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ENDOXAN N INJECTION 1GM

Manufacturer/Marketer

GERMAN REMEDIES LIMTED

Consume Type

PARENTERAL

In Stock

Prescription Required
Product Details

About ENDOXAN N INJECTION 1GM

ENDOXAN N INJECTION 1GM belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, ENDOXAN N INJECTION 1GM is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
ENDOXAN N INJECTION 1GM contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. ENDOXAN N INJECTION 1GM suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, ENDOXAN N INJECTION 1GM may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. ENDOXAN N INJECTION 1GM may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of ENDOXAN N INJECTION 1GM

Malignant diseases (cancer), nephrotic syndrome (kidney disease)

Medicinal Benefits

ENDOXAN N INJECTION 1GM belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. ENDOXAN N INJECTION 1GM works by stopping or slowing the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. Additionally, ENDOXAN N INJECTION 1GM is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. ENDOXAN N INJECTION 1GM suppresses the body's immune system, thereby helping treat nephrotic syndrome.

Directions for Use

ENDOXAN N INJECTION 1GM will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ENDOXAN N INJECTION 1GM

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

In-Depth Precautions and Warning

Drug Warnings

Do not take ENDOXAN N INJECTION 1GM if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. ENDOXAN N INJECTION 1GM may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Drug Interactions

Drug-Drug Interactions: ENDOXAN N INJECTION 1GM may have interaction with protease inhibitors, ACE inhibitors, immunomodulators (natalizumab), chemotherapy agents (paclitaxel), thiazide diuretics, anti-HIV (zidovudine), antiarrhythmics (amiodarone), anti-fungal (amphotericin B), NSAID (indomethacin), immunosuppressant (azathioprine), alkylating agents (busulfan).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow or obstruction.

Drug-Drug Interactions Checker List:

  • NATALIZUMAB
  • PACLITAXEL
  • ZIDOVUDINE
  • AMIODARONE
  • AMPHOTERICIN B
  • INDOMETHACIN
  • AZATHIOPRINE
  • BUSULFAN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption as it may worsen the risk of cyclophosphamide-induced nausea and vomiting.

    • Safety Warning

      Pregnancy

      caution

      It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Avoid breastfeeding during treatment with ENDOXAN N INJECTION 1GM and for one week after the last dose.

    • Safety Warning

      Driving

      caution

      ENDOXAN N INJECTION 1GM may cause dizziness. Do not drive or operate heavy machinery until you are alert.

    • Safety Warning

      Liver

      caution

      If you have a pre-existing or a history of liver disease, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Kidney

      caution

      If you have a history of kidney diseases, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Children

      consult your doctor

      Please consult your doctor. Your doctor will with the benefits and risks before prescribing this medicine based on your child's medical condition.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a healthy diet and exercise regularly to maintain proper weight.
    • Avoid smoking and alcohol consumption.
    • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
    • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
    • Get optimal sleep; rest well.

    Special Advise

    • Monitoring of complete blood count whilst on treatment with ENDOXAN N INJECTION 1GM is advised.
    • Women of childbearing potential must use highly effective contraception during treatment and for up to 1 year after the last dose.
    • Male patients who are sexually active with a female partner of child-bearing potential must use condoms during treatment and for up to 6 months after the last dose.

    Other Information (END0004)

    This item is Not Returnable.

    Expires on or after - Apr-24

    Patients Concern

    Disease/Condition Glossary

    Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner leading to the formation of tumours. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy and targeted drug therapy.

    Nephrotic syndrome: It is a kidney disorder in which the body excretes too much protein in the urine. Symptoms include foamy urine, weight gain, and swelling around the eyes and in the ankles and feet.

    FAQs

    How does ENDOXAN N INJECTION 1GM work?

    ENDOXAN N INJECTION 1GM works by stopping or slowing down the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. ENDOXAN N INJECTION 1GM suppresses the body's immune system and helps treat nephrotic syndrome.

    Does ENDOXAN N INJECTION 1GM cause infertility?

    ENDOXAN N INJECTION 1GM might impair fertility and interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm). Please consult your doctor if you have any concerns.

    Is it safe to father a child while on treatment with ENDOXAN N INJECTION 1GM?

    Men should avoid fathering a child during the treatment and for six months following discontinuation of therapy.

    Does ENDOXAN N INJECTION 1GM interfere with wound healing?

    ENDOXAN N INJECTION 1GM might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding or bruising or if the wounds do not heal properly.

    PRODUCT SUBSTITUTES

    ENDOXAN N INJECTION 1GM

    Country Of Origin

    India

    Manufacturer/Marketer address

    Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.

    Disclaimer

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    Price :₹238.40

    MRP ₹280.50

    15%off

    (Inclusive of all taxes)

    Provide Delivery Location

    Vial

    1 Injection in 1 Vial