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  3. Dobustat 250 mg Injection 1's

Prescription drug
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Dobustat 250 mg Injection 1's, Pack of 1 INJECTION
Dobustat 250 mg Injection 1's, Pack of 1 INJECTION
Dobustat 250 mg Injection 1's, Pack of 1 INJECTION
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Composition :

DOBUTAMINE-250MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dobustat 250 mg Injection

Dobustat 250 mg Injection belongs to a class of medicines called vasopressors used to treat patients with low cardiac output, decompensated heart failure (DHF), and Myocardial infarction (MI). Myocardial infarction, also known as a heart attack, could occur due to the lack of blood and oxygen supply to the heart. Cardiac decompensation is an abnormal condition in which the heart is no longer able to maintain efficient circulation.  

Dobustat 250 mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Dobustat 250 mg Injection will be administered by a healthcare professional. Hence, do not self-administer. Sometimes, Dobustat 250 mg Injection may cause common side effects such as headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Dobutamine or other ingredients of Dobustat 250 mg Injection, please inform your doctor. If you are pregnant or breastfeeding or have a history of blood circulation problems, inform your doctor before receiving Dobustat 250 mg Injection. Dobustat 250 mg Injection is not recommended for children as safety and effectiveness are not established.

Uses of Dobustat 250 mg Injection

Treatment of Myocardial infarction and Decompensated heart failure

Have a query?

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Dobustat 250 mg Injection will be administered by the doctor or healthcare professional in a medical setting.• Do not self-administer.

Medicinal Benefits

Dobustat 250 mg Injection contains Dobutamine which is used to treat Cardiac decompensation and low cardiac output patients. It works by increasing blood flow to the muscles. Additionally, it may be used in people with congestive heart failure (heart failure due to the build-up of blood or fluid) to help the heart pump better by increasing the pumping efficiency of the heart.

How Dobustat 250 mg Injection Works

Dobustat 250 mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Dobustat 250 mg Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dobustat 250 mg Injection
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Limit or avoid intake of stimulants like tobacco, caffeine and alcohol.
  • Drink sufficient water to maintain electrolyte balance.
  • Regularly do aerobic exercises.
  • Practice relaxation techniques such as meditation, or deep breathing to reduce stress.
  • Some medicines may be advised by your doctor such as beta-blockers or calcium channel blockers based on your condition.

What if I have taken an overdose of Dobustat 250 mg Injection

As Dobustat 250 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Dobustat 250 mg Injection may cause anginal and nonspecific chest pain, anorexia, anxiety, headache, hypertension, myocardial ischaemia, nausea, palpitations, shortness of breath, tachyarrhythmias, tremor, ventricular fibrillation, and vomiting.

Drug Warnings

If you are allergic to Dobutamine or any other ingredients of Dobustat 250 mg Injection, please tell your doctor. Dobustat 250 mg Injection is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before receiving Dobustat 250 mg Injection. If you have a history of blood circulation problems, inform your doctor, as you will be monitored for any changes in the colour or temperature of your fingers or toes. If you experience any pain or swelling at the injection site during or immediately after the injection, inform your doctor immediately so that appropriate treatment may be given.

Drug-Drug Interactions

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DobutamineClomipramine
Severe
DobutamineDoxepin
Severe

Drug-Drug Interactions

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DobutamineClomipramine
Severe
How does the drug interact with Dobustat 250 mg Injection:
Taking clomipramine with Dobustat 250 mg Injection can increase the effects of Dobustat 250 mg Injection.

How to manage the interaction:
Although taking Dobustat 250 mg Injection and Clomipramine together can cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your blood pressure regularly. If you notice any unusual symptoms, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DobutamineDoxepin
Severe
How does the drug interact with Dobustat 250 mg Injection:
Doxepin can enhance the blood pressure-raising effects of Dobustat 250 mg Injection.

How to manage the interaction:
There may be a possibility of interaction between Dobustat 250 mg Injection and Doxepin, but it can be taken if prescribed by a doctor. If you experience any symptoms contact your doctor immediately. Do not stop using any medications without a doctor's advice.
DobutamineNortriptyline
Severe
How does the drug interact with Dobustat 250 mg Injection:
Coadministration of Nortriptyline with Dobustat 250 mg Injection can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nortriptyline with Dobustat 250 mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing headaches, tremors, palpitations, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DobutamineAmitriptyline
Severe
How does the drug interact with Dobustat 250 mg Injection:
Coadministration of Amitriptyline with Dobustat 250 mg Injection can enhance the blood pressure-raising effects of Dobustat 250 mg Injection.

How to manage the interaction:
Although there is a possible interaction between Amitriptyline and Dobustat 250 mg Injection, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your blood pressure regularly. If you notice any of these symptoms like Itchy skin or red skin rash, swollen eyes, lips, hands, and feet, feeling lightheaded or dizzy, swelling of the mouth, throat, or tongue, which can cause breathing and swallowing difficulty, coughing, stomach discomfort, nausea, vomiting, or unconsciousness, make sure to consult a doctor. Do not discontinue any medications without consulting a doctor.
DobutamineLinagliptin
Severe
How does the drug interact with Dobustat 250 mg Injection:
Co-administration of Dobustat 250 mg Injection and Linagliptin may interfere with blood glucose control and reduce the effectiveness of linagliptin.

How to manage the interaction:
Co-administration of Linagliptin with Dobustat 250 mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals more frequently.
  • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
  • Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
  • Take frequent breaks if you exercise outdoors in extreme heat.
  • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Habit Forming

No

Therapeutic Class

VASOPRESSORS

Dobustat 250 mg Injection Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid consumption of alcohol. Please discuss with your doctor if you have concerns.

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Pregnancy

Caution

Dobustat 250 mg Injection is considered safe to be used in pregnancy. However, if you are pregnant or planning pregnancy, inform your doctor before receiving Dobustat 250 mg Injection.

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Breast Feeding

Caution

Limited data are available on the effect of Dobustat 250 mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Dobustat 250 mg Injection.

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Driving

Not applicable

Dobustat 250 mg Injection is generally intended for use in hospitalized patients.

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Liver

Caution

If you have liver problems, inform your doctor before receiving Dobustat 250 mg Injection. Your doctor may adjust the dose of this medicine if necessary or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney problems, inform your doctor before receiving Dobustat 250 mg Injection. Your doctor may adjust the dose of this medicine if necessary or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Dobustat 250 mg Injection is not recommended for children as safety and effectiveness were not established in children.

FAQs

Dobustat 250 mg Injection is used to treat Myocardial infarction and Decompensated heart failure.

Dobustat 250 mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Dobustat 250 mg Injection should be used with caution in diabetic patients as it may cause Dobutamine stress echocardiography. Therefore, if you have diabetes, inform your doctor before receiving Dobustat 250 mg Injection.

The common side effects of Dobustat 250 mg Injection include headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Dobustat 250 mg Injection can be used for children if recommended by a doctor or paediatrician. It is generally used for the treatment of low cardiac output and systemic blood pressure in children of all ages. However, the dosage will be determined by the doctor based on the child's weight, age, and specific medical condition.

Dobustat 250 mg Injection is not a steroid. It belongs to a class of medicines called vasopressors and works by increasing blood flow to the muscles and improving the pumping efficiency of the heart. It does not have anti-inflammatory properties like steroids.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DOB0017

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Reference

  1. https://www.drugs.com/mtm/dobutamine.html
  2. https://www.sciencedirect.com/topics/medicine-and-dentistry/dobutamine
  3. https://reference.medscape.com/drug/dobutamine-342434

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