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  1. Home
  2. Medicine

  3. DUOFLAM TABLET

Prescription drug
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DUOFLAM TABLET, Pack of 15 TABLETS
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Extra 15% Off with Bank Offers

Composition :

IBUPROFEN-400MG + PARACETAMOL-500MG

Manufacturer/Marketer :

Svizera Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DUOFLAM TABLET

DUOFLAM TABLET is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever. Pain can be temporary (acute) or long-lasting (chronic).

DUOFLAM TABLET contains Ibuprofen and Paracetamol. This medicine works by blocking the effect of prostaglandin, which is responsible for inducing pain and inflammation in the body.

Like all medicines, DUOFLAM TABLET may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, or any signs of hypersensitivity.

Inform your doctor if you are allergic to any of the components present in it. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Avoid consumption of alcohol as it may damage your liver and cause increased side effects on taking this drug.

Uses of DUOFLAM TABLET

DUOFLAM TABLET is used for the treatment of Pain and Fever. The detailed uses of DUOFLAM TABLET are as follows:

  • Pain Relief: DUOFLAM TABLET is widely used to alleviate mild to moderate pain, such as headaches, toothaches, menstrual cramps, and muscle aches.
  • Fever Reduction: Combining Ibuprofen and Paracetamol, DUOFLAM TABLET effectively reduces fever caused by infections or other health conditions.
  • Anti-inflammatory Benefits: Its anti-inflammatory properties make DUOFLAM TABLET valuable for managing inflammation and swelling in conditions like arthritis and other inflammatory diseases.
  • Post-Surgical Pain Management: DUOFLAM TABLET is often prescribed to manage pain and discomfort following surgical procedures, aiding recovery.
  • Managing Chronic Pain: DUOFLAM TABLET is sometimes included in chronic pain management plans, particularly for conditions like osteoarthritis or persistent back pain, under a healthcare professional's supervision.

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Directions for Use

  • DUOFLAM TABLET should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow DUOFLAM TABLET as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • DUOFLAM TABLET is prescribed mainly to treat pain and relieve discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains.
  • DUOFLAM TABLET comprises Ibuprofen and Paracetamol, primarily used to treat mild to moderate pain.
  • Ibuprofen works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in the body.
  • Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of prostaglandin by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat.
  • Paracetamol has the advantage of producing less gastric irritation than other painkillers like aspirin.

How DUOFLAM TABLET Works

DUOFLAM TABLET is composed of two medicines, namely Ibuprofen and Paracetamol. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together, these two medicines help reduce mild to moderate pain in a shorter duration.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Duoflam Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of DUOFLAM TABLET

Do not take more than the prescribed dose of DUOFLAM TABLET as it may cause severe side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Caution is advised in people with underlying sensitivity to aspirin and other painkillers.
  • DUOFLAM TABLET is contraindicated in children below 12 years of age, weighing under 40 kg.
  • If treatment is required for more than three days, consult your doctor.
  • DUOFLAM TABLET should be taken with caution if you have an allergy to paracetamol, ibuprofen, aspirin, or other pain killers, highly sensitive reactions (asthma, lip/face/throat swelling), existing stomach ulcer or bleeding associated pain killers, blood clotting disorder, heart diseases (like congestive heart failure), kidney disease, peptic ulcer, another active bleeding (like brain stroke bleeding), and severe dehydration (due to vomiting, diarrhea).
  • Liver damage might occur if taken for a longer duration, as it contains paracetamol.
  • The skin should be closely monitored as skin allergic reactions like Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) have been reported with DUOFLAM TABLET.
  • Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with DUOFLAM TABLET, especially in people affected with high blood pressure and who have a history of heart failure.
  • Consult your doctor if your pain, inflammation, and fever symptoms do not disappear even after ten days.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacMethotrexate
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Duoflam Tablet:
Co-administration of Duoflam Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Duoflam Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacMethotrexate
Severe
How does the drug interact with Duoflam Tablet:
Co-administration of methotrexate with Duoflam Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Duoflam Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacTenofovir disoproxil
Severe
How does the drug interact with Duoflam Tablet:
Co-administration of Duoflam Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Duoflam Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacIndometacin
Severe
How does the drug interact with Duoflam Tablet:
The combined use of Duoflam Tablet and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Duoflam Tablet and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacCelecoxib
Severe
How does the drug interact with Duoflam Tablet:
Co-administration of Duoflam Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Duoflam Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacOxaprozin
Severe
How does the drug interact with Duoflam Tablet:
Taking Duoflam Tablet and oxaprozin can increase the risk of side effects.

How to manage the interaction:
Co-administration of Duoflam Tablet and oxaprozin can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacLeflunomide
Severe
How does the drug interact with Duoflam Tablet:
Co administration of Duoflam Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Duoflam Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Duoflam Tablet:
Co-administration of Duoflam Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Duoflam Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacKetorolac
Severe
How does the drug interact with Duoflam Tablet:
Coadministration of Duoflam Tablet and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Duoflam Tablet and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetoconazole
Severe
How does the drug interact with Duoflam Tablet:
Coadministration of Duoflam Tablet with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between Duoflam Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic exercises like walking on the treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

DUOFLAM TABLET Substitute

Substitutes safety advice
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Alcohol

Unsafe

Taking DUOFLAM TABLET with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with DUOFLAM TABLET.

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Pregnancy

Unsafe

Use of DUOFLAM TABLET during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

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Breast Feeding

Consult your doctor

Take DUOFLAM TABLET only if prescribed by your doctor.

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Driving

Unsafe

After taking DUOFLAM TABLET you may notice dizziness, sleepiness, drowsiness or fatigue.

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Liver

Caution

DUOFLAM TABLET to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

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Kidney

Caution

DUOFLAM TABLET to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

DUOFLAM TABLET is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

FAQs

DUOFLAM TABLET is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever.

DUOFLAM TABLET is comprised of two medications, Ibuprofen and Paracetamol. DUOFLAM TABLET has analgesic and anti-inflammatory properties that help relieve mild to moderate pain. DUOFLAM TABLET functions by inhibiting the production of specific chemical messengers that induce fever, discomfort, and inflammation (redness and swelling).

No, it is not advisable to take DUOFLAM TABLET with depression medication. Please inform your doctor if you are taking depression medicine before starting DUOFLAM TABLET.

Yes, DUOFLAM TABLET is a short term medication and if you feel better you can stop taking DUOFLAM TABLET, but only after consulting your doctor.

DUOFLAM TABLET is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.

Yes, DUOFLAM TABLET is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take DUOFLAM TABLET as it can be harmful.

No, DUOFLAM TABLET is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer, or gastric bleeding. Do not take DUOFLAM TABLET in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.

It depends on whether your cough and cold pills contain ibuprofen and paracetamol or not. If it contains these two medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

DUOFLAM TABLET is known to cause stomach upset in some cases. So, please take DUOFLAM TABLET with a meal or a glass of milk to avoid upset stomach.

No, DUOFLAM TABLET should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of DUOFLAM TABLET, please take it in doses and duration mentioned by your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

29-33, Ancillary Industrial Plots Govandi Mumbai MH 400043 INDIA
Other Info - DUO0036

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 8, 2025 | 11:52 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.7020.pdf
  2. https://www.medicines.org.uk/emc/files/pil.1958.pdf
  3. https://www.ciplamed.com/content/ibugesic-plus-oral-suspension
  4. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwjdjZ6y3fXsAhVD6XMBHfAoDaYQFjAAegQIAxAC&url=https%3A%2F%2Fwww.sanofi.in%2F-%2Fmedia%2FProject%2FOne-Sanofi-Web%2FWebsites%2FAsia-Pacific%2FSanofi-IN%2FHome%2Fscience-and-innovation%2Ffor-healthcare-professionals%2Fproduct-information%2FCombiflam-tablets-PI_08072019.pdf&usg=AOvVaw0eY32ELNXM94knsmS25x-D

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