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compositionComposition:SODIUM VALPROATE-200MG
prescriptionPrescription Medicine
Encorate Oral Solution 200 ml
Encorate Oral Solution 200 ml

Encorate Oral Solution is used to treat epilepsy and helps control different types of seizures or fits. It reduces the frequency and severity of seizure episodes and supports long-term seizure management, improving overall quality of life. Additionally, Encorate Oral Solution is used in the treatment of bipolar disorder, where it helps stabilise mood, reduce episodes of mania, and control mood swings. In some patients, it may also be prescribed to help prevent recurrent migraine headaches.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

SODIUM VALPROATE-200MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Encorate Oral Solution

Encorate Oral Solution is used to treat epilepsy/seizures/fits. Additionally, Encorate Oral Solution is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain.

Encorate Oral Solution contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. This helps in controlling seizures.

Encorate Oral Solution may cause common side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Please do not stop taking Encorate Oral Solution without consulting your doctor to avoid worsening of seizures. Do not take Encorate Oral Solution if you are pregnant, as it could cause serious congenital disabilities. Consult your doctor before taking Encorate Oral Solution if you are breastfeeding.

Uses of Encorate Oral Solution

Encorate Oral Solution is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Encorate Oral Solution are as follows:

  • Seizure Management: Encorate Oral Solution is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.
  • Bipolar Disorder Treatment: Encorate Oral Solution can be used in the treatment of bipolar disorder, aiding in mood stabilisation and reducing the frequency of mood swings.
  • Migraine: Encorate Oral Solution is used to help prevent migraine headaches. It reduces the frequency and severity of migraine attacks by stabilising nerve activity in the brain.

Health Queries

What medications are recommended for seizures?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Seizures are usually treated with anti-epileptic medications, and the choice depends on the type of seizures and your overall health. Commonly used medicines include Levetiracetam, Sodium Valproate, Carbamazepine, and Lamotrigine. These medicines help control seizures effectively when taken regularly, but they should only be started or adjusted under a doctor's guidance after proper diagnosis.

I may be experiencing absence seizures. What treatment or medications are recommended?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

If you may be experiencing absence seizures, it is important to first get a proper diagnosis, usually with tests like an EEG (electroencephalogram), which can confirm the type of seizure. Absence seizures are often well controlled with medication, and the choice of medicine depends on your age, overall health, and specific seizure pattern. Common medications include ethosuximide, valproate, or lamotrigine, but the exact drug and dose should be decided by a neurologist. It is crucial to take the prescribed medicine regularly, follow up with your doctor, and avoid stopping treatment abruptly, as this helps prevent further episodes. Additionally, keeping a seizure diary, noting triggers, and maintaining a safe environment are important parts of managing the condition.

I have hypertension and weakness, and I have experienced about three seizure episodes in the past six months. Could this indicate a seizure disorder?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Having about three seizure episodes in six months along with Hypertension may suggest a seizure disorder like Epilepsy, but this needs proper medical evaluation to confirm. Consult a doctor or neurologist, who may advise tests like an EEG and brain scan to find the cause. Early diagnosis and treatment can help control seizures effectively and reduce future risks.

I have migraine and am taking Encorate 200 mg twice daily. Is this safe for long-term use, or are there safer alternatives?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Encorate 200 is commonly used to prevent migraines and can be effective for long-term use when taken under regular medical supervision. However, it may cause side effects such as weight gain, sleepiness, hair thinning, or stomach upset, and in rare cases, it can affect the liver, so your doctor may advise periodic blood tests. Whether it is the best option for you depends on your response and any side effects. There are other preventive medicines available which your doctor may consider if needed. Do not stop or change the medicine on your own, as this can worsen migraines. Regular follow-up with your doctor will help ensure safe and effective long-term management.

Have a query?

Directions for Use

  • Encorate Oral Solution can be taken with food to prevent stomach upset or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Take the prescribed dose by mouth using the measuring cup, dosing syringe, or dropper.
  • Shake the bottle well before use.

Key Benefits

When used as prescribed, Encorate Oral Solution may offer the following benefits

For Epilepsy:

  • Regulates a variety of seizure types, such as absence, focal, and generalised seizures.
  • Reduces the frequency and intensity of seizures by stabilising aberrant electrical activity in the brain.
  • Beneficial either alone or in conjunction with other antiepileptic medications.
  • Both adults and children with epilepsy can benefit from it.

For Bipolar disorder:

  • Stabilises mood, which aids in the management of acute manic episodes.
  • Reduce mood fluctuations and stop manic relapses.
  • Helpful for patients who don't react well to lithium.
  • Reduces impulsive behaviour, agitation, and irritation.

For Migraine:

  • Helps prevent migraine attacks when taken regularly.
  • Reduces the frequency of migraine episodes. Decreases the severity and duration of headaches.
  • Stabilises overactive nerve signals involved in migraines.
  • Improves the quality of life in people with recurrent migraines.

How Encorate Oral Solution Works

Encorate Oral Solution contains 'Sodium valproate' as an active ingredient. • For seizures, it decreases the excessive and abnormal nerve activity in the brain. Thereby, helps in controlling seizures. • For Bipolar disorder, it increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. • For Migraine, it controls abnormal nerve signals and prevents the chain of events that trigger migraine attacks, helping reduce the frequency and severity of migraines.

Storage

Store in a cool and dry place away from sunlight
Side effects of Encorate Oral Solution 200 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Avoid tobacco products, as smoking can worsen gum problems.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Consult your dentist if gums bleed consistently.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of Encorate Oral Solution

Do not take more than the prescribed dose of Encorate Oral Solution as it may cause an overdose. The symptoms of overdose include headache, dizziness, confusion, memory loss, tiredness, feeling sick or being sick, blurred vision due to pupil of the eye becoming smaller, poor reflexes, weak or floppy muscles, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing, shortness of breath or chest pain. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Encorate Oral Solution if you are allergic to any of its contents.
  • Inform your doctor if you have liver problems, porphyria (blood disorder), urine-related problems (like urea cycle disorder), diabetes, an immune system disorder or kidney problems.
  • Consult your doctor immediately if you experience suicidal tendencies while taking Encorate Oral Solution .
  • Contact your doctor if your child gets her first period during the treatment with Encorate Oral Solution .
  • Do not take Encorate Oral Solution if you are pregnant unless prescribed by the doctor, as it is a pregnancy category C medicine and can cause serious congenital disabilities.
  • Consult your doctor before taking Encorate Oral Solution if you are breastfeeding.
  • Encorate Oral Solution may cause drowsiness and dizziness, so drive only if you are alert.
  • Avoid consuming alcohol along with Encorate Oral Solution as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateDoripenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Encorate Oral Solution 200 ml:
Combining Sodium phenylbutyrate and Encorate Oral Solution 200 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Encorate Oral Solution 200 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Encorate Oral Solution 200 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Encorate Oral Solution 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
The combined use of Ertapenem and Encorate Oral Solution 200 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Encorate Oral Solution 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Using buprenorphine together with Encorate Oral Solution 200 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Encorate Oral Solution 200 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Teriflunomide and Encorate Oral Solution 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Encorate Oral Solution 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Vorinostat with Encorate Oral Solution 200 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Encorate Oral Solution 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Ketamine and Encorate Oral Solution 200 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Encorate Oral Solution 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Leflunomide and Encorate Oral Solution 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Encorate Oral Solution 200 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Lithium with Encorate Oral Solution 200 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Encorate Oral Solution 200 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Encorate Oral Solution 200 ml:
Co-administration of Meropenam and Encorate Oral Solution 200 ml together can reduce the effect of Encorate Oral Solution 200 ml.

How to manage the interaction:
Co-administration of Meropenam and Encorate Oral Solution 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy eating habits:

  • To preserve general health, eat a diet rich in fruits, vegetables, whole grains, and lean meats.
  • Eat fewer greasy and fried foods to ease the liver's burden.
  • To lessen upset stomach, drink enough water and eat at regular times.

Lifestyle changes:

  • Steer clear of recreational drugs and alcohol, as they can exacerbate seizures and negative effects.
  • Sleep deprivation can cause mood swings or seizures, so make sure you get enough sleep and control your stress.
  • Attend routine blood testing and follow-ups to keep an eye on drug levels and liver function.

Stress management:

  • To lower stress, engage in relaxation methods like yoga, meditation, or deep breathing.
  • Walking is a gentle kind of exercise that might enhance mental health.
  • When you're feeling overwhelmed, ask friends, family, or a counsellor for emotional assistance.

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Encorate Oral Solution as it may cause increased dizziness and sleepiness.

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Pregnancy

Unsafe

Encorate Oral Solution belongs to pregnancy category D. Avoid taking Encorate Oral Solution if you are pregnant, as it could lead to serious birth defects.

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Breast Feeding

Consult your doctor

Encorate Oral Solution may pass into breastmilk. Consult your doctor before taking Encorate Oral Solution if you are breastfeeding.

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Driving

Unsafe

Encorate Oral Solution causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Encorate Oral Solution should not be used if you have liver disease or severe hepatitis. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Encorate Oral Solution can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

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Heart

Caution

If you have heart problems, please inform your doctor before taking Encorate Oral Solution , as it may cause fluid retention, interact with cardiac medications, and affect blood pressure regulation.

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Geriatrics

Caution

Encorate Oral Solution should be used with caution in elderly patients and only when prescribed by a doctor. Dose adjustment and careful monitoring of side effects are necessary in elderly patients.

FAQs

Encorate Oral Solution is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).

Encorate Oral Solution decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messengers and prevents overactivity of the brain, thereby controlling seizure episodes.

Encorate Oral Solution limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Do not discontinue Encorate Oral Solution without consulting your doctor. To treat your condition effectually, continue taking Encorate Oral Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Encorate Oral Solution ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Encorate Oral Solution works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Encorate Oral Solution may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Encorate Oral Solution may cause side effects like stomach pain, nausea, vomiting, diarrhoea, and changes in weight/appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Yes, Encorate Oral Solution causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

Encorate Oral Solution may change levels of liver enzymes, blood clotting factors, salts or sugars shown up on blood and urine tests. Hence, if you are undergoing any tests, inform the doctor that you are taking Encorate Oral Solution .

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - ENC0118

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Author Details

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Apr 3, 2026 | 11:37 AM IST

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