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  3. Develex-250 Tablet 10's

Develex-250 Tablet 10's, Pack of 10 TABLETS
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Develex-250 Tablet 10's is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Composition :

DIVALPROEX SODIUM-250MG

Manufacturer/Marketer :

De Merilion Formulation Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Develex-250 Tablet 10's

Develex-250 Tablet 10's belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

The name Develex-250 Tablet 10's contains 'Divalproex sodium,' which works by increasing the levels of a natural brain chemical called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Develex-250 Tablet 10's helps control seizures.

Take Develex-250 Tablet 10's with or without food. You are advised to take Develex-250 Tablet 10's as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Do not stop taking Develex-250 Tablet 10's without consulting your doctor, as this may worsen seizures. Avoid taking Develex-250 Tablet 10's if you are pregnant, as it may cause severe birth defects. Consult your doctor before using Develex-250 Tablet 10's if you are breastfeeding. Develex-250 Tablet 10's should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Develex-250 Tablet 10's may cause drowsiness and dizziness. Avoid consuming alcohol along with Develex-250 Tablet 10's, as it could lead to increased dizziness.

Uses of Develex-250 Tablet 10's

Develex-250 Tablet 10's is used in the treatment of epilepsy (seizures). The detailed uses of Develex-250 Tablet 10's are as follows:<br/>• It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.<br/>• It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).<br/>

Directions for Use

  • Develex-250 Tablet 10's can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

Medicinal Benefits

Develex-250 Tablet 10's belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits). It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures. Develex-250 Tablet 10's is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.

How Develex-250 Tablet 10's Works

Develex-250 Tablet 10's contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Develex-250 Tablet 10's helps control seizures.

Storage

• Store in a cool and dry place away from sunlight.• Keep Develex-250 Tablet 10's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Develex-250 Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Develex-250 Tablet 10's

Do not take more than the prescribed dose of Develex-250 Tablet 10's, as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Develex-250 Tablet 10's if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Inform your doctor before taking Develex-250 Tablet 10's if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Develex-250 Tablet 10's. Develex-250 Tablet 10's may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking Develex-250 Tablet 10's without consulting your doctor to avoid worsening of seizures. Do not take Develex-250 Tablet 10's if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Develex-250 Tablet 10's. Consult your doctor before taking Develex-250 Tablet 10's if you are breastfeeding. Develex-250 Tablet 10's should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as Develex-250 Tablet 10's may cause drowsiness and dizziness. Avoid consuming alcohol along with Develex-250 Tablet 10's, as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateTeriflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Develex-250 Tablet:
Combining Sodium phenylbutyrate and Develex-250 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Develex-250 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Teriflunomide and Develex-250 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Develex-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Ketamine and Develex-250 Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Develex-250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Vorinostat with Develex-250 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Develex-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Leflunomide and Develex-250 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Develex-250 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Lithium with Develex-250 Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Develex-250 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Meropenam and Develex-250 Tablet together can reduce the effect of Develex-250 Tablet.

How to manage the interaction:
Co-administration of Meropenam and Develex-250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Develex-250 Tablet:
Using buprenorphine together with Develex-250 Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Develex-250 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Develex-250 Tablet:
Co-administration of Develex-250 Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Develex-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Develex-250 Tablet:
The combined use of Ertapenem and Develex-250 Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Develex-250 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Develex-250 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Develex-250 Tablet 10's, as it may cause increased drowsiness and dizziness.

bannner image

Pregnancy

Unsafe

Develex-250 Tablet 10's belongs to pregnancy category D. Avoid taking Develex-250 Tablet 10's if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

bannner image

Breast Feeding

Caution

Develex-250 Tablet 10's may pass into breastmilk. Consult your doctor before taking Develex-250 Tablet 10's if you are breastfeeding.

bannner image

Driving

Unsafe

Develex-250 Tablet 10's causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

bannner image

Liver

Unsafe

Develex-250 Tablet 10's should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Develex-250 Tablet 10's should be given to children only if prescribed by a doctor.

Have a query?

FAQs

Develex-250 Tablet 10's belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

Develex-250 Tablet 10's contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Develex-250 Tablet 10's helps control seizures.

Do not discontinue Develex-250 Tablet 10's without consulting your doctor. To treat your condition effectively, continue taking Develex-250 Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Develex-250 Tablet 10's, your doctor will reduce the dose gradually to avoid worsening of seizures.

Develex-250 Tablet 10's may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Develex-250 Tablet 10's. Avoid getting pregnant while taking Develex-250 Tablet 10's as it could lead to severe birth defects. Do not stop taking Develex-250 Tablet 10's and consult your doctor immediately if you become pregnant.

Develex-250 Tablet 10's may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Develex-250 Tablet 10's.

Topiramate (an anticonvulsant) should not be taken along with Develex-250 Tablet 10's as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing Develex-250 Tablet 10's. Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Develex-250 Tablet 10's can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, Develex-250 Tablet 10's can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Develex-250 Tablet 10's, it's essential to consult with your doctor.

Yes, Develex-250 Tablet 10's can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Develex-250 Tablet 10's, seeking medical attention is crucial.

Avoid consumption of alcohol while taking Develex-250 Tablet 10's, as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Develex-250 Tablet 10's, it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Develex-250 Tablet 10's can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Develex-250 Tablet 10's, please seek immediate medical attention.

The common side effects of Develex-250 Tablet 10's include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

88, Jangalpur Rd, Manikpur, Rajbari, Dum Dum, North Dumdum, West Bengal 700081
Other Info - DEV0123

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Reference

  1. https://www.intaspharma.com/wp-content/uploads/2018/12/DIVAA.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018081s056lbl.pdf
  3. https://www.drugs.com/pro/valproic-acid-oral-solution.html
  4. https://medlineplus.gov/druginfo/meds/a682412.html

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