consult your doctor. Without a doctor's prescription, do not attempt to take antidiarrheal medication.
Depishine-TX Tablet is usually used for a short time to treat bleeding. You are recommended to take Depishine-TX Tablet for as long as it is prescribed by a doctor to treat heavy periods. If you notice no improvement, please consult your doctor.
Yes, Depishine-TX Tablet is used to control excessive bleeding during heavy menstrual periods. However, please consult your doctor before taking Depishine-TX Tablet .
Depishine-TX Tablet may cause gastrointestinal side effects, including loose stools or diarrhoea, in some individuals. However, this is not a universal experience and may vary depending on individual tolerance and sensitivity. Consult your healthcare professional for guidance if you experience persistent or severe loose stools.
The common side effects of Depishine-TX Tablet are nausea (feeling sick), diarrhoea, itchy red skin, stomach upset and headache. Please consult your doctor if any of these side effects persist or worsen.
Depishine-TX Tablet should be used with caution in pregnant women only if prescribed by the doctor. Therefore, inform your doctor immediately if you become pregnant or think you may be pregnant before taking Depishine-TX Tablet . Your doctor will only prescribe if the benefits outweigh the risks.
Yes, you can take Depishine-TX Tablet with or without food. However, if you experience mild stomach discomfort or nausea, taking it with a meal can help ease these symptoms. Talk to your doctor or pharmacist if stomach irritation persists.
Depishine-TX Tablet is generally safe when taken for the duration prescribed by your doctor. However, long-term use should be carefully monitored by a healthcare professional to check for any underlying safety concerns. Talk to your doctor to determine the appropriate treatment duration for you.
Depishine-TX Tablet is highly effective at fading and controlling melasma, but it does not cure the underlying condition permanently. Melasma can return if your skin is exposed to direct sunlight or hormonal triggers without protection. Talk to your doctor about a long-term maintenance plan.
If you notice any changes in your vision, such as blurriness or difficulty distinguishing colors, stop taking Depishine-TX Tablet immediately. Contact your doctor or seek emergency medical attention right away. Talk to your doctor before restarting any similar treatment.
Yes, many doctors recommend combining oral Depishine-TX Tablet with topical treatments like vitamin C, retinoids, or sunscreen for enhanced results. However, you should always consult your dermatologist before combining new treatments. Talk to your doctor to create a safe skincare regimen.
When used for melasma, Depishine-TX Tablet is usually prescribed at lower doses than those used to control bleeding. It does not create new blood clots. However, because tranexamic acid affects the body's clot breakdown process, it may increase the risk of clot-related complications in people with a history of blood clots or other risk factors, such as the use of hormonal contraceptives. Your doctor will assess whether this medicine is suitable for you before starting treatment. Talk to your doctor immediately if you develop symptoms such as sudden leg swelling, chest pain, or shortness of breath.

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Country of origin

India

Manufacturer/Marketer address

Level 17, Dlh Park, Ramlal Compound, Swami Vivekananda Rd, Goregaon West, Mumbai, Maharashtra 400064
Other Info - DEP0228
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