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compositionComposition:DIENOGEST-2MG
prescriptionPrescription Medicine
Dinofirst Tablet 15's
Dinofirst Tablet 15's

Dinofirst Tablet is used to treat endometriosis. It contains Dienogest, which suppresses the production of a hormone (oestradiol) that causes excess growth in the endometrium. In some cases, this medicine may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DIENOGEST-2MG

Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dinofirst Tablet

Dinofirst Tablet is used for the management of painful symptoms of endometriosis. Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.

Dinofirst Tablet contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Dinofirst Tablet helps in treating pelvic pain associated with endometriosis.

In some cases, Dinofirst Tablet may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Do not take Dinofirst Tablet if you are allergic to any of its components. Avoid taking Dinofirst Tablet if you are pregnant, planning for pregnancy or breastfeeding. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Dinofirst Tablet

Dinofirst Tablet is used in the management of endometriosis. The detailed uses of Dinofirst Tablet are as follows:

  • Manages Endometriosis: Dinofirst Tablet helps relieve pelvic pain and inflammation associated with endometriosis by suppressing the production of estradiol (a hormone) and preventing the abnormal growth of endometrial tissue outside the uterus.
  • Manages Heavy Menstrual Bleeding: It may help control and reduce prolonged or heavy menstrual bleeding (menorrhagia) associated with endometriosis.
  • Support in Menopausal Hormonal Therapy: It may be used as part of hormone replacement therapy during menopause (the permanent end of periods) to balance hormone levels and relieve menopausal symptoms such as hot flashes and vaginal dryness.

Key Benefits

  • Dinofirst Tablet is primarily indicated for the management of endometriosis, a condition where tissue similar to the lining of the uterus (endometrium) grows outside the uterus, causing pain and other symptoms.
  • It works by suppressing the production of estradiol, a hormone that promotes the abnormal growth of endometrial tissue.
  • By reducing estradiol levels, Dinofirst Tablet helps shrink endometrial tissue and relieve pain and discomfort associated with endometriosis.
  • It regulates hormone levels and may also help reduce excessive menstrual bleeding, making it useful in the treatment of heavy periods.
  • Dinofirst Tablet can be used as part of hormone replacement therapy (HRT) in menopausal women to balance estrogen levels, reducing the risk of endometrial thickening and providing symptom relief.
  • It provides effective hormonal control to manage endometriosis, reduce pelvic pain, regulate heavy bleeding, and support hormone balance during menopause.
Side effects of Dinofirst Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
  • Eat fiber-rich foods, fruits, and vegetables.
  • Monitor calorie intake and limit external food sources.
  • Weigh yourself weekly to track progress.
  • Enjoy balanced meals and indulge in treats moderately.
  • Prioritize sleep, exercise, and stress-reducing techniques.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.

Directions for Use

  • Dinofirst Tablet can be taken with or without food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Dinofirst Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Dinofirst Tablet Works

Dinofirst Tablet contains Dienogest, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Dinofirst Tablet helps in treating pelvic pain associated with endometriosis.
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Alcohol

Caution

It is unknown if Dinofirst Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Dinofirst Tablet is not recommended during pregnancy. Please consult your doctor if you have any concerns regarding this. Consult your doctor immediately if you become pregnant while taking Dinofirst Tablet .

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Breast Feeding

Unsafe

Avoid taking Dinofirst Tablet if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

Dinofirst Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be necessary. Dinofirst Tablet should not be taken by people with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Dinofirst Tablet should not be given to children who have not had their first period.

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Heart

Caution

Dinofirst Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Dinofirst Tablet .

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Geriatrics

Unsafe

Dinofirst Tablet is not intended for use or prescribing in elderly patients.

What if I have taken an overdose of Dinofirst Tablet

An overdose of Dinofirst Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Include diet-fibrous foods, iron-rich foods, foods rich in essential fatty acids, and antioxidant-rich foods.
  • Maintain a healthy diet and exercise regularly.
  • Practice meditation and yoga. Acupuncture and massages can also be helpful.
  • Avoid or limit caffeine intake.

Health Queries

What is the difference between danazol and dinofirst, and how are they used in endometriosis?

Vikas Singh

Vikas Singh

M Pharmacy

Danazol and Dinofirst are both used to manage Endometriosis, but they work differently and have different side effect profiles. Endometriosis happens when tissue similar to the uterine lining grows outside the uterus and causes pelvic pain, painful periods, bloating, or fertility-related problems. Danazol works by suppressing hormones that stimulate endometriosis tissue growth, but it may cause side effects such as weight gain, acne, oily skin, hair growth, voice changes, or mood changes because it has androgen-like effects. Dinofirst contains dienogest, a progesterone-related medicine that helps reduce endometriosis activity and pain with a more targeted hormonal effect. It is often preferred now because it is generally better tolerated for long-term use in many women. Both medicines should be taken only under a gynaecologist's supervision because treatment choice depends on age, pain severity, fertility plans, bleeding pattern, and medical history. Regular follow-up is important to monitor symptom control and side effects.

Have a query?

How Soon It Starts Working

The time required for Dinofirst Tablet to start to work: Dinofirst Tablet ideally shows its action within 1.5 to 2 hours after administration.

The time for which the effects of Dinofirst Tablet last: The effect of Dinofirst Tablet lasts for 24 hours.

What if you forget to take Dinofirst Tablet

If you miss a dose of Dinofirst Tablet , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dinofirst Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Dinofirst Tablet if you are allergic to any of its components.
  • Dinofirst Tablet is not recommended if you have a blood clot in the lungs, heart, brain, blood vessels of legs or any part of the body, if you have/had diabetes mellitus with damaged blood vessels, severe liver damage, unexplained vaginal bleeding, or a benign or malignant tumour.
  • Talk to your doctor if you have diabetes, high blood pressure, depression, are overweight, have chloasma (yellowish-brown pigmentation on the skin), had an ectopic pregnancy (embryo develops outside the womb), or if you or anyone in your immediate family has had blood clots in lungs/legs, or heart attack, high cholesterol or stroke.
  • Avoid taking Dinofirst Tablet if you are pregnant, planning for pregnancy or breastfeeding.
  • Consult your doctor immediately if you become pregnant while taking Dinofirst Tablet .
  • Dinofirst Tablet should not be given to children who have not had their first period.
  • Dinofirst Tablet may cause dizziness, so drive with caution.
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions: Dinofirst Tablet may interact with anti-epileptics (phenytoin, primidone, carbamazepine, oxcarbazepine, topiramate, felbamate, phenobarbitone), anti-depressants (fluoxetine, fluvoxamine), anti-hypertensives (diltiazem, verapamil), anti-TB (rifampicin, rifabutin), anti-fungal (ketoconazole, itraconazole, fluconazole, voriconazole), antibiotics (erythromycin, clarithromycin), antacids (cimetidine), and herbal supplements used to treat depression (St. John’s wort).

Drug-Food Interactions: Avoid consumption of grapefruit while taking Dinofirst Tablet . 

Drug-Disease Interactions: Inform your doctor if you have diabetes mellitus with damaged blood vessels, severe liver damage, unexplained vaginal bleeding, or a benign or malignant tumour.

DienogestEfavirenz
Critical
DienogestCarbamazepine
Severe

Drug-Drug Interactions

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DienogestEfavirenz
Critical
How does the drug interact with Dinofirst Tablet:
When Efavirenz is taken with Dinofirst Tablet, it can lower the metabolism of Dinofirst Tablet and increase the risk or severity of side effects.

How to manage the interaction:
Taking Efavirenz with Dinofirst Tablet can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
DienogestCarbamazepine
Severe
How does the drug interact with Dinofirst Tablet:
Taking carbamazepine with Dinofirst Tablet may increase the effect of carbamazepine.

How to manage the interaction:
Although there is a possible interaction, Dinofirst Tablet can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
DienogestFosphenytoin
Severe
How does the drug interact with Dinofirst Tablet:
When Dinofirst Tablet is taken with Fosphenytoin, it can increase the risk of severe bleeding.

How to manage the interaction:
Although taking Dinofirst Tablet and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DienogestDantrolene
Severe
How does the drug interact with Dinofirst Tablet:
Co-administration of Dantrolene with Dinofirst Tablet can cause serious side effects that may affect your liver.

How to manage the interaction:
Taking Dinofirst Tablet with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
DienogestBosentan
Severe
How does the drug interact with Dinofirst Tablet:
Co-administration of Dinofirst Tablet with Bosentan may decrease the effectiveness of Dinofirst Tablet.

How to manage the interaction:
Although there is a possible interaction, Dinofirst Tablet can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DienogestPrimidone
Severe
How does the drug interact with Dinofirst Tablet:
Taking Dinofirst Tablet with Primidone may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between primidone and Dinofirst Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DienogestMycophenolic acid
Severe
How does the drug interact with Dinofirst Tablet:
Co-administration of Dinofirst Tablet with Mycophenolic acid may decrease the levels and action of Dinofirst Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Dinofirst Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
DienogestPhenytoin
Severe
How does the drug interact with Dinofirst Tablet:
Taking Phenytoin with Dinofirst Tablet may reduce the blood levels and effects of Dinofirst Tablet.

How to manage the interaction:
Although taking Phenytoin and Dinofirst Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Dinofirst Tablet as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dinofirst Tablet with Grapefruit and Grapefruit juice may increase the side effects of Dinofirst Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Dinofirst Tablet.

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FAQs

Dinofirst Tablet is indicated for the management of painful symptoms of endometriosis, a condition in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.

Dinofirst Tablet suppresses the production of a hormone called estradiol, which causes excess growth of the endometrium. Thereby, Dinofirst Tablet helps in treating pelvic pain associated with endometriosis.

Dinofirst Tablet may cause weight gain. Maintain a healthy weight by exercising regularly. Try eating smaller but more frequent meals. Consult your doctor if you notice severe weight gain.

Do not stop taking Dinofirst Tablet on your own. Continue taking Dinofirst Tablet for as long as your doctor has prescribed it for you, depending on your condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Dinofirst Tablet .

Avoid using hormonal contraceptives with Dinofirst Tablet ; instead, use non-hormonal contraceptive methods such as condoms or barrier methods. Please consult your doctor; he/she may advise regarding proper contraception.

Antibiotics and antifungal medicines might affect how Dinofirst Tablet works or might be affected by Dinofirst Tablet . Therefore, consult your doctor before taking antibiotics or antifungals with Dinofirst Tablet .

Dinofirst Tablet may cause irregular menstrual bleeding or infrequent periods. Talk to your doctor if you experience this.

Long-term use of Dinofirst Tablet might lower bone mineral density and affect bone health. An adequate intake of calcium and vitamin D, either via your food or supplements, may be helpful.

Dinofirst Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.

Dinofirst Tablet should be swallowed as a whole with water; do not crush or chew it.

Dinofirst Tablet contains dienogest, which belongs to a group of medicines called progestin and is indicated for the management of endometriosis.

Yes, Dinofirst Tablet is a synthetic steroid.

Dinofirst Tablet helps endometriosis by suppressing the production of a hormone called estradiol, which causes excess growth in the endometrium.

Dinofirst Tablet may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Talk to your doctor if any of the side effects persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

204, 2Nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India.
Other Info - DIN0105

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