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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Deriphyllin Injection is used to prevent and treat asthma and chronic obstructive pulmonary disease (COPD) symptoms. It contains Theophylline and Etofylline, which relax muscles and widen the lungs' airways. Thus, it makes breathing easier. Thereby, it helps prevent and treat the symptoms of asthma and COPD. Common side effects of Deriphyllin Injection are nausea, vomiting, headache, restlessness, dizziness, or stomach upset.

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Synonym :

THEOPHYLLINE+ETOFYLLINE NICOTINATE

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Deriphyllin Injection

Deriphyllin Injection belongs to the class of drugs called bronchodilators, which are used to prevent and treat asthma and chronic obstructive pulmonary disease (COPD) symptoms. Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Deriphyllin Injection contains Theophylline and Etofylline, which work by relaxing muscles and widening the airways of the lungs. Thus, they make breathing easier. Thereby, Deriphyllin Injection helps prevent and treat the symptoms of asthma and COPD.

Deriphyllin Injection will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience nausea, vomiting, headache, restlessness, dizziness, or stomach upset. Most of these side effects of Deriphyllin Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Deriphyllin Injection or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Deriphyllin Injection . If your breathing worsens or you often wake up at night with asthma and experience chest tightness in the morning, please consult a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment.

Uses of Deriphyllin Injection

Deriphyllin Injection is used to treat Asthma and Chronic Obstructive Pulmonary Disease (COPD) symptoms. The detailed uses of Deriphyllin Injection are as follows:
• Asthma: It is typically used to treat symptoms like coughing, wheezing, and shortness of breath by relaxing the muscles around the airways and improving airflow.
• Chronic Obstructive Pulmonary Disease (COPD): It helps manage COPD by opening up the airways, improving lung function, and alleviating breathing difficulties.
• Breathing Difficulty Relief: It aids in reducing symptoms of shortness of breath and wheezing, making breathing easier, especially in acute situations.
• Short-term Use in Exacerbations: It is generally used in hospital settings during acute flare-ups or when oral or inhaled therapy is not possible. It may not be recommended for long-term or routine use.

Directions for Use

  • Deriphyllin Injection is administered only in clinical settings by healthcare professionals, usually through slow intravenous or intramuscular injection.
  • The doctor carefully determines the dosage and frequency based on the severity of symptoms and the patient's response to treatment. 
  • Do not self-administer this injection, as improper use may lead to serious side effects such as rapid heartbeat, low blood pressure, or seizures.
  • Patients are monitored during and after administration for adverse reactions to ensure safe, effective treatment.

Medicinal Benefits

Deriphyllin Injection contains Theophylline and etofylline, bronchodilators used to treat asthma and chronic obstructive pulmonary disease (COPD) symptoms. Deriphyllin Injection works by relaxing muscles and widening the airways of the lungs, making breathing easier.

How Deriphyllin Injection Works

Deriphyllin Injection contains Theophylline and Etofylline, that works by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier. Thereby, Deriphyllin Injection helps prevent and treat the symptoms of asthma and COPD.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Deriphyllin Injection

As Deriphyllin Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or you are experiencing any adverse events, get medical care right away.

Drug Warnings

Please tell your doctor if you are allergic to Deriphyllin Injection or any other medicines. If your breathing worsens or you often wake up at night with asthma, and experience chest tightness in the morning, please inform a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Deriphyllin Injection as it may cause low potassium levels in the blood. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Deriphyllin Injection . 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Deriphyllin Injection 7x2 ml:
Co-administration of Deriphyllin Injection 7x2 ml with Riociguat can increase the risk of low blood pressure.

How to manage the interaction:
Taking Deriphyllin Injection 7x2 ml with Riociguat is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Taking deferasirox with Deriphyllin Injection 7x2 ml may significantly increase the blood levels of Deriphyllin Injection 7x2 ml.

How to manage the interaction:
Although taking deferasirox and Deriphyllin Injection 7x2 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, diarrhea, loss of hunger, headache, shaking, confusion, restlessness, sleeplesness, fits, heart palpitations, and/or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Taking carvedilol with Deriphyllin Injection 7x2 ml, could make carvedilol less effective and increase the effects of Deriphyllin Injection 7x2 ml.

How to manage the interaction:
Although Carvedilol and Deriphyllin Injection 7x2 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, restlessness, palpitations, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Using propranolol together with Deriphyllin Injection 7x2 ml makes the propranolol less effective in controlling blood pressure, and it also increases the effects of Deriphyllin Injection 7x2 ml

How to manage the interaction:
Although taking Propranolol together with Deriphyllin Injection 7x2 ml can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Taking fluvoxamine with Deriphyllin Injection 7x2 ml may significantly increase the blood levels of Deriphyllin Injection 7x2 ml.

How to manage the interaction:
Although taking fluvoxamine and Deriphyllin Injection 7x2 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, diarrhea, loss of hunger, headache, shaking of hands and legs, confusion, restlessness, insomnia, fits, heart palpitations, or irregular heartbeat. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Taking sotalol with Deriphyllin Injection 7x2 ml, could reduce sotalol effects and increase the effects of Deriphyllin Injection 7x2 ml.

How to manage the interaction:
Although taking sotalol and Deriphyllin Injection 7x2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Coadministration of Nebivolol with Deriphyllin Injection 7x2 ml may reduce the effect of Nebivolol.

How to manage the interaction:
Taking Nebivolol with Deriphyllin Injection 7x2 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Co-administration of tramadol with Deriphyllin Injection 7x2 ml can increase the effect of tramadol.

How to manage the interaction:
Taking Deriphyllin Injection 7x2 ml with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Taking esmolol with Deriphyllin Injection 7x2 ml, could make esmolol less effective and enhance the effects of Deriphyllin Injection 7x2 ml.

How to manage the interaction:
Although taking esmolol and Deriphyllin Injection 7x2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Deriphyllin Injection 7x2 ml:
Taking Metoprolol Tartrate with Deriphyllin Injection 7x2 ml could make Metoprolol Tartrate less effective and increase the side effects of Deriphyllin Injection 7x2 ml

How to manage the interaction:
Although taking metoprolol tartrate and Deriphyllin Injection 7x2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in potassium, such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots. Potassium is important for lung function, and a deficiency may cause breathing problems.
  • Drink plenty of fluids as it thins the mucus and makes it easier to cough up.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled foods, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice, as they may worsen asthma symptoms.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of Deriphyllin Injection , irritate the lungs or worsen breathing problems.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR
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Alcohol

Caution

The interaction of Deriphyllin Injection with alcohol is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Caution

If you are pregnant, inform your doctor before receiving Deriphyllin Injection . Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Deriphyllin Injection is excreted in human milk. Therefore, please inform your doctor if you are breastfeeding before receiving Deriphyllin Injection .

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Driving

Caution

Drive only if you are alert after taking Deriphyllin Injection as it may cause dizziness in some people.

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Liver

Caution

Deriphyllin Injection should be taken with caution if you have liver problems. Your doctor may adjust the dose as required. Deriphyllin Injection should not be used if you have severe liver disease.

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Kidney

Caution

Deriphyllin Injection should be taken with caution in case of renal disease. Your doctor may adjust the dose as required. Deriphyllin Injection should not be used if you have severe kidney disease.

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Children

Caution

Limited information is available on the usage of Deriphyllin Injection in children. Please discuss this with a doctor if you have any concerns.

Have a query?

FAQs

Deriphyllin Injection belongs to the class of drugs called bronchodilators, which are used to prevent and treat asthma and chronic obstructive pulmonary disease (COPD) symptoms.

Deriphyllin Injection works by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier.

You are recommended to consult a doctor before taking ciprofloxacin or other medicines with Deriphyllin Injection .

You are recommended to avoid taking Deriphyllin Injection if you are allergic to theophylline, and etofylline or are suffering from irregular heart rhythm, severe liver or kidney diseases or have a history of a heart attack. Inform your doctor if you have any of these conditions before taking Deriphyllin Injection .

Deriphyllin Injection does not relieve sudden asthma symptoms. Therefore, it is advised to always carry a rescue inhaler to treat sudden asthma symptoms.

Deriphyllin Injection belongs to the group of medications called bronchodilators. It primarily treats asthma and chronic obstructive pulmonary disease (COPD) symptoms. It comprises theophylline and etofylline, which help relieve breathlessness by relaxing the airway muscles, making it easier to inhale and exhale. It also reduces the lungs' sensitivity to irritants, effectively managing breathing problems and enabling a person to lead a normal life.

Yes, Deriphyllin Injection may cause insomnia, as it contains active ingredients that can stimulate the central nervous system. If you notice difficulty sleeping or other disruptions to your sleep patterns while using this medication, consult the doctor to discuss your symptoms, as they may need to adjust your treatment plan or provide additional guidance.

Yes, high doses of Deriphyllin Injection may lead to an overdose of medication that causes severe side effects, including slow heart rate, seizure, nausea, and vomiting. If you experience any of these symptoms, consult the doctor immediately.

The side effects of Deriphyllin Injection include restlessness, headaches, irritability, sleeplessness, difficulty sleeping, and falling asleep. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - DER0560

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