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compositionComposition:SODIUM VALPROATE-100MG
prescriptionPrescription Medicine
Encorate 100 mg Injection 5 ml
Encorate 100 mg Injection 5 ml
Encorate 100 mg Injection 5 ml

Encorate 100 mg Injection 5 ml is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It helps reduce mood swings and improve impulsive behaviour.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

SODIUM VALPROATE-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Encorate 100 mg Injection 5 ml is used to treat epilepsy/seizures/fits. Additionally, Encorate 100 mg Injection 5 ml is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain.

Encorate 100 mg Injection 5 ml contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. This helps in controlling seizures.

This medicine will be administered by your doctor. Encorate 100 mg Injection 5 ml may cause side effects, such as sleepiness, weakness, dizziness, nausea, and headache. Talk to your doctor if you experience these side effects persistently.

Please do not stop taking Encorate 100 mg Injection 5 ml without consulting your doctor to avoid worsening of seizures. Do not take Encorate 100 mg Injection 5 ml if you are pregnant, as it could cause serious congenital disabilities. Consult your doctor before taking Encorate 100 mg Injection 5 ml if you are breastfeeding.

Uses of Encorate 100 mg Injection 5 ml

Encorate 100 mg Injection 5 ml is used to manage neurological and psychiatric conditions. The detailed uses of Encorate 100 mg Injection 5 ml include:

  • Treatment of epilepsy/seizures: Encorate 100 mg Injection 5 ml helps control various types of seizures, including generalised, focal, and absence seizures, by stabilising electrical activity in the brain.
  • Management of bipolar disorder: Encorate 100 mg Injection 5 ml is effective in treating manic episodes associated with bipolar disorder and helps maintain mood stability.
  • Migraine: Encorate 100 mg Injection 5 ml is used to help prevent migraine headaches. It reduces the frequency and severity of migraine attacks by stabilising nerve activity in the brain.

Key Benefits

When used as prescribed, Encorate 100 mg Injection 5 ml may offer the following benefits

For Epilepsy:

  • Regulates a variety of seizure types, such as absence, focal, and generalised seizures.
  • Reduces the frequency and intensity of seizures by stabilising aberrant electrical activity in the brain.
  • Beneficial either alone or in conjunction with other antiepileptic medications.

For Bipolar disorder:

  • Stabilises mood, which aids in the management of acute manic episodes.
  • Reduce mood fluctuations and stop manic relapses.
  • Helpful for patients who don't react well to lithium.
  • Reduces impulsive behaviour, agitation, and irritation.

For Migraine:

  • Helps prevent migraine attacks when taken regularly.
  • Reduces the frequency of migraine episodes.
  • Decreases the severity and duration of headaches.
  • Stabilises overactive nerve signals involved in migraines.
  • Improves the quality of life in people with recurrent migraines.
Side effects of Encorate 100 mg Injection 5 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Encorate 100 mg Injection 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.
Encorate 100 mg Injection 5 ml contains 'Sodium valproate' as an active ingredient. • For seizures, it decreases the excessive and abnormal nerve activity in the brain. Thereby, helps in controlling seizures. • For Bipolar disorder, it increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder • For Migraine, it controls abnormal nerve signals and prevents the chain of events that trigger migraine attacks, helping reduce the frequency and severity of migraines..
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Encorate 100 mg Injection 5 ml as it may cause increased dizziness and sleepiness.

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Pregnancy

Consult your doctor

Encorate 100 mg Injection 5 ml may cause serious congenital defects and decreased IQ. Therefore, Encorate 100 mg Injection 5 ml should be given to pregnant women with epilepsy only if other medicines have failed to control their symptoms or are unacceptable.

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Breast Feeding

Consult your doctor

Encorate 100 mg Injection 5 ml may pass into breastmilk. Consult your doctor before taking Encorate 100 mg Injection 5 ml if you are breastfeeding.

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Driving

Unsafe

Encorate 100 mg Injection 5 ml causes dizziness, sleepiness and tiredness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Unsafe

Encorate 100 mg Injection 5 ml may cause hepatotoxicity (liver damage). Therefore, it is not recommended for people with hepatic dysfunction. Please inform your doctor if you have a liver impairment or liver problem.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Encorate 100 mg Injection 5 ml can be given to children above 2 years if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight. Encorate 100 mg Injection 5 ml should be used with extreme caution in children below 2 years as it might cause hepatotoxicity (liver damage).

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Heart

Caution

If you have any history of heart disease before taking Encorate 100 mg Injection 5 ml, please inform your doctor. Your doctor may adjust the dose based on your condition.

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Geriatrics

Caution

Encorate 100 mg Injection 5 ml should be used with caution in elderly patients. Please consult your doctor before use.

An overdose may cause side effects like diarrhoea, nausea, vomiting, and stomach pain. However, it is administered by a health care professional in a hospital. Hence, the chances of overdose are less. Your doctor may take necessary measures if an overdose is suspected.

Diet & Lifestyle Advise

Healthy eating habits:

  • To preserve general health, eat a diet rich in fruits, vegetables, whole grains, and lean meats.
  • Eat fewer greasy and fried foods to ease the liver's burden.
  • To lessen upset stomach, drink enough water and eat at regular times.

Lifestyle changes:

  • Steer clear of recreational drugs and alcohol, as they can exacerbate seizures and negative effects.
  • Sleep deprivation can cause mood swings or seizures, so make sure you get enough sleep and control your stress.

Stress management:

  • To lower stress, engage in relaxation methods like yoga, meditation, or deep breathing.
  • Walking is a gentle kind of exercise that might enhance mental health.
  • When you're feeling overwhelmed, ask friends, family, or a counsellor for emotional assistance.

Have a query?

Drug Warnings

  • Do not take Encorate 100 mg Injection 5 ml if you are allergic to any of its contents.
  • Inform your doctor if you have liver problems, porphyria (blood disorder), urine-related problems (like urea cycle disorder), diabetes, an immune system disorder or kidney problems.
  • Consult your doctor immediately if you experience suicidal tendencies while taking Encorate 100 mg Injection 5 ml.
  • Contact your doctor if your child gets her first period during the treatment with Encorate 100 mg Injection 5 ml.
  • Do not take Encorate 100 mg Injection 5 ml if you are pregnant unless prescribed by the doctor, as it is a pregnancy category C medicine and can cause serious congenital disabilities.
  • Consult your doctor before taking Encorate 100 mg Injection 5 ml if you are breastfeeding.
  • Encorate 100 mg Injection 5 ml may cause drowsiness and dizziness, so drive only if you are alert.
  • Avoid consuming alcohol along with Encorate 100 mg Injection 5 ml as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateErtapenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Encorate 100 mg Injection 5 ml:
Combining Sodium phenylbutyrate and Encorate 100 mg Injection 5 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Encorate 100 mg Injection 5 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
The combined use of Ertapenem and Encorate 100 mg Injection 5 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Encorate 100 mg Injection 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Ketamine and Encorate 100 mg Injection 5 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Encorate 100 mg Injection 5 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Lithium with Encorate 100 mg Injection 5 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Encorate 100 mg Injection 5 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Using buprenorphine together with Encorate 100 mg Injection 5 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Encorate 100 mg Injection 5 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Teriflunomide and Encorate 100 mg Injection 5 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Encorate 100 mg Injection 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Leflunomide and Encorate 100 mg Injection 5 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Encorate 100 mg Injection 5 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Encorate 100 mg Injection 5 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Encorate 100 mg Injection 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Meropenam and Encorate 100 mg Injection 5 ml together can reduce the effect of Encorate 100 mg Injection 5 ml.

How to manage the interaction:
Co-administration of Meropenam and Encorate 100 mg Injection 5 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Encorate 100 mg Injection 5 ml:
Co-administration of Vorinostat with Encorate 100 mg Injection 5 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Encorate 100 mg Injection 5 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Encorate 100 mg Injection 5 ml belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder.

Encorate 100 mg Injection 5 ml decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Encorate 100 mg Injection 5 ml is used to treat bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Encorate 100 mg Injection 5 ml may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Encorate 100 mg Injection 5 ml may cause hepatotoxicity (liver damage). Consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). Serum liver tests before starting Encorate 100 mg Injection 5 ml and at regular intervals for at least six months are advised.

Encorate 100 mg Injection 5 ml should not be administered to women of childbearing age unless it is essential to manage their condition. Women of child-bearing age must use effective contraception whilst on treatment with Encorate 100 mg Injection 5 ml.

Encorate 100 mg Injection 5 ml may cause side effects, such as sleepiness, weakness, dizziness, nausea, and headache. Talk to your doctor if you experience these side effects persistently.

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

  • Santoshini Reddy G

    M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

  • Veda Maddala

    M Pharmacy

Last Updated

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