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  3. Eflora Cream 15 gm

Eflora Cream 15 gm, Pack of 1 CREAM
Eflora Cream 15 gm, Pack of 1 CREAM
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Eflora Cream is used to treat unwanted growth of facial hair (facial hirsutism) in women. It is also used to treat African sleeping sickness, a disease caused by protozoa. It contains Eflornithine which works by blocking a natural substance that stimulates hair growth. In some cases, this medicine may cause side effects such as acne, burning sensation, itching, scaling, skin dryness, mild tingling sensation or tenderness at the application site.
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Composition :

EFLORNITHINE-13.9%W/W

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Eflora Cream

Eflora Cream belongs to a class of drugs called hair growth retardant used to treat unwanted excess growth of facial hair (facial hirsutism) in women. It is also used to treat African sleeping sickness, a disease caused by protozoa. Facial hirsutism is a condition in women that results in develops excessive hair growth on the face. Unwanted facial hair in women can be a cosmetic problem and may produce emotional distress and mental trauma.

Eflora Cream contains Eflornithine is an ornithine decarboxylase (ODC) inhibitor that works by blocking a natural substance ornithine decarboxylase (an enzyme in the body involved in the production of hair) that stimulates hair growth and is located in the hair follicle (the sac where each hair grows). Eflora Cream is also used to treat African sleeping sickness (a disease caused by parasite infection).

Use Eflora Cream as prescribed by your doctor. You are advised to use Eflora Cream for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience acne, burning sensation, itching, scaling, skin dryness, mild tingling sensation or tenderness at the application site, bleeding, sore throat, and fever. Most of these side effects of Eflora Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Eflora Cream or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Eflora Cream. Eflora Cream is not recommended for use in children below 12 years.  Inform your doctor if you have acne, anemia, or other blood problems, hearing loss and kidney or liver problems before using Eflora Cream. Do not apply Eflora Cream on sunburned, cuts, grazes and broken skin. Besides this let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Eflora Cream.  

Uses of Eflora Cream

Treatment of Facial hirsutism (unwanted facial hair in women), African sleeping sickness.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Take a small amount of Eflora Cream on the fingertip and apply it as a thin layer on the clean and dry affected area as advised by your doctor.• Do not apply for at least 5 minutes after hair removal (such as plucking, shaving). Do not wash the treated area for at least 4 hours.

Medicinal Benefits

Eflora Cream contains Eflornithine used to slow the growth of unwanted hair on the face in women, usually around the lips or under the chin. It works by blocking a natural substance ornithine decarboxylase (an enzyme in the body involved in the production of hair) that stimulates hair growth and is located in the hair follicle (the sac where each hair grows). Eflora Cream slows hair growth and may also make the hair finer and lighter. It does not remove hair or cause the hair to fall out. Besides this, Eflora Cream also used to treat African sleeping sickness, a disease caused by protozoa (Trypanosoma brucei).

How Eflora Cream Works

Eflora Cream contains Eflornithine is an ornithine decarboxylase (ODC) inhibitor that works by blocking a natural substance ornithine decarboxylase (an enzyme in the body involved in the production of hair) that stimulates hair growth and is located in the hair follicle (the sac where each hair grows). Eflora Cream is also used to treat African sleeping sickness (a disease caused by parasite infection).

Storage

Keep Eflora Cream out of the sight and reach of children.
Side effects of Eflora Cream 15 gm
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
  • Stop taking the medication you suspect for causing a burning sensation and talk to your doctor about other treatment options.
  • Use creams or ointments with corticosteroids on the affected area to help reduce swelling and itching.
  • Stay out of the sun and avoid extreme temperatures, as they can make the burning sensation worse.
  • Applying a cool compress to the area can help soothe it temporarily.
  • Drink lots of fluids or water to keep your skin hydrated.
  • Avoid harsh soaps, strong chemicals, hot water, and tight clothing that can irritate your skin.
  • Eat foods that are high in antioxidants and omega-3 to help keep your skin healthy.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.

What if I have taken an overdose of Eflora Cream

Though overdose is unlikely due to low systemic absorption, it is advised to avoid exceeding the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not use Eflora Cream if you are allergic to Eflora Cream or inactive ingredients (such as methylparaben), which can cause allergic reactions or other problems. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before using Eflora Cream. Please inform your doctor if you are using any prescription and non-prescription medications you are taking, including vitamins, before starting Eflora Cream. Do not apply Eflora Cream on the irritated and sunburned skin, cuts graze, and broken skin. Let your doctor know if you have had acne, liver, or kidney problems before using Eflora Cream. Before you apply cosmetics or sunscreen wait until Eflora Cream dries completely. Do not wash the treatment areas for at least 4 hours after using Eflora Cream. Before using Eflora Cream you should wait for 5 minutes after using your current method of hair removal. This medicine may take 4-6 weeks or longer before you see the full benefit. Do not stop applying Eflora Cream without informing your doctor. Stopping the use of this medicine will resume hair growth. If you do not see any improvement after using it for 4 months contact your doctor. Eflora Cream is not a depilatory (hair remover) cream, so you may need to continue with your hair removal methods like shaving or plucking.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and sleep peacefully. 
  • A mixture of gram flour, turmeric, and curd marginally reduced hair growth. Apply this mixture on the face and rinse it after it dries.
  • Maintain a healthy weight. If you are overweight, your body may make fewer male hormones.
  • Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Remove the make-up completely before going to bed.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Eflora Cream Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of Eflora Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Eflora Cream.

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Pregnancy

Caution

Eflora Cream is a pregnancy category C drug. Please consult a doctor if you are pregnant. Eflora Cream is prescribed to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Eflora Cream is excreted in human milk. Therefore, Eflora Cream is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Eflora Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Eflora Cream.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or renal impairment. Your doctor will weigh the benefits and potential risks before prescribing Eflora Cream.

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Children

Unsafe

Eflora Cream is not recommended for children below 12 years of age, as the safety and effectiveness were not established.

Have a query?

FAQs

Eflora Cream is used to treat unwanted excess growth of facial hair (facial hirsutism) in women. It is also used to treat African sleeping sickness, a disease caused by protozoa.

Eflora Cream contains Eflornithine that stops the activity of an enzyme called ornithine decarboxylase that involved in the production of hair on the face. It also used to treat sleeping sickness (a disease caused by a protozoan infection in Africa).

Yes, Eflora Cream may cause skin irritation, redness or peeling in some people. However, if the irritation persists or worsens, stop using Eflora Cream and consult a doctor.

Eflora Cream usually improves your skin condition in 4 to 8 weeks or longer of treatment. If you notice no improvement after a 5-6 month of treatment, please reach out to your doctor.

Eflora Cream is for topical (for skin) use only. Do not apply Eflora Cream on open wounds or on sunburned, windburned, dry, chapped or irritated skin, mucous membranes, lesions, or large areas of skin. If the medicine gets into your eyes, nose or mouth, rinse with cold water. This medicine is for use only on the face and chin. Do not apply to other areas of the body.

No, it is not advised to stop using Eflora Cream even after your symptoms are relieved. You should complete the full course of treatment. You might see improvement in your symptoms, but hair growth may return to pretreatment levels after you stop using eflornithine topical. Consult your doctor for further advice.

No, Eflora Cream is not recommended for use in children as the safety and effectiveness were not established.

Eflora Cream does not remove hair or cause hair loss. However, it should not be used on other body parts or the scalp as Eflora Cream is used to treat unwanted growth of facial hair (facial hirsutism) in women.

Eflora Cream should be used for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Clean and dry the affected areas and apply Eflora Cream as a thin layer. Gently massage it into the skin with your fingers. Wash your hands before and after applying the medicine.

Eflora Cream may cause a mild stinging sensation. However, it is advised to consult the doctor if the stinging sensation persists or worsens.

Eflora Cream may cause side effects like acne, burning sensation, itching, scaling, skin dryness, mild tingling sensation or tenderness at the application site, bleeding, sore throat, and fever. Most of these side effects of Eflora Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - EFL0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.drugs.com/mtm/eflornithine-topical.html
  2. https://www.medicines.org.uk/emc/files/pil.6398.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2000/21145lbl.pdf

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