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Duonase Nasal Spray 9.8 ml is a combination medicine, used in the treatment of allergies. This medicine works by inhibiting the inflammatory-causing chemical substances and thereby helps provide relief from a blocked or runny nose, sneezing, itching, watery eyes and an itchy nose. Common side effects include headaches, nausea, vomiting, sore throat, nose bleeds, trouble breathing, cough, burning, or itching.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Nasal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Duonase Nasal Spray 9.8 ml

Duonase Nasal Spray 9.8 ml is a prescription nasal spray used to treat the symptoms of seasonal and year-round allergies. It is designed to ease moderate-to-severe nasal allergy symptoms, such as congestion, sneezing, itching, and a runny nose. By targeting these symptoms directly in the nasal passages, it helps restore your comfort during high-allergy seasons.

For the best results, use this nasal spray daily and consistently as directed by your healthcare provider. Since it is applied directly inside your nose, you can use it with or without food. Simple measures, such as using dust-proof mattress covers or keeping windows closed when pollen counts are high, can further improve symptom control.

Many people experience only mild, temporary side effects, such as a bitter taste in the mouth or brief nasal irritation. However, if you develop severe nosebleeds, persistent pain inside your nose, or changes in your vision, contact your doctor promptly.

Do not use this medicine if you have had a recent nasal injury, nasal surgery, or untreated nasal ulcers until your nose has fully healed. Before starting this medicine, tell your doctor if you have tuberculosis, an untreated fungal, bacterial, or viral infection, or a history of glaucoma or cataracts.

This nasal spray may interact with certain medicines, including strong antiviral or antifungal medicines that can increase steroid exposure in your body. Also tell your doctor if you are pregnant, breastfeeding, planning to become pregnant, or caring for an older adult before starting treatment.

Uses of Duonase Nasal Spray 9.8 ml

This medicine is used to relieve the symptoms of allergic rhinitis and reduce inflammation in the nasal passages. The detailed uses of this medicine are as follows:

  • Allergic rhinitis (seasonal and perennial): Duonase Nasal Spray 9.8 ml helps reduce the nasal swelling, congestion, runny nose, and sneezing caused by pollen, mold, dust mites, and pet dander.
  • Nasal passage inflammation: Duonase Nasal Spray 9.8 ml targets and calms severe inflammation inside the nasal lining, making it easier to breathe through your nose during the day and night.

Key Benefits

This medicine provides both symptom relief and long-term control of nasal allergy inflammation. Its benefits include:

  • Helps relieve nasal congestion, sneezing, runny nose, and nasal itching.
  • Reduces inflammation and swelling inside the nasal passages, making breathing easier.
  • Helps improve sleep quality by reducing nighttime nasal blockage.
  • Combines an antihistamine and a corticosteroid to provide comprehensive allergy relief.
  • Delivers medicine directly to the nasal tissues, helping minimize whole-body side effects.
  • Supports better daily comfort and productivity by providing long-lasting allergy symptom relief.
Side effects of Duonase Nasal Spray 9.8 ml
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Insert the tip of the bottle into one nostril, close the other nostril, and spray toward the sides of the nostril.
  • Keep your head straight and breathe gently.
  • Always shake the bottle before each use.

How Duonase Nasal Spray 9.8 ml Works

Duonase Nasal Spray 9.8 ml contains Azelastine Hydrochloride and Fluticasone Propionate. Azelastine Hydrochloride: It is an antihistamine that blocks the action of histamine, a chemical released during allergic reactions. This helps relieve sneezing, runny nose, nasal itching, and other allergy symptoms. Fluticasone Propionate: It is a corticosteroid that reduces inflammation and swelling inside the nasal passages. It helps relieve nasal congestion and provides long-lasting control of allergy symptoms when used regularly.
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Alcohol

Unsafe

Avoid consumption of alcohol with Duonase Nasal Spray 9.8 ml as it may increase adverse effects. Please consult a doctor before consuming alcohol with Duonase Nasal Spray 9.8 ml.

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Pregnancy

Consult your doctor

The safety of Duonase Nasal Spray 9.8 ml in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor before using Duonase Nasal Spray 9.8 ml if you are breastfeeding.

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Driving

Unsafe

Duonase Nasal Spray 9.8 ml may cause drowsiness in some people. Therefore, drive only if you are alert after using Duonase Nasal Spray 9.8 ml.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before using Duonase Nasal Spray 9.8 ml.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before using Duonase Nasal Spray 9.8 ml.

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Children

Caution

Duonase Nasal Spray 9.8 ml is not recommended for children under 6 years old, as its safety and effectiveness have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Duonase Nasal Spray 9.8 ml. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Duonase Nasal Spray 9.8 ml should be used with caution in elderly patients, starting at a lower dose because of potentially decreased organ function. Consult your doctor if you have any concerns.

What if I have taken an overdose of Duonase Nasal Spray 9.8 ml

Using too much of this nasal spray is unlikely to cause severe or life-threatening symptoms. However, if someone accidentally swallows the contents of the bottle or uses an extremely large amount, seek immediate medical attention or contact your local poison control center.

Diet & Lifestyle Advise

  • Use a saline nasal rinse: Rinse your nose with a saline solution 15 to 30 minutes before using Duonase Nasal Spray 9.8 ml to help clear mucus and improve contact with the nasal lining.
  • Stay well-hydrated: Drink plenty of water throughout the day to help keep your nasal passages moist and reduce dryness.
  • Reduce indoor allergens: Use allergen-proof covers on pillows and mattresses, clean your home regularly, and vacuum carpets to minimize exposure to dust and other allergens.
  • Limit pollen exposure: Check local pollen forecasts and stay indoors with windows closed when pollen levels are high to help reduce allergy symptoms.
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Have a query?

How Soon It Starts Working

  • The time required for Duonase Nasal Spray 9.8 ml to start to work: Duonase Nasal Spray 9.8 ml ideally shows its action within 5 to 15 minutes after administration.
  • The time for which the effects of Duonase Nasal Spray 9.8 ml last: The effect of Duonase Nasal Spray 9.8 ml lasts for 12 hours.

What if you forget to take Duonase Nasal Spray 9.8 ml

If you miss a dose of Duonase Nasal Spray 9.8 ml, use it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not use a double dose to make up for a missed one.

Storage

•Store Duonase Nasal Spray 9.8 ml upright at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Store it safely out of the reach of children and pets.

Drug Warnings

  • Shake the bottle before use: Gently shake the bottle before each use to ensure the active ingredients are evenly mixed.
  • Avoid contact with the eyes and mouth: Do not spray Duonase Nasal Spray 9.8 ml into your eyes or mouth. If it accidentally gets into your eyes, rinse them thoroughly with cool water.
  • Do not share the nasal spray: Never share your nasal spray bottle with others, as this may spread germs and increase the risk of infection.
  • Clean the spray nozzle regularly: Rinse the spray nozzle with warm water once a week and allow it to air dry completely. If the nozzle becomes clogged, soak it in warm water and rinse again. Do not use pins, needles, or other sharp objects to clear the opening, as this may damage the spray mechanism and affect the accuracy of each dose.
  • Avoid alcohol and sedatives: Avoid drinking alcohol or taking other medicines that cause drowsiness unless advised by your doctor, as this spray may make some people feel sleepy.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong antiviral and antifungal medicines: May increase steroid levels in your body and raise the risk of side effects.
  • Other antihistamines or CNS depressants: May increase drowsiness and reduce alertness.

Drug-Drug Interactions

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How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although taking Azelastine and Fluticasone with Desmopressin is not recommended, as it can lead to an interaction it can be taken if prescribed by doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Mifepristone may make Fluticasone less effective as a therapy.

How to manage the interaction:
Taking Azelastine and Fluticasone with Mifepristone is not recommended, as it can lead to an interaction it can be taken if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
Critical
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Taking Azelastine and Fluticasone with Sodium oxybate may increase the blood levels of Azelastine leading to risk of side effects.

How to manage the interaction:
Taking Azelastine and Fluticasone together with Sodium oxybate is generally not recommended as it result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Nefazodone may significantly increase the absorption of Fluticasone into the bloodstream may increase the risk of side effects.

How to manage the interaction:
Co-administration of Azelastine and Fluticasone with Nefazodone can possibly result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, impairment in thinking, judgment, and motor coordination. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Troleandomycin may significantly increase the absorption of Fluticasone and tend to increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Azelastine, Fluticasone and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Atazanavir may significantly increase the absorption of Fluticasone into the bloodstream, that may increase the risk of side effects.

How to manage the interaction:
Co-administration of Azelastine and Fluticasone with Atazanavir can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Saquinavir may increase the absorption of Fluticasone into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although taking Azelastine and Fluticasone together with Saquinavir can possibly result in an interaction, it can be taken if a doctor has advised it However, if you experience side effects such as weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone together with Itraconazole may significantly increase the absorption of fluticasone into the bloodstream that may increase the risk of side effects.

How to manage the interaction:
Although taking Azelastine and Fluticasone together with Itraconazole can possibly result in an interaction, it can be taken if a doctor has advised it. Consult a prescriber if you experience symptoms such as Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts, irregular menstruation, and excessive face or body hair growth. Do not discontinue taking a medication without consulting a doctor.
Severe
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Delavirdine may significantly increase the absorption of Fluticasone into the bloodstream that may increase the risk of side effects.

How to manage the interaction:
Although taking Azelastine and Fluticasone with Delavirdine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Duonase Nasal Spray 9.8 ml:
Co-administration of Azelastine and Fluticasone with Amprenavir may significantly increase the absorption of fluticasone into the blood stream which may increase the risk of side effects.

How to manage the interaction:
Co-administration of Azelastine and Fluticasone with Amprenavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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  • Alcohol: May increase drowsiness, sleepiness, or impaired concentration. Avoid or limit alcohol unless advised otherwise by your doctor.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Duonase Nasal Spray 9.8 ml is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes.
Duonase Nasal Spray 9.8 ml contains Fluticasone propionate and Azelastine hydrochloride. Fluticasone propionate works by acting on cells in the nasal lining and inhibiting the release of certain chemicals that trigger inflammatory reactions. Thereby provides relief from sneezing, a runny or blocked nose, and sinus discomfort. Azelastine hydrochloride is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance that triggers allergic reactions.
You are recommended to avoid using grapefruit and grapefruit juice with Duonase Nasal Spray 9.8 ml as they may lead to adrenal insufficiency and Cushing’s syndrome.
You are not recommended to take more than the prescribed dose of Duonase Nasal Spray 9.8 ml or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while using Duonase Nasal Spray 9.8 ml, please consult a doctor immediately.
Duonase Nasal Spray 9.8 ml is not intended for the treatment of asthma attacks. Duonase Nasal Spray 9.8 ml is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.
You should avoid using Duonase Nasal Spray 9.8 ml and consult a doctor before using Duonase Nasal Spray 9.8 ml if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.
Yes. Although nasal sprays generally cause less drowsiness than oral antihistamines, some people may still experience sleepiness or drowsiness while using Duonase Nasal Spray 9.8 ml. The risk may be higher if you drink alcohol. Avoid driving, operating machinery, or performing tasks that require full alertness until you know how the medicine affects you. If drowsiness persists or interferes with your daily activities, consult your doctor.
Use Duonase Nasal Spray 9.8 ml as directed by the doctor. Read the label for proper instructions before use. Insert the nozzle into one nostril, close the other nostril, and spray toward the sides of the nostril. Keep your head straight and breathe gently. Repeat for the other nostril.
Duonase Nasal Spray 9.8 ml should be stored in a cool, dry place, away from sunlight. Keep it out of sight and reach of children.
The side effects of Duonase Nasal Spray 9.8 ml include taste changes, nose bleeds and headaches. Consult the doctor if any of these side effects persist or worsen.
You should use this medicine during pregnancy only if your doctor determines that the expected benefits outweigh the potential risks. Do not start, stop, or change your treatment on your own during pregnancy. Your doctor can help you weigh the available treatment options, including alternatives when appropriate, to ensure the safest approach for you and your baby.
Many patients begin to experience relief from nasal allergy symptoms within 30 minutes of using Duonase Nasal Spray 9.8 ml. However, the full anti-inflammatory benefits of the steroid component can take several days of consistent use to develop. Talk to your doctor if your symptoms do not improve after a week of daily use.
A bitter taste is a common and harmless side effect of the antihistamine component in the spray. You can minimize this by keeping your head tilted slightly forward while spraying and avoiding sniffing too hard. Talk to your doctor or pharmacist if the taste becomes highly bothersome.
You should consult your healthcare provider before combining Duonase Nasal Spray 9.8 ml with other allergy treatments, especially other antihistamines or steroid sprays, to avoid unnecessary side effects. Talk to your doctor to design a safe, coordinated treatment plan.
Mild, temporary stinging or burning can occur when you first apply the spray. However, if the burning is severe, persistent, or leads to frequent nosebleeds, stop using the spray and talk to your doctor.
Yes, cleaning the nozzle once a week helps prevent clogs and ensures a consistent, fine mist. Gently pull the plastic nozzle off, rinse it under warm tap water, let it air dry completely, and pop it back onto the bottle. Talk to your pharmacist if you are unsure how to clean your device safely.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DUO0008
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