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  1. Home
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  3. DICORATE SOLUTION 100ML

DICORATE SOLUTION 100ML , Pack of 1 Liquid
DICORATE SOLUTION 100ML , Pack of 1 Liquid
DICORATE SOLUTION 100ML , Pack of 1 Liquid
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Composition :

DIVALPROEX SODIUM-250MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DICORATE SOLUTION 1

DICORATE SOLUTION 1 belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

The name DICORATE SOLUTION 1 contains 'Divalproex sodium,' which works by increasing the levels of a natural brain chemical called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, DICORATE SOLUTION 1 helps control seizures.

Take DICORATE SOLUTION 1 with or without food. You are advised to take DICORATE SOLUTION 1 as prescribed by your doctor, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Do not stop taking DICORATE SOLUTION 1 without consulting your doctor, as this may worsen seizures. Avoid taking DICORATE SOLUTION 1 if you are pregnant, as it may cause severe birth defects. Consult your doctor before using DICORATE SOLUTION 1 if you are breastfeeding. DICORATE SOLUTION 1 should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as DICORATE SOLUTION 1 may cause drowsiness and dizziness. Avoid consuming alcohol along with DICORATE SOLUTION 1, as it could lead to increased dizziness.

Uses of DICORATE SOLUTION 1

DICORATE SOLUTION 1 is used in the treatment of epilepsy (seizures). The detailed uses of DICORATE SOLUTION 1 are as follows:<br/>• It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.<br/>• It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).<br/>

Directions for Use

  • DICORATE SOLUTION 1 can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

Medicinal Benefits

DICORATE SOLUTION 1 belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits). It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures. DICORATE SOLUTION 1 is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.

How DICORATE SOLUTION 1 Works

DICORATE SOLUTION 1 contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, DICORATE SOLUTION 1 helps control seizures.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dicorate Solution 100ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Avoid tobacco products, as smoking can worsen gum problems.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Consult your dentist if gums bleed consistently.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of DICORATE SOLUTION 1

Do not take more than the prescribed dose of DICORATE SOLUTION 1, as it may lead to an overdose. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose or notice any of these symptoms, please consult a doctor immediately.

Drug Warnings

Do not take DICORATE SOLUTION 1 if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders. Inform your doctor before taking DICORATE SOLUTION 1 if you have pancreatitis, blood problems, or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking DICORATE SOLUTION 1. DICORATE SOLUTION 1 may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems. Please do not stop taking DICORATE SOLUTION 1 without consulting your doctor to avoid worsening of seizures. Do not take DICORATE SOLUTION 1 if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking DICORATE SOLUTION 1. Consult your doctor before taking DICORATE SOLUTION 1 if you are breastfeeding. DICORATE SOLUTION 1 should be given to children only if prescribed by your doctor. Avoid driving or operating machinery, as DICORATE SOLUTION 1 may cause drowsiness and dizziness. Avoid consuming alcohol along with DICORATE SOLUTION 1, as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateErtapenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Dicorate Solution 100ml:
Combining Sodium phenylbutyrate and Dicorate Solution 100ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Dicorate Solution 100ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Dicorate Solution 100ml:
The combined use of Ertapenem and Dicorate Solution 100ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Ketamine and Dicorate Solution 100ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Dicorate Solution 100ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Teriflunomide and Dicorate Solution 100ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Dicorate Solution 100ml:
Using buprenorphine together with Dicorate Solution 100ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Dicorate Solution 100ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Vorinostat with Dicorate Solution 100ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Dicorate Solution 100ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Dicorate Solution 100ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Leflunomide and Dicorate Solution 100ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Dicorate Solution 100ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Lithium with Dicorate Solution 100ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Dicorate Solution 100ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Dicorate Solution 100ml:
Co-administration of Meropenam and Dicorate Solution 100ml together can reduce the effect of Dicorate Solution 100ml.

How to manage the interaction:
Co-administration of Meropenam and Dicorate Solution 100ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking DICORATE SOLUTION 1, as it may cause increased drowsiness and dizziness.

bannner image

Pregnancy

Unsafe

DICORATE SOLUTION 1 belongs to pregnancy category D. Avoid taking DICORATE SOLUTION 1 if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

DICORATE SOLUTION 1 may pass into breastmilk. Consult your doctor before taking DICORATE SOLUTION 1 if you are breastfeeding.

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Driving

Unsafe

DICORATE SOLUTION 1 causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

bannner image

Liver

Unsafe

DICORATE SOLUTION 1 should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

DICORATE SOLUTION 1 should be given to children only if prescribed by a doctor.

Have a query?

FAQs

DICORATE SOLUTION 1 belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

DICORATE SOLUTION 1 contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, DICORATE SOLUTION 1 helps control seizures.

Do not discontinue DICORATE SOLUTION 1 without consulting your doctor. To treat your condition effectively, continue taking DICORATE SOLUTION 1 for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking DICORATE SOLUTION 1, your doctor will reduce the dose gradually to avoid worsening of seizures.

DICORATE SOLUTION 1 may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with DICORATE SOLUTION 1. Avoid getting pregnant while taking DICORATE SOLUTION 1 as it could lead to severe birth defects. Do not stop taking DICORATE SOLUTION 1 and consult your doctor immediately if you become pregnant.

DICORATE SOLUTION 1 may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking DICORATE SOLUTION 1.

Topiramate (an anticonvulsant) should not be taken along with DICORATE SOLUTION 1 as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing DICORATE SOLUTION 1. Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

DICORATE SOLUTION 1 can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, DICORATE SOLUTION 1 can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking DICORATE SOLUTION 1, it's essential to consult with your doctor.

Yes, DICORATE SOLUTION 1 can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking DICORATE SOLUTION 1, seeking medical attention is crucial.

Avoid consumption of alcohol while taking DICORATE SOLUTION 1, as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking DICORATE SOLUTION 1, it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of DICORATE SOLUTION 1 can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of DICORATE SOLUTION 1, please seek immediate medical attention.

The common side effects of DICORATE SOLUTION 1 include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - DIC0490

Disclaimer

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Reference

  1. https://www.intaspharma.com/wp-content/uploads/2018/12/DIVAA.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018081s056lbl.pdf
  3. https://www.drugs.com/pro/valproic-acid-oral-solution.html
  4. https://medlineplus.gov/druginfo/meds/a682412.html

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