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  3. Endobest 2 Tab 10'S

Endobest 2 Tab 10'S, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Endobest 2 Tab is used to treat endometriosis. It contains Dienogest which suppresses the production of a hormone (oestradiol) that causes excess growth in the endometrium. In some cases, this medicine may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

DIENOGEST-2MG

Manufacturer/Marketer :

Zerico Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Endobest 2 Tab

Endobest 2 Tab is used for the management of painful symptoms of endometriosis. Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus. Endometriosis generally involves ovaries, pelvis lining, and fallopian tubes.
 
Endobest 2 Tab contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Endobest 2 Tab helps in treating pelvic pain associated with endometriosis.
 
You are advised to take Endobest 2 Tab as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Endobest 2 Tab may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid taking Endobest 2 Tab if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking Endobest 2 Tab . Endobest 2 Tab should not be given to children who have not had their first period. Endobest 2 Tab may cause dizziness, so drive with caution. Avoid or limit alcohol consumption, as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Endobest 2 Tab

Treatment of Endometriosis

Directions for Use

• Endobest 2 Tab can be taken with or without food as prescribed by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Endobest 2 Tab as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Endobest 2 Tab belongs to a group of medicines called progestin indicated for the management of endometriosis. Endobest 2 Tab suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, Endobest 2 Tab helps in treating pelvic pain associated with endometriosis. Endobest 2 Tab may also be used in menopausal hormonal therapy and heavy periods.

How Endobest 2 Tab Works

Endobest 2 Tab contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Endobest 2 Tab helps in treating pelvic pain associated with endometriosis.

Storage

Keep Endobest 2 Tab out of reach and sight of children.
Side effects of Endobest 2 Tab
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
  • Eat fiber-rich foods, fruits, and vegetables.
  • Monitor calorie intake and limit external food sources.
  • Weigh yourself weekly to track progress.
  • Enjoy balanced meals and indulge in treats moderately.
  • Prioritize sleep, exercise, and stress-reducing techniques.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Your doctor might suggest giving it some time to see if your sex drive improves after stopping the medication, adjusting the dose, or switching to another medication.
  • Engaging in regular aerobic exercise and strength training can enhance your stamina, improve your mood, and increase your sex drive.
  • Reduce stress by taking a vacation to relax or by practicing yoga.
  • Avoid consuming too much alcohol and smoking.
  • Maintain a healthy weight to support overall health.
  • Consult a sex therapist or counsellor skilled in addressing sexual concerns to help manage your low sex drive.

What if I have taken an overdose of Endobest 2 Tab

Take Endobest 2 Tab only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Endobest 2 Tab if you are allergic to any of its components; if you have a blood clot in the lungs, heart, brain, blood vessels of legs or any part of the body, if you have/had diabetes mellitus with damaged blood vessel, severe liver damage, unexplained vaginal bleeding, and benign or malignant tumour. Talk to your doctor if you have diabetes, high blood pressure, depression, are overweight, have chloasma (yellowish-brown pigmentation on the skin), had an ectopic pregnancy (embryo develops outside the womb), or if you or anyone in your immediate family has had blood clots in lungs/legs, or heart attack, high cholesterol or stroke. Avoid taking Endobest 2 Tab if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking Endobest 2 Tab . Endobest 2 Tab should not be given to children who have not had their first period. Endobest 2 Tab may cause dizziness, so drive with caution.

Drug-Drug Interactions

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DienogestEfavirenz
Critical
DienogestMycophenolic acid
Severe

Drug-Drug Interactions

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DienogestEfavirenz
Critical
How does the drug interact with Endobest 2 Tab:
When Efavirenz is taken with Endobest 2 Tab, it can lower the metabolism of Endobest 2 Tab and increase the risk or severity of side effects.

How to manage the interaction:
Taking Efavirenz with Endobest 2 Tab can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
DienogestMycophenolic acid
Severe
How does the drug interact with Endobest 2 Tab:
Co-administration of Endobest 2 Tab with Mycophenolic acid may decrease the levels and action of Endobest 2 Tab.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Endobest 2 Tab, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
DienogestPrimidone
Severe
How does the drug interact with Endobest 2 Tab:
Taking Endobest 2 Tab with Primidone may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between primidone and Endobest 2 Tab, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DienogestDantrolene
Severe
How does the drug interact with Endobest 2 Tab:
Co-administration of Dantrolene with Endobest 2 Tab can cause serious side effects that may affect your liver.

How to manage the interaction:
Taking Endobest 2 Tab with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
DienogestBosentan
Severe
How does the drug interact with Endobest 2 Tab:
Co-administration of Endobest 2 Tab with Bosentan may decrease the effectiveness of Endobest 2 Tab.

How to manage the interaction:
Although there is a possible interaction, Endobest 2 Tab can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DienogestFosphenytoin
Severe
How does the drug interact with Endobest 2 Tab:
When Endobest 2 Tab is taken with Fosphenytoin, it can increase the risk of severe bleeding.

How to manage the interaction:
Although taking Endobest 2 Tab and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DienogestCarbamazepine
Severe
How does the drug interact with Endobest 2 Tab:
Taking carbamazepine with Endobest 2 Tab may increase the effect of carbamazepine.

How to manage the interaction:
Although there is a possible interaction, Endobest 2 Tab can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
DienogestPhenytoin
Severe
How does the drug interact with Endobest 2 Tab:
Taking Phenytoin with Endobest 2 Tab may reduce the blood levels and effects of Endobest 2 Tab.

How to manage the interaction:
Although taking Phenytoin and Endobest 2 Tab together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Endobest 2 Tab as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Endobest 2 Tab with Grapefruit and Grapefruit juice may increase the side effects of Endobest 2 Tab. Consuming Grapefruit and grapefruit juice should be avoided while taking Endobest 2 Tab.

Diet & Lifestyle Advise

  • Include diet-fibrous foods, iron-rich foods, foods rich in essential fatty acids, and anti-oxidant rich food.

  • Maintain a healthy diet and exercise regularly.

  • Practice meditation and yoga. Acupuncture and massages can also be helpful.

  • Avoid or limit caffeine intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

Endobest 2 Tab Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is unknown if Endobest 2 Tab interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Endobest 2 Tab is not recommended during pregnancy. Please consult your doctor if you have any concerns regarding this. Consult your doctor immediately if you become pregnant while taking Endobest 2 Tab .

bannner image

Breast Feeding

Unsafe

Avoid taking Endobest 2 Tab if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

Endobest 2 Tab may cause dizziness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be necessary. Endobest 2 Tab should not be taken by people with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Endobest 2 Tab should not be given to children who have not had their first period.

Have a query?

FAQs

Endobest 2 Tab is indicated for the management of painful symptoms of endometriosis, a condition in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.

Endobest 2 Tab suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, Endobest 2 Tab helps in treating pelvic pain associated with endometriosis.

Endobest 2 Tab may cause weight gain. Maintain a healthy weight by exercising regularly. Try eating smaller but more frequent meals. Consult your doctor if you notice severe weight gain.

Do not stop taking Endobest 2 Tab on your own. Continue taking Endobest 2 Tab for as long as your doctor has prescribed it for you depending on your condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Endobest 2 Tab .

Avoid using hormonal contraceptives with Endobest 2 Tab ; instead, use non-hormonal contraceptive methods such as condoms or barrier methods. Please consult your doctor; he/she may advise regarding proper contraception.

Antibiotics and antifungal medicines might affect how Endobest 2 Tab works or might be affected by Endobest 2 Tab . Therefore, consult your doctor before taking antibiotics or antifungals with Endobest 2 Tab .

Endobest 2 Tab may cause irregular menstrual bleeding or infrequent periods. Talk to your doctor if you experience this.

Long term use of Endobest 2 Tab might lower bone mineral density and affect bone health. An adequate intake of calcium and vitamin D either via your food or supplements may be helpful.

Endobest 2 Tab should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.

Endobest 2 Tab should be swallowed as a whole with water; do not crush or chew it.

Endobest 2 Tab contains dienogest, which belongs to a group of medicines called progestin and is indicated for the management of endometriosis.

Yes, Endobest 2 Tab is a synthetic steroid.

Endobest 2 Tab helps endometriosis by suppressing the production of a hormone called estradiol, which causes excess growth in the endometrium.

Endobest 2 Tab may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Talk to your doctor if any of the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Zerico Lifesciences Pvt Ltd, 8,Solitaire Ii,Poonam Garden, Mira Road East,Mumbai. , Maharastra., Pin 401107.
Other Info - END0584

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:51 AM IST

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Reference

  1. https://www.nps.org.au/medicine-finder/visanne-tablets
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140813/

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