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Dubinor Tablet 10's

Manufacturer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Dubinor Tablet 10's

Dubinor Tablet 10's is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Dubinor Tablet 10's is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Dubinor Tablet 10's helps to treat neuropathic pain.

Take Dubinor Tablet 10's as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Dubinor Tablet 10's may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. The majority of these side effects do not necessitate medical attention and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Please do not take Dubinor Tablet 10's if you are allergic to any of its ingredients. Consult your doctor before taking Dubinor Tablet 10's if you are pregnant or breastfeeding. Dubinor Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Dubinor Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Dubinor Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Dubinor Tablet 10's

Neuropathic pain

Medicinal Benefits

Dubinor Tablet 10's is a combination of three drugs: Methylcobalamin (a form of vitamin B), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Dubinor Tablet 10's is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Dubinor Tablet 10's helps to treat neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dubinor Tablet 10's

  • Constipation
  • Dry mouth
  • Headache
  • Feeling sleepy, tired or dizzy
  • Diarrhoea

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to any of the ingredients in Dubinor Tablet 10's, do not consume it. Please do not stop taking Dubinor Tablet 10's without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Dubinor Tablet 10's unless your doctor has prescribed it. Dubinor Tablet 10's may cause drowsiness and dizziness, therefore drive only if you are alert. Dubinor Tablet 10's is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Dubinor Tablet 10's as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Drug Interactions

Drug-Drug Interactions: Dubinor Tablet 10's may have interaction with antidepressant medications (e.g. duloxetine, sertraline, escitalopram), pain killer medications (e.g. codeine, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant medications (e.g. topiramate), anti-anxiety medications (e.g. alprazolam), sedative-hypnotics medications (e.g. zolpidem), antihistamine medications (e.g. diphenhydramine, cetirizine), muscle relaxant medications (e.g. cyclobenzaprine), antiemetic medications (e.g. ondansetron), and herbal medications to treat depression (e.g. St John's wort).

Drug-Food Interactions: Avoid alcohol consumption while taking Dubinor Tablet 10's as it might cause increased drowsiness and sleepiness.

Drug-Disease Interactions: Use Dubinor Tablet 10's with medical advice if you have had anticholinergic effects, cardiovascular disease, pheochromocytoma, acute myocardial infarction recovery, cardiovascular disease, depression, seizure disorders, drug dependence, suicidal tendency, angioedema, creatine kinase elevations, peripheral oedema, PR interval prolongation, bone marrow suppression, diabetes, renal/liver disease, schizophrenia/bipolar disorder, hyper/hypoglycemia, schizophrenia, thyroid disorders and urinary retention.

Safety Advice

  • Safety Warning

    Alcohol

    Consult Your Doctor

    Avoid consumption of alcohol while taking Dubinor Tablet 10's as it may increase drowsiness and sleepiness.

  • Safety Warning

    Pregnancy

    If you're pregnant, don't take Dubinor Tablet 10's unless your doctor tells you to. Please consult your doctor if you have any concerns about this; your doctor will only prescribe if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    Consult your doctor as there is no substantial research yet on the use of Dubinor Tablet 10's in breastfeeding/nursing mothers.

  • Safety Warning

    Driving

    Consult Your Doctor

    Dubinor Tablet 10's causes drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

  • Safety Warning

    Liver

    Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Kidney

    Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

Habit Forming

No

Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.
  • Cayenne pepper should be included in your diet because it can help with neuropathic pain.
  • Exercising regularly helps to improve overall health and combat pain.
  • Rest well and get plenty of rest.
  • Taking a warm bath can be very relaxing.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can reduce stress, pain sensitivity and improve coping skills.
  • Acupuncture, by stimulating pressure points, can be beneficial.
  • Massages with essential oils can help increase circulation.

Special Advise

Dubinor Tablet 10's contains Nortriptyline (antidepressant), which can lead to suicidal thoughts. Suicidal thoughts or behaviour should be closely monitored in people taking Dubinor Tablet 10's. If you have suicidal thoughts, don't be afraid to talk to your doctor right away.

Other Information (DUB0019)

This item is Not Returnable.

Expires on or after - Mar-23

Patients Concern

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also familiar with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury. The body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

FAQs

Dubinor Tablet 10's contains Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Dubinor Tablet 10's helps to treat neuropathic pain.

Dubinor Tablet 10's contains pregabalin. It may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Dubinor Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not stop taking Dubinor Tablet 10's without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Dubinor Tablet 10's for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Dubinor Tablet 10's, do not be afraid to speak with your doctor.

Dubinor Tablet 10's is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.

Dubinor Tablet 10's may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

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Country Of Origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Disclaimer

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(Inclusive of all taxes)

Provide Delivery Location

Strip

1

10 Tablet in 1 Strip