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About DOBUTAMINE

DOBUTAMINE belongs to a class of medicines called vasopressors used to treat patients with low cardiac output, decompensated heart failure (DHF), and Myocardial infarction (MI). Myocardial infarction, also known as a heart attack, could occur due to the lack of blood and oxygen supply to the heart. Cardiac decompensation is an abnormal condition in which the heart is no longer able to maintain efficient circulation.  

DOBUTAMINE contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

DOBUTAMINE will be administered by a healthcare professional. Hence, do not self-administer. Sometimes, DOBUTAMINE may cause common side effects such as headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Dobutamine or other ingredients of DOBUTAMINE, please inform your doctor. If you are pregnant or breastfeeding or have a history of blood circulation problems, inform your doctor before receiving DOBUTAMINEDOBUTAMINE is not recommended for children as safety and effectiveness are not established.

Uses of DOBUTAMINE

Myocardial infarction, Decompensated heart failure.

Medicinal Benefits

DOBUTAMINE contains Dobutamine which is used to treat Cardiac decompensation and low cardiac output patients. It works by increasing blood flow to the muscles. Additionally, it may be used in people with congestive heart failure (heart failure due to the build-up of blood or fluid) to help the heart pump better by increasing the pumping efficiency of the heart.

Directions for Use

DOBUTAMINE will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DOBUTAMINE

  • Headache
  • Nausea
  • Shortness of breath
  • Chest pain
  • Irregular heartbeat
  • Injection site reactions.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Dobutamine or any other ingredients of DOBUTAMINE, please tell your doctor. DOBUTAMINE is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before receiving DOBUTAMINE. If you have a history of blood circulation problems, inform your doctor, as you will be monitored for any changes in the colour or temperature of your fingers or toes. If you experience any pain or swelling at the injection site during or immediately after the injection, inform your doctor immediately so that appropriate treatment may be given.

Drug Interactions

Drug-Drug Interactions: Caution should be maintained if you are taking beta-blockers (propranolol, metoprolol), anticonvulsants (phenytoin), antipsychotics (Amoxapine), anti-depressants (e.g. amitriptyline, clomipramine, imipramine, nortriptyline) inform your doctor before receiving DOBUTAMINE.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Avoid receiving DOBUTAMINE if you have hyperthyroidism (overactive thyroid gland), irregular or rapid heartbeats or a tumour that causes an increase in blood pressure. If you have a history of blood circulation problems or have diabetes, high blood pressure, Raynaud’s disease (fingers become white and very painful when cold), or liver or kidney problems, inform your doctor before receiving DOBUTAMINE.

Drug-Drug Interactions Checker List:

  • NORTRIPTYLINE
  • IMIPRAMINE
  • PHENYTOIN
  • AMITRIPTYLINE
  • PROPRANOLOL
  • AMOXAPINE
  • METOPROLOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol. Please discuss with your doctor if you have concerns.

    • Safety Warning

      Pregnancy

      caution

      DOBUTAMINE is considered safe to be used in pregnancy. However, if you are pregnant or planning pregnancy, inform your doctor before receiving DOBUTAMINE.

    • Safety Warning

      Breast Feeding

      caution

      Limited data are available on the effect of DOBUTAMINE on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving DOBUTAMINE.

    • Safety Warning

      Driving

      not applicable

      DOBUTAMINE is generally intended for use in hospitalized patients.

    • Safety Warning

      Liver

      caution

      If you have liver problems, inform your doctor before receiving DOBUTAMINE. Your doctor may adjust the dose of this medicine if necessary or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Kidney

      caution

      If you have kidney problems, inform your doctor before receiving DOBUTAMINE. Your doctor may adjust the dose of this medicine if necessary or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Children

      unsafe

      DOBUTAMINE is not recommended for children as safety and effectiveness were not established in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat small meals more frequently.
    • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
    • Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
    • Take frequent breaks if you exercise outdoors in extreme heat.
    • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

    Special Advise

     

    Patients Concern

    Disease/Condition Glossary

    Myocardial infarction (MI)/Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form plaque in the arteries that feed the heart (coronary arteries). Heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

    Decompensated heart failure (DHF): It is a condition in which the heart is no longer able to maintain efficient circulation. This leads to the sudden onset of symptoms of heart failure.

    FAQs

    How does DOBUTAMINE work?

    DOBUTAMINE contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

    Is DOBUTAMINE safe for diabetic patients?

    DOBUTAMINE should be used with caution in diabetic patients as it may cause Dobutamine stress echocardiography. Therefore, if you have diabetes, inform your doctor before receiving DOBUTAMINE.

    Available Medicines for

    DOBUTAMINE