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  3. Dexmedine Injection 0.5ml

Dexmedine Injection 0.5ml, Pack of 1 Injection
Dexmedine Injection 0.5ml, Pack of 1 Injection
Dexmedine Injection 0.5ml, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dexmedine Injection belongs to the class of sedative and hypnotic medicines used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. This medicine works by inhibiting the release of norepinephrine and subsequently blocks pain signals. Common side effects include slow heart rate, a change in blood pressure and an alteration in breathing pattern.
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Composition :

DEXMEDETOMIDINE-100MCG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dexmedine Injection

Dexmedine Injection belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.

Dexmedine Injection contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence Dexmedine Injection brings on a sense of relaxation and numbness through massive pain relief. 

Dexmedine Injection will be administered by a healthcare professional. Do not self-administer. Dexmedine Injection may cause certain common side effects such as a slow heart rate, a change in blood pressure and an alteration in breathing pattern. You are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of Dexmedine Injection . Consult your doctor if you are pregnant, planning to get pregnant or if you are breastfeeding, as Dexmedine Injection should be used with caution in these states. Avoid driving or operating machinery as Dexmedine Injection causes sedation. Consult your doctor before consuming alcohol with Dexmedine Injection .

Uses of Dexmedine Injection

Used for Sedation

Directions for Use

Dexmedine Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Dexmedine Injection is a sedative that is used for the purpose of sedation in acute settings such as the intensive care unit (ICU). Dexmedine Injection finds application in aiding anaesthesia before surgical procedures and is also used to relax patients on mechanical ventilation. Dexmedine Injection contains Dexmedetomidine. Dexmedine Injection blocks pain signals, so the brain doesn't perceive pain or sensation and hence, brings on a sense of numbness and anaesthesia.

How Dexmedine Injection Works

Dexmedine Injection contains Dexmedetomidine which works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals. Hence Dexmedine Injection brings on a sense of relaxation and numbness through massive pain relief.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dexmedine Injection 0.5ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Dexmedine Injection

Since Dexmedine Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Dexmedine Injection . Keep your doctor informed if you suffer from any bleeding disorders, disorders of heart rhythm, hypotension (very low blood pressure), stroke, cardiovascular disorders, neurological problems or liver disease. Consult your doctor before taking alcohol with Dexmedine Injection . Inform the doctor if you are on anticoagulant (blood-thinner) therapy, sedatives, anaesthetics or any pain killers. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding as Dexmedine Injection should be used with caution in these states.

Drug-Drug Interactions

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DexmedetomidineTizanidine
Severe

Drug-Drug Interactions

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DexmedetomidineTizanidine
Severe
How does the drug interact with Dexmedine Injection 0.5ml:
Combining Tizanidine and Dexmedine Injection 0.5ml can increase the risk of low blood pressure.

How to manage the interaction:
Taking Tizanidine and Dexmedine Injection 0.5ml together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, palpitations, chest pain, or excessive sweating, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. 
  • Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
  • Try meditation and deep breathing to reduce overall stress and pain. 
  • Stop smoking as smoking is known to worsen pain conditions. 
  • Engage in mild physical exercise daily and keep your body active. 

Habit Forming

No

Therapeutic Class

SEDATIVES AND HYPNOTICS

Dexmedine Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

There can be a reaction of alcohol with Dexmedine Injection . Use of Dexmedine Injection with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Dexmedine Injection should be used with caution during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Dexmedine Injection should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Dexmedine Injection is used only in hospitalised patients. Avoid driving or operating machinery as Dexmedine Injection causes sedation.

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Liver

Caution

Exercise caution before using Dexmedine Injection in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Dexmedine Injection in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

Dexmedine Injection is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Have a query?

FAQs

Dexmedine Injection belongs to the group of sedatives used to sedate patients in acute settings such as the ICU, during surgical procedures and in those who require a mechanical ventilator. Sedation is defined as a state of relaxation, drowsiness or sleep.

Dexmedine Injection works by inhibiting the release of an active neurotransmitter (nerve substance) called norepinephrine and subsequently blocks pain signals.

Inform your doctor if you have high blood pressure or if you are taking blood pressure-lowering medicines as Dexmedine Injection may cause alterations in blood pressure.

Dexmedine Injection is not recommended for people with heart rhythm problems, and very low blood pressure that does not respond to treatment. Inform your doctor if you have heart problems, abnormally slow heart rate, or high/low blood pressure.

Dexmedine Injection may cause a slow heart rate. Inform your doctor if you have an abnormally slow heart rate as Dexmedine Injection may increase the risk of cardiac arrest.

No, Dexmedine Injection is not a controlled substance. It is a sedative for patients in acute settings such as the ICU, during surgical procedures, and in those who require a mechanical ventilator.

Yes, Dexmedine Injection is approved by the FDA in the year 1999.

In rare cases, Dexmedine Injection may cause amnesia in some individuals as it has sedative and hypnotic properties, leading to memory impairment.

The common side effects of Dexmedine Injection , which may occur in some individuals, include a slow heart rate, blood pressure changes, and breathing patterns. If these side effects persist, you are advised to consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DEX0332

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:46 PM IST

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Reference

  1. https://www.researchgate.net/publication/298788377_Dexmedetomidine_Mechanism_of_Action_an_update
  2. https://www.medicines.org.uk/emc/files/pil.4783.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021038s021lbl.pdf
  4. https://www.ema.europa.eu/en/documents/product-information/dexdor-epar-product-information_en.pdf
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291306/
  6. https://www.sciencedirect.com/topics/neuroscience/dexmedetomidine
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