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  3. Durataf 25 Tablet 30's

Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
DURATAF 25MG TABLET is used to treat chronic hepatitis B virus (HBV) infection. It contains Tenofovir alafenamide which works by inhibiting HBV replication and clears the infection. In some cases, this medicine may cause side effects like headaches, diarrhoea, nausea, vomiting, and rash. Keep the doctor informed about your health condition and the medications you are taking.
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Composition :

TENOFOVIR ALAFENAMIDE-25MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About DURATAF 25MG TABLET

DURATAF 25MG TABLET belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

DURATAF 25MG TABLET contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take DURATAF 25MG TABLET as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of DURATAF 25MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using DURATAF 25MG TABLET as it may cause dizziness, affecting your ability to drive or use machines. Should not use DURATAF 25MG TABLET for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Uses of DURATAF 25MG TABLET

Treatment of Chronic hepatitis B

Directions for Use

• DURATAF 25MG TABLET can be taken with meals for better effectiveness.• It is usually taken once daily or as advised by your doctor.• Swallow DURATAF 25MG TABLET as a whole with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

DURATAF 25MG TABLET ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

How DURATAF 25MG TABLET Works

DURATAF 25MG TABLET contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Storage

Keep DURATAF 25MG TABLET out of reach and sight of children.
Side effects of Durataf 25 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of DURATAF 25MG TABLET

Take DURATAF 25MG TABLET only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using DURATAF 25MG TABLET as DURATAF 25MG TABLET may cause dizziness, affecting your ability to drive or use machines. DURATAF 25MG TABLET is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug-Drug Interactions

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Tenofovir alafenamideCidofovir
Critical
Tenofovir alafenamideRifabutin
Severe

Drug-Drug Interactions

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Tenofovir alafenamideCidofovir
Critical
How does the drug interact with Durataf 25 Tablet:
Coadministration of Cidofovir and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cidofovir and Durataf 25 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir alafenamideRifabutin
Severe
How does the drug interact with Durataf 25 Tablet:
Taking Rifabutin and Durataf 25 Tablet may significantly reduce the blood levels of tenofovir which may make it less effective.

How to manage the interaction:
Taking Durataf 25 Tablet with Rifabutin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideMefenamic acid
Severe
How does the drug interact with Durataf 25 Tablet:
The combined use of Mefenamic acid and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Mefenamic acid and Durataf 25 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideRifampicin
Severe
How does the drug interact with Durataf 25 Tablet:
Taking Durataf 25 Tablet with rifampin may lower the Durataf 25 Tablet levels in your blood, possibly decreasing its effectiveness in treating your condition.

How to manage the interaction:
Although taking Rifampicin together with Durataf 25 Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideZoledronic acid
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Zoledronic acid and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Zoledronic acid and Durataf 25 Tablet together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideMeloxicam
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Meloxicam with Durataf 25 Tablet together can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Meloxicam with Durataf 25 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - feeling sick, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideCelecoxib
Severe
How does the drug interact with Durataf 25 Tablet:
Taking celecoxib with Durataf 25 Tablet may increase risk of kidney problems.

How to manage the interaction:
Although taking Celecoxib and Durataf 25 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideAmphotericin b
Severe
How does the drug interact with Durataf 25 Tablet:
Durataf 25 Tablet can cause kidney problems and taking it with amikacin, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Amphotericin b and Durataf 25 Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
Tenofovir alafenamideCiclosporin
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Durataf 25 Tablet with ciclosporin may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction, Durataf 25 Tablet can be taken with ciclosporin if prescribed by the doctor. However, consult the doctor if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
Tenofovir alafenamidevalacyclovir
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Durataf 25 Tablet with valacyclovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Durataf 25 Tablet and valacyclovir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased urination, weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet that includes fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish.
  • Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

DURATAF 25MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid drinking alcohol. Consuming alcohol while using DURATAF 25MG TABLET may worsen the condition.

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Pregnancy

Caution

DURATAF 25MG TABLET is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take DURATAF 25MG TABLET without the doctor's advice.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of DURATAF 25MG TABLET in breastfeeding/nursing mothers.

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Driving

Caution

DURATAF 25MG TABLET can cause dizziness. If you feel dizzy when taking DURATAF 25MG TABLET , do not drive and use any tools or machines.

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Liver

Caution

Consult your doctor before taking DURATAF 25MG TABLET if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Kidney

Caution

Consult your doctor before taking DURATAF 25MG TABLET if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Children

Unsafe

Should not use DURATAF 25MG TABLET in children below 12 years of age.

Have a query?

FAQs

DURATAF 25MG TABLET belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection.

DURATAF 25MG TABLET contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.

No, DURATAF 25MG TABLET is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.

DURATAF 25MG TABLET should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.

A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.

Practising safe sex and other lifestyle changes along with DURATAF 25MG TABLET might lower the risk of HIV transmission. However, it may not prevent the spread of hepatitis B virus (HBV) to other people.

DURATAF 25MG TABLET should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Yes, DURATAF 25MG TABLET is safe if taken in the dose and duration prescribed by the doctor.

DURATAF 25MG TABLET should be swallowed as a whole with water; do not crush or chew it.

Take another dose of DURATAF 25MG TABLET if you have vomited within an hour of taking the medicine. However, you may not need to take another dose if it has been more than an hour. Take the next dose at the scheduled time.

If you miss a dose of DURATAF 25MG TABLET take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

DURATAF 25MG TABLET may cause side effects like headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - DUR0251

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 6:53 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208464s008lbl.pdf
  2. https://www.ema.europa.eu/en/documents/product-information/vemlidy-epar-product-information_en.pdf
  3. https://www.medicines.org.uk/emc/medicine/32756#gref
  4. https://www.nhs.uk/conditions/hepatitis-b/

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