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compositionComposition:METHOTREXATE-1%W/W
prescriptionPrescription Medicine
Dermotrex 1% Gel 30 gm

Dermotrex 1% Gel belongs to the class of antimetabolite medications used in the treatment of psoriasis. This medicine contains methotrexate, which works by interfering with the immune system process that causes psoriasis. Common side effects include nausea, vomiting, fatigue, mouth sores, and loss of appetite. Before starting this medicine, inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

METHOTREXATE-1%W/W

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Dermotrex 1% Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis.

Dermotrex 1% Gel contains 'Methotrexate', which works by suppressing the overactive immune system that is responsible for causing psoriasis.

Dermotrex 1% Gel may cause common side effects such as nausea, vomiting, fatigue, mouth sores, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Consult your doctor if you have a weak immune system, low blood cell count, liver or kidney problems. Do not use Dermotrex 1% Gel if you are pregnant or breastfeeding. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of Dermotrex 1% Gel

Dermotrex 1% Gel is used to treat severe forms of psoriasis. The detailed uses of Dermotrex 1% Gel in psoriasis are as follows:

  • Management of plaque psoriasis: Dermotrex 1% Gel helps reduce the thick, red, scaly patches commonly seen in plaque psoriasis by controlling abnormal skin cell growth.
  • Control of symptoms in resistant cases: Dermotrex 1% Gel is prescribed when topical treatments or phototherapy are ineffective in managing moderate to severe psoriasis.
  • Improvement in quality of life: By reducing inflammation and skin lesions, Dermotrex 1% Gel helps relieve itching, scaling, and discomfort, thereby improving daily functioning and well-being.
  • Long-term disease control: Under medical supervision, Dermotrex 1% Gel can help maintain remission and prevent frequent flare-ups in chronic psoriasis.

Key Benefits

  • Dermotrex 1% Gel suppresses the overactive immune system, helping reduce scaling, redness, and thickening of the skin.
  • It controls immune system activity, reduces inflammation, itching, and flare-ups.
  • It provides long-term control of autoimmune and inflammatory conditions by regulating abnormal immune responses.
Side effects of Dermotrex 1% Gel 30 gm
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Apply Dermotrex 1% Gel as a thin layer on the clean and dry affected area.
  • Wash your hands before and after using Dermotrex 1% Gel to prevent the spread of infection.
Dermotrex 1% Gel contains 'Methotrexate', which works by suppressing the overactive immune system that is responsible for causing psoriasis.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Dermotrex 1% Gel.

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Pregnancy

Unsafe

Dermotrex 1% Gel may cause serious birth defects. It is not recommended to use Dermotrex 1% Gel while you are pregnant.

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Breast Feeding

Unsafe

Dermotrex 1% Gel passes into breast milk. Avoid breastfeeding whilst on treatment with Dermotrex 1% Gel.

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Driving

Caution

It is not known if Dermotrex 1% Gel affects your ability to drive. Drive only if you are alert after using Dermotrex 1% Gel.

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Liver

Caution

Limited information is available. Please consult your doctor if you have liver impairment before using Dermotrex 1% Gel.

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Kidney

Caution

Limited information is available. Please consult your doctor if you have kidney impairment before using Dermotrex 1% Gel.

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Children

Caution

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Dermotrex 1% Gel in children.

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Heart

Caution

Dermotrex 1% Gel is generally safe for individuals with heart problems because it acts locally on the skin with minimal systemic absorption. However, it's important to use it under medical supervision to avoid allergic reactions or interactions with other medications.

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Geriatrics

Caution

Dermotrex 1% Gel can be used in geriatric patients, but with caution due to increased sensitivity to side effects. Regular monitoring and dose adjustments may be needed to ensure safe and effective use.

Use Dermotrex 1% Gel in the prescribed dosage only. An overdose of Dermotrex 1% Gel may cause symptoms like a burning sensation of the skin, pruritus, urticaria, ecchymosis and reversible alopecia, sloughing over pressure points, acute ulcerations of psoriatic plaques, severe mucositis, and reactivation of phototoxic responses. Seek emergency medical help if you face any of these symptoms.

Diet & Lifestyle Advise

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Have a query?

Drug Warnings

  • Do not use Dermotrex 1% Gel if you are allergic to any of the contents.
  • Avoid using Dermotrex 1% Gel if you are pregnant or breastfeeding.
  • Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver or kidney problems.
  • Let your doctor know if you have ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs.
  • Keep your doctor informed if you are taking any other medicines.

Drug-Drug Interactions

verifiedApollotooltip
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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METHOTREXATE-1%W/WCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-1%W/WCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of Dermotrex 1% Gel 30 gm. Avoid taking caffeine while taking Dermotrex 1% Gel 30 gm. This can increase the risk or severity of side effects.

All Substitutes & Brand Comparisons

No
[ANTIMETABOLITES, IMMUNOSUPPRESSANTS]

FAQs

Dermotrex 1% Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis. Psoriasis is a skin disorder in which skin cells multiply faster than usual.

Dermotrex 1% Gel works by suppressing the overactive immune system that is responsible for causing psoriasis. Dermotrex 1% Gel interferes with the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.

Do not cover the treated skin with dressings after applying Dermotrex 1% Gel unless told by the doctor. Covering the skin can increase the amount of medicine absorbed through the skin, leading to harmful effects.

Continue using Dermotrex 1% Gel for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while using Dermotrex 1% Gel.

Protect your skin from sunlight as it will help prevent sunburns and psoriasis flares. Avoid using tanning beds or sunlamps.

Do not apply Dermotrex 1% Gel on wounds, cuts, or damaged skin unless advised by the doctor.

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Author Details

Santoshini Reddy GDoctor badge

Written By

  • Santoshini Reddy G

    M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

  • Veda Maddala

    M Pharmacy

Last Updated

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India
6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - DER0518

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