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compositionComposition:DIVALPROEX SODIUM-250MG
prescriptionPrescription Medicine
DICORATE SOLUTION 100ML
DICORATE SOLUTION 100ML
DICORATE SOLUTION 100ML

DICORATE SOLUTION 1 is used to treat epilepsy, seizures or fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. It helps block the nerve transmission across the brain and provides a calming effect. Thereby, helps treat bipolar disorder. In some cases, it may cause common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DIVALPROEX SODIUM-250MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About DICORATE SOLUTION 1

DICORATE SOLUTION 1 is used to treat epilepsy, seizures or fits. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

DICORATE SOLUTION 1 contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures.

In some cases, you may experience certain common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor about your health, allergies, and medicines to avoid side effects. Do not take DICORATE SOLUTION 1 if you are pregnant, as it could cause severe birth defects. Consult your doctor before taking DICORATE SOLUTION 1 if you are breastfeeding. Use DICORATE SOLUTION 1 cautiously in children under 2 years, due to higher liver risk in the first 6 months.

Uses of DICORATE SOLUTION 1

DICORATE SOLUTION 1 is used in the treatment of seizures, bipolar disorder, and migraine. The detailed uses of DICORATE SOLUTION 1 are as follows:

  • Bipolar Disorder: DICORATE SOLUTION 1 treats manic episodes associated with bipolar disorder, stabilizes mood, and reduces symptoms.
  • Seizure Treatment: DICORATE SOLUTION 1 is used for treating complex partial seizures, absence seizures, and multiple seizure types by stabilizing electrical activity in the brain.
  • Migraine Prevention: DICORATE SOLUTION 1 prevents migraine headaches by reducing frequency and severity.

Have a query?

Directions for Use

  • DICORATE SOLUTION 1 can be taken with or without food, or as advised by the doctor.
  • It is usually taken once daily; however, your doctor may adjust the dose and frequency based on your medical condition.
  • Swallow DICORATE SOLUTION 1 as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Key Benefits

  • DICORATE SOLUTION 1 belongs to a group of medicines called anticonvulsants or anti-epileptics.
  • DICORATE SOLUTION 1 is used to treat epilepsy/seizures/fits. Additionally, DICORATE SOLUTION 1 is also used to treat mood disorders and to prevent migraine headaches.
  • DICORATE SOLUTION 1 decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.
  • DICORATE SOLUTION 1 treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect.
  • DICORATE SOLUTION 1 prevents migraine headaches by limiting the transmission of nerve pain.
  • DICORATE SOLUTION 1 is used alone or in combination to treat simple seizures, complex partial seizures, and complex absence seizures.
  • DICORATE SOLUTION 1 is used in combination to treat multiple seizures, such as absence seizures.

How DICORATE SOLUTION 1 Works

DICORATE SOLUTION 1 contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping in controlling seizures. DICORATE SOLUTION 1 increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dicorate Solution 100ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Avoid tobacco products, as smoking can worsen gum problems.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Consult your dentist if gums bleed consistently.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of DICORATE SOLUTION 1

Please do not take more than the prescribed dose of DICORATE SOLUTION 1, as it may lead to serious side effects. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take DICORATE SOLUTION 1 if you are allergic to any of its contents, have/had liver problems, or urea cycle disorders.
  • Inform your doctor before taking DICORATE SOLUTION 1 if you have pancreatitis, blood problems, or multi-organ hypersensitivity.
  • Consult your doctor immediately if you experience suicidal tendencies while taking DICORATE SOLUTION 1.
  • DICORATE SOLUTION 1 may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems.
  • Please do not stop taking DICORATE SOLUTION 1 without consulting your doctor to avoid worsening of seizures.
  • Do not take DICORATE SOLUTION 1 if you are pregnant, as it could cause serious birth defects.
  • If you are of child-bearing age, use effective contraception while taking DICORATE SOLUTION 1.
  • Avoid driving or operating machinery, as DICORATE SOLUTION 1 can cause dizziness and may affect thinking and motor skills.
  • Avoid consuming alcohol along with DICORATE SOLUTION 1 as it could lead to increased dizziness.
  • Care should be taken while giving DICORATE SOLUTION 1 to children below 2 years, as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateBuprenorphine
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Dicorate Solution 100ml:
Combining Sodium phenylbutyrate and Dicorate Solution 100ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Dicorate Solution 100ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Dicorate Solution 100ml:
Using buprenorphine together with Dicorate Solution 100ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Dicorate Solution 100ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Dicorate Solution 100ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Dicorate Solution 100ml:
The combined use of Ertapenem and Dicorate Solution 100ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Leflunomide and Dicorate Solution 100ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Dicorate Solution 100ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Lithium with Dicorate Solution 100ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Dicorate Solution 100ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Ketamine and Dicorate Solution 100ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Dicorate Solution 100ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Vorinostat with Dicorate Solution 100ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Meropenam and Dicorate Solution 100ml together can reduce the effect of Dicorate Solution 100ml.

How to manage the interaction:
Co-administration of Meropenam and Dicorate Solution 100ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Teriflunomide and Dicorate Solution 100ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

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Alcohol

Unsafe

Avoid consumption of alcohol while taking DICORATE SOLUTION 1, as it may cause increased dizziness.

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Pregnancy

Unsafe

DICORATE SOLUTION 1 belongs to pregnancy category D. Avoid taking DICORATE SOLUTION 1 if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Consult your doctor

DICORATE SOLUTION 1 may pass into breastmilk. Consult your doctor before taking DICORATE SOLUTION 1 if you are breastfeeding.

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Driving

Unsafe

DICORATE SOLUTION 1 causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

DICORATE SOLUTION 1 should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

DICORATE SOLUTION 1 can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below 2 years as they are at a higher risk of liver toxicity.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Caution

DICORATE SOLUTION 1 can be given in elderly patients with extreme caution due to the serious adverse effects.

FAQs

DICORATE SOLUTION 1 belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, DICORATE SOLUTION 1 is also used to treat manic episodes associated with bipolar disorder and to prevent migraine.

DICORATE SOLUTION 1 contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. DICORATE SOLUTION 1 increases the amount of a chemical substance called GABA, which helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.

DICORATE SOLUTION 1 helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, which helps in blocking the nerve transmission across the brain and provides a calming effect.

DICORATE SOLUTION 1 limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Do not discontinue DICORATE SOLUTION 1 without consulting your doctor. To treat your condition effectively, continue taking DICORATE SOLUTION 1 for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking DICORATE SOLUTION 1. Your doctor will reduce the dose gradually to avoid worsening of seizures.

DICORATE SOLUTION 1 may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with DICORATE SOLUTION 1. Avoid getting pregnant while taking DICORATE SOLUTION 1 as it could lead to serious birth defects. Do not stop taking DICORATE SOLUTION 1 and consult your doctor immediately if you become pregnant.

DICORATE SOLUTION 1 may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking DICORATE SOLUTION 1.

Topiramate (anticonvulsant) should not be taken along with DICORATE SOLUTION 1 as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

It is crucial to consult with your doctor before discontinuing DICORATE SOLUTION 1. Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

DICORATE SOLUTION 1 is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.

DICORATE SOLUTION 1 can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, DICORATE SOLUTION 1 can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking DICORATE SOLUTION 1, it's essential to consult with your doctor.

Yes, DICORATE SOLUTION 1 can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking DICORATE SOLUTION 1, seeking medical attention is crucial.

Avoid consumption of alcohol while taking DICORATE SOLUTION 1, as it may cause increased dizziness.

If you experience abdominal pain, nausea, and anorexia while taking DICORATE SOLUTION 1, it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of DICORATE SOLUTION 1 can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of DICORATE SOLUTION 1, please seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - DIC0490

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