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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Doloxicam Injection 5 x 2 ml contains piroxicam, which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is mainly used to relieve pain, swelling, and stiffness caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis (inflammation of the joints). It is sometimes also used to reduce back pain. This medicine inhibits cyclo-oxygenase (COX) enzymes, and this helps reduce pain.

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Composition :

PIROXICAM-20MG

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Doloxicam Injection 5 x 2 ml

Doloxicam Injection 5 x 2 ml is used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage).

Doloxicam Injection 5 x 2 ml contains Piroxicam, which works by blocking the action of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes, which make another chemical, prostaglandins.

In some cases, you may experience certain common side effects such as injection site reactions, diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time.

Consult your doctor before taking Doloxicam Injection 5 x 2 ml if you are pregnant or breastfeeding. Doloxicam Injection 5 x 2 ml is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Doloxicam Injection 5 x 2 ml as it could lead to increased drowsiness and dizziness.

Uses of Doloxicam Injection 5 x 2 ml

Doloxicam Injection 5 x 2 ml is used in the treatment of Musculoskeletal pain, Osteoarthritis, and Rheumatoid arthritis. The detailed uses of Doloxicam Injection 5 x 2 ml are as follows:

  • Rheumatoid Arthritis: Doloxicam Injection 5 x 2 ml is used to reduce inflammation and pain associated with rheumatoid arthritis, helping to slow disease progression.
  • Osteoarthritis: Doloxicam Injection 5 x 2 ml manages osteoarthritis by alleviating joint pain, stiffness, and swelling, improving joint function and mobility.
  • Musculoskeletal Disorders: Doloxicam Injection 5 x 2 ml relieves pain and inflammation in musculoskeletal conditions, such as strains and sprains, improving overall mobility.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Doloxicam Injection 5 x 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Key Benefits

  • Doloxicam Injection 5 x 2 ml belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat musculoskeletal pain.
  • It is also used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain.
  • Doloxicam Injection 5 x 2 ml works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins.
  • Prostaglandins are produced at the injury site and cause pain and swelling.
  • By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Doloxicam Injection 5 x 2 ml Works

Doloxicam Injection 5 x 2 ml contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Doloxicam Injection 5 x 2 ml

A healthcare professional administers Doloxicam Injection 5 x 2 ml as prescribed. Hence, the chances of overdose are less. Overdose may cause a lack of energy, drowsiness, upset stomach, vomiting, stomach pain, bloody, black, or tarry stools, vomiting a substance that is bloody or looks like coffee grounds, and difficulty breathing. Your doctor may initiate the necessary treatment if an overdose is suspected.

Drug Warnings

  • Doloxicam Injection 5 x 2 ml may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Doloxicam Injection 5 x 2 ml.
  • Besides this, Doloxicam Injection 5 x 2 ml may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems.
  • Do not take Doloxicam Injection 5 x 2 ml if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase the risk of a heart attack.
  • Consult your doctor before taking Doloxicam Injection 5 x 2 ml if you are pregnant or breastfeeding.
  • Doloxicam Injection 5 x 2 ml may cause dizziness, so drive only if you are alert.
  • Doloxicam Injection 5 x 2 ml is not recommended for children as safety has not been established.
  • Avoid consuming alcohol along with Doloxicam Injection 5 x 2 ml as it could lead to increased dizziness and may increase the risk of stomach bleeding.
  • Inform your doctor before taking Doloxicam Injection 5 x 2 ml if you have asthma, water retention (oedema) or high blood pressure, a stuffy/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Doloxicam Injection 5 x 2 ml:
Co-administration of Cidofovir with Doloxicam Injection 5 x 2 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Doloxicam Injection 5 x 2 ml with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Using ketorolac tromethamine together with Doloxicam Injection 5 x 2 ml may increase the risk of side effects.

How to manage the interaction:
Taking Doloxicam Injection 5 x 2 ml with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Coadministration of Warfarin with Doloxicam Injection 5 x 2 ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Doloxicam Injection 5 x 2 ml with Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.
PiroxicamDicoumarol
Severe
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Coadministration of Doloxicam Injection 5 x 2 ml with Dicoumarol can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Doloxicam Injection 5 x 2 ml and Dicoumarol, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Coadministration of Doloxicam Injection 5 x 2 ml with Adefovir dipivoxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Doloxicam Injection 5 x 2 ml with Adefovir dipivoxil together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamIbritumomab tiuxetan (90y)
Severe
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Using ibritumomab tiuxetan together with Doloxicam Injection 5 x 2 ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Doloxicam Injection 5 x 2 ml with Ibritumomab tiuxetan (90y) can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Taking Doloxicam Injection 5 x 2 ml with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Fondaparinux and Doloxicam Injection 5 x 2 ml, you can take these medicines together if prescribed by a doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PiroxicamSulindac
Severe
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Using Doloxicam Injection 5 x 2 ml together with sulindac may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Co-administration of Doloxicam Injection 5 x 2 ml with Sulindac can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Coadministration of Doloxicam Injection 5 x 2 ml and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Combination of Doloxicam Injection 5 x 2 ml and Apixaban may cause an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
PiroxicamEdoxaban
Severe
How does the drug interact with Doloxicam Injection 5 x 2 ml:
Coadministration of Doloxicam Injection 5 x 2 ml with Edoxaban can increase the risk of bleeding.

How to manage the interaction:
Taking Doloxicam Injection 5 x 2 ml with Edoxaban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating healthy foods.
  • Get adequate sleep, as rest for the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress by meditating, reading, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

[ANALGESICS]
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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption while taking Doloxicam Injection 5 x 2 ml. Alcohol intake, along with Doloxicam Injection 5 x 2 ml, may cause increased dizziness. It may also increase the risk of stomach/intestine ulcers and bleeding.

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Pregnancy

Consult your doctor

Avoid taking Doloxicam Injection 5 x 2 ml if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Doloxicam Injection 5 x 2 ml only if the benefits outweigh the risks. Do not take Doloxicam Injection 5 x 2 ml in the last 20 weeks of pregnancy as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while taking Doloxicam Injection 5 x 2 ml. Please consult your doctor if you have any concerns.

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Driving

Safe if prescribed

Doloxicam Injection 5 x 2 ml may cause dizziness. Do not drive or operate heavy machinery if you experience dizziness.

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Liver

Consult your doctor

Dose adjustment may be needed. Doloxicam Injection 5 x 2 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Doloxicam Injection 5 x 2 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Doloxicam Injection 5 x 2 ml is not recommended for children, as the efficacy and safety have not been established.

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Heart

Doloxicam Injection 5 x 2 ml should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Doloxicam Injection 5 x 2 ml.

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Geriatrics

Consult your doctor

Doloxicam Injection 5 x 2 ml should be used with caution and may require dose adjustment in elderly patients. Please consult your doctor if you have any concerns.

FAQs

Doloxicam Injection 5 x 2 ml belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders.

Doloxicam Injection 5 x 2 ml works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side-effect of Doloxicam Injection 5 x 2 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not use Doloxicam Injection 5 x 2 ml immediately before or after bypass surgery. Doloxicam Injection 5 x 2 ml may increase the risk of heart attack or stroke. Therefore, inform your doctor if you have heart problems.

Doloxicam Injection 5 x 2 ml may be used to treat musculoskeletal pain. Musculoskeletal pain refers to the pain in the bones, muscles, ligaments, and tendon.

Country of origin

India

Manufacturer/Marketer address

Triton Healthcare Pvt Ltd, Plot No. 75, Natarajan Street, Dhanalakshmi Colony, Vadapalani, Chennai - 600 026.
Other Info - DOL0578

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