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compositionComposition:PANTOPRAZOLE-40MG
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Prescription Medicine
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Eiref-40 Tablet is used to treat gastroesophageal reflux disease (GERD), stomach ulcer, Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour), duodenal ulcer, gastric ulcer and Crohn's Disease-associated Ulcers. It contains Pantoprazole, which reduces the amount of acid your stomach makes. It prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn. It may cause common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Composition :

PANTOPRAZOLE-40MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Eiref-40 Tablet

Eiref-40 Tablet belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Eiref-40 Tablet helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus prevents the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Eiref-40 Tablet will get these side effects. Eiref-40 Tablet may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, dizziness, and joint pain. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Take Eiref-40 Tablet as advised. Your physician will decide the dosage based on your medical condition. You should take Eiref-40 Tablet 30 minutes before food. It is recommended not to exceed the recommended dose of Eiref-40 Tablet . Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Eiref-40 Tablet . Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Eiref-40 Tablet  or will have an endoscopy in the future. Prolonged intake of Eiref-40 Tablet may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis. Eiref-40 Tablet is not recommended for children below 5 years of age. Consult the doctor if you are pregnant or breastfeeding.

Uses of Eiref-40 Tablet

Eiref-40 Tablet is used to treat peptic ulcers, heartburn, and hyperacidity. The following are the specific applications of Eiref-40 Tablet :

  • Gastric reflux disease (GERD): Eiref-40 Tablet is frequently used to treat GERD by decreasing the production of stomach acid, which lessens the symptoms of acid reflux and heartburn.
  • Erosive Esophagitis: This medication efficiently promotes healing and symptom relief for this ailment, which is brought on by inflammation and damage to the oesophagus as a result of acid reflux.
  • Peptic Ulcers: By lowering stomach acid, Eiref-40 Tablet can be used to treat peptic ulcers and promote the healing of the affected areas.
  • Zollinger-Ellison Syndrome: This uncommon ailment results in an overabundance of stomach acid. Eiref-40 Tablet considerably lowers acid secretion, which aids with symptom management.

Key Benefits

  • Eiref-40 Tablet is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers. 
  • Eiref-40 Tablet works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Eiref-40 Tablet helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.
Side effects of Eiref-40 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
  • Avoid smoking and drinking alcohol as it can worsen your condition.
  • Drink warm fluids such as warm water with honey, broth or herbal tea to soothe sore throat.
  • Gargle with warm salt water to decrease inflammation.
  • Suck on hard candies or lozenges to increase the production of saliva and soothe your throat.
  • Avoid smoking, spicy foods, and extremely hot fluids.
  • Rest your voice and get enough sleep.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Eiref-40 Tablet should be taken 30-60 minutes before a meal to enhance absorption and effectiveness.
  • It is usually taken once daily in the morning or as advised by your doctor. If prescribed twice daily, take the second dose before dinner.
  • Swallow Eiref-40 Tablet as a whole with a glass of water.
  • Do not crush, chew, open, or break it.

How Eiref-40 Tablet Works

Eiref-40 Tablet contains pantoprazole as an active ingredient. It helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase) that is located in the cells of the stomach wall and is responsible for releasing gastric acid, which can damage tissues in the food pipe, stomach, and duodenum. Eiref-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.
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Alcohol

Unsafe

Drinking alcohol with Eiref-40 Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Eiref-40 Tablet .

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Pregnancy

Consult your doctor

Eiref-40 Tablet is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Consult your doctor

Eiref-40 Tablet is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Driving

Caution

In some cases, Eiref-40 Tablet may cause dizziness, sleepiness, or blur vision. If you observe these symptoms, do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Eiref-40 Tablet should be taken with caution if you have liver problems.

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Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking Eiref-40 Tablet .

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Children

Caution

Eiref-40 Tablet is not be prescribed for children under 5 years of age. It is generally prescribed from 5-16 years of children for the treatment of gastroesophageal reflux disease (GERD).

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Heart

Safe if prescribed

Eiref-40 Tablet can generally be used even if you have heart problems, but only under your doctor’s guidance. Consult your doctor if you have any concerns regarding it.

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Geriatrics

Caution

Eiref-40 Tablet can be taken by geriatric patients, but with caution and medical supervision.

What if I have taken an overdose of Eiref-40 Tablet

Do not take more than the prescribed dose of Eiref-40 Tablet as it may cause gastic irritation, trouble breathing or passing out. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid consuming foods or drinks that trigger acid reflux or heartburn, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat foods, and spicy foods.
  • Before going to sleep, raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backing up into your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing the backflow of the stomach acid into the food pipe.
  • Include high-fibre-containing foods, such as berries, cherries, leafy green veggies (like kale and spinach), and black pepper in your meal. These foods are rich in antioxidants, calcium, and vitamin B12, which can help mitigate the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H. pylori infection.
  • Avoid sitting for long periods, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

health query

Have a query?

How Soon It Starts Working

The time required for Eiref-40 Tablet to start to work: Eiref-40 Tablet ideally shows its action within an hour after administration. The time for which the effects of Eiref-40 Tablet last: The effect of Eiref-40 Tablet lasts for 24 hours.

What if you forget to take Eiref-40 Tablet

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid taking Eiref-40 Tablet if you are allergic to Eiref-40 Tablet or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1. 
  • Prolonged intake of Eiref-40 Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), vitamin B12, and magnesium deficiency. 
  • Eiref-40 Tablet may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications. Please inform your doctor if you are taking any of these medications. 
  • Intake of Eiref-40 Tablet may mask the symptoms of gastric cancer, so if you have any severe stomach pain or blood in stool, immediately consult the doctor.
  • This medicine is not recommended for use in children below 5 years of age. 
  • Although Eiref-40 Tablet is safe for use during pregnancy or breastfeeding, inform your doctor if you are pregnant or breastfeeding before starting treatment with Eiref-40 Tablet . 
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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Drug-Drug Interaction: Eiref-40 Tablet may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interaction: Eiref-40 Tablet interacts with St John's wort plant that is used as an antidepressant. This plant may affect the working of Eiref-40 Tablet . So avoid its intake with Eiref-40 Tablet .

Drug-Disease Interaction: Eiref-40 Tablet should not be given to patients with Clostridium difficile-induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), and low magnesium (hypomagnesemia).

PantoprazoleRilpivirine
Critical
PantoprazoleGefitinib
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Eiref-40 Tablet:
Co-administration of Rilpivirine is taken with Eiref-40 Tablet, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Eiref-40 Tablet with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazoleGefitinib
Severe
How does the drug interact with Eiref-40 Tablet:
Taking Gefitinib with Eiref-40 Tablet reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Eiref-40 Tablet with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Eiref-40 Tablet to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
PantoprazoleMethotrexate
Severe
How does the drug interact with Eiref-40 Tablet:
Co-administration of Methotrexate with Eiref-40 Tablet can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Eiref-40 Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleDacomitinib
Severe
How does the drug interact with Eiref-40 Tablet:
Taking Eiref-40 Tablet can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Eiref-40 Tablet with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazolePazopanib
Severe
How does the drug interact with Eiref-40 Tablet:
Taking Eiref-40 Tablet with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Eiref-40 Tablet and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleErlotinib
Severe
How does the drug interact with Eiref-40 Tablet:
Taking Erlotinib with Eiref-40 Tablet may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Eiref-40 Tablet with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Eiref-40 Tablet:
Taking Nelfinavir with Eiref-40 Tablet may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Eiref-40 Tablet with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleAtazanavir
Severe
How does the drug interact with Eiref-40 Tablet:
Co-administration of Eiref-40 Tablet reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Eiref-40 Tablet with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleDasatinib
Severe
How does the drug interact with Eiref-40 Tablet:
Taking Dasatinib with Eiref-40 Tablet may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Eiref-40 Tablet with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Eiref-40 Tablet is used to treat Hyperacidity, Heartburn, and Peptic ulcer.
Eiref-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.
No. Gas and acidity are two different common discomforts. Acidity is caused when the improper functioning of the valve (sphincter) is located at the junction of the stomach and the food pipe. As a result, stomach acid backs up and enters the upper part of the oesophagus, causing heartburn. On the other hand, gas is a byproduct of digestion, eliminating gases like carbon dioxide, hydrogen, nitrogen, and methane from the body.
Yes. Eiref-40 Tablet can alter specific medical tests, such as neuroendocrine tumour (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such tests, contact your doctor.
Prolonged intake of Eiref-40 Tablet may weaken your bone and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.
No. Eiref-40 Tablet prevents the excessive production of stomach acid, which can cause acid reflux and heartburn. If blood is present in your stool or mucus, contact your doctor immediately.
Prolonged intake of Eiref-40 Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin-enhancing medications to cope with long-term side effects.
No. Eiref-40 Tablet is not prescribed for stomach cancer. Do not take Eiref-40 Tablet until your doctor has prescribed it to you. Eiref-40 Tablet is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.
You should start to feel better in 2-3 days of starting Eiref-40 Tablet . However, it might take up to 4 weeks for Eiref-40 Tablet to work properly. Consult a doctor if you don't feel better or if your condition doesn't improve.
A single dose of Eiref-40 Tablet may not be sufficient. To treat your condition properly, take Eiref-40 Tablet in the dose and for the duration prescribed by your doctor.
Yes, it is safe to take Eiref-40 Tablet if your doctor prescribes it. It is a well-tolerated medicine.
Eiref-40 Tablet is usually prescribed for a short term. However, in some cases, it may be indicated in the long-term management of reflux oesophagitis. If you take Eiref-40 Tablet on a long-term basis (longer than 1 year), your doctor will advise regular monitoring.
It is best to take Eiref-40 Tablet 30 minutes to one hour before a meal.
Eiref-40 Tablet should not be discontinued without a doctor’s consultation. To treat your condition effectively, take Eiref-40 Tablet for as long as it has been prescribed. Talk to the doctor if you have any concerns.
Eiref-40 Tablet may cause weight changes as a side effect. Consult the doctor if you notice any weight changes that bother you.
Avoid alcohol consumption as it might make your stomach produce more acid than usual. This can irritate the stomach lining and make your symptoms worse.
Antacids can be taken with Eiref-40 Tablet if prescribed by the doctor. However, maintain a 2-hour gap between Eiref-40 Tablet and antacid medicines.
Eat smaller and more frequent meals. Avoid foods that trigger acidity, such as fatty and fried foods, spicy foods, carbonated drinks, and alcohol. Include non-citrus fruits, vegetables, lean meat, oatmeal, whole-grain bread, and rice in your diet. Do not lie down immediately after eating, and avoid vigorous exercise for at least a couple of hours afterwards.
Yes, it is safe to take painkillers along with Eiref-40 Tablet if advised by the doctor. To prevent stomach upset, painkillers can be taken with or just after a meal.
Eiref-40 Tablet should be swallowed as a whole with water; do not crush, break or chew it. Eiref-40 Tablet should be taken 30-60 minutes before meal.
Take the missed dose as soon as you remember, unless it is time for the scheduled dose. Do not take a double dose to make up for the forgotten dose. Take your next regular dose at the usual time.
In some people, Eiref-40 Tablet may cause side effects such as headaches, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, contact your doctor.

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Reference

  1. Drugs.com Clinical Review Team. Pantoprazole Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Pantoprazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Pantoprazole Granules Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Pantoprazole Pantoprazole. 2000. [Accessed on 28 Mar. 2019]Check here
  6. Drugs and Lactation Database (LactMed®) [Internet]. 2006. [Accessed on 25 Jul. 2023]Check here
  7. Pantoprazole sodium. 2026. [Accessed on 27 Jan. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - EIR0007

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