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  1. Home
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  3. Dermotrex 1% Gel 30 gm

Dermotrex 1% Gel 30 gm, Pack of 1 Gel
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Composition :

METHOTREXATE-1%W/W

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Dermotrex 1% Gel

Dermotrex 1% Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis.

Dermotrex 1% Gel contains 'Methotrexate', which works by suppressing the overactive immune system that is responsible for causing psoriasis.

Dermotrex 1% Gel may cause common side effects such as nausea, vomiting, fatigue, mouth sores, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Consult your doctor if you have a weak immune system, low blood cell count, liver or kidney problems. Do not use Dermotrex 1% Gel if you are pregnant or breastfeeding. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of Dermotrex 1% Gel

Dermotrex 1% Gel is used to treat severe forms of psoriasis. The detailed uses of Dermotrex 1% Gel in psoriasis are as follows:

  • Management of plaque psoriasis: Dermotrex 1% Gel helps reduce the thick, red, scaly patches commonly seen in plaque psoriasis by controlling abnormal skin cell growth.
  • Control of symptoms in resistant cases: Dermotrex 1% Gel is prescribed when topical treatments or phototherapy are ineffective in managing moderate to severe psoriasis.
  • Improvement in quality of life: By reducing inflammation and skin lesions, Dermotrex 1% Gel helps relieve itching, scaling, and discomfort, thereby improving daily functioning and well-being.
  • Long-term disease control: Under medical supervision, Dermotrex 1% Gel can help maintain remission and prevent frequent flare-ups in chronic psoriasis.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Apply Dermotrex 1% Gel as a thin layer on the clean and dry affected area.
  • Wash your hands before and after using Dermotrex 1% Gel to prevent the spread of infection.

Medicinal Benefits

  • Dermotrex 1% Gel suppresses the overactive immune system, helping reduce scaling, redness, and thickening of the skin.
  • It controls immune system activity, reduces inflammation, itching, and flare-ups.
  • It provides long-term control of autoimmune and inflammatory conditions by regulating abnormal immune responses.

How Dermotrex 1% Gel Works

Dermotrex 1% Gel contains 'Methotrexate', which works by suppressing the overactive immune system that is responsible for causing psoriasis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dermotrex 1% Gel out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dermotrex 1% Gel

Use Dermotrex 1% Gel in the prescribed dosage only. An overdose of Dermotrex 1% Gel may cause symptoms like a burning sensation of the skin, pruritus, urticaria, ecchymosis and reversible alopecia, sloughing over pressure points, acute ulcerations of psoriatic plaques, severe mucositis, and reactivation of phototoxic responses. Seek emergency medical help if you face any of these symptoms.

Drug Warnings

  • Do not use Dermotrex 1% Gel if you are allergic to any of the contents.
  • Avoid using Dermotrex 1% Gel if you are pregnant or breastfeeding.
  • Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver or kidney problems.
  • Let your doctor know if you have ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs.
  • Keep your doctor informed if you are taking any other medicines.

Diet & Lifestyle Advise

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Habit Forming

No

Therapeutic Class

ANTIMETABOLITES

Dermotrex 1% Gel Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Dermotrex 1% Gel.

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Pregnancy

Unsafe

Dermotrex 1% Gel may cause serious birth defects. It is not recommended to use Dermotrex 1% Gel while you are pregnant.

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Breast Feeding

Unsafe

Dermotrex 1% Gel passes into breast milk. Avoid breastfeeding whilst on treatment with Dermotrex 1% Gel.

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Driving

Caution

It is not known if Dermotrex 1% Gel affects your ability to drive. Drive only if you are alert after using Dermotrex 1% Gel.

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Liver

Caution

Limited information is available. Please consult your doctor if you have liver impairment before using Dermotrex 1% Gel.

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Kidney

Caution

Limited information is available. Please consult your doctor if you have kidney impairment before using Dermotrex 1% Gel.

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Children

Caution

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Dermotrex 1% Gel in children.

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Heart

Dermotrex 1% Gel is generally safe for individuals with heart problems because it acts locally on the skin with minimal systemic absorption. However, it's important to use it under medical supervision to avoid allergic reactions or interactions with other medications.

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Geriatrics

Caution

Dermotrex 1% Gel can be used in geriatric patients, but with caution due to increased sensitivity to side effects. Regular monitoring and dose adjustments may be needed to ensure safe and effective use.

FAQs

Dermotrex 1% Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis. Psoriasis is a skin disorder in which skin cells multiply faster than usual.

Dermotrex 1% Gel works by suppressing the overactive immune system that is responsible for causing psoriasis. Dermotrex 1% Gel interferes with the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.

Do not cover the treated skin with dressings after applying Dermotrex 1% Gel unless told by the doctor. Covering the skin can increase the amount of medicine absorbed through the skin, leading to harmful effects.

Continue using Dermotrex 1% Gel for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while using Dermotrex 1% Gel.

Protect your skin from sunlight as it will help prevent sunburns and psoriasis flares. Avoid using tanning beds or sunlamps.

Do not apply Dermotrex 1% Gel on wounds, cuts, or damaged skin unless advised by the doctor.

Country of origin

India

Manufacturer/Marketer address

6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - DER0518

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

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Written By

Santoshini Reddy G

M Pharmacy

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Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Oct 14, 2025 | 1:08 PM IST

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Reference

  1. https://www.aad.org/public/diseases/psoriasis/treatment/medications/methotrexate
  2. https://dermnetnz.org/topics/methotrexate

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