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compositionComposition:ADAPALENE-0.1%W/W
prescriptionPrescription Medicine
Deriva MS Aqueous Gel 15 gm
Deriva MS Aqueous Gel 15 gm
Deriva MS Aqueous Gel 15 gm

Deriva MS Aqueous Gel is used to treat acne (pimples) in patients aged 12 years and older. It helps reduce pimples, blackheads, and whiteheads. Regular use helps maintain clear skin and prevents new breakouts. It also improves skin texture and appearance over time.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ADAPALENE-0.1%W/W

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Deriva MS Aqueous Gel

Deriva MS Aqueous Gel is used to treat acne (pimples) in patients 12 years or older. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feed on sebum (natural oil produced by the skin), leading to redness and swelling.

Deriva MS Aqueous Gel contains Adapalene, which works by loosening the cells on the skin’s surface and unblocking pores by reducing oil production. Thus, it decreases pimples, whiteheads, and blackheads.

Use Deriva MS Aqueous Gel as prescribed. You may experience dry skin, irritation, redness, or a burning sensation of the skin in some cases. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

If you are known to be allergic to Deriva MS Aqueous Gel or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Deriva MS Aqueous Gel. If you have eczema (itchy, swollen, rough, and cracked skin), skin cancer or sunburn, please inform your physician before taking Deriva MS Aqueous Gel.

Uses of Deriva MS Aqueous Gel

Deriva MS Aqueous Gel is used in the treatment of acne (pimples). The detailed uses of Deriva MS Aqueous Gel are as follows:

  • Treats Acne: Deriva MS Aqueous Gel helps reduce pimples, whiteheads, and blackheads by loosening dead skin cells and unblocking clogged pores, thereby reducing oil production in the skin.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Wash the affected area with water and dry it thoroughly. Apply a thin layer of Deriva MS Aqueous Gel to clean, dry skin at night, or as directed by your physician.
  • Deriva MS Aqueous Gel is for external use only.
  • Wash your hands before and after applying Deriva MS Aqueous Gel.

Key Benefits

  • Helps reduce pimples, whiteheads, and blackheads.
  • Unblocks clogged pores and controls excess oil.
  • Promotes natural shedding of dead skin cells.
  • Supports the formation of fresh, healthy skin.
  • Helps reduce redness, swelling, and irritation.
  • Improves overall skin comfort during acne treatment.

How Deriva MS Aqueous Gel Works

Deriva MS Aqueous Gel contains Adapalene, which works by loosening the cells on the skin's surface and unblocking pores by reducing oil production. Thus, it decreases pimples, whiteheads, and blackheads.

Storage

Store in a cool and dry place away from sunlight
Side effects of Deriva MS Aqueous Gel 15 gm
  • After taking a shower or bath, apply a moisturizer to damp skin.
  • Use petroleum jelly or other thick emollients.
  • Use a hypoallergenic, fragrance-free moisturizer 2 to 3 times a day or as frequently as required.
  • Exfoliate your skin gently using a pumice stone or slightly abrasive sponge.
  • Do not scrub your skin.
  • Avoid hot showers or baths. Instead take short, warm showers or baths.
  • Use mild soap or skin cleansers with added moisturizer.
  • Drink lots of water.
  • Use sunscreen and wear protective clothing while going out to protect yourself from sun damage.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid extreme heat or cold, like hot showers or cold winds, to prevent worsening skin discomfort.
  • Cool compresses: To reduce itch, redness, and swelling.
  • Avoid irritants like harsh chemicals or allergens to prevent worsening skin discomfort.
  • If you have severe itching, burning, or blistering seek medical attention.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Sunburns can occur commonly. Cover the area that is affected to avoid extended exposure.
  • Apply a clean, dampened towel to the affected skin for relief.
  • Take a cool bath by adding baking soda to water.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet that heals the allergy or burns.
  • Apply a skin-calming lotion, gel or moisturiser frequently.

What if I have taken an overdose of Deriva MS Aqueous Gel

Do not apply Deriva MS Aqueous Gel in large amounts or for longer than recommended, as it does not yield quick or improved results and may cause adverse effects. The symptoms of adverse effects include skin irritation, scaling and redness. If you suspect you have used more or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • If you are known to be allergic to Deriva MS Aqueous Gel or any other medicines, please tell your doctor.
  • Do not apply Deriva MS Aqueous Gel on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Avoid contact of Deriva MS Aqueous Gel with nose, ears, mouth, or eyes.
  • If Deriva MS Aqueous Gel comes into contact with these areas accidentally, rinse thoroughly with warm water.
  • Avoid exposure to tanning beds or sunlight while using Deriva MS Aqueous Gel, as it may increase skin sensitivity to sunlight and cause sunburn.
  • Wear protective clothing and use sunscreen when outdoors to prevent sunburn.
  • If you are pregnant or breastfeeding, please inform your doctor before taking Deriva MS Aqueous Gel.
  • Do not apply Deriva MS Aqueous Gel in large amounts or for longer than prescribed, as it does not yield rapid or improved results and increases the risk of side effects, including skin irritation, scaling, or redness.
  • You are advised not to use other acne products containing erythromycin, benzoyl peroxide, or clindamycin with Deriva MS Aqueous Gel at the same time, as it may cause excessive irritation or dry skin. Therefore, it is recommended to use Deriva MS Aqueous Gel at night and other products in the morning.
  • If you have eczema (itchy, swollen, rough, and cracked skin) or sunburn, please inform your physician before taking Deriva MS Aqueous Gel.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Sun Protection:

  • Avoid direct sun exposure as Deriva MS Aqueous Gel can make the skin more sensitive.
  • Wear protective clothing and use sunscreen when going outdoors.

Exercise & Hygiene:

  • Exercise regularly to support mood and confidence.
  • Take a shower soon after exercise to remove sweat that may irritate acne.

Hair Care:

  • Wash hair regularly and keep it away from the face.
  • Avoid letting oily hair touch the skin.

Skin Care:

  • Remove makeup completely before bedtime.
  • Avoid harsh soaps, cleansers, shampoos, hair removal products, strong chemicals, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

[RETINOIDS]

All Substitutes & Brand Comparisons

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Alcohol

Caution

The interaction of Deriva MS Aqueous Gel with alcohol is unknown. Please consult a doctor before consuming alcohol while using Deriva MS Aqueous Gel.

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Pregnancy

Caution

Deriva MS Aqueous Gel is a category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Deriva MS Aqueous Gel is excreted in human milk. Therefore, Deriva MS Aqueous Gel is recommended for breastfeeding mothers only if the physician determines that the benefits outweigh the risks. However, do not apply Deriva MS Aqueous Gel on the chest area to avoid contact with the baby.

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Driving

Safe if prescribed

Deriva MS Aqueous Gel usually does not affect your ability to drive or operate machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Deriva MS Aqueous Gel in patients with liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Deriva MS Aqueous Gel in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Deriva MS Aqueous Gel is not recommended for children under 12 years of age, as its safety and efficacy have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Consult your doctor

Limited information available for use of Deriva MS Aqueous Gel in elderly patients. Please consult your doctor.

FAQs

Deriva MS Aqueous Gel is used to treat acne, a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil.

Deriva MS Aqueous Gel works by loosening cells on the skin's surface and unblocking pores by reducing the production of sebum. Thereby, decreases pimples, spots, whiteheads and blackheads. Also, adapalene increases the production of new skin cells and supports natural exfoliation (removal of dead skin cells) in the outer layers of the skin.

Deriva MS Aqueous Gel may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen (SPF 30 or more) and wear protective clothing while going out to prevent sunburn.

No, Deriva MS Aqueous Gel is not recommended for patients with eczema (itchy, cracked, swollen, or rough skin) because it may cause severe irritation. Therefore, if you have eczema, inform your physician before using Deriva MS Aqueous Gel.

Yes, Deriva MS Aqueous Gel may cause skin irritation as a side effect. However, if the irritation persists or worsens, discontinue use of Deriva MS Aqueous Gel and consult a physician.

You are advised not to use other acne products containing erythromycin, benzoyl peroxide or clindamycin with Deriva MS Aqueous Gel at the same time, as it may cause excessive irritation or dry skin. Therefore, it is recommended to use Deriva MS Aqueous Gel at night and other products in the morning. However, please consult a doctor before using any other medicines or products with Deriva MS Aqueous Gel.

Yes, Deriva MS Aqueous Gel may cause skin dryness. You can use a moisturiser while using Deriva MS Aqueous Gel to prevent dry skin. However, do not apply Deriva MS Aqueous Gel and the moisturiser simultaneously, as this may reduce the effectiveness of Deriva MS Aqueous Gel. Please consult a doctor before using other products with Deriva MS Aqueous Gel.

Deriva MS Aqueous Gel may cause side effects such as skin irritation, skin redness, a burning sensation, sunburn, peeling, or dry skin. If these side effects persist or worsen, please consult your doctor.

Yes, Deriva MS Aqueous Gel helps reduce scars after acne.

Blackheads are a type of acne. Thus, Deriva MS Aqueous Gel can be used to manage and treat acne. However, it is advisable to use Deriva MS Aqueous Gel only after a doctor's advice. The doctor will prescribe the same after a proper skin diagnosis. Do not self-medicate.

Deriva MS Aqueous Gel is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.

It is advisable to avoid cosmetic procedures while using Deriva MS Aqueous Gel. Cosmetic products with abrasive, peeling, or drying actions may increase irritant effects. Please consult your doctor if you have any concerns regarding this.

Yes, Deriva MS Aqueous Gel may cause a burning sensation as a common side effect. Additionally, during the first 4 weeks of treatment, you may experience dryness, redness, and scaling, which usually improve as you continue to use Deriva MS Aqueous Gel. If the side effects persist or worsen, inform your doctor.

You may start to see improvement after using Deriva MS Aqueous Gel for two weeks, but it may take at least eight weeks to notice consistent benefits.

If necessary, moisturisers may be used; however, products containing glycolic or alpha hydroxy acids should be avoided.

Deriva MS Aqueous Gel should be applied at night before bedtime or should be used as advised by your doctor. Clean the affected area with water and ensure it is dry before applying Deriva MS Aqueous Gel. Apply it as a thin layer over the entire face and any other affected areas by taking a small amount onto your fingertips. It is important to clean your hands after applying Deriva MS Aqueous Gel.

Avoid contact of Deriva MS Aqueous Gel with the lips, eyes, angles of the nose, and inside of the mouth. Do not apply Deriva MS Aqueous Gel on abrasions, cuts, reddened or inflamed skin, and sunburned skin. Wax epilation should be avoided on treated skin, as it may cause skin erosions.

You are advised to limit your time outdoors in the sun, as Deriva MS Aqueous Gel can make your skin sensitive. If you must be in direct sunlight, wear sunscreen, a hat, and clothing that covers the treated areas. You should avoid exposure to extreme weather, such as cold and wind, as this may irritate your skin. Avoid using certain skin products, such as astringents, harsh soaps, and cosmetics with strong skin-drying effects. In addition, products with high alcohol levels should be avoided, as they may further irritate or dry your skin.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - DER0046

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Feb 10, 2026 | 9:19 AM IST

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