Doran-O Tablet 10's
MRP ₹97
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About Doran-O Tablet
Doran-O Tablet is used in the treatment of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is forcible voluntary or involuntary emptying of stomach contents through the mouth.
Doran-O Tablet is a combination of two drugs, namely Omeprazole (proton pump inhibitor) and Ondansetron (anti-emetic). Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Take Doran-O Tablet as prescribed. Your doctor will advise you on how often you should take it based on your medical condition. Doran-O Tablet may cause common side effects such as headache, a feeling of warmth, constipation, diarrhoea, or flatulence (wind). Most of these side effects of Doran-O Tablet do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Doran-O Tablet . If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Doran-O Tablet .
Uses of Doran-O Tablet
Doran-O Tablet is used in the treatment of Nausea and Vomiting. The detailed uses of Doran-O Tablet are as follows:
- Nausea and vomiting: Doran-O Tablet is used in the treatment of nausea and vomiting, especially after chemotherapy, radiation therapy, or surgery.
- Gastroesophageal reflux disease (GERD): Doran-O Tablet is used in the treatment of Gastroesophageal reflux disease.
- Treatment of ulcers: Doran-O Tablet is used in the treatment of peptic ulcers and acid-related disorders with associated nausea.
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Directions for Use
- Doran-O Tablet should be taken one hour before a meal.
- It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
- Swallow Doran-O Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
Doran-O Tablet belongs to a group of medicines called gastrointestinal agents that prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. It contains Omeprazole and Ondansetron. Omeprazole works by blocking the action of proton pumps that produce stomach acid. It reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
How Doran-O Tablet Works
Storage
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Drug Warnings
If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Doran-O Tablet . If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Doran-O Tablet . If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Doran-O Tablet . Omeprazole in Doran-O Tablet may alter the results of some tests related to cancer. Therefore, tell your doctor, nurse or hospital staff you are taking Doran-O Tablet . Your doctor may advise you to stop taking this medicine for at least five days if you undergo certain tests.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Doran-O Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.
How to manage the interaction:
Taking Doran-O Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Using rilpivirine together with Doran-O Tablet can decrease the absorption and blood levels of rilpivirine.
How to manage the interaction:
Taking Doran-O Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Doran-O Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.
How to manage the interaction:
Taking Doran-O Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Doran-O Tablet with mifepristone can increase the risk of irregular heart rhythms.
How to manage the interaction:
Taking Doran-O Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Coadministration of Doran-O Tablet with Trazodone may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).
How to manage the interaction:
Although taking Doran-O Tablet along with trazodone can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
When Doran-O Tablet, is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).
How to manage the interaction:
Although taking Doran-O Tablet along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
Taking Doran-O Tablet with hydroxychloroquine increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Doran-O Tablet along with hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
When Doran-O Tablet is taken with doxepin, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).
How to manage the interaction:
Although taking Doran-O Tablet along with doxepin can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
Using Doran-O Tablet together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.
How to manage the interaction:
Co-administration of Doran-O Tablet along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
Taking Doran-O Tablet with nilotinib increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Doran-O Tablet along with nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat a healthy, low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
- Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
- Drink any other liquid at least 30 minutes after eating food.
- If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
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Alcohol
Safe if prescribed
If you have any concerns regarding alcohol consumption while taking Doran-O Tablet , please discuss them with your doctor.
Pregnancy
Consult your doctor
If you are pregnant or planning pregnancy, please inform your doctor before taking Doran-O Tablet .
Breast Feeding
Consult your doctor
If you are a breastfeeding mother, please inform your doctor before taking Doran-O Tablet .
Driving
Safe if prescribed
Doran-O Tablet usually does not affect your ability to drive or operate machinery. However, if you experience visual disturbances or dizziness after taking Doran-O Tablet , avoid driving or operating machinery.
Liver
Consult your doctor
If you have severe liver problems, inform your doctor, as a lower dose is recommended in such cases.
Kidney
Consult your doctor
If you have kidney problems, please inform your doctor before taking Doran-O Tablet .
Children
Safe if prescribed
Doran-O Tablet should be used in dose and duration as advised by a doctor only. However, if you have any concerns regarding using Doran-O Tablet for children below 1 year, please consult a doctor.
Heart
Doran-O Tablet should be used cautiously in heart patients due to the risk of rhythm changes like QT prolongation. Always consult a doctor to ensure safe use based on your cardiac condition.
Geriatrics
Consult your doctor
Doran-O Tablet can be used in geriatric patients, but with caution due to age-related changes in drug metabolism. Older adults may be more prone to side effects like constipation, dizziness, or nutrient deficiencies, so medical supervision is recommended.
FAQs
Doran-O Tablet is used to treat Nausea and Vomiting.
Doran-O Tablet contains Omeprazole and Ondansetron. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Doran-O Tablet may cause constipation as a side effect. It is not necessary for everyone taking Doran-O Tablet to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Doran-O Tablet should be used with caution in patients suffering from liver problems. Inform your doctor if you have any liver problems before taking Doran-O Tablet so that the dose may be adjusted appropriately.
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