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  1. Home
  2. Medicine

  3. Domipen 10 mg Tablet 10's

Prescription drug
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Domipen 10 mg Tablet 10's, Pack of 10 TabletS
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Extra 15% Off with Bank Offers

Composition :

DOMPERIDONE-10MG

Manufacturer/Marketer :

Morepen Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Domipen 10 mg Tablet

Domipen 10 mg Tablet is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps treat indigestion.

Domipen 10 mg Tablet contains domperidone, which prevents nausea and vomiting by blocking certain receptors (such as dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) in the brain. It also acts as a prokinetic agent, increasing the motility of the upper gastrointestinal tract and helping decrease stomach emptying time.

Take Domipen 10 mg Tablet as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Domipen 10 mg Tablet . However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Domipen 10 mg Tablet for longer than seven days. The most common side effect of Domipen 10 mg Tablet is dry mouth. This side effect is temporary and may resolve over time; however, if it persists, contact the doctor.

Do not consume Domipen 10 mg Tablet if you are hypersensitive to any components present in Domipen 10 mg Tablet . Before taking the Domipen 10 mg Tablet , inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Domipen 10 mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be higher in the elderly (those over 60 years old) or in those taking doses higher than 30 mg daily.

Uses of Domipen 10 mg Tablet

Domipen 10 mg Tablet is used to treat nausea and vomiting. The detailed uses of Domipen 10 mg Tablet are as follows:

  • Nausea Relief: Domipen 10 mg Tablet is commonly used to relieve nausea and vomiting caused by various conditions, including motion sickness and post-operative effects.
  • Gastroesophageal Reflux Disease (GERD): Domipen 10 mg Tablet helps manage GERD symptoms by reducing stomach acid and promoting gastric emptying, thereby alleviating discomfort.
  • Functional Dyspepsia: Domipen 10 mg Tablet can help treat functional dyspepsia, providing relief from bloating, early satiety, and stomach discomfort.
  • Gastroparesis: For patients with delayed gastric emptying (gastroparesis), Domipen 10 mg Tablet can help stimulate gastric motility, thereby improving symptoms of indigestion and fullness.

Have a query?

Directions for Use

  • Domipen 10 mg Tablet can be taken with or without food, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Domipen 10 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Domipen 10 mg Tablet relieves nausea and vomiting caused by various conditions or medications.
  • Promotes faster gastric emptying by increasing the movement of the stomach and intestines.
  • Helps reduce fullness, bloating, and post-meal discomfort.
  • Improves digestion and prevents feelings of heaviness or indigestion.
  • Useful in managing symptoms of gastroparesis (delayed stomach emptying).
  • Helps relieve nausea associated with migraine and other treatments.
  • Improves overall digestive comfort and gastrointestinal motility.

How Domipen 10 mg Tablet Works

Domipen 10 mg Tablet contains domperidone, which prevents nausea and vomiting by blocking certain receptors (such as dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) in the brain. It also acts as a prokinetic agent, increasing motility of the upper gastrointestinal tract and helping decrease stomach emptying time.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Domipen 10 mg Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Eat a balanced diet rich in fruits, vegetables, whole grains, and healthy fats.
  • Engage in regular moderate exercise, avoiding excessive strenuous activity.
  • Practice relaxation techniques like deep breathing, meditation, or yoga to manage stress.
  • Ensure adequate sleep and hydration.
  • Track your menstrual cycle to monitor patterns and symptoms.
  • Increase calorie intake and aim for a healthy energy balance.
  • Prioritize healthy fats annd take omega-3 rich foods like fatty fish, avocado, nuts, and seeds.
  • Eat complex carbohydrates like whole grains like brown rice, quinoa, whole wheat bread, and oats.
  • Ensure adequate protein intake like lean protein sources like chicken, fish, beans, lentils, and tofu.
  • Include calcium-rich foods such as dairy products like milk, yogurt, and fortified plant-based options.
  • Consume vitamin D sources like fortified milk, fatty fish, or consider supplementation.
  • Practice relaxation techniques like yoga, meditation, and deep breathing exercises to manage stress.
  • Do moderate exercise and reduce intensity or duration to prevent hormonal disruption.
  • Aim for 7-8 hours of restful sleep each night to help your body and mind recharge.
  • Stay hydrated by drinking plenty of water.
  • Maintain a healthy body weight through balanced diet and exercise.
  • Consult a healthcare professional before making significant dietary changes, especially if suspecting a medical cause for amenorrhea.

What if I have taken an overdose of Domipen 10 mg Tablet

Do not take more than the prescribed dose of Domipen 10 mg Tablet as it may cause an overdose. The symptoms of overdose include uncontrolled movements, which include unusual eye movements, sleepiness, confusion, abnormal posture (such as a twisted neck) or unusual movements of the tongue. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not consume Domipen 10 mg Tablet if you are allergic to any components present in Domipen 10 mg Tablet .
  • Before taking the Domipen 10 mg Tablet , contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure).
  • Prolonged intake of Domipen 10 mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be higher in the elderly (those over 60 years old) or in those taking doses higher than 30 mg daily.
  • Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV.
  • If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Domipen 10 mg Tablet , immediately contact your doctor.
  • Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.
  • Adolescents (children aged 12-18 years) who weigh less than 35 kg should not be given Domipen 10 mg Tablet .

Drug-Drug Interactions

verifiedApollotooltip
DomperidoneClarithromycin
Severe
DomperidoneMethadone
Severe

Drug-Drug Interactions

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DomperidoneClarithromycin
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Domipen 10 mg Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Domipen 10 mg Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Domipen 10 mg Tablet:
Combining Mizolastine with Domipen 10 mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domipen 10 mg Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Nefazodone can increase the blood levels of Domipen 10 mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Domipen 10 mg Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Domipen 10 mg Tablet:
Coadministration of Domipen 10 mg Tablet with Ritonavir can increase the blood levels of Domipen 10 mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Domipen 10 mg Tablet and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
  • Include more cool beverages with your food, such as clear soups, flavoured gelatin, and carbonated beverages. Also, when drinking with a straw, sip slowly to avoid swallowing air, which can lead to gas or acidity.
  • Drink after, or any other liquid, at least 30 minutes after eating. After eating food, lie down for at least after 2 hours.
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Domipen 10 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Drinking alcohol with Domipen 10 mg Tablet may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Unsafe

Domipen 10 mg Tablet is not usually recommended in pregnancy. However, inform your doctor if you are pregnant or planning for pregnancy before taking Domipen 10 mg Tablet .

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Breast Feeding

Unsafe

Domipen 10 mg Tablet is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe if prescribed

Domipen 10 mg Tablet has no effect on your ability to drive or operate machinery.

bannner image

Liver

Caution

Domipen 10 mg Tablet should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them.

bannner image

Kidney

Caution

Domipen 10 mg Tablet should be taken with caution in patients with kidney problems. Your doctor will adjust your dose based on the severity of your condition.

bannner image

Children

Unsafe

Domipen 10 mg Tablet should not be given to adolescents younger than 12 years of age or who are less than 35 kg in weight.

FAQs

Domipen 10 mg Tablet is used to treat nausea (feeling sick) and vomiting (being sick). Besides this, it also helps in the treatment of indigestion.

Domipen 10 mg Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Domipen 10 mg Tablet as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Yes, Domipen 10 mg Tablet can cause dry mouth. If you feel excessively thirsty, please increase your fluid intake and perform frequent mouth rinses.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Domipen 10 mg Tablet may cause side effects such as dry mouth, headache or diarrhoea. If these side effects persist or worsen, please consult your doctor.

If you have any liver or kidney problems, inform your doctor so an alternative treatment can be recommended.

You are recommended to avoid spicy and oily foods. Limit smoking and alcohol consumption as they may worsen the reflux (stomach acid rising into the oesophagus). Also, avoid carbonated drinks, such as cold drinks and soda, as the carbon dioxide gas they contain may worsen acid reflux. Limit your intake of chocolate and mint. Some painkillers, such as Ibuprofen, may increase acidity and worsen the condition. Thus, avoid using these for prolonged durations.

Take Domipen 10 mg Tablet only for the duration as prescribed by your doctor. If you get relief from your symptoms, consult your doctor for a follow-up, where your doctor may lower the dose. Long-term use of Domipen 10 mg Tablet may cause fractures, low vitamin B12 levels and magnesium levels. You need to be cautious about these and continue to monitor your blood levels regularly. If required, your doctor may prescribe supplements to address these deficiencies.

Domipen 10 mg Tablet is contraindicated in patients with a known hypersensitivity to domperidone or any other inactive ingredients of Domipen 10 mg Tablet . Patients with underlying liver or kidney disease should use caution.

Yes, the use of Domipen 10 mg Tablet can cause diarrhoea. If you have diarrhoea, drink plenty of water or other fluids. Avoid consuming fatty or fried foods with Domipen 10 mg Tablet . If diarrhoea persists and you notice any signs of dehydration, such as decreased urination with dark-coloured, strong-smelling urine.

Store Domipen 10 mg Tablet at room temperature in a cool and dry place. Protect from direct light and moisture. Keep it out of reach of children.

Yes, Domipen 10 mg Tablet is safe if used as advised by the doctor. Follow your doctor’s instructions.

It is best to take Domipen 10 mg Tablet before food. Take it the 15 to 30 minutes before a meal or snack or take it as advised by your doctor.

Take Domipen 10 mg Tablet as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

You are recommended to take your doctor’s advice before taking Domipen 10 mg Tablet if you are pregnant or breastfeeding.

Country of origin

India

Manufacturer/Marketer address

409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001
Other Info - DOM0024

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 17, 2025 | 11:04 AM IST

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Reference

  1. https://www.nhs.uk/medicines/domperidone/
  2. https://www.medicines.org.uk/emc/files/pil.556.pdf

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