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Entechlor 500mg Capsule is used to treat bacterial infections. It contains Chloramphenicol, which kills the infection-causing bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, and headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Suzikem Drugs Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Entechlor 500mg Capsule

Entechlor 500mg Capsule is a prescription antibiotic capsule used to treat severe, life-threatening bacterial infections such as typhoid fever and certain types of meningitis. It is typically prescribed only when other, safer antibiotics cannot be used or have failed to work. This medicine works directly against the bacteria causing the illness to help control and resolve the infection.

To work effectively, you must take Entechlor 500mg Capsule consistently at evenly spaced intervals throughout the day and night as directed by your doctor. It is best to take this medicine on an empty stomach, either 1 hour before or 2 hours after a meal, with a full glass of water. Eating a balanced, nutrient-rich diet and getting plenty of rest can also support your body’s immune system during recovery.

While taking Entechlor 500mg Capsule, you may experience mild side effects like nausea, vomiting, or diarrhoea. However, you must contact your doctor immediately if you experience more serious symptoms such as severe fatigue, pale skin, a persistent sore throat, or unusual bruising. These serious signs can point to problems with how your body produces blood cells.

Do not take this if you are allergic to this medication or if you have a history of bone marrow disorders or blood problems. Before starting this medication, talk to your doctor if you have kidney disease, liver damage, or a genetic condition called G6PD deficiency. This medicine should not be used by pregnant women, especially close to childbirth, or by breastfeeding mothers.

Entechlor 500mg Capsule can interact with other medicines, such as blood thinners or seizure medications, which may increase the risk of serious side effects. Avoid drinking alcohol while taking this medication, as it can worsen stomach upset and strain your liver. If you are an elderly individual, consult your doctor or pharmacist to ensure this medicine is appropriate for your specific health needs.

Uses of Entechlor 500mg Capsule

Entechlor 500mg Capsule is an antibiotic used to treat certain serious bacterial infections caused by susceptible bacteria.

  • Typhoid fever: Entechlor 500mg Capsule helps clear severe enteric infections when other standard antibiotics are not suitable or effective.
  • Bacterial meningitis: Entechlor 500mg Capsule treats severe infections of the membranes covering the brain and spinal cord by stopping bacterial growth.
  • Rickettsial infections: Entechlor 500mg Capsule may be used to treat infections such as scrub typhus or Rocky Mountain spotted fever in patients who cannot take first-line treatment, such as doxycycline.
  • Other severe bacterial infections: Entechlor 500mg Capsule targets serious systemic infections where the bacteria are proven to be susceptible and alternative treatments have failed.

Key Benefits

Entechlor 500mg Capsule helps treat serious bacterial infections by stopping the growth of bacteria and preventing the infection from spreading.

  • Helps Control Severe Bacterial Infections: Entechlor 500mg Capsule provides life-saving therapy for patients suffering from severe and dangerous bacterial infections. By quickly stopping bacterial growth, it helps prevent the infection from spreading to vital organs, supporting recovery from severe illness and high fevers.
  • Excellent Penetration into the Brain and Spinal Cord: Another major benefit of Entechlor 500mg Capsule is its excellent tissue penetration. Unlike many other antibiotics, it can cross the blood-brain barrier, making it highly effective at delivering targeted treatment to the brain and spinal cord during severe nervous system infections.

Directions for Use

  • Entechlor 500mg Capsule can be taken on an empty stomach, either 1 hour before or 2 hours after meals, as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Entechlor 500mg Capsule as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Entechlor 500mg Capsule Works

Entechlor 500mg Capsule contains Chloramphenicol, an antibiotic that is predominantly bacteriostatic, meaning it usually stops bacteria from multiplying. However, against certain susceptible bacteria, including some that cause meningitis, it may act as a bactericidal antibiotic. It does this by entering the bacterial cells and binding to their protein-making machinery. By blocking the bacteria's ability to produce essential proteins needed for their growth and survival, the medicine effectively halts the spread of the infection. This gives your body's natural immune system the time and strength it needs to destroy and clear the remaining bacteria from your system.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Entechlor 500mg Capsule. Please consult a doctor if you have concerns.

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Pregnancy

Unsafe

Do not take Entechlor 500mg Capsule if you are pregnant as it may harm your foetus. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Do not take Entechlor 500mg Capsule if you are breastfeeding as it may pass into breast milk and harm your infant. Please consult your doctor if you have any concerns.

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Driving

Safe if prescribed

Entechlor 500mg Capsule does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have liver impairment/liver disease before taking Entechlor 500mg Capsule.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment/kidney disease before taking Entechlor 500mg Capsule.

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Children

Consult your doctor

Entechlor 500mg Capsule should be used for children only if advised by the doctor.

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Heart

Caution

Entechlor 500mg Capsule should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Entechlor 500mg Capsule.

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Geriatrics

Caution

Limited data is available regarding the use of Entechlor 500mg Capsule in elderly patients. If you have any concerns about the usage of Entechlor 500mg Capsule in geriatrics, please consult your doctor.

What if I have taken an overdose of Entechlor 500mg Capsule

Symptoms of an overdose may include severe nausea, vomiting, confusion, breathing difficulties, or seizures. Bluish discolouration of the skin and lips (cyanosis) is mainly associated with Gray Baby Syndrome, a rare but serious toxicity seen in newborns.

Diet & Lifestyle Advise

  • Stay Well Hydrated: Drink plenty of fluids, such as water or clear broths, to stay hydrated, especially if you experience diarrhoea during treatment.
  • Avoid Alcohol: Do not drink alcohol while taking Entechlor 500mg Capsule, as it may increase the risk of stomach upset and headaches.
  • Eat Small, Frequent Meals: If you experience mild nausea or stomach discomfort, try eating smaller meals more often instead of large meals.
  • Support Gut Health: Consider taking a high-quality probiotic or eating fermented foods, such as yoghurt with active cultures, a few hours after your dose to help restore healthy gut bacteria affected by the antibiotic.
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How Soon It Starts Working

The time required for Entechlor 500mg Capsule to start to work: The time required for Entechlor 500mg Capsule to show its action is unknown. The time for which the effects of Entechlor 500mg Capsule last: The effect of Entechlor 500mg Capsule lasts for 15 hours.

What if you forget to take Entechlor 500mg Capsule

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you miss multiple doses.

Storage

• Store Entechlor 500mg Capsule capsules at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Complete the Full Course: Finish the entire course of treatment exactly as prescribed, even if your symptoms improve or disappear, to help prevent the infection from returning.
  • Attend Regular Blood Tests: Undergo regular blood tests (complete blood counts) as directed by your doctor to monitor your bone marrow health during treatment.
  • Use Only for Prescribed Infections: Do not take Entechlor 500mg Capsule for minor viral illnesses such as the common cold, flu, or simple sore throat, as it is intended for serious bacterial infections.
  • Inform Your Healthcare Provider: Tell your doctor, dentist, or any other healthcare provider that you are taking Entechlor 500mg Capsule before any medical procedure or before starting new medicines.
  • Seek Medical Help for Serious Symptoms: Get immediate medical attention if you develop sudden pale skin, severe fatigue, a sore throat, or unexpected bleeding, as these may indicate a serious side effect.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Entechlor 500mg Capsule: 

  • Blood thinners (like warfarin): Entechlor 500mg Capsule can increase the effect of these medicines, raising your risk of bleeding.
  • Seizure medicines (like phenytoin or phenobarbital): Entechlor 500mg Capsule can increase the levels of these drugs in your blood, which may lead to toxicity.
  • Medicines that affect bone marrow (like chemotherapy drugs): Combining these with Entechlor 500mg Capsule can severely increase the risk of serious blood disorders.
Critical
ChloramphenicolFlibanserin
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Entechlor 500mg Capsule:
Taking Entechlor 500mg Capsule with triazolam can increased the effects of Entechlor 500mg Capsule.

How to manage the interaction:
Taking Triazolam with Entechlor 500mg Capsule is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
ChloramphenicolFlibanserin
Critical
How does the drug interact with Entechlor 500mg Capsule:
Taking Flibanserin with Entechlor 500mg Capsule may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Entechlor 500mg Capsule with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.
ChloramphenicolLomitapide
Critical
How does the drug interact with Entechlor 500mg Capsule:
Taking lomitapide with Entechlor 500mg Capsule can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Entechlor 500mg Capsule with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Entechlor 500mg Capsule:
Taking Entechlor 500mg Capsule and Ivacaftor may increase the blood levels of ivacaftor that increases risk of side effects.

How to manage the interaction:
Although taking Entechlor 500mg Capsule and Ivacaftor together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Entechlor 500mg Capsule:
Taking Entechlor 500mg Capsule and Butorphanol can significantly increase the blood levels of Butorphanol that may increase the risk of side effects.

How to manage the interaction:
Although taking Entechlor 500mg Capsule with Butorphanol can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures contact your doctor know. Do not stop using any medications without a doctor's advice.
How does the drug interact with Entechlor 500mg Capsule:
When Everolimus is taken with Entechlor 500mg Capsule that may increase the risk of side effects.

How to manage the interaction:
Co-administration of Entechlor 500mg Capsule with Everolimus can result in an interaction, but it can be taken if a doctor has advised it. If you experience any unusual symptoms like persistent cough, fever, chills, mouth ulcers, paleness, unusual bruising, bleeding or blood in stools or urine, it's important to contact a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Entechlor 500mg Capsule:
Taking Naloxegol and Entechlor 500mg Capsule can significantly increase the blood levels of naloxegol that may increase the risk of side effects.

How to manage the interaction:
Although taking Entechlor 500mg Capsule and Naloxegol together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sweating, runny nose, or abdominal pain contact your doctor know right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Entechlor 500mg Capsule:
Taking Entechlor 500mg Capsule and Deferiprone may increase the risk of infections.

How to manage the interaction:
Taking Entechlor 500mg Capsule with Deferiprone together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
ChloramphenicolVoclosporin
Severe
How does the drug interact with Entechlor 500mg Capsule:
Taking Entechlor 500mg Capsule with Voclosporin can increase the blood levels of voclosporin which increases risk of serious side effects.

How to manage the interaction:
Although taking Entechlor 500mg Capsule and Voclosporin together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any unusual symptoms, it's important to contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Entechlor 500mg Capsule:
Co-administration of acalabrutinib with Entechlor 500mg Capsule can significantly increases the blood levels of acalabrutinib.

How to manage the interaction:
Although there is a interaction between Entechlor 500mg Capsule and Acalabrutinib, but it can be taken together if prescribed by your doctor. However, if you experience symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination, call your doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Entechlor 500mg Capsule when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Entechlor 500mg Capsule works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating and preventing the spread of infections.
Diarrhoea might be a side-effect Entechlor 500mg Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Entechlor 500mg Capsule should only be used for as long as your doctor prescribes. Prolonged use may increase the risk of side effects, including blood disorders and nerve problems, so your doctor may recommend regular monitoring during extended treatment. Do not continue taking it longer than prescribed without medical advice.
It is highly recommended to avoid alcohol while taking Entechlor 500mg Capsule. Alcohol can worsen stomach upset and increase the risk of side effects like nausea, vomiting, or headaches. Talk to your doctor or pharmacist if you have concerns.
Yes. In some people, particularly during prolonged treatment, Entechlor 500mg Capsule may affect the bone marrow and reduce blood cell counts, increasing the risk of infections, slow healing, bleeding, or anaemia. Your doctor may recommend regular blood tests to monitor your blood cell counts and ensure the medicine is being used safely.
No, Entechlor 500mg Capsule should not be taken during pregnancy, especially during the late stages, as it can cause serious, life-threatening side effects in the unborn baby. Always tell your doctor if you are pregnant or planning to become pregnant.
Do not stop taking Entechlor 500mg Capsule without your doctor's advice, even if you start feeling better. Stopping treatment too early can allow bacteria to survive, causing the infection to return and increasing the risk of antibiotic resistance. Complete the full course exactly as prescribed. If you are unable to continue because of side effects or other concerns, speak to your doctor.
No, Entechlor 500mg Capsule is an antibiotic and only works against bacterial infections. It is not effective against viral infections like colds, flu, or bronchitis. Using it unnecessarily can lead to serious risks and bacterial resistance.
It is generally recommended to take Entechlor 500mg Capsule on an empty stomach, 1 hour before or 2 hours after a meal, for better absorption. However, if it causes stomach upset, your doctor may advise taking it with a light meal. Always follow your doctor's instructions.
Yellowing of the skin or eyes can be a sign of a serious problem affecting your liver or blood. Seek immediate medical attention without delay. A doctor will assess your condition and advise whether Entechlor 500mg Capsule should be stopped or your treatment changed.
Yes, in some cases, prolonged use of Entechlor 500mg Capsule can cause nerve issues leading to numbness, tingling, or burning sensations in your hands or feet. Contact your doctor immediately if you experience these symptoms.

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Country of origin

India
Other Info - EN59253
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