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  3. Duvanta NP 40 Tablet 10's

Duvanta NP 40 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Duvanta NP 40 Tablet is used to treat neuropathic pain. It contains Duloxetine and Mecobalamin which help rejuvenate and protect damaged nerve cells by producing myelin. In some cases, this medicine may cause side effects such as nausea, constipation, headache, drowsiness, dry mouth, difficulty sleeping, and low sexual desire. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

DULOXETINE-40MG + MECOBALAMIN-500MCG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Duvanta NP 40 Tablet

Duvanta NP 40 Tablet is used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, and it is felt as a prickling, stabbing, tingling, or burning sensation.

Duvanta NP 40 Tablet is a combination of two medicines: Duloxetine (mood stabilizer) and Mecobalamin (vitamin B12). Duloxetine is a serotonin-noradrenaline reuptake inhibitor (SNRI). It works by enhancing the amount of mood-enhancing chemicals serotonin and noradrenaline in the brain. This Duvanta NP 40 Tablet action balances out negative emotions, improves mood and sleep, and makes a person live a better life. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a myelin substance. Together, Duvanta NP 40 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Take Duvanta NP 40 Tablet as prescribed. You are advised to take Duvanta NP 40 Tablet as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, constipation, headache, drowsiness, dry mouth, insomnia (difficulty in sleeping), erectile dysfunction, and low sexual desire. Most of these side effects of Duvanta NP 40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Duvanta NP 40 Tablet for as long as your doctor has prescribed. Please do not stop taking Duvanta NP 40 Tablet without consulting your doctor, as it could cause withdrawal symptoms. Keep your doctor informed about your health condition and medicines to rule out any side effects. Duvanta NP 40 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Duvanta NP 40 Tablet as it could lead to increased dizziness and sleepiness. Do not take Duvanta NP 40 Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Inform your doctor immediately if you experience suicidal thoughts after taking Duvanta NP 40 Tablet . Also, seek medical help immediately if you have serotonin syndrome symptoms, such as agitation, hallucinations, fever, shivering, muscle stiffness, twitching, nausea, vomiting, or diarrhoea.

Uses of Duvanta NP 40 Tablet

Treatment of Neuropathic pain

Directions for Use

• Duvanta NP 40 Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Duvanta NP 40 Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Duvanta NP 40 Tablet is used to treat neuropathic pain in adults. Duvanta NP 40 Tablet is a combination of two medicines: Duloxetine (mood stabilizer) and Mecobalamin (vitamin B12). Gabapentin treats seizures by balancing a chemical messenger in the brain called a neurotransmitter, thereby decreasing its abnormal excitement in the brain. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a myelin substance. Together, Duvanta NP 40 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

How Duvanta NP 40 Tablet Works

Duvanta NP 40 Tablet is a combination of two medicines: Duloxetine (mood stabilizer) and Mecobalamin (vitamin B12). Duloxetine is a serotonin-noradrenaline reuptake inhibitor (SNRI). It works by enhancing the amount of mood-enhancing chemicals serotonin and noradrenaline in the brain. This Duvanta NP 40 Tablet action balances out negative emotions, improves mood and sleep, and makes a person live a better life. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a myelin substance. Together, Duvanta NP 40 Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Storage

Keep Duvanta NP 40 Tablet out of the sight and reach of children.
Side effects of Duvanta NP 40 Tablet
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Duvanta NP 40 Tablet

Take Duvanta NP 40 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Duvanta NP 40 Tablet if you are allergic to any of its contents. Inform your doctor before taking Duvanta NP 40 Tablet if you have liver or kidney disease, slow digestion, bleeding problems, narrow-angle glaucoma, bipolar disorder. Avoid taking Duvanta NP 40 Tablet within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, methylene blue injection, linezolid, phenelzine, selegiline, or tranylcypromine. Please do not stop taking Duvanta NP 40 Tablet without consulting your doctor as it could cause withdrawal symptoms. Duvanta NP 40 Tablet causes drowsiness and dizziness, so drive only if you are alert. Duvanta NP 40 Tablet should not be given to children as safety and effectiveness have not been established. Consult your doctor immediately if you experience suicidal tendencies. Do not take Duvanta NP 40 Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Do not get up too fast from a sitting or lying position. Please do not drink alcohol as it may increase your risk of liver damage.

Drug-Drug Interactions

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DuloxetineProcarbazine
Critical
DuloxetineEliglustat
Critical

Drug-Drug Interactions

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DuloxetineProcarbazine
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Taking Duvanta NP 40 Tablet with procarbazine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Duvanta NP 40 Tablet with Procarbazine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineEliglustat
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Coadministration of eliglustat and Duvanta NP 40 Tablet can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Duvanta NP 40 Tablet with Eliglustat is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, or weak pulse. Do not discontinue any medications without consulting your doctor.
DuloxetineRasagiline
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Taking Rasagiline with Duvanta NP 40 Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Rasagiline and Duvanta NP 40 Tablet is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineTranylcypromine
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Taking Tranylcypromine with Duvanta NP 40 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Duvanta NP 40 Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetinePhenelzine
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Taking phenelzine with Duvanta NP 40 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Duvanta NP 40 Tablet with Phenelzine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineMetoclopramide
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Coadministration of metoclopramide with Duvanta NP 40 Tablet increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metoclopramide with Duvanta NP 40 Tablet is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
DuloxetineSelegiline
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Taking Duvanta NP 40 Tablet with selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Duvanta NP 40 Tablet and Selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineSafinamide
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Coadministration of safinamide with Duvanta NP 40 Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Safinamide with Duvanta NP 40 Tablet is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineLinezolid
Critical
How does the drug interact with Duvanta NP 40 Tablet:
Taking Duvanta NP 40 Tablet with Linezolid can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Duvanta NP 40 Tablet with Linezolid is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
DuloxetineLomitapide
Severe
How does the drug interact with Duvanta NP 40 Tablet:
Coadministration of Duvanta NP 40 Tablet and lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Duvanta NP 40 Tablet with Lomitapide can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, itching, fatigue, abdominal pain, dark urine, pale stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet to improve nerve health and prevent nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, and get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreasing numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Duvanta NP 40 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Duvanta NP 40 Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Duvanta NP 40 Tablet ; your doctor will decide whether Duvanta NP 40 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Duvanta NP 40 Tablet causes drowsiness, sleepiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Duvanta NP 40 Tablet should not be given to children and adolescents aged less than 18 years of age.

Have a query?

FAQs

Duvanta NP 40 Tablet is used for the management of neuropathic pain. It helps rejuvenate and protect damaged nerve cells by producing myelin.

Yes, some young people who have taken Duvanta NP 40 Tablet have experienced suicidal thoughts, so people of that age group should be monitored closely while on Duvanta NP 40 Tablet . Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.

Yes, Duvanta NP 40 Tablet may rarely cause weight gain, but is not experienced by everyone. Follow the regular diet and exercise to maintain a healthy weight.

Dry mouth could be a side-effect of Duvanta NP 40 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not discontinue Duvanta NP 40 Tablet without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Duvanta NP 40 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Duvanta NP 40 Tablet ; your doctor will reduce the dose gradually.

Duvanta NP 40 Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.

Duvanta NP 40 Tablet may cause sexual disturbances such as decreased sex drive and problems with erection. Consult your doctor if you have any concerns regarding this.

Duvanta NP 40 Tablet should be taken only for the duration prescribed by the doctor. As neuropathic pain is a chronic condition, it might be safe to take Duvanta NP 40 Tablet for a long time if prescribed by the doctor. Talk to the doctor if you have any concerns.

It might take a few weeks for you to feel better after starting Duvanta NP 40 Tablet . To treat your condition effectively, keep taking Duvanta NP 40 Tablet for as long as it has been prescribed by the doctor.

Duvanta NP 40 Tablet is indicated in the treatment of neuropathic pain. Consult the doctor if you have depression and/or diabetes; the doctor will prescribe the appropriate medicine based on your condition.

Duvanta NP 40 Tablet may cause side effects like nausea, constipation, headache, drowsiness, dry mouth, insomnia (difficulty in sleeping), erectile dysfunction, and low sexual desire. Most of these side effects of Duvanta NP 40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DUV0004

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.8650.pdf
  2. https://www.npra.gov.my/images/reg-and-noti/PI/non-poison/Mecobalamin-Template-oral-Website.pdf
  3. https://www.drugs.com/duloxetine.html

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