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compositionComposition:AMISULPRIDE-5MG
prescriptionPrescription Medicine

Dopnauz Injection 2 ml is used to treat and prevent postoperative nausea and vomiting. It helps reduce feelings of sickness and prevents vomiting. This improves comfort during recovery and allows better intake of food and fluids.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMISULPRIDE-5MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Dopnauz Injection 2 ml

Dopnauz Injection 2 ml is used to treat and prevent postoperative nausea and vomiting. Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach's contents through the mouth.

Dopnauz Injection 2 ml contains amisulpride, which helps control nausea and vomiting. It acts on brain regions that mediate vomiting and helps prevent nausea. This improves comfort after surgery.

Dopnauz Injection 2 ml will be administered by a healthcare professional. Dopnauz Injection 2 ml may cause common side effects, including dry mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to remain still), Parkinsonism, and increased blood prolactin levels. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Dopnauz Injection 2 ml should be avoided if you are allergic to it or any other medicines. Dopnauz Injection 2 ml is not recommended for children under 18. Let your doctor know if you are pregnant or breastfeeding before receiving Dopnauz Injection 2 ml. Dopnauz Injection 2 ml should be used with extreme caution in elderly patients aged 65 years and older, as there is an increased risk of severe adverse effects.

Uses of Dopnauz Injection 2 ml

Dopnauz Injection 2 ml is used in the treatment and prevention of postoperative nausea and vomiting (PONV). The detailed uses of Dopnauz Injection 2 ml are as follows:

  • Preventing Postoperative Nausea: Dopnauz Injection 2 ml helps prevent nausea after surgery, reducing patient discomfort and promoting smoother recovery.
  • Treating Postoperative Vomiting: Dopnauz Injection 2 ml helps treat vomiting that occurs after surgery, minimising complications and supporting patient well-being.

Key Benefits

  • Helps prevent nausea after surgery.
  • Reduces stomach discomfort and queasiness.
  • Improves tolerance to food and fluids after surgery.
  • Helps control vomiting after surgery.
  • Reduces the risk of dehydration and related complications.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Dopnauz Injection 2 ml will be administered by a healthcare professional.
  • Do not self-administer.

How Dopnauz Injection 2 ml Works

Dopnauz Injection 2 ml contains Amisulpride, which helps restore the balance of certain natural substances in the brain. It relieves nausea by blocking D2 receptors in the brain's chemoreceptor trigger zone (CTZ), which induces vomiting.
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Alcohol

Caution

Avoid consumption of alcohol while receiving Dopnauz Injection 2 ml as it may lead to increased dizziness and drowsiness.

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Pregnancy

Caution

Dopnauz Injection 2 ml should be used in pregnant women only when prescribed by a doctor. If you are pregnant, inform your doctor before starting treatment with Dopnauz Injection 2 ml. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Dopnauz Injection 2 ml should be used by breastfeeding mothers only when prescribed by a doctor. If you are breastfeeding, inform your doctor before starting treatment with Dopnauz Injection 2 ml. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Dopnauz Injection 2 ml may cause dizziness, drowsiness and uncontrolled movements. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Take Dopnauz Injection 2 ml with caution if you have a history of liver diseases/conditions. Your doctor may adjust the dose if required. Dopnauz Injection 2 ml is not recommended for patients with severe liver disease. Inform your doctor immediately if you experience fatigue, loss of appetite, nausea, vomiting, abdominal pain or yellow discolouration of the eyes or skin.

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Kidney

Caution

Dopnauz Injection 2 ml should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular electrolyte monitoring may be required, as it may alter electrolyte levels in the body.

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Children

Unsafe

Dopnauz Injection 2 ml should not be given to children, as its safety and effectiveness have not been established.

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Heart

Caution

Dopnauz Injection 2 ml should be used with caution in patients with heart problems, as it may prolong the QT interval and increase the risk of serious arrhythmias. ECG monitoring and medical supervision are essential prior to initiating treatment.

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Geriatrics

Caution

Geriatric patients can receive Dopnauz Injection 2 ml, but they are more vulnerable to side effects like sedation, low blood pressure, and heart rhythm changes. Lower doses and close monitoring are essential for safe use.

What if I have taken an overdose of Dopnauz Injection 2 ml

Since Dopnauz Injection 2 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or if you are experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

Eating Habits:

  • Eat smaller meals more often to reduce stomach strain.
  • Avoid solid foods until vomiting completely stops.
  • Choose plain, light foods like bread and biscuits.

Fluids:

  • Drink enough fluids to stay hydrated.
  • Use oral rehydration solution (ORS) to replace lost salts.

Food Choices:

  • Avoid fried foods and foods with strong flavours.
  • Avoid foods that may upset the stomach.

Rest and Digestion:

  • Take adequate rest and avoid activity immediately after meals
  • Ginger tea may help support digestion and reduce nausea

Have a query?

How Soon It Starts Working

  • The time required for Dopnauz Injection 2 ml to start to work: The time required for Dopnauz Injection 2 ml to show its action is unknown.
  • The time for which the effects of Dopnauz Injection 2 ml last: The duration of action for Dopnauz Injection 2 ml is unknown.

What if you forget to take Dopnauz Injection 2 ml

Because this medicine will be administered by a healthcare professional, the risk of missing a dose is lower. However, consult your doctor if you have any concerns.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dopnauz Injection 2 ml out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not use Dopnauz Injection 2 ml if you are allergic (hypersensitive) to olanzapine or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), or pituitary tumour.
  • Dopnauz Injection 2 ml should not be given to children as safety has not been established.
  • Use Dopnauz Injection 2 ml with extreme caution in elderly patients above 65 years of age, as there is an increased risk of severe adverse effects.
  • If you are pregnant or breastfeeding, please consult a doctor before taking Dopnauz Injection 2 ml.
  • Dopnauz Injection 2 ml may impair fertility, so inform your doctor if you are planning a pregnancy.
  • Inform your doctor if you are previously diagnosed with kidney disease, liver disease, epilepsy or seizures (fits), Parkinson's disease, unusual heart rate (rhythm), slow heartbeat (less than 55 beats per minute), low potassium levels in your blood, prolonged QT interval (heart conduction problem) if you or someone else in your family has a history of blood clots, heart problems, stroke, diabetes, have a low number of white blood cells (agranulocytosis), leucopenia (blood disorder).
  • Dopnauz Injection 2 ml may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Dopnauz Injection 2 ml as it could lead to increased drowsiness and dizziness.

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Drug-Drug Interaction: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.

  • Heart rhythm medicine – Antiarrhythmic (Dronedarone)
    • Potential effect: May increase the risk of severe irregular heart rhythm and serious cardiac side effects.
  • Stomach-movement medicines (Cisapride, Metoclopramide)
    Potential effect: May increase the risk of irregular heart rhythm, especially in patients with heart problems.
  • Antipsychotic medicines (Pimozide, Ziprasidone)
    Potential effect: May increase the risk of severe irregular heart rhythm and lead to serious side effects.
  • Anti-HIV medicine (Saquinavir)
    Potential effect: May increase the risk of severe irregular heart rhythm.
  • Antibiotic medicine (Grepafloxacin)
    Potential effect: May increase the risk of severe irregular heart rhythm.
  • Antidepressant medicine (Imipramine)
    Potential effect: May increase the risk of irregular heart rhythm, especially in patients with existing heart conditions.
  • Anti-vomiting medicine (Ondansetron)
    Potential effect: May increase the risk of abnormal heart rhythm when used together.

Drug- Food Interaction:

  • Grapefruit juice and Alcohol: Avoid grapefruit juice and alcohol while taking Dopnauz Injection 2 ml, as they may increase the risk of side effects.

Drug-Disease Interaction: Inform your doctor if you have a history of this condition before taking Dopnauz Injection 2 ml.

  • Breast cancer
  • Pheochromocytoma (tumour of the adrenal gland)
  • Pituitary gland prolactinoma (tumour of the pituitary gland)
  • Fits
  • Parkinson’s disease
  • Kidney problems
  • Heart problems

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Dopnauz Injection 2 ml is used to treat Postoperative nausea and vomiting (PONV).

Dopnauz Injection 2 ml contains Amisulpride, which works by modulating certain chemical messengers (dopamine D2) in the brain, which helps regulate nausea and vomiting.

The oral form of Amisulpride can be used to treat psychotic disorders like schizophrenia, bipolar disorder, and depression. However, you should not take this medication without a doctor's advice.

Dopnauz Injection 2 ml may affect fertility as it may cause hyperprolactinemia (excessive levels of prolactin hormone in the blood), resulting in amenorrhea (absence of menstrual periods), anovulation (lack of egg release) and impaired fertility.

Dopnauz Injection 2 ml is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Dopnauz Injection 2 ml.

Stopping Dopnauz Injection 2 ml abruptly can cause withdrawal symptoms, and stopping it too early could make your illness come back. Please consult your doctor if you want to stop taking Dopnauz Injection 2 ml.

Take Dopnauz Injection 2 ml with caution if you have diabetes, as it may increase the risk of having diabetes. It is advised to monitor your blood sugar levels regularly while receiving Dopnauz Injection 2 ml.

Disclaimer

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Author Details

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Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - DOP0054
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