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compositionComposition:PRAZIQUANTEL-600MG
prescription
Prescription Medicine
info
Distoside Tablet 4's
Distoside Tablet 4's
Distoside Tablet is used to treat parasitic infections such as Schistosoma and liver fluke. It contains Praziquantel which works by paralysing the worms. This causes the worms to release their hold on the blood vessels so they can be removed from the body. In some cases, this medicine may cause side effects such as headache, dizziness, abdominal discomfort, nausea, and fever.
Read more
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PRAZIQUANTEL-600MG

Manufacturer/Marketer :

Chandra Bhagat Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Distoside Tablet

Distoside Tablet belongs to the class of medicines called anthelmintics used to treat infections due to Schistosoma and liver fluke. Schistosomiasis, also known as snail fever, Katayama fever, and bilharzia, is a disease caused by infection with freshwater parasitic flatworms called schistosomes. Liver fluke infection is caused by parasitic worms called liver flukes after eating contaminated raw or uncooked watercress or freshwater fish.
 
Distoside Tablet contains ‘Praziquantel’, which kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels. It also stops the parasite from absorbing sugars. The parasite then disintegrates with the help of white blood cells and passes out of the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections.
 
You are advised to take Distoside Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience side effects such as headache, dizziness, abdominal discomfort, nausea, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid driving or operating machinery on the day of treatment and the following day, as Distoside Tablet may cause dizziness. Consult your doctor if you are pregnant, planning for pregnancy, or think you are pregnant. Avoid breastfeeding whilst taking Distoside Tablet and during the subsequent 72 hours/3 days. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Distoside Tablet

Distoside Tablet used in the treatment of Schistosomiasis and liver fluke infection. The detailed uses of Distoside Tablet are as follows:

  • Schistosomiasis Treatment: Distoside Tablet treats schistosomiasis caused by all species of Schistosoma, such as Schistosoma mekongi, Schistosoma japonicum, Schistosoma mansoni, and Schistosoma hematobium, by targeting and eliminating the parasites.
  • Liver Fluke Infections Treatment: Distoside Tablet effectively treats liver fluke infections caused by Clonorchis sinensis (clonorchiasis) and Opisthorchis viverrini (opisthorchiasis), helping to alleviate symptoms and promote recovery.

Key Benefits

Distoside Tablet belongs to the class of medicines called anthelmintics used to treat infections due to Schistosoma and liver fluke. Distoside Tablet kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels so they can be removed from the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections. Distoside Tablet may also be used to treat other worm infections, including tapeworm infection.

Side effects of Distoside Tablet
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.

Directions for Use

  • Distoside Tablet can be taken with meals to enhance absorption and maximize its effectiveness.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Distoside Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Distoside Tablet Works

Distoside Tablet contains ‘Praziquantel’, which kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels. It also stops the parasite from absorbing sugars. The parasite then disintegrates with the help of white blood cells and passes out of the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections.
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Alcohol

Caution

Avoid alcohol consumption as it might cause increased dizziness.

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Pregnancy

Caution

Distoside Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if clearly needed.

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Breast Feeding

Unsafe

Distoside Tablet may pass into breastmilk. Avoid breastfeeding whilst taking Distoside Tablet and during the subsequent 72 hours/3 days.

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Driving

Unsafe

Distoside Tablet may cause dizziness. Avoid driving or operating machinery on the day of treatment and the following day.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Distoside Tablet in patients with liver impairment. Distoside Tablet should be used with caution in patients with moderate to severe liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Distoside Tablet in patients with kidney impairment.

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Children

Caution

Safety of Distoside Tablet in children below 4years has not been established.

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Heart

Caution

Distoside Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Distoside Tablet.

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Geriatrics

Caution

Distoside Tablet should be given with caution in elderly patients due to an increased risk of side effects. Talk to your doctor if you have any concerns.

What if I have taken an overdose of Distoside Tablet

Take Distoside Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Always eat thoroughly cooked fish and meat.
  • Avoid consuming contaminated food and water.
  • Include iron-rich foods, such as leafy vegetables, legumes, and fortified foods.
  • Avoid raw or uncooked meat.
  • Drink boiled and purified water.
  • Avoid consuming foods kept in open markets as they might be contaminated.
  • Wash or reheat food that has been around for a long time.
  • Always wash fruits and vegetables thoroughly with fresh water before consumption.

Health Queries

My child has been diagnosed with multiple neurocysticercosis (NCC) cysts. What medication or treatment is recommended for this condition?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

I understand this diagnosis can be concerning, but multiple neurocysticercosis is highly treatable. The standard treatment typically involves a combination of two antiparasitic medications, albendazole and praziquantel, which work together to clear the cysts. Before starting these, your doctor will prescribe a corticosteroid (like prednisolone) to prevent inflammation and swelling in the brain as the parasites clear. If your child has had any seizures, an antiseizure medication will also be prescribed. Please consult a pediatric neurologist or infectious disease specialist to safely tailor the correct dosage based on your child's weight. With proper medical care, most children recover completely.

Have a query?

How Soon It Starts Working

The time required for Distoside Tablet to start to work: The time required for Distoside Tablet to show its action is unknown. The time for which the effects of Distoside Tablet last: Distoside Tablet effect lasts for 6 hours.

What if you forget to take Distoside Tablet

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Distoside Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Distoside Tablet if you are allergic to any of its components, if you are taking rifampicin (a medicine used to treat tuberculosis), dexamethasone (corticosteroid), and antiepileptic medicines. Avoid taking Distoside Tablet if you have parasitic eye infections. Inform your doctor if you have heart problems, epilepsy, skin nodules, kidney or liver problems. Consult your doctor if you are pregnant, planning for pregnancy, or think you are pregnant. Avoid breastfeeding whilst taking Distoside Tablet and during the subsequent 72 hours/3 days. Safety of Distoside Tablet in children below 4 years has not been established; consult a doctor if you have any concerns. Avoid driving or operating machinery on the day of treatment and the following day, as Distoside Tablet may cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Distoside Tablet may interact with antibiotic (rifampicin, erythromycin), corticosteroid (dexamethasone), antacid (cimetidine), antimalarial (chloroquine), antifungal (ketoconazole, itraconazole), and antiepileptic medicines.

Drug-Food Interactions: Grapefruit may interact with Distoside Tablet leading to unwanted side effects. Therefore, avoid consumption of grapefruit or grapefruit juice while taking Distoside Tablet.

Drug-Disease Interactions: Inform your doctor if you have parasitic eye infections, seizures, arrhythmia, or liver impairment.

PraziquantelPhenytoin
Critical
PraziquantelCarbamazepine
Critical

Drug-Drug Interactions

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PraziquantelPhenytoin
Critical
How does the drug interact with Distoside Tablet:
Using Distoside Tablet together with phenytoin may significantly reduce the blood levels of Distoside Tablet leading decreased effectiveness.

How to manage the interaction:
Taking Phenytoin with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PraziquantelCarbamazepine
Critical
How does the drug interact with Distoside Tablet:
When Distoside Tablet is taken with Carbamazepine, it may decrease the blood levels of Distoside Tablet, which may make Distoside Tablet less effective in treating your condition.

How to manage the interaction:
Taking Carbamazepine with Distoside Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
PraziquantelPhenobarbital
Critical
How does the drug interact with Distoside Tablet:
Using Distoside Tablet together with Phenobarbital may significantly reduce the blood levels of Distoside Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Phenobarbital with Distoside Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PraziquantelPrimidone
Critical
How does the drug interact with Distoside Tablet:
Taking Distoside Tablet with primidone can lower the levels of Distoside Tablet in your blood, which leads to a decreased therapeutic effect.

How to manage the interaction:
Taking Primidone with Distoside Tablet is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PraziquantelFosphenytoin
Severe
How does the drug interact with Distoside Tablet:
When Distoside Tablet is taken with Fosphenytoin, it can cause the body to break down Distoside Tablet faster. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Fosphenytoin and Distoside Tablet, but it can be taken if prescribed by a doctor. If you experience symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PraziquantelDexamethasone
Severe
How does the drug interact with Distoside Tablet:
Taking Dexamethasone may reduce the blood levels of Distoside Tablet, making the medication less effective.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Distoside Tablet if prescribed by the doctor. Consult a doctor if your symptoms worsen or your condition changes. Do not discontinue the medication without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHELMINTICS]

FAQs

Distoside Tablet is used to treat parasitic infections, including Schistosomiasis and liver fluke infection.
Distoside Tablet kills the parasites by paralysing the worms. This causes the worms to release their hold on the blood vessels so that they can be removed from the body. Thereby, Distoside Tablet helps treat schistosomiasis and liver fluke infections.
To treat your infection effectually, continue taking Distoside Tablet for as long as it has been prescribed by the doctor. Do not be reluctant to speak with the doctor if you experience any difficulty while taking Distoside Tablet.
Concomitant administration of Distoside Tablet with rifampin is not recommended as therapeutically effective blood levels of Distoside Tablet may not be achieved when taken together. Consult your doctor if you are taking rifampin; your doctor may prescribe alternate medicine. However, if treatment with Distoside Tablet is necessary, rifampin should be discontinued 4 weeks before starting Distoside Tablet. Rifampin can be restarted one day after the completion of treatment with Distoside Tablet.
Distoside Tablet is unlikely to cause diarrhoea. Eat non-spicy food and drink plenty of fluids if you experience diarrhoea. If you notice bloody diarrhoea, consult your doctor immediately.
Avoid taking Distoside Tablet if you have parasitic eye infections, as killing the parasite might cause blindness. Talk to your doctor if you have any concerns regarding this.
Yes. Distoside Tablet is effective treatment for Schistosomiasis infections (Infection with the type of worm that lives in the bloodstream) and Liver fluke infections (Infection with a type of worm that lives in or nearer the liver), when it is taken as directed by the physician.
Yes. Distoside Tablet may cause dizziness in some cases. Do not drive a vehicle or do anything that requires mental focus until you feel normal.
Do not take Distoside Tablet if you are allergic to any of its ingredients, have a parasitic eye infection, or are pregnant. Additionally, breastfeeding should be avoided while taking Distoside Tablet and for 3 days after finishing the medication. It's also important to note that Distoside Tablet has not been proven safe for children under 4 years old, so be sure to consult a doctor before giving it to your child.
Store Distoside Tablet in its original container, tightly closed. Follow the storage instructions on the label. Dispose of any unused medicine safely. Keep out of reach of children, pets, and others to avoid accidental consumption.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Distoside Tablet is safe when used correctly, but like all medicines, it can have some side effects. To ensure safe use, it's important to talk to a healthcare professional before taking it. They will provide guidance and instructions on how to use Distoside Tablet effectively. By following their advice, you can minimize the risk of side effects and use the medication safely.
The common side effects of Distoside Tablet may include headache, dizziness, abdominal discomfort, nausea, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 018714S012Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Praziquantel Pregnancy and Lactation Reference Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026] Check here
  4. MedlinePlus. A608048 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  5. Praziquantel Praziquantel. 2014. [Accessed on 31 Mar. 2019] Check here
  6. Praziquantel. NIH National Library of Medicine. National Center for Biotechnology Information. August 2022. [Accessed on 6th August 2022] Check here
  7. Macleods Pharmaceuticals Limited. Praziquantel. [Revised in April 2020] [Accessed on 6th August 2022] 0.pdfCheck here

Country of origin

INDIA

Manufacturer/Marketer address

501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071
Other Info - DIS0049

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