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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Divaa-OD 250 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines. It contains Divalproex, which decreases the brain's excessive and abnormal nerve activity. In some cases, it may cause side effects such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DIVALPROEX-250MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Divaa-OD 250 Tablet

Divaa-OD 250 Tablet is used to treat epilepsy/seizures/fits. Additionally, Divaa-OD 250 Tablet is also used to treat manic episodes associated with bipolar disorder and prevent migraines. Epilepsy is a sudden rush of electricity in the brain.

Divaa-OD 250 Tablet contains 'Divalproex', which reduces excessive, abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Divaa-OD 250 Tablet increases the levels of the chemical substance GABA; this helps block nerve transmission in the brain and produces a calming effect. Thereby helping treat bipolar disorder.

In some cases, you may experience side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Talk to your doctor if you experience these side effects persistently.

Do not take Divaa-OD 250 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Divaa-OD 250 Tablet . Consult your doctor if you are breastfeeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Divaa-OD 250 Tablet

Divaa-OD 250 Tablet is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Divaa-OD 250 Tablet are as follows:

  • Seizure Management: Divaa-OD 250 Tablet is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.
  • Bipolar Disorder Treatment: Divaa-OD 250 Tablet can be utilised in the treatment of bipolar disorder, aiding in mood stabilisation and reducing the frequency of mood swings.
  • Migraine Prevention: Divaa-OD 250 Tablet may also be prescribed to prevent migraines, providing relief from recurrent headaches.

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Directions for Use

  • Divaa-OD 250 Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Divaa-OD 250 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Divaa-OD 250 Tablet is used to treat and prevent epilepsy, seizures, or fits by controlling abnormal electrical activity in the brain.
  • It helps manage various types of seizures, including simple partial, complex partial, and absence seizures.
  • Divaa-OD 250 Tablet may be used alone or in combination with other anti-epileptic medicines for better seizure control.
  • It is also prescribed to treat mood disorders, such as bipolar disorder, by enhancing GABA (gamma-aminobutyric acid) activity in the brain, which produces a calming and stabilising effect.
  • Divaa-OD 250 Tablet helps prevent migraine headaches by reducing abnormal nerve transmission and limiting the spread of pain signals.
  • By decreasing excessive nerve activity, Divaa-OD 250 Tablet restores normal brain function and helps maintain emotional balance.
  • Divaa-OD 250 Tablet provides broad neurological benefits by controlling seizures, stabilising mood, and reducing migraine frequency.

How Divaa-OD 250 Tablet Works

Divaa-OD 250 Tablet contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Divaa-OD 250 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Divaa-OD 250 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Write things in a notebook or on sticky notes.
  • Be physically and mentally active.
  • Maintain social interaction to avoid stress and depression which could contribute to memory loss.
  • Sleep well as inadequate sleep may also cause memory loss.
  • Maintain a healthy diet which includes fruits, vegetables, whole grains, fish and skinless poultry.
  • Avoid alcohol consumption as it may cause confusion and memory loss.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Divaa-OD 250 Tablet

Do not take more than the prescribed dose of Divaa-OD 250 Tablet as it may cause overdose resulting in heart block, excess sleepiness and deep coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Divaa-OD 250 Tablet if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders.
  • Inform your doctor before taking Divaa-OD 250 Tablet if you have pancreatitis, blood problems or multi-organ hypersensitivity.
  • Consult your doctor immediately if you experience suicidal tendencies while taking Divaa-OD 250 Tablet .
  • Divaa-OD 250 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems.
  • Please do not stop taking Divaa-OD 250 Tablet without consulting your doctor to avoid worsening of seizures.
  • Do not take Divaa-OD 250 Tablet if you are pregnant, as it could cause serious birth defects.
  • If you are of childbearing age, use effective contraception while taking Divaa-OD 250 Tablet .
  • Consult your doctor before taking Divaa-OD 250 Tablet if you are breastfeeding.
  • Avoid driving or operating machinery as Divaa-OD 250 Tablet causes dizziness and may affect thinking and motor skills.
  • Avoid consuming alcohol along with Divaa-OD 250 Tablet as it could lead to increased dizziness.
  • Care should be taken while giving Divaa-OD 250 Tablet to children below 2 years, as there is a higher risk of liver intoxication during the first six months of treatment.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Divaa-OD 250 Tablet:
Coadministration of Glycerol phenylbutyrate and Divaa-OD 250 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Divaa-OD 250 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Divaa-OD 250 Tablet and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Divaa-OD 250 Tablet and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Divaa-OD 250 Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaa-OD 250 Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
How does the drug interact with Divaa-OD 250 Tablet:
Coadministration of Ketoconazole and Divaa-OD 250 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Divaa-OD 250 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Divaa-OD 250 Tablet and Doripenem can reduce the blood levels of Divaa-OD 250 Tablet sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Divaa-OD 250 Tablet with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Divaa-OD 250 Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Divaa-OD 250 Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexSodium oxybate
Severe
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Sodium oxybate and Divaa-OD 250 Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Divaa-OD 250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexVorinostat
Severe
How does the drug interact with Divaa-OD 250 Tablet:
Coadministration of Divaa-OD 250 Tablet and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Divaa-OD 250 Tablet and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
DivalproexLomitapide
Severe
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Divaa-OD 250 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaa-OD 250 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
How does the drug interact with Divaa-OD 250 Tablet:
Co-administration of Divaa-OD 250 Tablet and Meropenem can reduce the blood levels of Divaa-OD 250 Tablet sodium.

How to manage the interaction:
Co-administration of Divaa-OD 250 Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, help those around you know what to do.
  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Divaa-OD 250 Tablet as it may cause increased dizziness.

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Pregnancy

Unsafe

Divaa-OD 250 Tablet belongs to pregnancy category D. Avoid taking Divaa-OD 250 Tablet if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Divaa-OD 250 Tablet may pass into breastmilk. Consult your doctor before taking Divaa-OD 250 Tablet if you are breastfeeding.

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Driving

Unsafe

Divaa-OD 250 Tablet causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery.

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Liver

Caution

Divaa-OD 250 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Divaa-OD 250 Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below two years, as they are at a higher risk of liver toxicity.

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Heart

Divaa-OD 250 Tablet can be used in cardiac patients, but requires careful monitoring.

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Geriatrics

Caution

Divaa-OD 250 Tablet should be used under caution in geriatric patients for conditions like bipolar mania and seizures. Please consult your physician.

FAQs

Divaa-OD 250 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines.

Divaa-OD 250 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Divaa-OD 250 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, which helps in blocking the nerve transmission across the brain and provides a calming effect.

Divaa-OD 250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Divaa-OD 250 Tablet may interact with aspirin and cause abnormal side-effects. So, it is recommended to take any medication along with Divaa-OD 250 Tablet only after consulting a doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DIV0002

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