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Endofree Tablet 10's
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₹616
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Delivery Information
More about the Product
Composition :
DIENOGEST-2MG
Manufacturer/Marketer :
Wellesta Healthcare Pvt Ltd
Consume Type :
Oral
Expires on or after :
Jan-28
Return Policy :
Not Returnable
About Endofree Tablet 10's
Endofree Tablet 10's is an oral prescription medication used to manage painful symptoms associated with endometriosis. It helps treat pelvic pain, painful periods, and discomfort during intercourse by targeting the underlying pelvic inflammation. This medicine is designed to bring consistent relief and improve daily comfort for women experiencing these chronic symptoms.
For the best results, you must take Endofree Tablet 10's daily and consistently at the same time each day, with or without food. Establishing a strict daily routine helps maintain a steady level of the medication in your body. Along with taking this medicine, incorporating an anti-inflammatory diet and engaging in regular, gentle physical exercise can further support your recovery and pelvic health.
While taking Endofree Tablet 10's, some individuals may experience mild side effects like headaches, slight weight changes, or irregular bleeding. However, you should consult your doctor immediately if you experience serious side effects, such as sudden, severe pelvic pain, signs of blood clots, or symptoms of liver damage.
Before starting this medication, it is vital to talk to your doctor if you have certain health conditions. Do not take this if you have a history of blood clots, active liver disease, unexplained vaginal bleeding, or hormone-dependent tumours. Your doctor will help determine if this treatment is safe for your specific medical history.
Some medicines can interact with Endofree Tablet 10's, making it less effective or increasing side effects, so always share a complete list of your current medications with your healthcare provider. Additionally, smoking should be avoided as it increases the risk of blood clots, and alcohol intake should be limited to prevent liver strain. Consult your doctor if you are pregnant, breastfeeding, or planning a pregnancy, as this medicine is not suitable for these groups.
Uses of Endofree Tablet 10's
Endofree Tablet 10's is used to manage painful symptoms associated with endometriosis. The detailed uses of Endofree Tablet 10's are as follows:
- Endometriosis: Endofree Tablet 10's helps reduce the growth of endometrial tissue outside the uterus, which significantly decreases painful periods, chronic pelvic pain, and painful intercourse.
Key Benefits
Taking Endofree Tablet 10's can significantly improve your quality of life by providing targeted relief from the chronic pain caused by endometriosis. By consistently taking this medication, you can expect the following benefits:
- Effective Pain Relief: It targets and reduces severe pelvic pain and cramping, allowing you to return to your daily activities with less discomfort.
- Suppresses Tissue Growth: The active ingredient, dienogest, helps shrink and limit the growth of abnormal endometrial tissue, addressing the root cause of your symptoms.
- Non-Surgical Management: It offers a reliable, non-invasive oral treatment option to manage your symptoms without the immediate need for surgical procedures.
Side effects of Endofree Tablet
Here are the six steps to manage medication-triggered Nervousness:
- Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
- Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
- Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
- Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
- Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
- You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Dealing with Medication-Induced Headache:
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Directions for Use
- Endofree Tablet 10's can be taken with or without food as prescribed by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow Endofree Tablet 10's as a whole with a glass of water.
- Do not chew, crush, or break it.
How Endofree Tablet 10's Works
Endofree Tablet 10's contains the active ingredient dienogest, which is a human-made hormone similar to progesterone. It works by lowering the body's natural production of estrogen, a hormone that promotes the growth of endometrial tissue. By keeping estrogen levels low, Endofree Tablet 10's deprives the endometrial tissue outside the womb of the hormone it needs to grow. This leads to the shrinking of abnormal tissue, reduces inflammation in the pelvic area, and significantly relieves painful symptoms.
Alcohol
Caution
It is unknown if Endofree Tablet 10's interacts with alcohol. Please consult your doctor.
Pregnancy
Unsafe
Endofree Tablet 10's is not recommended during pregnancy. Please consult your doctor if you have any concerns regarding this. Consult your doctor immediately if you become pregnant while taking Endofree Tablet 10's.
Breast Feeding
Unsafe
Avoid taking Endofree Tablet 10's if you are breastfeeding. Please consult your doctor if you have any concerns regarding this.
Driving
Caution
Endofree Tablet 10's may cause dizziness. Do not drive or operate machinery unless you are alert.
Liver
Caution
Dose adjustment may be necessary. Endofree Tablet 10's should not be taken by people with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
Endofree Tablet 10's should not be given to children who have not had their first period.
Heart
Caution
Endofree Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Endofree Tablet 10's.
Geriatrics
Unsafe
Endofree Tablet 10's is not intended for use or prescribing in elderly patients.
What if I have taken an overdose of Endofree Tablet 10's
If you accidentally take more than your prescribed dose, seek immediate medical attention. Bring the medicine packaging with you to help the healthcare provider identify what you have taken.
Diet & Lifestyle Advise
Adopting specific diet and lifestyle habits can help you manage endometriosis symptoms more effectively while taking Endofree Tablet 10's:
- Eat an anti-inflammatory diet: Focus on foods rich in antioxidants and omega-3 fatty acids, such as leafy greens, berries, fatty fish, and flaxseeds, to help reduce pelvic inflammation.
- Engage in low-impact exercise: Regular, gentle activities like walking, swimming, or pelvic floor yoga can improve blood flow and help relieve muscle tension in the pelvis.
- Use heat therapy: Applying a heating pad or hot water bottle to your lower abdomen can help relax tight pelvic muscles and soothe cramping.
- Manage stress levels: Practice relaxation techniques such as mindfulness, deep breathing exercises, or meditation, as high stress can worsen pain perception.
- Track your symptoms: Keep a daily diary of your pain levels, bleeding patterns, and diet to help you and your doctor monitor your progress and identify personal triggers.
Have a query?
How Soon It Starts Working
The time required for Endofree Tablet 10's to start to work: Endofree Tablet 10's ideally shows its action within 1.5 to 2 hours after administration.
The time for which the effects of Endofree Tablet 10's last: The effect of Endofree Tablet 10's lasts for 24 hours.
What if you forget to take Endofree Tablet 10's
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed tablet and continue with your regular schedule. Do not take two tablets at once to make up for a missed dose. If you experience vomiting or severe diarrhea within 3 to 4 hours of taking a tablet, take another one to make sure your body absorbs the medicine properly.
Storage
•Store Endofree Tablet 10's at room temperature, between 15°C and 30°C. •Keep the tablets in their original blister pack or container to protect them from light and moisture.
Drug Warnings
- Do not take Endofree Tablet 10's if you are pregnant or breastfeeding, as it is not safe for the baby.
- Use a reliable, non-hormonal barrier method of birth control (such as condoms) while taking this medicine, as it does not guarantee protection against pregnancy.
- Avoid smoking while taking this medication, as tobacco use significantly increases your risk of developing serious blood clots.
- Watch for signs of liver damage, such as yellowing of your skin or eyes, and report these to your doctor immediately.
- Attend all scheduled follow-up appointments so your doctor can monitor your response, check your liver function, and evaluate your bone health during long-term use.
Drug-Drug Interactions
Drug-Drug Interaction Summary:
- Enzyme-inducing medications: Taking Endofree Tablet 10's with medicines used to treat epilepsy (such as carbamazepine, phenytoin, or phenobarbital) or tuberculosis (such as rifampicin) can make this medicine less effective by speeding up how your body processes it.
- Enzyme-inhibiting medications: Taking this medicine with certain antifungals (like ketoconazole or itraconazole) or antibiotics (like erythromycin) can increase the levels of the drug in your body, raising the risk of side effects.
Drug-Drug Interactions
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How does the drug interact with Endofree Tablet:
When Efavirenz is taken with Endofree Tablet, it can lower the metabolism of Endofree Tablet and increase the risk or severity of side effects.
How to manage the interaction:
Taking Efavirenz with Endofree Tablet can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
When Efavirenz is taken with Endofree Tablet, it can lower the metabolism of Endofree Tablet and increase the risk or severity of side effects.
How to manage the interaction:
Taking Efavirenz with Endofree Tablet can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Endofree Tablet:
Co-administration of Endofree Tablet with Bosentan may decrease the effectiveness of Endofree Tablet.
How to manage the interaction:
Although there is a possible interaction, Endofree Tablet can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Co-administration of Endofree Tablet with Bosentan may decrease the effectiveness of Endofree Tablet.
How to manage the interaction:
Although there is a possible interaction, Endofree Tablet can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Endofree Tablet:
Co-administration of Endofree Tablet with Mycophenolic acid may decrease the levels and action of Endofree Tablet.
How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Endofree Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
Co-administration of Endofree Tablet with Mycophenolic acid may decrease the levels and action of Endofree Tablet.
How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Endofree Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Endofree Tablet:
Taking Endofree Tablet with Primidone may increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between primidone and Endofree Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Endofree Tablet with Primidone may increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between primidone and Endofree Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DienogestFosphenytoin
Severe
How does the drug interact with Endofree Tablet:
When Endofree Tablet is taken with Fosphenytoin, it can increase the risk of severe bleeding.
How to manage the interaction:
Although taking Endofree Tablet and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
When Endofree Tablet is taken with Fosphenytoin, it can increase the risk of severe bleeding.
How to manage the interaction:
Although taking Endofree Tablet and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DienogestDantrolene
Severe
How does the drug interact with Endofree Tablet:
Co-administration of Dantrolene with Endofree Tablet can cause serious side effects that may affect your liver.
How to manage the interaction:
Taking Endofree Tablet with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Co-administration of Dantrolene with Endofree Tablet can cause serious side effects that may affect your liver.
How to manage the interaction:
Taking Endofree Tablet with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Endofree Tablet:
Taking Phenytoin with Endofree Tablet may reduce the blood levels and effects of Endofree Tablet.
How to manage the interaction:
Although taking Phenytoin and Endofree Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Endofree Tablet as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.
Taking Phenytoin with Endofree Tablet may reduce the blood levels and effects of Endofree Tablet.
How to manage the interaction:
Although taking Phenytoin and Endofree Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Endofree Tablet as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Endofree Tablet:
Taking carbamazepine with Endofree Tablet may increase the effect of carbamazepine.
How to manage the interaction:
Although there is a possible interaction, Endofree Tablet can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
Taking carbamazepine with Endofree Tablet may increase the effect of carbamazepine.
How to manage the interaction:
Although there is a possible interaction, Endofree Tablet can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interaction Summary:
- Grapefruit and grapefruit juice: Avoid consuming grapefruit while on this medication, as it can block the enzymes that break down the drug, leading to higher levels in your blood and increasing the risk of side effects.
DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Endofree Tablet with Grapefruit and Grapefruit juice may increase the side effects of Endofree Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Endofree Tablet.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Endofree Tablet with Grapefruit and Grapefruit juice may increase the side effects of Endofree Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Endofree Tablet.
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FAQs
Endofree Tablet 10's is indicated for the management of painful symptoms of endometriosis, a condition in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.
Endofree Tablet 10's suppresses the production of a hormone called estradiol, which causes excess growth of the endometrium. Thereby, Endofree Tablet 10's helps in treating pelvic pain associated with endometriosis.
Endofree Tablet 10's may cause weight gain. Maintain a healthy weight by exercising regularly. Try eating smaller but more frequent meals. Consult your doctor if you notice severe weight gain.
Do not stop taking Endofree Tablet 10's on your own. Continue taking Endofree Tablet 10's for as long as your doctor has prescribed it for you, depending on your condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Endofree Tablet 10's.
Avoid using hormonal contraceptives with Endofree Tablet 10's; instead, use non-hormonal contraceptive methods such as condoms or barrier methods. Please consult your doctor; he/she may advise regarding proper contraception.
Antibiotics and antifungal medicines might affect how Endofree Tablet 10's works or might be affected by Endofree Tablet 10's. Therefore, consult your doctor before taking antibiotics or antifungals with Endofree Tablet 10's.
Endofree Tablet 10's may cause irregular menstrual bleeding or infrequent periods. Talk to your doctor if you experience this.
Long-term use of Endofree Tablet 10's might lower bone mineral density and affect bone health. An adequate intake of calcium and vitamin D, either via your food or supplements, may be helpful.
Endofree Tablet 10's should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.
Endofree Tablet 10's should be swallowed as a whole with water; do not crush or chew it.
Endofree Tablet 10's contains dienogest, which belongs to a group of medicines called progestin and is indicated for the management of endometriosis.
Yes, Endofree Tablet 10's is a synthetic steroid.
Endofree Tablet 10's helps endometriosis by suppressing the production of a hormone called estradiol, which causes excess growth in the endometrium.
Endofree Tablet 10's may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Talk to your doctor if any of the side effects persist or worsen.
Occasional, moderate alcohol consumption is generally safe, but drinking alcohol excessively can put extra strain on your liver and may increase the risk of certain side effects. To protect your liver, it is best to limit alcohol. Talk to your doctor or pharmacist if you have concerns.
Because this medication lowers estrogen levels, long-term use can sometimes lead to a slight decrease in bone mineral density. Your doctor may check your bone health if you take it for an extended period. Talk to your doctor about whether you should take calcium and vitamin D supplements.
If you vomit or experience severe diarrhoea within 3 to 4 hours of taking your Endofree Tablet 10's tablet, the active ingredient may not have been fully absorbed. In this case, you should take another tablet as soon as possible, and then continue your regular schedule. Talk to your doctor or pharmacist if you are unsure.
No, this medication is not recommended for use while breastfeeding, as active hormones can pass into breast milk and affect the nursing infant. Talk to your doctor to explore alternative treatments that are safe during breastfeeding.
No, you should not stop taking this medication suddenly or without consulting your healthcare provider. Stopping the treatment prematurely can cause your endometriosis tissue to grow again, leading to the return of painful symptoms. Talk to your doctor before making any changes.
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Reference
- National Center for Biotechnology Information (NCBI). Pmc3140813 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
- Dineogest Dineogest. 2008. [Accessed on 04 Apr. 2019]Check here
- Endometriosis [Internet]. Who.int. 2021 [Accessed on 4 April 2022]Check here
- Visanne Tablets. [Accessed on 02 Jun. 2026]Check here
- Dienogest [Product Monograph]. 2022. [Accessed on 20 June 2023]Check here
- PrVISANNE® dienogest tablets [Internet]. Pdf.hres.ca. 2021 [Accessed on 4 April 2022]Check here
- VISANNE Tablets [Internet]. Bayer.com. 2021 [Accessed on 4 April 2022]Check here
Country of origin
India
Manufacturer/Marketer address
Unit 3A, Level 2, The Centrium Phoenix Market City Complex, Lbs Road, Kurla West Mumbai Mumbai City Mh 400070 In
Therapeutic Class
[PROGESTIN]
Habit Forming
No
Other Info - END0861
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