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  1. Home
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  3. Diocid-O Tablet 10's

Prescription drug
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Diocid-O Tablet 10's, Pack of 10
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Diocid-O Tablet contains Omeprazole and Ondansetron, which are used in the treatment of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment, or surgery. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron works by blocking the action of serotonin, a chemical that stimulates the vomiting centre located in the brain. Thus, it prevents nausea and vomiting.

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Composition :

OMEPRAZOLE-10MG + ONDANSETRON-4MG

Manufacturer/Marketer :

Intra Labs India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Diocid-O Tablet

Diocid-O Tablet is used in the treatment of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is forcible voluntary or involuntary emptying of stomach contents through the mouth.

Diocid-O Tablet is a combination of two drugs, namely Omeprazole (proton pump inhibitor) and Ondansetron (anti-emetic). Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

Take Diocid-O Tablet as prescribed. Your doctor will advise you on how often you should take it based on your medical condition. Diocid-O Tablet may cause common side effects such as headache, a feeling of warmth, constipation, diarrhoea, or flatulence (wind). Most of these side effects of Diocid-O Tablet do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor. 

If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Diocid-O Tablet . If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Diocid-O Tablet .

Uses of Diocid-O Tablet

Diocid-O Tablet is used in the treatment of Nausea and Vomiting. The detailed uses of Diocid-O Tablet are as follows:

  • Nausea and vomiting: Diocid-O Tablet is used in the treatment of nausea and vomiting, especially after chemotherapy, radiation therapy, or surgery.
  • Gastroesophageal reflux disease (GERD): Diocid-O Tablet is used in the treatment of Gastroesophageal reflux disease.
  • Treatment of ulcers: Diocid-O Tablet is used in the treatment of peptic ulcers and acid-related disorders with associated nausea.

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Directions for Use

  • Diocid-O Tablet should be taken one hour before a meal.
  • It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
  • Swallow Diocid-O Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Diocid-O Tablet belongs to a group of medicines called gastrointestinal agents that prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. It contains Omeprazole and Ondansetron. Omeprazole works by blocking the action of proton pumps that produce stomach acid. It reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

How Diocid-O Tablet Works

Diocid-O Tablet contains Omeprazole and Ondansetron. Omeprazole works by blocking the action of proton pumps that produce stomach acid. It reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight. • Keep it out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Diocid-O Tablet

Do not exceed the recommended dose. An overdose of Diocid-O Tablet can be harmful. It may cause symptoms such as Sudden blindness (2-3 minutes duration), severe constipation, diarrhoea, feeling or being sick (nausea or vomiting), feeling dizzy, stomach pain, headache, lack of interest, feeling depressed and confusion. If you encounter these symptoms or think you might have taken too much, get medical help immediately.

Drug Warnings

If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Diocid-O Tablet . If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Diocid-O Tablet . If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Diocid-O Tablet .  Omeprazole in Diocid-O Tablet may alter the results of some tests related to cancer. Therefore, tell your doctor, nurse or hospital staff you are taking Diocid-O Tablet . Your doctor may advise you to stop taking this medicine for at least five days if you undergo certain tests.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Diocid-O Tablet:
Taking Diocid-O Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Diocid-O Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OmeprazoleRilpivirine
Critical
How does the drug interact with Diocid-O Tablet:
Using rilpivirine together with Diocid-O Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Diocid-O Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazoleErlotinib
Critical
How does the drug interact with Diocid-O Tablet:
Diocid-O Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Diocid-O Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OndansetronVandetanib
Severe
How does the drug interact with Diocid-O Tablet:
Taking Diocid-O Tablet with vandetanib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Diocid-O Tablet along with vandetanib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronAmitriptyline
Severe
How does the drug interact with Diocid-O Tablet:
Coadministration of Amitriptyline and Diocid-O Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although combining Amitriptyline with Diocid-O Tablet can lead to an interaction, they can be taken if prescribed by a doctor. If you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, get emergency medical help. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medication without consulting a doctor.
OndansetronDuloxetine
Severe
How does the drug interact with Diocid-O Tablet:
Taking Diocid-O Tablet with duloxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Although taking Diocid-O Tablet with duloxetine can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
OndansetronIloperidone
Severe
How does the drug interact with Diocid-O Tablet:
Taking Diocid-O Tablet with Iloperidone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Diocid-O Tablet along with Iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronCeritinib
Severe
How does the drug interact with Diocid-O Tablet:
Taking ceritinib together with Diocid-O Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Diocid-O Tablet along with ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronSumatriptan
Severe
How does the drug interact with Diocid-O Tablet:
Using Diocid-O Tablet together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Diocid-O Tablet along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronFurazolidone
Severe
How does the drug interact with Diocid-O Tablet:
When Diocid-O Tablet, is taken with furazolidone it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Diocid-O Tablet along with furazolidone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy, low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

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Alcohol

Consult your doctor

If you have any concerns regarding alcohol consumption while taking Diocid-O Tablet , please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, please inform your doctor before taking Diocid-O Tablet .

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Breast Feeding

Consult your doctor

If you are a breastfeeding mother, please inform your doctor before taking Diocid-O Tablet .

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Driving

Caution

Diocid-O Tablet usually does not affect your ability to drive or operate machinery. However, if you experience visual disturbances or dizziness after taking Diocid-O Tablet , avoid driving or operating machinery.

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Liver

Caution

If you have severe liver problems, inform your doctor, as a lower dose is recommended in such cases.

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Kidney

Consult your doctor

If you have kidney problems, please inform your doctor before taking Diocid-O Tablet .

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Children

Caution

Diocid-O Tablet should be used in dose and duration as advised by a doctor only. However, if you have any concerns regarding using Diocid-O Tablet for children below 1 year, please consult a doctor.

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Heart

Diocid-O Tablet should be used cautiously in heart patients due to the risk of rhythm changes like QT prolongation. Always consult a doctor to ensure safe use based on your cardiac condition.

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Geriatrics

Caution

Diocid-O Tablet can be used in geriatric patients, but with caution due to age-related changes in drug metabolism. Older adults may be more prone to side effects like constipation, dizziness, or nutrient deficiencies, so medical supervision is recommended.

FAQs

Diocid-O Tablet is used to treat Nausea and Vomiting.

Diocid-O Tablet contains Omeprazole and Ondansetron. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Diocid-O Tablet may cause constipation as a side effect. It is not necessary for everyone taking Diocid-O Tablet to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

Diocid-O Tablet should be used with caution in patients suffering from liver problems. Inform your doctor if you have any liver problems before taking Diocid-O Tablet so that the dose may be adjusted appropriately.

Country of origin

India

Manufacturer/Marketer address

#1/13, Arunodaya, 7th cross, New Guddadahalli, Mysore Road, Bangalore - 560026.
Other Info - DIO0109

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 10, 2025 | 3:34 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5222.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf
  3. https://www.hpra.ie/img/uploaded/swedocuments/Leaflet-2191137-11072017125746-636353746685625000.pdf

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