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  3. Donep-10 Tablet 10's

Donep-10 Tablet 10's, Pack of 10 TABLETS
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Composition :

DONEPEZIL-10MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Donep-10 Tablet

Donep-10 Tablet is used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease. Alzheimer’s disease is a brain condition that slowly damages memory, thinking, learning, and organizing skills. It is the most common cause of dementia, mainly affecting older adults. As the disease progresses, it leads to significant cognitive decline and changes in behaviour and personality.

Donep-10 Tablet contains Donepezil, which works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine. Thereby, it helps treat symptoms of dementia in patients with Alzheimer's disease.

The dose and duration of treatment with Donep-10 Tablet can be determined by the doctor based on your medical condition. In some cases, Donep-10 Tablet may cause side effects such as diarrhoea, nausea, headache, muscle cramps and tiredness. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Do not take Donep-10 Tablet if you are allergic to Donep-10 Tablet or any of its components. Inform the doctor if you have a heart rhythm disorder, a stomach ulcer, urination problems, asthma or other breathing disorders, seizures or liver disease before taking Donep-10 Tablet . Consult the doctor if you are pregnant or breastfeeding before taking Donep-10 Tablet . Also, keep the doctor informed about your health condition and any medications you are taking to rule out any potential side effects or interactions. Donep-10 Tablet should be used for children only if prescribed by the doctor.

Uses of Donep-10 Tablet

Donep-10 Tablet is used to manage cognitive symptoms associated with neurodegenerative disorders. The detailed uses of Donep-10 Tablet are as follows:<br/> • Treatment of dementia symptoms in alzheimer's disease: Donep-10 Tablet is prescribed to improve memory, awareness, and the ability to perform daily functions in individuals with mild to moderate Alzheimer's disease. It works by enhancing communication between nerve cells in the brain.<br/>

Directions for Use

  • Donep-10 Tablet can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Donep-10 Tablet as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

Donep-10 Tablet belongs to the group of medicines called acetylcholinesterase inhibitors used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease. Donep-10 Tablet contains Donepezil, which works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine. Thereby, it helps treat symptoms of dementia in patients with Alzheimer's disease.

How Donep-10 Tablet Works

Donep-10 Tablet contains Donepezil, which works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine. Thereby, it helps treat symptoms of dementia in patients with Alzheimer's disease.

Storage

Store in a cool and dry place away from sunlight
Side effects of Donep-10 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Discuss with your doctor the use of medications like antidiarrheals, laxatives, or stool bulking agents to control bowel movements.
  • Drink enough water to help loosen stool and ease bowel movements.
  • Consume foods high in fiber to encourage regular bowel movements and avoid constipation, such as spinach, bananas, berries, and brown rice.
  • Regular exercises improve bowel functionality and a healthy condition altogether.
  • Do Kegel exercises to strengthen pelvic floor muscles and bowel control.

What if I have taken an overdose of Donep-10 Tablet

Do not take more than the prescribed dose of Donep-10 Tablet , as it may cause an overdose. The symptoms of overdose include vomiting, severe nausea, blurred vision, sweating, drooling, feeling lightheaded, seizures (fits), shallow breathing, slow heartbeat, fainting or muscle weakness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Donep-10 Tablet if you are allergic to Donep-10 Tablet or any of its components. Inform the doctor if you have liver or kidney disease, stomach or duodenal ulcer, seizure or convulsions, heart problems, low levels of potassium or magnesium, lung disease, or extrapyramidal symptoms. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Drug-Drug Interactions

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DonepezilCyclopentolate
Severe
DonepezilMetrizamide
Severe

Drug-Drug Interactions

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DonepezilCyclopentolate
Severe
How does the drug interact with Donep-10 Tablet:
Coadministration of Cyclopentolate with Donep-10 Tablet can reduce the levels and effects of Cyclopentolate.

How to manage the interaction:
There may be a possibility of interaction between Cyclopentolate and Donep-10 Tablet, but it can be taken when prescribed by a doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, or rapid heartbeat consult your doctor immediately. Do not stop using any medications without talking to your doctor.
DonepezilMetrizamide
Severe
How does the drug interact with Donep-10 Tablet:
The combined use of metrizamide and Donep-10 Tablet can increase the risk of developing seizures. If you have a history of seizures or a head injury, contact your doctor immediately.

How to manage the interaction:
Although there is a possible interaction between Donep-10 Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
DonepezilTramadol
Severe
How does the drug interact with Donep-10 Tablet:
Coadministration of Donep-10 Tablet with tramadol can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Taking Donep-10 Tablet with tramadol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, increased heart rate, blurred vision, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DonepezilIomeprol
Severe
How does the drug interact with Donep-10 Tablet:
Co-administration of Iomeprol and Donep-10 Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Co-administration of Donep-10 Tablet with Iomeprol can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not discontinue any medications without first consulting your doctor.
DonepezilIopamidol
Severe
How does the drug interact with Donep-10 Tablet:
The combined use of iopamidol and Donep-10 Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizures or head injury.

How to manage the interaction:
Taking Donep-10 Tablet with Iopamidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not stop using any medications without a doctor's advice.
DonepezilIohexol
Severe
How does the drug interact with Donep-10 Tablet:
Coadministration of Iohexol and Donep-10 Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Although taking Donep-10 Tablet and Iohexol together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
DonepezilBupropion
Severe
How does the drug interact with Donep-10 Tablet:
Taking bupropion with Donep-10 Tablet may increase the levels of Donep-10 Tablet and the risk of developing seizures.

How to manage the interaction:
Co-administration of bupropion along with Donep-10 Tablet can lead to an interaction, but it can be taken when recommended by a doctor. However, if you experience sudden dizziness, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person dealing with Alzheimer's disease needs to take proper nutrition to make their body strong and healthy. For a patient dealing with dementia, poor nutrition can affect behavioral symptoms and may cause weight loss.
  • Consume more whole grains, low-fat dairy products, vegetables, fruits, and lean protein foods, and cut down high saturated fat, refined sugars, and cholesterol from your diet.
  • Patients dealing with dementia should do meditation activities that help calm down their minds and make medicine work more efficiently.
  • Engage in physical exercises like walking, stretching or yoga to enhance mood.
  • Interacting regularly with friends or family can improve mood and mental function.
  • Engage in reading books, puzzles, learning new skills or memory games to stay mentally active.

Habit Forming

No

Therapeutic Class

ANTI- ALZHEIMER'S AGENTS

Donep-10 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advised to avoid alcohol consumption while taking Donep-10 Tablet , as alcohol can worsen dementia symptoms and reduce the effectiveness of the medication.

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Pregnancy

Caution

Please consult the doctor if you are pregnant before taking Donep-10 Tablet . The doctor may prescribe this medication only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Donep-10 Tablet passes into breast milk. Therefore, please consult the doctor if you are breastfeeding before taking Donep-10 Tablet .

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Driving

Caution

Donep-10 Tablet may cause dizziness. Therefore, avoid driving or operate heavy machinery until you are fully alert.

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Liver

Caution

If you have any concerns regarding the use of Donep-10 Tablet in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns about using Donep-10 Tablet in patients with kidney problems, please consult a doctor.

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Children

Caution

Donep-10 Tablet should be used for children only if prescribed by the doctor. Please consult the doctor before using Donep-10 Tablet to your child.

Have a query?

FAQs

Donep-10 Tablet belongs to the group of medicines called acetylcholinesterase inhibitors. It is used to treat the symptoms of dementia in people with mild and moderately severe Alzheimer's disease.

Donep-10 Tablet belongs to the group of medicines called acetylcholinesterase inhibitors. It works by increasing the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine.

Do not stop taking Donep-10 Tablet unless told to do so by your doctor. If you stop taking Donep-10 Tablet , the benefits of your treatment will gradually fade away.

Donep-10 Tablet may cause side effects such as nausea, vomiting, diarrhoea, loss of appetite, muscle cramps, weakness and unusual tiredness. If these side effects persist or worsen, please consult your doctor.

Donep-10 Tablet results in bone weakness and can increase the risk of fractures in elderly patients if taken in high doses for an extended period of time.

Donep-10 Tablet may cause diarrhoea as a common side effect but sometimes can be serious. Donep-10 Tablet reduces the levels of gastric acid and can increase the bacterial count in the gut and can lead to infections. Thus, if you have persistent diarrhoea, consult your doctor immediately.

The long term use of the Donep-10 Tablet results in liver function disturbances, changes in electrolyte (magnesium, calcium and sodium) levels and B12 deficiency. Therefore, if you experience symptoms such as loss of appetite, yellow skin and eyes, nausea, dizziness, itching, fits, headache, tiredness, irritability, or pale skin, consult your doctor immediately. As you have been prescribed Donep-10 Tablet for a long duration, your doctor may recommend regular follow-ups and blood tests.

Yes, you can Donep-10 Tablet on an empty stomach or with food or as advised by your doctor. But take it at the same time every day for best results.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - DON0012

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 8:52 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020690s035,021720s008,022568s005lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.4428.pdf
  3. https://www.drugs.com/mtm/donepezil.html

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